• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.31 no.2
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• pp.123-132
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• 2018

Objectives : The purpose of this report is to know the effect of Korean medicine treatments on Allergic Contact Dermatitis. Methods : We treated a 63-years-old man patient with Allergic Contact Dermatitis on the left medial calf with Korean medicine. After Korean medical treatment for 26 days, we identified a reduction in size of erythema and loss of color fading, exudates and edema. We recorded pictures of changes on symptoms. Results & Conclusions : The symptoms of Allergic Contact Dermatitis were improved. Erythema, edema, exudate were lost. Thus Korean medicine treatments are effective on allergic contact dermatitis.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.29 no.4
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• pp.78-94
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• 2016

Objectives : This study was carried out to analyze the trends of clinical studies of allergic contact dermatitis published in the Journal of Korean Medical Ophthalmology & Otolaryngology & Dermatology. Methods : We studied 10 research papers on allergic contact dermatitis published in JKOOD. We analyzed about experiment methods, pharmacodynamic effects, therapeutic effects in published papers. Results : 1. The number of searched journal is 10 papers. 2. All experiments was performed using DNCB primed mouse. To demonstrate therapeutic effect of drugs, previous researches observed dermatological and histopathogical conditions, erythema, melasma, white blood cell count, Lymphocyte ratio to white blood cell. 3. Most of drugs have heat-clearing and detoxifying effects. 4. Every drugs have positive effect in treating allergic contact dermatitis. Conclusions : Figuring out how experiment proceeded and tendency of drugs in researching allergic contact dermatitis is significance of this paper. Further research about drugs and their treating methods should be carried out to improve curative effectiveness for allergic contact dermatitis.

• Korean journal of dermatology
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• v.56 no.10
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• pp.624-627
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• 2018

Allergic contact dermatitis is an inflammatory condition associated with periorbital erythema, edema, and pruritus. The periorbital skin is relatively thin compared with the skin over other facial areas; therefore, it is vulnerable to allergen penetration and may show a variety of cutaneous manifestations. Recently, vision enhancement surgery is a widely performed procedure, and the prevalence of senile cataract and glaucoma is increasing. The prevalence of periocular allergic contact dermatitis is increasing secondary to the growing use of topical ophthalmic medications. Several studies in Korea have reported periocular allergic contact dermatitis secondary to the use of topical ophthalmic medications including latanoprost ($Latano^{(R)}$), fluorometholone ($Tolon^{(R)}$), polymyxin B ($Terramycin^{(R)}$), atropine sulfate ($Atropine^{(R)}$), neomycin sulfate ($Cambison^{(R)}$), and befunolol hydrochloride ($Bentos^{(R)}$), among others. However, ofloxacin ($Effexin^{(R)})$-induced allergic contact dermatitis has not been reported in the domestic and/or foreign literature. We report a case of periocular allergic contact dermatitis secondary to the use of ofloxacin ophthalmic ointment.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.31 no.3
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• pp.107-115
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• 2018

Objectives : The purpose of this paper is to report the effect of Korean medicine treatments on allergic contact dermatitis aggravated after applying steroid ointment. Methods : We treated a 63-year-old woman with allergic contact dermatitis on the both forearm, jaw, neck, chest with Korean medicine. Before Korean medicine treatments she has taken oral steroids and applied steroid ointment for several years to treat dermatitis, but long-tern steroid therapy aggravated her symptoms like skin pruritus, erythema, exudates or edema. After Korean medical treatment for 27 days, we found that the size of erythema was reduced, and symptoms like pruritus, exudates and edema were lost. We recorded pictures of changes on symptoms. Results & Conclusions : The symptoms of allergic contact dermatitis were improved. Erythema, edema, exudate were lost. Thus Korean medicine treatments are effective on allergic contact dermatitis and could be a great alternative to steroid treatment.

• 대한상한금궤의학회지
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• v.13 no.1
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• pp.121-132
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• 2021

Objective: This study aimed to report the improvement in a patient with allergic contact dermatitis treated with Sihogyeji-tang based on the Shanghanlun disease pattern identification diagnostic system (DPIDS). Methods: According to the Shanghanlun DPIDS, the patient with allergic contact dermatitis was diagnosed with greater yang disease chest bind (Shanghanlun provision 146), and was administered Sihogyeji-tang for 90 days. The results were evaluated using the Dermatological Life Quality Index (DLQI) and a visual analog scale (VAS). Results: After taking Sihogyeji-tang for 90 days, the DLQI decreased from 28 points to 8 points and the VAS decreased from 10 points to 3 points. Conclusions: This case shows the potential of treatment through herbal medicine for allergic contact dermatitis using the Shanghanlun DPIDS.

• Biomedical Science Letters
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• v.17 no.1
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• pp.47-53
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• 2011

This study is aimed to investigate the skin thickness, plasma components, serum IgE level and antioxidant enzymes activities by mixtures of Cnidium officinale, Saururus chinensis, Houttuynia cordata and Glycyrrhiza uralensis on the allergic contact dermatitis of rat induced by 1-chloro-2,4-dinitrochlorobenzene (DNCB). Mixtures reduced the thickness of the skin and removed the dead skin cells compared to the skin of rats treated with DNCB alone. Also, these mixtures down-regulated the contents of lipid and IgE, and reduced the activities of superoxide dismutase and catalase. These results indicate that the mixtures significantly recovered the contact dermatitis induced by DNCB. In conclusion, it is thought that the mixtures could be useful for the allergic contact dermatitis.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.18 no.3
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• pp.44-54
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• 2005

Background and Objectives: Allergic contact dermatitis is a common environmental health issue and seriously affect the patient's quality of life. The more our environment industrialized, the number of material that could cause the allergic contact dermatitis has been increased, consequently the prevalence of allergic contact dermatitis has been increased. In oriental medicine, clinically Chogam-Tang has been used fur the treatment of allergic dermatitis, eczema, atopic dermatitis etc. The objective of this study is to investigate the effects of Chogam-Tang on allergic contact dermatitis Meterial and Methods: Fifteen Sprague-Dawley rats were divided into three groups: normal, control, experimental group. Control and experimental group were induced allergic contact dermatitis, by DNCB. Experimental group was orally administered the Chogam-Tang. Each group was observed after 24, 48 and 72 hours. Contact hypersensitivity assay, melanin-erythema measurement, pH measurement skin moisture measurement and biopsy were performed. Results: 1. In contact hypersensitivity assay, experimental group showed decreased ear swelling compared with control group at 48hours. 2. ln melanin measurement there was no difference in three groups. 3. In erythema measurement experimental group showed reduction at 48. 72 hours. 4. In pH measurement, experimental group and control group showed increase in pH but there was no statistical significance. 5. In skin moisture measurement, experimental group showed higher skin moisture level than control group at 24 hours and showed lower skin moisture level at 72 hours, but there was no statistical significance. 6. In biopsy, experimental group showed decrement of Iymphocyte as time goes by, and regeneration of keratin layer was increased compared with normal group. Conclusions: Chogam-Tang shows anti-inflammatory effect in biopsy, improves hydration levels of skin, decreases erythema level on allergic contact dermatitis.

• Journal of Haehwa Medicine
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• v.20 no.2
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• pp.125-131
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• 2012

The number of allergic contact dermatitis patients is steadily increasing but a proper reliability treatment guide is not prepared in Oriental Medicine. Also, the number of clinical cases on allergic contact dermatitis is not sufficient in Oriental medicine. As such, the facial flushing of allergic contact dermatitis which has been improved by infra-red therapy is significant in its treatment purpose. We reported on 43-year old male patient with allergic contact dermatitis. We treated him with herbal concoction, acupuncture, infra-red therapy and cupping therapy. We have received a good result in this case by using the combination of infra-red therapy. We reached a conclusion that using infra-red therapy can improve the facial flushing of patient with allergic contact dermatitis. However, further research on the effect of infra-red therapy for these symptoms is desired.

• Journal of Sasang Constitutional Medicine
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• v.13 no.3
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• pp.89-101
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• 2001

1. The purpose of study To study the effectiveness of Yangkyuksanhawtang(YST) against Allergic Contact Dermatitis(ACD) I observed the change of cutaneous shape, histochemistry, immunohistochemistry, and the distribution of apoptotic cells. 2. The material and method of study I divided 4-month-old rats into three groups of 10, which are a contrastive group of having applied Acetone olive oil only, ACD group to have intentionally activated Allergic Contact Dermatitis by DNCB and YST group to give medication of Yangkyuksanhawtang extract. And I observed each group of mice after 24, 48 and 72 hours. 3. The result and conclusion of study The change of cutaneous shape and hypersensitive reaction of immunity was significantly decreased by YST in ACD rats. I consider that YST suppressed hypersensitive reaction of immunity and inflammation in ACD.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.27 no.4
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• pp.209-220
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• 2014

Objectives : The purpose of this study is to report the effect of Korean medicine treatment on occupational allergic contact dermatitis caused by mortar. Methods : The patient treated by herbal medicine, acupuncture, pharmacopuncture and external therapy. The progress is evaluated by Numerical Rating Scale(NRS) and Dermatology Life Quality Index(DLQI). Results : NRS and DLQI score were significantly decreased as a result of Korean medicine treatment. Conclusions : Korean medicine treatment should be effective for the occupational allergic contact dermatitis caused by mortar. More studies are needed to confirm stability of these treatment.