• Title/Summary/Keyword: Alkaloids

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Antifungal Activity of Chaerophylline and Berberine Hydroxide Isolated from Corydalis Species

  • Tuli, Leepika;Jha, R.N.;Pandey, V.B.;Singh, U.P.
    • Mycobiology
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    • v.29 no.2
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    • pp.100-103
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    • 2001
  • Chaerophylline and berberine hydroxide, both being alkaloids, isolated from Corydalis chaerophylla and C. longipes respectively were assayed against spore germination of some fungi, e.g. Alternaria solani, A. brassicola, A. brassicicola, Helminthosporium penniseti, Helminthosporium sp., Heterosporium sp., Curvularia penniseti, C. maculens and C. palliscens. While chaerophylline inhibited spore germination of most of the fungi at 1000 ppm, being also effective at 50, 100, 200 and 500 ppm, berberine hydroxide was significantly effective at much lower concentration, i.e., 400 ppm against several fungi. This compound was also effective against some fungi at 50, 100, 150, 200 ppm. There was 100% inhibition of spore germination in several fungi at highest concentration of both the compounds. Some of the fungi showed similar results even at lower concentrations.

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Phytochemical Screening of Korean Medicinal Plants I

  • Woo, Won-Sick;Chi, Hyung-Joon;Yun, Hey-Sook;Woo, Lin-Keun
    • YAKHAK HOEJI
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    • v.20 no.3
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    • pp.138-144
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    • 1976
  • In previous communications$^{1-6)}$, the results of the preliminary phytochemical examinatioins of 261 plant samples which have been used in medicine in Korea were reported. In continuation of this program we now present in Table I the results of chemical examination of another 92 species, belonging to 80 genera nad 48 families, which were screened for the presence of alkaloids, saponins, terpenoids, and flavonoids. The list of folk medicines described by Lee$^{7)}$ was used as a guide in the selection of plants to be tested.

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Precursor Feeding Effects of Alkaloid Production in Suspension Cultures of Eschscholtzia californica (캘리포니아 양귀비(Eschscholtzia californica) 현탁세포배양에서 전구체가 알칼로이드 생성에 미치는 영향)

  • 주영운;김철변상요
    • KSBB Journal
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    • v.8 no.5
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    • pp.488-494
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    • 1993
  • The accumulation of benzophenanthridine alkaloids, sanguinarine, chelerythrine, chelirubine and macarpine occurred in suspension cultures of Eschscholtzia californica. To increase alkaloid production, feeding experiments with the biosynthetic precursors, tyrosine, tyramine, L-dopa, dopamine with and without elicitation were studied. In feeding experiments with various precursors, the total alkaloid production was slightly increased. The precursor feeding with elicitation, however, increased total alkaloid production several times.

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Current Status and Prospect of Antiobesity Functional Agents

  • Do Myoung-Sool
    • Proceedings of the Korean Society of Food Science and Nutrition Conference
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    • 2004.11a
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    • pp.103-109
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    • 2004
  • The obese population has been increasing over the world wide and obesity became a socioeconomic problems. It is become more serious by the accumulation of the knowledge that the obesity is related directly or indirectly with several diseases like, diabetes, hypertension, etc. With these reasons, many functional food or agents for the purpose of weight loss have been developed. However, most of these remedies are unproven and some have produced even dangerous side effects due to the ephedrine alkaloids contained in Ma-Hang. Because of these reasons, they banned using of these agents in US and regards the antiobesity functional agents as drugs in Europe. Several functional agents are known for weight loss activities like, HCA, L-canitine, CLA, chitosan, calcium supplements and capsaicin containing red pepper, kimchi and kochujang. We describe here about the function, efficacy and mechanism of these antiobesity functional agents. Furthermore, the trial of the mixture of weight loss related herbal ingredients for safe multifunctional antiobesity functional agents are discussed here, as well.

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A study on Caffeine containing foods and the effect of caffeine in humans (카페인이 인체에 미치는 영향 및 섭취량 감소 방안에 관한 연구)

  • 이혜원
    • Culinary science and hospitality research
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    • v.6 no.3
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    • pp.343-355
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    • 2000
  • Caffeine is widely consumed ingredient and it belongs to alkaloids. Many foods that we intake contain caffeine ; coffee, tea cocoa, chocolate, and coke. And it is also added to many commercial remedies ; cold tablets, headache tablets, etc. Effect of caffeine that is known to us so far is as follows; 1. Remaining awake for long hours 2. Increasing concentration and decreasing fatigue 3. Increasing basal metabolic rate 4. decomposing glycogen and body fat and providing energy 5. Stimulating gastric acid 6. Increasing urinary excretion. Caffeine containing beverages(especially, coffee)are also favorite food in adult. In case of children and youth, chocolate and coke are favorite food. So, to intake caffeine containing foods moderately can be a vitality of life. But, a long-term intake or overdose of caffeine can result in many side effects. For example, headache, irritability, restlessness, hypertension, fetal abnormality, etc. Therefore, it is desirable that caffeine intake is under 300-400mg per day. To decrease intake of caffeine, 1. Use decaffeinated coffee 2. Product of decaffeinated coffee bean through gene transformation 3. Indicate content and function of caffeine on caffeine-food container 4. Provide an information of caffeine to public.

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Separation and Activity Test of Antifungal Substance from C. japonica Extract (황련 추출물로부터 항균활성물질의 분리 및 활성 검정)

  • Chung, Ill-Min;Paik, Su-Bong
    • Analytical Science and Technology
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    • v.10 no.2
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    • pp.153-159
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    • 1997
  • This study was conducted to test antifungal activity and to separate bioactive compound using C. japonica extract which was shown the most effective control on the B. berengeriana, G. cingulata and P. expansum. $EC_{50}$ on the test pathogene of C. japonica extract was $400{\sim}500{\mu}g/mL$. Bioactive compound analyzed by TLC and HPLC method was identified as a kind of alkaloids, berberine, and the content was 81.14%.

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The Effect of Light on the Production of Reserpine in Cultured Rauwolfia serpentina Cells

  • Yamamoto, Osamu
    • Natural Product Sciences
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    • v.2 no.2
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    • pp.90-95
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    • 1996
  • When reserpine-producing cell strains of Rauwolfia serpentina were transferred from the dark to the light irradiation, the production of reserpine was extremely enhanced whereas the cell growth was suppressed. In an incubation period of 20 days, the most effective culture condition for reserpine production was the combination of 8 days of dark culture and following 12 days of light culture. The time courses of both cell growth and reserpine production were measured in vitro in order to clarify the effect of wave length range of light on the biosynthesis of reserpine. Although the growth of cultured cells which had been incubated under continuous red, yellow, and green lights, respectively, was similar to that of the cultured cells subcultured in the dark. The cells cultured under red light irradiation produced less reserpine than dark-grown cultures. Both blue and near-ultraviolet light inhibited the growth of cultured cells. The production of reserpine was strikingly enhanced by blue light, but was strongly inhibited by near-ultraviolet light.

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