• Title/Summary/Keyword: AiTtioxidant activity

Search Result 1, Processing Time 0.015 seconds

Discovery of Antioxidant on Human Low Density Lipoprotein (LDL) by Bacillus sp. RH-5 Isolated from Marine Origin (해양에서 분리한 Bacillus sp. RH-5에 의한 사람 Low Density Lipoprotein(LDL) 산화에 대한 항산화제의 개발)

  • 류병호;박종옥;김동석
    • Journal of Life Science
    • /
    • v.9 no.1
    • /
    • pp.99-105
    • /
    • 1999

  • The aims of this studies were carried out to investigate the antioxidant activity on low density lipoprotein(LDL) using substances extracted from Bacillus sp. RH-5. The antioxidative substances produced extracellular in the culture broth by Bacillius sp. RH-S was obtained by elution of chloroform : methanol from silicagel column (80cm x100cm) chromatography. Band 4 eluted from fraction 3 by TLC was appeared at highest level of antioxidative activity using thiocyanate methed. Band 4 at a concentration of 100 or 200$\mu$g/$m\ell$ inhibited oxidation of LDL induced by the mouse transformed macrophage. According to IR. NMR or GC/MASS, the antioxidant substance was identified as 5-hydroxyindole.

  • PDF