• Title/Summary/Keyword: Alkaloids

검색결과 488건 처리시간 0.024초

Bioactive Constituents of Marine Sponges of the Genus Spongosorites

  • Bao, Baoquan;Hong, Jongki;Lee, Chong-O.;Cho, Hee Young;Jung, Jee H.
    • 한국해양바이오학회지
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    • 제1권3호
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    • pp.144-155
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    • 2006
  • This report reviews the literatures on chemical constituents of marine sponges of the genus Spongosorites and also highlights our own research. Specific biological activities of the metabolites from these sponges include: cytotoxic, antitumor, antibacterial, antifungal, antiviral, anti-inflammatory, and other pharmacological activities.

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Alkaloids are the sedative principles of the seeds of zizyphus vulgaris var spinosus

  • Han, Byung-Hoon;Park, Myung-Hwan
    • Archives of Pharmacal Research
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    • 제10권4호
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    • pp.203-207
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    • 1987
  • Sedative principles of the seeds of Zizyphus vulgaris var. sphinosus have been characterized as sanjoinine-A (frangufoline), nuciferine and their congeners. Also, heat treatment of sanjoinine-A-produced a more active artifact, sanjoinine-Ahl, which provides a scientific basis for heat-processing (roasting) of this Oriental medicine.

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Total Synthesis of ($\pm$)-Homoepibatidine

  • Kim, Yong-Hyun;Won, Do-Youn;Oh, Chang-Young;Lee, Kee-Young;Jeong, Jin-Hyun;Jung, Young-Hoon;Ham, Won-Hun
    • Archives of Pharmacal Research
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    • 제22권4호
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    • pp.435-436
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    • 1999
  • Total synthesis of ($\pm$)-homoepibatidine (2), which contains the 8-azabicyclo[3.2.1] octane ring system, was achieved by using palladium-catalyzed Heck-type coupling reaction from 3.

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Novel Synthesis of the Natural Protoberberine Alkaloids: Oxypalmatine and Oxypseudopalmatine

  • Le, Thanh Nguyen;Cho, Won-Jea
    • Bulletin of the Korean Chemical Society
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    • 제28권5호
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    • pp.763-766
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    • 2007
  • Oxypalmatine and oxypseudopalmatine were synthesized in three steps from the benzonitrile 11 and toluamides 12a, b. The lithiated cycloaddition reaction yielded 3-arylisoquinolinone intermediates. A subsequent internal SN2 reaction produced the corresponding 8-oxoprotoberberines, oxypalmatine and oxypseudopalmatine.

An Expedient Synthesis of Oxindole Dimers by Direct Oxidative Dimerization of Oxindoles

  • Lee, Hyun Ju;Lee, Sangku;Lim, Jin Woo;Kim, Jae Nyoung
    • Bulletin of the Korean Chemical Society
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    • 제34권8호
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    • pp.2446-2450
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    • 2013
  • Oxindole dimers have been used as intermediates in the synthesis of various cyclotryptamine alkaloids. An efficient direct synthesis of oxindole dimers has been carried out from 3-substituted oxindoles via an oxidative dimerization using manganese(III) acetate or copper acetate/silver acetate system.

Piperoctadecalindine, a New Piperidine Alkaloid from Piper retrofractum Fruits

  • Ahn Jong Woong;Lee Chong Ock;Kim Eun Joo;Zee Ok Pyo;Kim Hyung Jin
    • Bulletin of the Korean Chemical Society
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    • 제13권4호
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    • pp.388-391
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    • 1992
  • A chemical investigation of the fruits of Piper retrofractum (Piperaceae) has led to the isolation and characterization of a novel piperidine alkaloid, piperoctadecalidine together with three known alkaloids piperine, pipernonaline and guineensine. The structure of the new compound was detemined to be (2E,4E,14Z)-N-(2,4,14-Octadecatrienoyl) piperidine by spectral and synthetic methods.