• The Korean Journal of Food And Nutrition
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• v.33 no.3
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• pp.347-355
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• 2020

Cognitive impairment is considered to be key research topics in the field of neurodegenerative diseases and in understanding of learning and memory. In the present study, we investigated neuroprotective effects of Schisandra chinensis (SC) and Ribes fasciculatum (RF) extracts in hydrogen peroxide-induced neuronal cell death in vitro and scopolamine-induced cognitive impairment in Sprague Dawley^® (SD) rat in vivo. Apoptotic cell death in neuroblastic PC12 cell line was induced by hydrogen peroxide for 1 hour at 100 μM. However, mixture of SC and RF treatment prevented peroxide induced PC12 cell death with no neurotoxic effects. For in vivo experiment, the effect of SC and RF extracts on scopolamine-induced cognitive impairment in SD rat was evaluated by spontaneous alternation behavior in Y-Maze test. After 30 min scopolamine injection, the scopolamine-induced rats presented significantly decreased % spontaneous alteration and acetylcholine level, compared to non-induced group. However, treatment of SC+RF extracts rescued the reduced % spontaneous alteration with acetylcholine concentration from hippocampus in scopolamine-induced rats. These results suggested that mixture of SC and RF extract may be a potential natural therapeutic agent for the prevention of cognitive impairment.

• The Plant Pathology Journal
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• v.20 no.2
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• pp.106-109
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• 2004

A leaf blight disease was found on Ailanthus altissiman growing in the Manchon Mountain Park in Daegu city. When isolated, the causal fungus readily formed sex organs, being homothallic. Oogonia were spherical, 19.5-42.9 ${\mu}{\textrm}{m}$ in diameter with an average of 29.4$\pm$4.2 ${\mu}{\textrm}{m}$. Antheridia were amphigynous, round to ovoid, and measured 11.3-15.0 ${\mu}{\textrm}{m}$ long and 12.5-14.5 ${\mu}{\textrm}{m}$ wide. Oospores in the oogonia were spherical, 26.1-29.0 ${\mu}{\textrm}{m}$ in diameter. Sporangia that formed in water were spherical to sub-spherical with a conspicuous papilla and measured 19.5-56.6 ${\times}$ 15.6-44.9 ${\mu}{\textrm}{m}$ with an average of 44.0$\pm$8.7${\times}$32.7$\pm$6.3 ${\mu}{\textrm}{m}$. The mean length/breadth (I/b) ratio was 1.35. Papillae were 3.9-11.7 ${\mu}{\textrm}{m}$l high and 3.9-9.8 ${\mu}{\textrm}{m}$ wide. Sporangia formed slowly on V8 juice agar medium when cultured under fluorescent light at 12-hour alternation. The sporangia that formed on the agar medium were more spherical and measured 26.5-39.0${\times}$23.4-35.1 ${\mu}{\textrm}{m}$ with an average of 33.6$\pm$3.4${\times}$28.2$\pm$3.2 ${\mu}{\textrm}{m}$ and I/b ratio of 1.19. Disease symptom was repro-duced by artificial inoculation of the healthy plants with the isolate. The causal organism was identified as Phyto-phthora boehmeriae on the basis of its morphological characteristics.

• The Mathematical Education
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• v.46 no.1 s.116
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• pp.53-67
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• 2007

During the recent years at a middle level Engineering School located at the local areas in Korea, more than 20 percent of freshmen had failed at their first College Mathematics. In consequence, many of them had hard time to survive at their major curriculums. The purpose of this study is to look for the main reasons of their failure and suggest an alternation of the present curriculum. Using the responses to the questionnaires and placement test scores, we studied the characteristics of the students' Mathematical abilities and analyzed how they were related to their grades of the First College Mathematics at the end of the first semester. The mathematical ability of the students at the middle level Engineering School turned out to range from bottom to top even though most of them revealed their interests towards Mathematics. The students with low scores at the placement test were more likely to fail at their first College Mathematics. Thus we suggest that the school should open a new preparation course ahead of the First College Mathematics for those who achieve low scores at the placement test and also professors should write proper books and develop ways of teaching.

• Proceedings of the Korean Vacuum Society Conference
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• 2012.02a
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• pp.158-158
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• 2012

A new kind of organic-inorganic hybrid polymer, poly(tetraphenyl)silole siloxane (PSS), was invented and synthesized for realization of its unique charge trap properties. The organic portions consisting of (tetraphenyl)silole rings are responsible for electron trapping owing to their low-lying LUMO, while the Si-O-Si inorganic linkages of high HOMO-LUMO gap provide the intrachain energy barrier for controlling electron transport. Such an alternation of the organic and inorganic moieties in a polymer may give an interesting quantum well electronic structure in a molecule. The PSS thin film was fabricated by spin-coating of the PSS solution in THF organic solvent onto Si-wafer substrates and curing. The electron trapping of the PSS thin films was confirmed by the capacitance-voltage (C-V) measurements performed within the metal-insulator-semiconductor (MIS) device structure. And the quantum well electronic structure of the PSS thin film, which was thought to be the origin of the electron trapping, was investigated by a combination of theoretical and experimental methods: density functional theory (DFT) calculations in Gaussian03 package and spectroscopic techniques such as near edge X-ray absorption fine structure spectroscopy (NEXAFS) and photoemission spectroscopy (PES). The electron trapping properties of the PSS thin film of quantum well structure are closely related to intra- and inter-polymer chain electron transports. Among them, the intra-chain electron transport was theoretically studied using the Atomistix Toolkit (ATK) software based on the non-equilibrium Green's function (NEGF) method in conjunction with the DFT.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.24 no.2
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• pp.51-55
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• 1979

The effects of vernalization and darkness on flower initiation were reviewed by using naked barley varieties. The dark effects were pronounced on flower induction even at 25$^{\circ}C$. There were no differences in flowering responses among varieties. The effects of vernalization and darkness combined with 25$^{\circ}C$were 100% and 60% respectively which showed a significant difference. When the alternation of darkness with light was taken as first and last the flowering rate was 92 percent. When it was intercalated by light treatments the flowering rate was 91 per cent. Thus the effects of vernalization and darkness seems to differ.

• Economic and Environmental Geology
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• v.30 no.3
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• pp.263-275
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• 1997

Compound calcrete deposits are recognized from the Dadaepo Formation in Dusong peninsula, Pusan, and their textures, structures, morphology, and stratigraphic distribution are examined. The Dadaepo Formation in study area consists of fluvial plain deposits including floodplain-lake deposits, and the compound calcrete deposits occur above floodplain deposits and below lacustrine deposits. The compound calcrete deposits are composed of nodular to massive (micritic), laminar, nodular, nodular to massive (marly), and marly calcrete deposits. In these calcretes, circumgranular and curved cracks, alveolar structures, fitted peloids, tubular fenestrae with laminar micrite wall (rootlet casts), microstalactic calcite, and tepee structures are observed, which indicates that they are calcic paleosols. Considering their stratigraphic occurrences and pedogenic origin, compound calcrete deposits are interpreted to have formed on distal fluvial plain to palustrine environment by the repetetion of deposition and subsequent calcification due to alternation of lake expansion and contraction. The repetetion of calcrete formation suggests that arid climatic condition was alternated with humid condition in short-term period. Such alternated paleoclimatic condition is similar to those of the Sindong and Hayang groups, and indicates that short-term fluctuations from arid to humid climate were prevailing in overall Gyeongsang Basin. In stratigraphic sense, the compound calcrete deposits can be used as a marker deposit for the correlation of the Dadaepo Formation.

• Journal of the Korea Society of Computer and Information
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• v.17 no.3
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• pp.59-66
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• 2012

In daily life if a condoler receive a notice of a person's death who he/she know, he/she generally have the deepest regret and offer condolence money. Also an enterpriser or private chairman send a floral tribute. But it has some problem to occur a abuse according in reuse and an environmental pollution in process of trash. In this paper it is suggested an business model for the condolence service using images, floral tributes and letters of condolence made of images, in the funeral place which is an alternation to reduce the problem. And it is structured and implemented a service model that displays floral tributes made of dynamic images to a large monitor installed on wall in condoler room of funeral place. As a result it is showed that a service of floral tributes made of images may be realized to be given web site of servicing images for the condolence.

• Journal of the Korean Society of Marine Environment & Safety
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• v.24 no.5
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• pp.591-596
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• 2018

In Designing a Small Ship, the Design of the Trim for Sailing has a great influence on the Stability of the Ship as well as Resistance. The Center of Gravity of a Ship is mostly determined during Initial Design. This Study confirms the Effect of Trim on changes in Vertical Center of Gravity by Numerical Analysis for a Small Catamaran. The Results were examined in a Model test. However, No Model tests were conducted while varying the changes in Vertical Center of Gravity. Nonetheless, Investigation was completed for the Purpose of presenting Vertical Center of Gravity results according to plans for the Trim during Initial Design of a Small Ship. In order to verify the Results of Numerical Analysis, a Comparison with Experimental results was carried out. Alternation of Trim angle and Resistance performance according to changes in the Center of Gravity were studied.

• Journal of Haehwa Medicine
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• v.15 no.2
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• pp.135-148
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• 2006

Sophorae Radix (SFR) is known as a therapeutic drug that has been used in Oriental traditional medicine for the treatment of skin and mucosal ulcers, gastrointestinal hemorrhage, diarrhea, inflammation and arrhythmia. In the present study, we examined the effects of the aqueous extract of SFR on anti-inflammation, anti-allergic and anti-oxidant effect in various cell lines; they include mouse lung fibroblast cells (hFCs), human mast cells (HMC-1), human monocytic cells (THP-1), and RAW 264.7 cells. Treatment with SFR extract at a concentration of 250 ${\mu}g$/ml for 24h showed no significant decrease in the survival rate of the hFCs. SFR decreased the mRNA expression of IL-8, TNF-$\alpha$, and IL-6 in HMC-1 cells. SFR extract treatment significantly inhi-bited the protein expression of IL-6 and, IL-8 induced by mite in THP-1 cells and it also did MCP-1 expression. We examined the alternation of histamine release in HMC-1 cells for investigating anti-allergic effect of SFR. Histamine secretion decreased after the treatment with SFR. In addition, SFR extract treatment at a concentration of 10 ${\mu}g$/ml, 100 ${\mu}g$ /ml, and 200 ${\mu}g$/ml lowered the $\beta$-hexosaminidase to 10.3%, 21.7%, and 50.8%, respectively. IC50 of SFR extract in RBL-2H3 cells was 196.85 ${\mu}g$/ml. Both activity of NF-$\kappa$B promoter in RBL-2H3 cells significantly diminished after the dose-dependent treatment of SFR. Therefore, our results indicate that SFR has anti-inflammatory and it may be useful for treating allergic diseases such as atopic dermatitis.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.5
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• pp.929-934
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• 2009

In this work, the punchless piercing process with application of alternate high pressure has been proposed as a method to obtain pierced holes having nearly vertical wall over thin metal plates. The numerical simulation considering Lemaitre damage model has been accomplished for the proposed method. The simulated results have been compared with those by conventional one-way punch less piercing process. It has been revealed that the fractured section made by pressure alternation method shows nearly steep wall where the deviation angle from the vertical line is as small as $3.6^{\circ}$.