• Korean Journal of Air-Conditioning and Refrigeration Engineering
• /
• v.29 no.3
• /
• pp.134-141
• /
• 2017

The purpose of this study was to analyze physiological changes via a cold air reaction experiment to generate basic data that are useful for the development of an automobile active air conditioning system to prevent drowsiness. The $CO_2$ concentration causing drowsiness in vehicle operation was kept below a certain level. Air was blown to the driver's face by using an indoor air cooling apparatus. Sleepiness and the arousal state of the driver in cold wind were measured by physiological signals. It was evident in the EEG that alpha waves decreased and beta waves increased, caused by cold air stimulation. The ${\alpha}/{\beta}$ ratio was reduced by about 52.9% and an alert state confirmed. In the electrocardiogram analysis, the efficiency of cold air stimulation was confirmed by the mean heart rate interval change. The R-R interval had a delay time of about one minute compared to the EEG response. The findings confirmed an arousal effect from sleepiness due to cold air stimulation.

• Biomolecules & Therapeutics
• /
• v.7 no.3
• /
• pp.242-248
• /
• 1999

Diazepam, a benzodiazepine (BDZ) agonist, produces sedation and flumazenil, a BDZ antagonist, blocks these actions. The aim of this study was to examine the effects of BDZs on cortical electroencephalogram (EEG) in rats. The recording electrodes were implanted over the frontal and parietal cortices bilaterally, and the reference and ground electrodes over cerebellum under ketamine anesthesia. To assess the effects of diazepam and flumazenil, rats were injected with diazepam (1 mgHg, i.p.) and/or flumazenil ( 1 mg/kg, i.p.), and the EEG was recorded before and after drugs. Normal awake had theta peak in the spectrum and low amplitude waves, while normal sleep showed large amplitude of slow waves. The powers of delta, theta and alpha bands were increased during sleep compared with during awake. Diazepam reduced the mobility of the rat and induced sleep with intermittent fast spindles and large amplitude of slow activity, and it produced broad peak over betaL band and increased the power of gamma band, which were different from EEG patterns in normal sleep. Saline injection awakened rats and abolished fast spindles for a short period about 2-5 min from EEG pattern during diazepam-induced sleep. Flumazenil blocked both diazepam-induced sleep and decreased the slow activities of delta, theta, alpha and betaL, but not of gamma activity for about 10 min or more. This study may indicate that decrease in power of betaL and betaH bands can be used as the measure of central action of benzodiazepines, and that the EEG parameters of benzodiazepines have to be measured without control over the behavioral state by experimenter.

• The Journal of Korean Physical Therapy
• /
• v.33 no.2
• /
• pp.106-113
• /
• 2021

Purpose: This study examined the effectiveness of action observation training (AOT) and mirror therapy in improving the electroencephalograms (EEG) of stroke patients. Methods: Patients were allocated randomly to three groups: an action observation training with activity (AOTA) group (n=12), a mirror therapy with activity (MTA) group (n=11), and an AOT-only group (n=12). All groups received conventional physiotherapy in five 60-minute sessions over six weeks. The AOTA, MTA, and AOT groups practiced AOTA, MTA, and AOT, respectively, in three 30-minute sessions over six weeks. The differences between the pre- and post-treatment EEGs were assessed using a paired t-test. Comparisons between the groups were performed using one-way ANOVA. Results: The participants in the AOTA and MTA groups showed significant improvement in the EEG. AOTA improved the alpha waves of the prefrontal, temporal, and parietal lobes significantly (p<0.05). MTA improved the alpha waves of the temporal lobe significantly (p<0.05). AOT did not result in significant improvement Conclusion: AOTA and MTA improve stroke patients' EEGs. Mirror neuron activation combined with conventional stroke physiotherapy promotes motor recovery and functioning. The effect is enhanced when the actions are executed after observation. Further research into mirror neuron activation will be needed to develop methods to improve the EEGs of stroke patients.

• The Korean Journal of Physiology
• /
• v.27 no.2
• /
• pp.115-122
• /
• 1993

There is evidence that noradrenaline enhances spontaneous contractions dose-dependently in guinea-pig antral circular muscle. To investigate the mechanism of this excitatory action, slow waves and membrane currents were recorded using conventional microelectrode techniques in muscle strips and the whole cell patch clamp technique in isolated gastric myocytes. On recording slow waves, noradrenaline $(10^{-5}\;M)$ induced the hyperpolarization of the membrane potential, although the shape of the slow waves became tall and steep. Also, spike potentiaIs occurred at the peaks of slow waves. These changes were completely reversed by administration of phentolamine $(10^{-5}\;M),\;an\;{\alpha}-adrenoceptor$ blocker. Noradrenaline-induced hyperpolarization was blocked by apamin $(10^{-7}\;M)$, a blocker of a class of $Ca^{2+}\;-dependent\;K^+$ channels. To investigate the mechanisms for these effects, we performed whole cell patch clamp experiments. Norndrenaline increased voltage-dependent $Ca^{2+}$ currents in the whole range of test potentials. Noradrenaline also increased $Ca^{2+}\;-dependent\;K^+$\;currents, and this effects was abolished by apamin. These results suggest that the increase in amplitude and the generation of spike potentials on slow waves was caused by the activation of voltage-dependent $Ca^{2+}$ channel via adrenoceptors, and hyperpolarization of the membrane potential was mediated by activation of apamin-sensitive $Ca^{2+}\;-dependent\;K^+\;channels$.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.18 no.12
• /
• pp.459-465
• /
• 2017

This research aims to assess whether neurofeedback training can reduce theta waves in adolescents. The experiment was conducted on 35 early youths living in Gyeonggi-do at youth counseling centers during April-October. According to circumstances and opinions of participants in the pre-brain analysis, they were classified into a non-training group (A), 12-week training group (B), and 24-week training group (C), containing 10, 15, and 10 members, respectively. EEG measurement and neurofeedback training was performed using the prefrontal 2-channel NeuroharmonyS and Brain Optimization program. EEG data was processed utilizing Brain Analysis ver1.3. Deducted data was converted to SPSS 21.0 to enable statistical processing. As a strategy to reduce theta through the Beta increase training, we applied the appropriate Alpha, SMR, Beta low reward training to the individual. Study results confirmed that theta waves of adolescents decreased through the prefrontal neurofeedback training. Groups (B) and (C) exhibited a greater decrease in theta waves compared with the control group.

• Korean Journal of Occupational Health Nursing
• /
• v.29 no.2
• /
• pp.114-122
• /
• 2020

Purpose: This study aimed to identify the effect of integrated nursing using cognicise and neurofeedback on cognition and α waves among elderly individuals. Methods: This quasi-experimental single group pretest-posttest study included 29 Korean adults aged 65 years or older who participated at a senior welfare center in Y city from February to May 2019. Each integrated nursing session consisted of cognicise (10 minutes) and neurofeedback (20 minutes). Subjects participated twice a week for 10 weeks. Structured questionnaires to assess participants' general characteristics and the Korean version of the Mini-Mental Status Examination for Dementia Screening (K-MMSE-DS) were applied. Alpha waves were measured using BrainMaster. Results: Following the integrated nursing program, alpha waves improved in F3 (t=2.41, p=.023), C3 (t=3.00, p=.006), C4 (t=2.60, p=.015), P3 (t=2.43, p=.022), O1 (t=2.30, p=.029), T3 (t=3.05, p=.005), T4 (t=2.28, p=.030), T5 (t=2.91, p=.007), Fz (t=2.30, p=.029), Cz (t=2.73, p=.011), and Pz (t=2.23, p=.034). Most subjects experienced improvement in concentration after participating in the intervention. Conclusion: This study provides evidence for the use of a neuroscientific approach including brain wave measurement to improve cognitive health among community-living elderly people.

• Journal of The Korean Society of Integrative Medicine
• /
• v.7 no.3
• /
• pp.171-180
• /
• 2019

Purpose : The purpose of this study was to investigate the difference in motor cortical excitability during mental practice and action observation in subjects with forward head posture. Methods : This study was performed in two groups, a forward head posture group (n=17) and a normal posture group (n=17). Electroencephalography (EEG) was conducted to investigate cerebral cortex activity, and six electrodes were attached to Fp1, Fp2, C1, C2, C3, and C4 to measure the relative alpha power, relative beta power, relative gamma power, and mu rhythms. The subjects were requested to perform the four different conditions, which were eye opening, eye closing, mental practice, and action observation for 300 seconds. Results : The results showed that the relative alpha waves showed a significant difference between the normal and forward head posture groups in the C1, C2, C3, and C4 regions with the eyes open (p<.05). The relative beta waves also showed a significant difference between the two groups in the Fp1 and Fp2 regions during action observation (p<.05). The relative gamma waves were significantly different between the normal and forward head posture groups in the Fp1 and Fp2 regions during action observation (p<.05) in C1, C2, and C3 with eyes closed (p<.05) and in C1, C2, C3, and C4 with eyes open (p<.05). Conclusion : The results of this study showed that EEG change in the forward head posture group was different from that in the normal control group in action observation rather than in mental practice. Therefore, we are expected to provide a neurophysiological basis for applying action observation to motor skill learning during exercise for correcting forward head posture.

• Journal of The Korean Association For Science Education
• /
• v.21 no.3
• /
• pp.516-528
• /
• 2001

In the educational study, the measure of EEG(brain waves) can be useful method to study the functioning state of brain during learning behaviour. This study investigated the changes of neuronal response according to four times repetition of audio-visual learning. EEG data at the prefrontal$(Fp_{1},Fp_{2})$ were obtained from twenty subjects at the 8th grade, and analysed quantitatively using FFT(fast Fourier transform) program. The results were as follows: 1) In the first audio-visual learning, the activities of $\beta_{2}(20-30Hz)$ and $\beta_{1}(14-19Hz)$ waves increased highly, but the activities of $\theta(4-7Hz)$ and $\alpha$ (8-13Hz) waves decreased compared with the base lines. 2). According to the repetitive audio-visual learning, the activities of $\beta_{2}$ and $\beta_{1}$ waves decreased gradually after the 1st repetitive learning. And, the activity of $\beta_{2}$ wave had the higher change than that of $\beta_{1}$ wave. 3). The activity of $\alpha$ wave decreased smoothly according to the repetitive audio-visual learning, and the activity of $\theta$ wave decreased radically after twice repetitive learning. 4). $\beta$ and $\theta$ waves together showed high activities in the 2nd audio-visual learning(once repetition), and the learning achievement increased highly after the 2nd learning. 5). The right prefrontal$(Fp_{2})$ showed higher activation than the left$(Fp_{1})$ in the first audio-visual learning. However, there were not significant differences between the right and the left prefrontal EEG activities in the repetitive audio-visual learning. Based on these findings, we can conclude that the habituation of neuronal response shows up in the repetitive audio-visual learning and brain hemisphericity can be changed by learning experiences. In addition, it is suggested once repetition of audio-visual learning be effective on the improvement of the learning achievement and on the activation of the brain function.

• Journal of the Korean Society of Safety
• /
• v.26 no.3
• /
• pp.83-90
• /
• 2011

It is well known that urgency resulted from time stress can be a great cause to industrial accidents. Therefore, time stress has been studied in the aspect of macroscopic view, namely industrial safety management, but has not been studied in microscopic view such as psychophysiological approach. Among diverse psychophysiological indices, Electroencephalogram(EEG) would be on of the most objective psychophysiological research technique on human errors though few research has been taken yet. This study aimed to get characteristics of human error while committing a simple arithmetic addition task by utilizing the power spectrum technique of EEG data. Each experiment was composed of 2 tasks under different condition - with and without time stress. As subjects, 5 young undergraduate students in their early twenties participated in this study. The results advocated a well-known fact that time stress downgrades the performance of human workers. However, correct answer rate and response time were not significantly influenced by time stress factor which might be explained by the constructural factor adopted in the present study. As in the previous studies, among various EEG-related measures, relative band power ratios of ${\alpha}$ and ${\beta}$ waves to sum of ${\alpha}$,${\beta}$,${\theta}$ wave powers, namely $P_{{\alpha}/({\alpha}+{\beta}+{\theta})}$ and $P_{{\beta}/({\alpha}+{\beta}+{\theta})}$ seemed to be the most effective measures to grasp variation of brain activities in time-stressed situation so that discussions were expanded about their variations.

• Journal of Biomedical Engineering Research
• /
• v.37 no.3
• /
• pp.119-125
• /
• 2016

Sexual addiction is accompanied with anxiety, psychological and physical dependence. Also, sexual addict want to make their presence through sexual adventures and seem sexually obsessed. In this study, we examined the changes of brain activity related to sexual addiction by utilizing the developed multi-sensory therapy after 4-weeks sex offender treatment program. We analyzed the electroencephalogram (EEG) activity changes in the subjects and regions of brain. As a result, the theta wave significantly increased after treatment than before (p < 0.001). The absolute alpha wave was increased whereas the relative alpha waves were decrease significantly (p < 0.001). The results could conclude that multi-sensory therapy on sex offender shows more stable status against sexual stimulations. Moreover, the reduction of the relative alpha waves in parietal lobe of sex offender is correlated to the less attention on sexual stimulations. The multi-sensory therapy not only provides a neurobiological explanation, but also can be used for clinical implications, i.e. prevention and treatments, for sex addiction.