• Title/Summary/Keyword: Alignment-based design

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A Physical Data Design and Query Routing Technique of High Performance BLAST on E-Cluster (고성능 BLAST구현을 위한 E-Cluster 기반 데이터 분할 및 질의 라우팅 기법)

  • Kim, Tae-Kyung;Cho, Wan-Sup
    • Journal of the Korea Society of Computer and Information
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    • v.14 no.2
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    • pp.139-147
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    • 2009
  • BLAST (Basic Local Alignment Search Tool) is a best well-known tool in a bioinformatics area. BLAST quickly compares input sequences with annotated huge sequence databases and predicts their functions. It helps biologists to make it easy to annotate newly found sequences with reduced experimental time, scope, and cost. However, as the amount of sequences is increasing remarkably with the advance of sequencing machines, performance of BLAST has been a critical issue and tried to solve it with several alternatives. In this paper, we propose a new PC-Based Cluster system (E-Cluster), a new physical data design methodology (logical partitioning technique) and a query routing technique (intra-query routing). To verify our system, we measure response time, speedup, and efficiency for various sizes of sequences in NR (Non-Redundancy) database. Experimental result shows that proposed system has better speedup and efficiency (maximum 600%) than those o( conventional approaches such as SMF machines, clusters, and grids.

Introducing a New Pedagogical Approach for Ergonomic Pattern Education: Leveraging a Half-Scale Body Form Based on 3D Modeling (인체공학적 패턴 교육을 위한 새로운 교수법 제안: 3D 모델링 기반으로 제작한 Half Scale Body Form를 이용하여)

  • Lin Chen;Yuhwa Hong;Juyeon Park
    • Fashion & Textile Research Journal
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    • v.26 no.1
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    • pp.78-87
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    • 2024
  • This study aimed to propose an innovative teaching pedagogy using a half-scale body form in apparel design education and evaluate its effectiveness in augmenting students' understanding of ergonomic patterns. Constructed in alignment with Phoenix's (2018) study, which used 3D body scanning and digital editing software, the half-scale body form was created through a five-step process, encompassing body measurement, 3D body modeling, fabrication of a physical half-scale body form, pattern making, and evaluation. Implemented in an undergraduate patternmaking course offered at a 4-year university in the metropolitan Seoul, this instructional approach's effectiveness was gauged through students' course projects and exit interviews. The results underscored the positive impact of the proposed teaching pedagogy on students' grasp of ergonomic pattern development, fostering a keen understanding of diverse body shapes and sizes and the relationship between the human body and garments. Furthermore, it played a role in cultivating positive body image and self-endorsement among students. The research contributes meaningfully by presenting a fresh perspective in apparel design education, seamlessly integrating advanced anthropometric and technological tools into a conventional patternmaking classroom. It offers a novel learning experience for students majoring in apparel, creating a fun and interactive teaching environment.

Forecasting and Analysis of Customized Shoes Design in Domestic and Overseas Brands (국내외 커스텀 슈즈 디자인 현황 및 전망)

  • Byun, Hee Jean;Byun, Trina Hyunjin
    • The Journal of the Korea Contents Association
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    • v.16 no.1
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    • pp.382-390
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    • 2016
  • This study has investigated the status and overview of design characteristics of customized shoes, which receives much recognition at domestic and overseas markets. Based on the market research on current consumer lifestyle and needs of the custom-shoes(which is an abbreviation of customized shoes), this study has provided its development directions, views and demands. The design types of custom-shoes have been broadly divide into two: firstly 'style centered custom-shoes'; secondly 'function centered custom-shoes'. Style centered custom-shoes are specifically divided into 3 types; first, formal custom-shoes; second, sports and casual custom-shoes; and lastly, bespoke shoes. Function centered custom-shoes design refers to enhancing the function of personal soleprint which has to be designed by delicately detailed insole and outsole, rather than alignment of exterior parts of the shoes. These are used in professional sports shoes and also include orthopedics footwear and grafted footwear for people who have disabled on foot. Custom footwear market has been highly expanded and has entered value-added market according to increasing interest in foot health and shopping trends on shoes buying like taking shoes as personal expression in accordance with a variety of places and situations. In the near future, custom-shoes can be produced in a couple of days due to the technological advance of 3D scanners and 3D printers. This phenomenon will wants more demands of specific shoes experts such as custom-design consultants or shoes fitting experts, who can overcome limitations of online custom-shoes stores.

Application of GIS Based AHP for Route Location (노선 선정에서 계층분석과정을 이용한 GIS의 적용)

  • Roh, Tae Ho;Jeong, In Ju;Lee, Sung Rock
    • Journal of the Korean Association of Geographic Information Studies
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    • v.8 no.2
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    • pp.55-67
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    • 2005
  • This study presented the route location method by applying AHP and evaluating quantitatively. This study developed the program that can be easily applied to this kind of road design, and built the decision support system for route location. The study results are summarized as follows ; We could quantitatively evaluate the appropriateness of exiting routes by applying the AHP based on GIS. If we apply this to the roads that will be newly constructed, we can make the objective and reliable route location when making road plans and basic designs. We improved the technique of route location by applying the decision support system with third-dimensional data, which considers even the vertical alignment plan, to the existing decision support system with second-dimensional data. And, since we can set those data such as vertical slope, earth-volume, structure size, location and construction cost to independent variables, we can make road designs more scientifically and reasonably.

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Multi-sensor Fusion Based Guidance and Navigation System Design of Autonomous Mine Disposal System Using Finite State Machine (유한 상태 기계를 이용한 자율무인기뢰처리기의 다중센서융합기반 수중유도항법시스템 설계)

  • Kim, Ki-Hun;Choi, Hyun-Taek;Lee, Chong-Moo
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.47 no.6
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    • pp.33-42
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    • 2010
  • This research propose a practical guidance system considering ocean currents in real sea operation. Optimality of generated path is not an issue in this paper. Way-points from start point to possible goal positions are selected by experienced human supervisors considering major ocean current axis. This paper also describes the implementation of a precise underwater navigation solution using multi-sensor fusion technique based on USBL, GPS, DVL and AHRS measurements in detail. To implement the precise, accurate and frequent underwater navigation solution, three strategies are chosen. The first one is the heading alignment angle identification to enhance the performance of standalone dead-reckoning algorithm. The second one is that absolute position is fused timely to prevent accumulation of integration error, where the absolute position can be selected between USBL and GPS considering sensor status. The third one is introduction of effective outlier rejection algorithm. The performance of the developed algorithm is verified with experimental data of mine disposal vehicle and deep-sea ROV.

A New Confidence Measure for Eye Detection Using Pixel Selection (눈 검출에서의 픽셀 선택을 이용한 신뢰 척도)

  • Lee, Yonggeol;Choi, Sang-Il
    • KIPS Transactions on Software and Data Engineering
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    • v.4 no.7
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    • pp.291-296
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    • 2015
  • In this paper, we propose a new confidence measure using pixel selection for eye detection and design a hybrid eye detector. For this, we produce sub-images by applying a pixel selection method to the eye patches and construct the BDA(Biased Discriminant Analysis) feature space for measuring the confidence of the eye detection results. For a hybrid eye detector, we select HFED(Haar-like Feature based Eye Detector) and MFED(MCT Feature based Eye Detector), which are complementary to each other, as basic detectors. For a given image, each basic detector conducts eye detection and the confidence of each result is estimated in the BDA feature space by calculating the distances between the produced eye patches and the mean of positive samples in the training set. Then, the result with higher confidence is adopted as the final eye detection result and is used to the face alignment process for face recognition. The experimental results for various face databases show that the proposed method performs more accurate eye detection and consequently results in better face recognition performance compared with other methods.

QM and Pharmacophore based 3D-QSAR of MK886 Analogues against mPGES-1

  • Pasha, F.A.;Muddassar, M.;Jung, Hwan-Won;Yang, Beom-Seok;Lee, Cheol-Ju;Oh, Jung-Soo;Cho, Seung-Joo;Cho, Hoon
    • Bulletin of the Korean Chemical Society
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    • v.29 no.3
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    • pp.647-655
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    • 2008
  • Microsomal prostaglandin E2 synthase (mPGES-1) is a potent target for pain and inflammation. Various QSAR (quantitative structure activity relationship) analyses used to understand the factors affecting inhibitory potency for a series of MK886 analogues. We derived four QSAR models utilizing various quantum mechanical (QM) descriptors. These QM models indicate that steric, electrostatic and hydrophobic interaction can be important factors. Common pharmacophore hypotheses (CPHs) also have studied. The QSAR model derived by best-fitted CPHs considering hydrophobic, negative group and ring effect gave a reasonable result (q2 = 0.77, r2 = 0.97 and Rtestset = 0.90). The pharmacophore-derived molecular alignment subsequently used for 3D-QSAR. The CoMFA (Comparative Molecular Field Analysis) and CoMSIA (Comparative Molecular Similarity Indices Analysis) techniques employed on same series of mPGES-1 inhibitors which gives a statistically reasonable result (CoMFA; q2 = 0.90, r2 = 0.99. CoMSIA; q2 = 0.93, r2 = 1.00). All modeling results (QM-based QSAR, pharmacophore modeling and 3D-QSAR) imply steric, electrostatic and hydrophobic contribution to the inhibitory activity. CoMFA and CoMSIA models suggest the introduction of bulky group around ring B may enhance the inhibitory activity.

Image Exposure Compensation Based on Conditional Expectation (Conditional Expectation을 이용한 영상의 노출 보정)

  • Kim, Dong-Sik;Lee, Su-Yeon
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.42 no.6
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    • pp.121-132
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    • 2005
  • In the formation of images in a camera, the exposure time is appropriately adjusted to obtain a good image. Hence for a successful alignment of a sequence of images to the same scene, it is required to compensate the different exposure times. If we have no knowledge regarding the exposure time, then we should develop an algorithm that can compensate an image with respect to a reference image without using any camera formation models. In this paper, an exposure compensation is performed by designing predictors based on the conditional expectation between the reference and input images. Further, an adaptive predictor design is conducted to manage the irregular exposure or histogram problem. In order to alleviate the blocking artifact and the overfitting problems in the adaptive scheme, a smoothing technique, which uses the pixels of the adjacent blocks, is proposed. We successfully conducted the exposure compensation using real images obtained from digital cameras and the transmission electron microscopy.

A Research Review on Effective Use of IS drawn on Multi-level Dynamic Capability (정보시스템 분석수준 별 역동적 역량에 기반한 효율적 사용에 관한 연구 리뷰)

  • Kang, Hyunjeong
    • The Journal of Information Systems
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    • v.29 no.2
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    • pp.27-50
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    • 2020
  • Purpose The research on the effective use of IS needs to embrace the alignment to organization learning process, which expands the limited focus on dynamic capability of IS use. In addition, it should be done in multi-level analysis with system, user, task, and organization. The current study suggests the inclusion of multi-level analysis of effective use of IS in the perspective of exploration and exploitation. Design/methodology/approach This review selected the representative studies in IS discipline which have investigated the effective use of IS, dynamic capability, operational capability, exploration, exploitation, or organizational learning. In the search of academic archives with those keywords, seventeen papers which have been most cited were chosen and validated whether the focus constructs are directly theorized or validated the suggested keywords. In addition, the level of analysis was verified whether it includes one or more levels of system, individual, task, or organization. Based on the initial analysis of dynamic capability, the further review of research on explorational and exploitational capabilities was implemented. Findings The present review study on previous literature on effective use of IS presented that it is largely implemented in the level of individual but few of them has included organization level. Similarly, the direct investigation of explorational and exploitational use of IS has not been done so much. The needs of study on effective use of IS in depth have been inquired for a decade. However, the review presented that it still lacks profound theories and empirical validations compared to those of adoption stage of IS. Based on the review, future research on the transition between explorational and exploitational use of IS is suggested.

Robotic Surgery in the Orthopedic Field (정형외과 영역에서 로봇수술)

  • Lee, Woo-Suk;Jung, Woo-Suk
    • Journal of the Korean Orthopaedic Association
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    • v.53 no.6
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    • pp.459-465
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    • 2018
  • Of the many factors that affect the clinical outcomes of orthopedic surgery, the surgical procedure is the most important. Robotics have been developed to perform the surgical procedures more accurately and consistently. Robotic surgical procedures in the orthopedic field were developed 20 years ago. Some designs of surgical robots have disappeared due to practical problems and complications, and an another design of surgical robots is emerging. To date, the use of robot surgery in arthroplasty is still controversial in terms of the clinical outcomes, practicality, and cost-effectiveness, even though it has been reported to be effective in the alignment and positioning of components in the field of artificial joints. Early robotic surgery was based mainly on active robot surgery according to the scheduled operation without the intervention of the operator. Recently the semi-active system of robotic surgery has been introduced. In a semi-active system, the robot constrains the surgeon to a haptic boundary defined by the computer based on the 3-dimensional imaging preoperative plan, and the operator can change the preoperative plan through real-time feedback during operation.