• Title/Summary/Keyword: Alcohol Accumulate

Search Result 3, Processing Time 0.017 seconds

A Correlation Analysis between Alcohol Accumulate and Liver Function State through Color Change Analysis of the Left Cheek and White Eyes (왼뺨 및 흰 눈동자 색상 변화 분석을 통한 알코올 누적과 간 기능 상태와의 상관성 분석)

  • Kim, Bong-Hyun;Cho, Dong-Uk
    • The Journal of Korean Institute of Communications and Information Sciences
    • /
    • v.36 no.8B
    • /
    • pp.971-978
    • /
    • 2011
  • There is a method to judge state of organs by looking color and shape of face in diagnosis of Oriental Medicine, So, to diagnosis of health condition has been applied development medical services act of using it as check for defects of organs in face. In this paper, we performed analysis white pupils and left cheek in face area change of color according to accrue of alcohol associated with liver function status based on diagnosis method Oriental Medicine. From that, we applied Lab digital color system to extraction of left cheek and white pupils area in facial image. To analysis patterns in color change of left cheek. white pupils area according to alcohol accumulative steps carried out study based on analysis of medical interrelationship of liver function,

Protective effect of Phyllostachys edulis (Carrière) J. Houz against chronic ethanol-induced cognitive impairment in vivo

  • Jiyeon Kim;Ji Myung Choi;Ji-Hyun Kim;Qi Qi Pang;Jung Min Oh;Ji Hyun Kim;Hyun Young Kim;Eun Ju Cho
    • Nutrition Research and Practice
    • /
    • v.18 no.4
    • /
    • pp.464-478
    • /
    • 2024
  • BACKGROUND/OBJECTIVES: Chronic alcohol consumption causes oxidative stress in the body, which may accumulate excessively and cause a decline in memory; problem-solving, learning, and exercise abilities; and permanent damage to brain structure and function. Consequently, chronic alcohol consumption can cause alcohol-related diseases. MATERIALS/METHODS: In this study, the protective effects of Phyllostachys edulis (Carrière) J. Houz (PE) against alcohol-induced neuroinflammation and cognitive impairment were evaluated using a mouse model. Alcohol (16%, 5 g/kg/day for 6 weeks) and PE (100, 250, and 500 mg/kg/day for 21 days) were administered intragastrically to mice. RESULTS: PE showed a protective effect against memory deficits and cognitive dysfunction caused by alcohol consumption, confirmed through behavioral tests such as the T-maze, object recognition, and Morris water maze tests. Additionally, PE attenuated oxidative stress by reducing lipid oxidation, nitric oxide, and reactive oxygen species levels in the mice's brains, livers, and kidneys. Improvement of neurotrophic factors and downregulation of apoptosis-related proteins were confirmed in the brains of mice fed low and medium concentrations of PE. Additionally, expression of antioxidant enzyme-related proteins GPx-1 and SOD-1 was enhanced in the liver of PE-treated mice, related to their inhibitory effect on oxidative stress. CONCLUSION: This suggests that PE has both neuroregenerative and antioxidant effects. Collectively, these behavioral and histological results confirmed that PE could improve alcohol-induced cognitive deficits through brain neurotrophic and apoptosis protection and modulation of oxidative stress.

A Study on the Eco-Toxicity of Silicone-Based Antifoaming Agents Discharging into Marine Environments (해양으로 배출되는 실리콘계 소포제의 생태독성 연구)

  • Kim, Tae Won;Kim, Young Ryun;Park, MiOk;Jeon, MiHae;Son, Min Ho
    • Journal of the Korean Society of Marine Environment & Safety
    • /
    • v.25 no.1
    • /
    • pp.81-88
    • /
    • 2019
  • In order to understand the effects of the main components of antifoaming agents on the marine benthic ecosystem when silicone-based antifoaming agents are discharged into marine environments, eco-toxicity testing was performed on silicone and alcohol-based antifoaming agent by using benthic amphipod (Monocorophium acherusicum) and luminescent bacteria (Vibrio fischeri). The toxic effects of Polydimethylsiloxane (PDMS) as a main component of silicone-based antifoaming agents on aquatic organisms were also researched. In the results of the eco-toxicity test, luminescent bacteria showed a maximum of 9 times more toxic effects than benthic amphipod for alcohol-based antifoaming agents, and silicone-based antifoaming agents showed a maximum of 400 times more toxic effects than alcohol-based. The $LC_{50}$ and $EC_{50}$ values of PDMS ranged from 10 to $44,500{\mu}g/L$ in phytoplankton, invertebrate, and fish. In the results of applying PBT (P: persistency, B: bioaccumulation, T: toxicity) characteristics as an index showing the qualitative characteristics of PDMS, persistency (P) and bioaccumulation (B) were confirmed. Thus, when PDMS is discharged to marine environments, it could accumulate in the upper trophic level through bioaccumulation and the food chain, which could have negative effects on benthic organisms. The results of this study may be used for objective and scientific risk assessment, considering the major components of antifoaming agents when investigating the effects of various discharged antifoaming agents in marine ecosystem.