• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.4
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• pp.865-871
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• 2009

Chondroitin sulfate was extracted by alkali method and enzyme method from shark cartilage. In extract system, various processing parameters such as concentration of alkali and alcarase, temperature etc, have been investigated for optimization condition. The pure chondroitin sulfate was obtained by UF membrane separation. The characteristics was also investigated with gel permeation chromatograpy(GPC). The molecular weight of chondroitin sulfate was $2.7\times10^4$ Da.