• Nuclear Engineering and Technology
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• v.56 no.5
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• pp.1638-1653
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• 2024

Given the unpredictability of the occurrence of the earthquake and other potential disasters into consideration, the nuclear power plant may be confronted with beyond design-basis earthquake load in the future. The containment structure may be severely damaged under such severe earthquake loading, increasing the risk of containment concrete cracking and potential radioactive materials leaking. Moreover, initial damage caused by the earthquake may significantly alter the pressure performance of the containment under follow-up internal pressure. To compromise the dangers of beyond design-basis earthquake to the containment, an alternative of replacing the conventional concrete with fiber-reinforced concrete (FRC) to upgrade the seismic resistance capacity of the containment is attempted and thoroughly researched. In this study, the influence of various fiber types such as rigid fiber and mixed fiber is regarded to constitute fiber-reinforced PCCVs. The physical properties of traditional and fiber-reinforced PCCVs under earthquake ground motions are scientifically compared and identified by using traditional and proposed evaluation indices. The results indicate that both the traditional evaluation index (i.e. top displacement, stress, strain) and the proposed damage index are greatly reduced by the practice of fiber strengthening under earthquake ground motions.

• Molecules and Cells
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• v.26 no.5
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• pp.503-513
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• 2008

The vomeronasal organ (VNO) is a sensory organ that influences social and/or reproductive behavior and, in many cases, the survival of an organism. The VNO is believed to mediate responses to pheromones; however, many mechanisms of signal transduction in the VNO remain elusive. Here, we examined the expression of proteins involved in signal transduction that are found in the main olfactory system in the VNO. The localization of many signaling molecules in the VNO is quite different from those in the main olfactory system, suggesting differences in signal transduction mechanisms between these two chemosensory organs. Various signaling molecules are expressed in distinct areas of VNO sensory epithelium. Interestingly, we found the expressions of groups of these signaling molecules in glandular tissues adjacent to VNO, supporting the physiological significance of these glandular tissues. Our finding of high expression of signaling proteins in glandular tissues suggests that neurohumoral factors influence glandular tissues to modulate signaling cascades that in turn alter the responses of the VNO to hormonal status.

• The KIPS Transactions:PartC
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• v.11C no.4
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• pp.419-428
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• 2004

Due to the deployment problem of the IP Multicast service, the Application Layer Multicast (or Overlay Multicast) has appeared as an alter-native of the If Multicast. However, even though plenty of the Application Layer Multicast (ALM) Protocols were designed and their applications were developed according to the diverse requirements of each multicast service, researches on the ALM Protocols are focused on only a protocol design or an efficient multicast group management algorithm. And there is little effort to provide a unified guideline for development of the ALM Protocols and provide an environment for running multiple protocols simultaneously in a system. In this paper, we propose socket APIs to be a reference in developing new ALM Protocols which enables a system to support multiple protocols in a system with other ALM Protocols and which gives an environment to support efficient protocol management.

• Asian-Australasian Journal of Animal Sciences
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• v.29 no.8
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• pp.1075-1082
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• 2016

Modern livestock production became highly intensive and large scaled to increase production efficiency. This production environment could add stressors affecting the health and growth of animals. Major stressors can include environment (air quality and temperature), nutrition, and infection. These stressors can reduce growth performance and alter immune systems at systemic and local levels including the gastrointestinal tract. Heat stress increases the permeability, oxidative stress, and inflammatory responses in the gut. Nutritional stress from fasting, antinutritional compounds, and toxins induces the leakage and destruction of the tight junction proteins in the gut. Fasting is shown to suppress pro-inflammatory cytokines, whereas deoxynivalenol increases the recruitment of intestinal pro-inflammatory cytokines and the level of lymphocytes in the gut. Pathogenic and viral infections such as Enterotoxigenic E. coli (ETEC) and porcine epidemic diarrhea virus can lead to loosening the intestinal epithelial barrier. On the other hand, supplementation of Lactobacillus or Saccharaomyces reduced infectious stress by ETEC. It was noted that major stressors altered the permeability of intestinal barriers and profiles of genes and proteins of pro-inflammatory cytokines and chemokines in mucosal system in pigs. However, it is not sufficient to fully explain the mechanism of the gut immune system in pigs under stress conditions. Correlation and interaction of gut and systemic immune system under major stressors should be better defined to overcome aforementioned obstacles.

• Journal of Korean Tunnelling and Underground Space Association
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• v.7 no.3
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• pp.239-247
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• 2005

A new railway line of about 17km length was planned between Dongbaeksan and the neighboring town Dokye to improve the existing decrepit railway system. New line about 17km of the distance will almost be in circular alignment tunnels owing to the difference of elevation about 380m. Since the geology of the area is rather unusual compared to the normal in South Korea, extensive geological investigations have been carried out to prepare geological maps and profiles along the planned tunnel routes. The tunnel will almost be in sedimentary rock formations, such as limestone, sandstone, shale, coal etc and be near abandoned mines Various rock formations have the complicated, alter ed those rocks, but are well developed with laminated formations. Each rock formations have been classified using the Q-system and the cost of tunnel excavation, support has been estimated and compared for three alternative routes in the design stage. Based on these estimates, the final route of t he railway line was chosen.

• International Journal of Railway
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• v.7 no.3
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• pp.71-79
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• 2014

Subway systems have been a proved method of public transport and are widely used in major cities around the world. However, the time and cost it takes to construct such systems are very high, as it requires underground tunnels. Cities in various countries have implemented monorail systems as public railway transport as it can be more economical and quicker compared to subway systems in terms of construction. In addition, it provides more convenience towards the public as it is not affected to traffic, and also provides an aerial view of the city. However, the overall construction cost for monorail systems is still significantly high, and as a possible solution to further reduce the overall cost, implementation of ground-level stations and wireless power transfer technology has been proposed in this paper. A concept application layout of ground-level stations and wireless power transfer systems has been discussed, using the Daegu monorail Line 3 system as a simulation base. The expected cost for monorail systems implementing ground-level stations and/or wireless power transfer technology has been estimated based on literature survey, and was compared with the current construction cost of Daegu monorail system. Based on comparison, it has shown that implementation of ground-level stations are the most economical, and can be easily implemented for either starting or expanding the monorail line. Implementation of wireless power transfer technology is also economical, but is more feasible when starting a new monorail line as it requires components which will alter the configuration of the train and infrastructure.

• Earthquakes and Structures
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• v.11 no.6
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• pp.1101-1121
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• 2016

Base isolation, one of the popular seismic protection approaches proven to be effective in practical applications, has been widely applied worldwide during the past few decades. As the techniques mature, it has been recognised that, the biggest issue faced in base isolation technique is the challenge of great base displacement demand, which leads to the potential of overturning of the structure, instability and permanent damage of the isolators. Meanwhile, drain, ventilation and regular maintenance at the base isolation level are quite difficult and rather time- and fund- consuming, especially in the highly populated areas. To address these challenges, a number of efforts have been dedicated to propose new isolation systems, including segmental building, additional storey isolation (ASI) and mid-storey isolation system, etc. However, such techniques have their own flaws, among which whipping effect is the most obvious one. Moreover, due to their inherent passive nature, all these techniques, including traditional base isolation system, show incapability to cope with the unpredictable and diverse nature of earthquakes. The solution for the aforementioned challenge is to develop an innovative vibration isolation system to realise variable structural stiffness to maximise the adaptability and controllability of the system. Recently, advances on the development of an adaptive magneto-rheological elastomer (MRE) vibration isolator has enlightened the development of adaptive base isolation systems due to its ability to alter stiffness by changing applied electrical current. In this study, an innovative semi-active storey isolation system inserting such novel MRE isolators between each floor is proposed. The stiffness of each level in the proposed isolation system can thus be changed according to characteristics of the MRE isolators. Non-dominated sorting genetic algorithm type II (NSGA-II) with dynamic crowding distance (DCD) is utilised for the optimisation of the parameters at isolation level in the system. Extensive comparative simulation studies have been conducted using 5-storey benchmark model to evaluate the performance of the proposed isolation system under different earthquake excitations. Simulation results compare the seismic responses of bare building, building with passive controlled MRE base isolation system, building with passive-controlled MRE storey isolation system and building with optimised storey isolation system.

• BMB Reports
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• v.43 no.8
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• pp.567-572
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• 2010

In this study, we cloned the ERF-B3 subfamily transcription factor gene BnaERF-B3-hy15 from Brassica napus L. Huyou15. This 600 bp gene encodes a 199 amino acid classic ethylene responsive factor (ERF), which shown no binding or very weak binding GCC box-binding activity by the yeast one-hybrid assay. We used gene shuffling and the yeast one-hybrid system to obtain three mutated sequences that can bind to the GCC box. Sequence analysis indicated that two residues, Gly156 in the AP2 domain and Phe62 at the N-terminal domain were mutated to arginine and serine, respectively. Changes of Gly156 to arginine and Phe62 to serine increased the GCC-binding activity of BnaERF-B3-hy15 and the alter of Gly156 to arginine changed the AP2-domain structure of BnaERF-B3-hy15.

• YAKHAK HOEJI
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• v.40 no.4
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• pp.449-455
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• 1996

Betaine is one of the major water-soluble components in Lycii Fructus. In the present study the effect of repeated betaine treatment on the hepatotoxicity and the cytochrome P-4 50-dependent enzyme system was examined in adult female rats. Administrations of betaine (100 or 1,000mg/kg/day, ip) to rats repeatedly for 4 or 9 days did not evoke hepatotoxic response as determined by increases in glutamic pyruvic transaminase(GPT) and glutamic oxaloacetic transaminase(GOT) activities measured 24 hours following the final dose of betaine. The activities of aminopyrine N-demethylase, p-nitroanisole O-demethylase and p-nitrophenol hydroxylase as well as the contents of cytochrome P-450 were determined in hepatic microsomes of rats treated with betaine(1,000mg/kg/day, ip) for 4 or 9 days. Repeated treatment of rats with betaine for a period of 4 days induced a marginal decrease in the contents of cytochrome P-450, but did not influence the activities of p-nitrophenol hydroxylase, p-nitroanisole O-demethylase, or aminopyrine N-demethylase. Extension of the betaine treatment to 9 consecutive days failed to alter the parameters for hepatic drug metabolizing activity determined in the present study. Since repeated large doses of betaine were demonstrated to be tolerated by rats without showing any toxicity or changes in drug metabolizing enzyme activities in the liver, this compound appears to be relatively safe to animals upon long-term ingestion.

• Journal of Navigation and Port Research
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• v.32 no.6
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• pp.439-445
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• 2008

Various turning tests were carried out according to the rudder angle, turning direction, and the speed etc. with the ship's maneuverability measuring system on the training ship HANBADA. After that they were compared with each other on the turning circle, maneuvering performance index and the distance of new course, and then found out that they were satisfied with the IMO maneuvering standards. And the turning circles of port were smaller than those of starboard with all the rudder angles and maneuvering indexes such as K and T were relatively bigger than other vessels. Also, the distance cf new course was measured to $125{\sim}300m$ in case of the new course on $30^{\circ}{\sim}90^{\circ}$. All of these results will be helpful to escape from collision and to alter course on coastal voyage.