• Title/Summary/Keyword: Aging Techniques

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Inhibitory Effect of Ophioglossum vulgatum on Free Radical and MMP Expression in UV-irradiated Human Dermal Fibroblasts (병이소초 추출물의 항산화 및 MMP 발현 저해 효과)

  • Kim, Jin-Hwa;Oh, Jung-Young;Lee, Geun-Soo;Zhang, Yong-He;Pyo, Hyeong-Bae
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.35 no.4
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    • pp.287-292
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    • 2009
  • Human skin is constantly exposed to environmental irritants such as smoke, chemicals and ultraviolet (UV). Free radicals and reactive oxygen species (ROS) caused by these environmental irritants play critical roles in cellular damage. In this study, to investigate the skin cell protective effect of Ophioglossum vulgatum extract, we investigated its effects on intercellular antioxidative activity and UVA-induced MMP expression in human dermal fibroblasts (HDFs). The dried O. vulgatum was extracted in a mixture of ethanol and water (1 : 1) for 24 h at room temperature. The extract was filtered and concentrated in vacuo and lyophilized. For testing intracellular ROS scavenging activity the cultured HDFs were analyzed by increase in DCF fluorescence upon exposure to UVB $20\;mJ/cm^2$. After treatment of O. vulgatum extracts, intracellular ROS levels were measured by luminescence spectrophotometer. Enzyme linked immuno sorbent assay (ELISA), and RT-PCR techniques were used for evaluating the effects of O. vulgatumon on MMP protein and mRNA expression in UVA irradiated HDFs. O. vulgatum extract was found to have ROS scavenging activity with the $IC_{50}$ values of $18.2\;{\mu}g/mL$ against superoxide radicals in the xanthine/xanthine oxidase system. After treatment of O. vulgatum extracts, the oxidation of CM-DCFDA was inhibited effectively and O. vulgatum extracts showed a potent free radical scavenging activity by 30.4 % at $100\;{\mu}g/mL$ in UVB-irradiated HDFs. UVA induced MMP protein expression was reduced 37.7 % by treatment with O. vulgatum extract, and MMP-1 mRNA expression was reduced in a dose-dependent manner. Taken together, these results suggest that O. vulgatum extract prevents the skin cell damage induced by UV irradiation, and implies that O. vulgatum extract may be useful as a new ingredient for anti-aging cosmetics.

Determination of Pu Oxidation states in the HCl Media Using with UV-Visible Absorption Spectroscopic Techniques (UV-Visible 흡수분광학법을 이용한 염산매질내 Pu 산화상태 측정)

  • Lee, Myung-Ho;Suh, Mu-Yeol;Park, Kyoung-Kyun;Park, Yeong-Jae;Kim, Won-Ho
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.4 no.1
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    • pp.1-7
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    • 2006
  • The spectroscopic characteristics of Pu (III, IV, V, VI) in the HCl media were investigated by measuring Pu oxidation states using a UV-Vis-NIR spectrophotometer (400-1200 nm) after adjusting Pu oxidation states with oxidation/reduction reagents. Pu in stock solution was reduced to Pu(III) with $NH_2OH$ HCl, and oxidized to Pu(IV) and Pu(VI) with $NaNO_2$ and $HClO_4$, respectively. Also, Pu(V) was adjusted in the Pu(VI) solution with $NH_2OH$ HCl. The major absorption peaks of Pu (IV) and Pu(III) were measured in the 470 m and 600 nm, respectively. The major absorption peaks of Pu (VI) and Pu(V) were measured in the 830 nm and 1135 nm, respectively. There was not found to be significant changes of UV-Vis absorption spectra for Pu(III), Pu(IV) and Pu(VI) with aging time, except that an unstable Pu(V) immediately reduced to Pu(III).

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Ergonomic Assessment for Manual Materials Handling of Livestock Feed by Elderly Farmers in Korea

  • Kim, Insoo;Lee, Kyung-Suk;Kim, Kyung-Ran;Chae, Hye-Seon;Kim, Sungwoo
    • Journal of the Ergonomics Society of Korea
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    • v.34 no.3
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    • pp.279-291
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    • 2015
  • Objective: The purpose of the study is to evaluate appropriate weight for aged farmers in manually handling livestock feed in bags using ergonomic methods. Background: In the livestock industry in South Korea, despite the trend of aging of labor manpower, heavy items are still manually handled in many farms. In particular, among stockbreeding works, the handling of feed in bags weighing 25~30kg is reported as a cause of frequent injuries and musculoskeletal system diseases. However, studies on the standard for recommended weight allowed considering the physical characteristics of aged farmers older than 60 years with greatly decreased physical strength and muscle strength are insufficient. Method: To evaluate appropriate weight for handling of heavy livestock feed in bags, physical techniques for measuring recognized levels of physical work loads, the NLE (NIOSH lifting equation) a method that is an observation type technique, and an ergonomic modeling technique to predict compressive force imposed on L5/S1 were used. Subjects who participated in the experiment were organized into two groups of males/females with mean age exceeding 60 years, and lifting tasks were evaluated for nine weight levels. Results: Based on the results of psychophysical measurement, females showed a tendency of more drastic increases compared to males when weight was over 19kg. The results of estimation of regression models for the weight, 18.0 kg ($r^2=0.97$) and 15.3kg ($r^2=0.97$) were evaluated as stable load for males and females, respectively. In addition, both the observation type evaluation and ergonomic model evaluation showed stable loads in a range of 15~18kg. Conclusion: Given the results of the study, the weight of the feed in bags currently distributed to farms can become a cause of not only overexertion but also farm work related disasters such as musculoskeletal disorders and safety accidents. Providing livestock feed in bags weighing not more than 19kg for aged farmers is judged desirable, and managerial improvement for this matter is considered necessary. Application: The results of the present study can be utilized as useful data for institutional improvement of the weight of livestock feed in bags.

The Phenomenoloical Study on the Stress of Family Caregivers with Demented Elderly (치매노인 부양가족의 스트레스에 관한 현상학적 연구)

  • Lee, Young-man;Shin, Dong-yeol
    • Industry Promotion Research
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    • v.5 no.2
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    • pp.41-50
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    • 2020
  • WIn Korea, the rapid rise of elderly population and dementia prevalence resulting from the unprecedently rapid aging in the world is being emerged as a serious social issue. Caring the elderly with dementia is a different way from a general life and is a world which new cultural existential relationships are interlaced from the relationship viewpoint. From this aspect, the psychological matter of family caring a demented elderly needs to be studied for existential understanding in depth and fundamentally. This study focused on in-depth understanding and description of the stress phenomena experienced by family caregivers with a demented elderly based on Giorgi's method among phenomenological research methods and using existential group counseling techniques. Total 8 sessions of existential group counseling were conducted. This study drew out the outcomes(emotional stress, psychosocial stress, time-dependent stress) of participants' self-awareness experiences by applying 4 steps of Giorgi's phenomenological research methodology based on the Existential Philosophy to participant's intensive statements about stress of family caring a demented elderly drawn out of the existential group counselling sessions. It is hoped that understanding the pain of the supporters who cannot express their own pains through the research results and their self-help group counseling activities will become active, contributing to the health of our society which is about to enter post-aged society.

An Evaluation on Electrochemical Polarization Characteristics and Material Degradation for Cr-Mo-V Steel (Cr-Mo-V강의 전기화학적 분극 특성과 재질열화 평가)

  • Kwon, Il-Hyun;Lee, Song-In;Ha, Jeong-Soo;Yu, Hyo-Sun
    • Journal of the Korean Society for Nondestructive Testing
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    • v.22 no.3
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    • pp.267-274
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    • 2002
  • This research is described on the applicability of a electrochemical techniques for evaluating nondestructive material degradation with various polarization characteristics for Cr-Mo-V steel. The applied electrochemical technique is anodic polarization test which are widely used to evaluate the corrosion rate and/or sensitization at depleted zone of strengthening elements mainly caused by thermal experience for stainless steels. The evaluation of material degradation is performed by small punch test which has been well known as micromechanics test method using specimen size of $10{\times}10{\times}0.5mm$. The 1,000hrs aged material at $630^{\circ}C$ shows the highest material degradation$({\Delta}[DBTT]_{SP})$, but the 2,000hrs and 3,000hrs aged materials show the decrease of ${\Delta}[DBTT]_{SP}$ as aging time increases. It is observed that the difference of current density $({\Delta}I_{FP}\;and\;{\Delta}I_{SP})$.

An Ethnography of the Concept of Illness by the Elderly (노인의 질병 관념에 관한 문화기술적 연구)

  • Cho, Myoung Ok
    • Korean Journal of Adult Nursing
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    • v.12 no.4
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    • pp.690-705
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    • 2000
  • This ethnography was based on Kleinman's explanatory model of a health care system. It is conducted to make thick discription of illness conception of the elderly in a sociocultural context. The basic assumptions were as follows. 1) A health care system is a cultural system, and as with any other cultural system, it is a system of symbolic meanings anchored in a particular arrangement of social institutions and patterns of interpersonal relationships; 2) In all societies health care activities are more or less interrelated. Therefore, they need to be in a holistic manner as socially organized responses to disease that constitute a special cultural system; health care system; 3) Health and illness experiences are the natural process of disease. Individuals who recognized a for state of health, their family, neighbors, and communities define the state, search for causes of the health problems, and response to it. According by, they proceed to search for healing stratagies. So, understanding of the illness experience is the starting point for health care. The study participants were 12 elders aged 60 or more. The fieldwork was conducted in an agricultural clan village of Namwon city. The data collection and analysis were cyclic, from descriptive observation, domain analysis, focused observation, taxanomic analysis, selected observation, componential analysis, and finally cultural themes were all analysed. Proxemic and text analysis techniques were used according to the characteristics of the data. The data of sociocultural context and descriptive data were collected from 1990 to 1992. Informations on illness concepts were collected during 1994 using focused observation. Data confirming and contrast observations were conducted from 1997 and 1999. Illness concepts of the elderly were taxonomized supernatural cause, non-supernatural cause, immediate cause, and ultimate cause. The supernatural ones were ancestors, god of home, god of village, and ghost such as 'sal(evil force of dead man)' and 'gagqui(ghost of begger)'. The non-supernatural ones were Ki, natural phenomenones, natural objects, foods, human and human behaviors. Immediate ones were insufficiency and overflows, discretion and consolidation, disorder and out of order, cloudness and contamination, and fluctuation and stagnation of supernatural cause and non-supernatural ones. Ultimate causes were intrusion and loss of supernatural and nonsupernatural ones. The cultural themes of illness concepts of the elderly are: 1) illness concepts are not based on causality principle, but on reciprocal principle; 2) illness concepts are affected by social level and charicteristics of the patients; 3) the causes of disease are recognized as imposed both positive and negative effects on health based on interpretation of the indiviuals; 4) illness concepts reflects on principles of everyday life of the society members such as hierachial structure and group cohesiveness; 5) illness concepts are ruled on principle of reciprocity and spread; 6) illness concepts are interrelated with physical environment of the participants. It can be concluded that the illness concepts of the elderly in a traditional clan village are a component of health care system as a cultural system based on these results. The these results can be a useful basis for gerontological nursing practice and education.

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Preliminary Study on the Simulation for Urban Railway Facility Performance Assessment (도시철도시설 성능평가 시뮬레이션 구현을 위한 기초 연구)

  • Kang, Goune;Jung, Insu;Kim, Jung-yeol;Seo, MyoungBae
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.3
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    • pp.190-198
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    • 2020
  • For domestic urban railways, which have a 19.7% aging rate, a performance evaluation is necessary to establish capital improvement investment plans. The performance evaluation, which was recently enacted in the relevant law, points out the excessive time and effort for acquiring data and evaluation. This study developed a performance evaluation simulation prototype using a virtual reality (VR) method to use as training contents for railway performance evaluations. The practical use of the VR technique to reduce the working time under poor environment conditions was confirmed through a literature review. A survey and consultation were conducted for urban railway experts to determine the weight of the performance evaluation items and the facility breakdown structure. This information was utilized to develop performance evaluation sheets for simulation. Based on the evaluation sheet, a training content prototype that evaluates the performance of platform safety doors was developed using VR techniques with HTC VIVE equipment. VR simulation tests were conducted for six players, and the prototype was sufficiently advantageous for a visual confirmation of the facility information. The result is expected to be useful for engineers to understand the performance evaluation process efficiently before an actual performance evaluation of urban railway facilities.

Design and Development of Personal Healthcare System Based on IEEE 11073/HL7 Standards Using Smartphone (스마트폰을 이용한 IEEE 11073/HL7 기반의 개인 건강관리 시스템 설계 및 구현)

  • Nam, Jae-Choong;Seo, Won-Kyeong;Bae, Jae-Seung;Cho, You-Ze
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.36 no.12B
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    • pp.1556-1564
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    • 2011
  • The increased life expectancy of human due to the advance of medical techniques has led to many social problems such as rapidly aging populations, increased medical expenses and a lack of medical specialists. Thus, studies on improving the quality of life with the least amount of expense have been going on by incorporating advanced technologies, especially for Personal Health Devices (PHDs), into the medical service market. However, compatibility and extensibility among manufacturers of PHDs have not been taken into account in most of the researches done on the development of PHDs because most of them have been supported by individual medical organizations. The interoperability among medical organizations can not be guaranteed because each medical organization uses different format of the messages. Therefore, in this paper, an expansion module that can enable commercially-available non-standard PHDs to support the IEEE 11073, and a smart-phone-based manager that can support easy and comprehensive management on receiving and transmitting the collected data from each PHD using IEEE 11073 standard were developed. In addition, a u-health system that can transmit the data collected in the manager using the standard data format HL 7 to medical center for real-time medical service from every medical institutions that support this standard was designed and developed.

Evaluation of Effect of Long Period Usage of Concentrated Ginseng Cream Using Eastern and Western Medicine Techniques (인삼농축크림 장기사용자의 동서의학적 피부 특성 고찰)

  • Cho, Ga Young;Yeom, Myung Hun;Park, Seong Il;Cho, Jun Cheol;Yu, Sun Hye;Choi, Yoon Jung;Kim, Jong Il
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.39 no.3
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    • pp.167-175
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    • 2013
  • The aim of this study is to evaluate the effect of cosmetic products containing concentrated ginseng using novel methods based on Traditional Korean medicine (TKM). In TKM, inspection of facial skin was an important method to diagnose symptoms and body condition of patients. Doctors in oriental medicine examined a patient as observing symptoms on the face and skin related to inner organs. This was called "mang-jin. In this study, eleven female, who have been using the cosmetic products containing concentrated ginseng for the last 5 years, and eleven healthy controls, who have never used the same product, were recruited. Three doctors in oriental medicine evaluated 17 inspection factors on facial skin. And 7 non-invasive skin bioengineering factors were assessed by various instruments at the same time. In results, 7 factors of the inspection were better in using the product than in controls. And sebum, roughness, pigmentation and wrinkle depth were significantly lower in using the product than in controls. So, this results propose that the cosmetic product containing concentrated ginseng has a good anti-aging effect on skin. And it is suggested that the novel evaluation method combined, Traditional Korean medicine and modern bioengineering technique, has to be developed for holistic concept of Hanbang cosmetics.

Development of FURA Code and Application for Load Follow Operation (FURA 코드 개발과 부하 추종 운전에 대한 적용)

  • Park, Young-Seob;Lee, Byong-Whi
    • Nuclear Engineering and Technology
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    • v.20 no.2
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    • pp.88-104
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    • 1988
  • The FUel Rod Analysis(FURA) code is developed using two-dimensional finite element methods for axisymmetric and plane stress analysis of fuel rod. It predicts the thermal and mechanical behavior of fuel rod during normal and load follow operations. To evaluate the exact temperature distribution and the inner gas pressure, the radial deformation of pellet and clad, the fission gas release are considered over the full-length of fuel rod. The thermal element equation is derived using Galerkin's techniques. The displacement element equation is derived using the principle of virtual works. The mechanical analysis can accommodate various components of strain: elastic, plastic, creep and thermal strain as well as strain due to swelling, relocation and densification. The 4-node quadratic isoparametric elements are adopted, and the geometric model is confined to a half-pellet-height region with the assumption that pellet-pellet interaction is symmetrical. The pellet cracking and crack healing, pellet-cladding interaction are modelled. The Newton-Raphson iteration with an implicit algorithm is applied to perform the analysis of non-linear material behavior accurately and stably. The pellet and cladding model has been compared with both analytical solutions and experimental results. The observed and predicted results are in good agreement. The general behavior of fuel rod is calculated by axisymmetric system and the cladding behavior against radial crack is used by plane stress system. The sensitivity of strain aging of PWR fuel cladding tube due to load following is evaluated in terms of linear power, load cycle frequency and amplitude.

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