• Title/Summary/Keyword: Aging Factor

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The Relationships between Plasma Insulin-like Growth Factor (IGF)-1 and IGF-Binding Proteins (IGFBPs) to Growth Pattern, and Characteristics of Plasma IGFBPs in Steers

  • Lee, H.G.;Hidari, H.;Kang, S.K.;Hong, Z.S.;Xu, C.X.;Kim, S.H.;Seo, K.S.;Yoon, D.H.;Choi, Y.J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.11
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    • pp.1575-1581
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    • 2005
  • This study was conducted to determine the characteristics of IGFBPs in plasma of steers, and to profile the relationship between growth and plasma IGF-1 and IGFBPs with aging in Holstein steers. Four blots of IGFBP at molecular weights of 38-43, 34, 29-32 and 24 kDa bands were detected by western ligand blot assay using $^{125}I-IGF-1$. On the basis of immunoblotting with anti-bovine IGFBP-2 and -3 antiserums, we observed the band for IGFBP-2 at approximately 34 kDa, and the IGFBP-3 band was detected at 38-43 kDa and 34 kDa in adult steers and calves. The IGFBP-3 antiserum used on the blots exhibited significant cross-reactivity with 34 kDa IGFBP-2. Furthermore, the 38-43 kDa IGFBP-3 bands were reduced to a 36 kDa band after deglycosylation, whereas the 34 kDa IGFBP-2 was intact. The plasma IGF-1, IGFBP-3 and other IGFBPs showed stability throughout a whole day. The change in live weight was found to be positively correlated to the plasma IGF-1 concentration (r = 0.6801, n = 64, p<0.05) and plasma IGFBP-3 (r = 0.6321, n = 64, p<0.05), while inversely correlated to plasma IGFBP-2 (r = -0.2919, n = 64, p<0.05). Furthermore, plasma IGF-1 was positively correlated to plasma IGFBP-3 (r = 0.6191, p<0.001), but was not correlated to plasma IGFBP-2. The portion of IGFBP-2 for total IGFBPs in calves was higher than in adult steers (p<0.05) and was decreased with growth, whereas that of IGFBP-3 was increased with increased live weight (p<0.05). The ratio IGFBP-3 for IGFBP-2 (BP-3/BP-2) was increased with growing of liveweight. Therefore, the changes in plasma IGF-1 level with increased liveweight may be related to the changes in plasma IGFBP-3 level and IGFBP-2 may give an important role in anabolic action of IGF-1 with the growth of body during calfhood in Holstein steers.

Reaction to the Vehicle and Trade-off Between Vehicular Interruption and Food Resources of Cranes - Focused on the Wintering Cranes in Cheorwon Basin, Korea- (두루미류의 차량에 대한 반응 및 방해요인과 먹이 자원 사이의 절충 - 철원분지에서 월동하는 두루미와 재두루미를 중심으로 -)

  • Yoo, Seung-Hwa;Lee, Ki-Sup;Yoo, Jeong-Chil
    • Korean Journal of Environment and Ecology
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    • v.21 no.6
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    • pp.526-535
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    • 2007
  • This study was conducted at the Civilian Controlled Zone(CCZ) in the Cherowon from February to March 2004 to investigate the reaction to the vehicles of Red-crowned Cranes(RCC) and White-naped Cranes(WNC) and trade-off of the vehicle interruption with food resources. The for-aging distance from the road of WNC was much closer than that of RCC. The large flocks of cranes' average feeding distance from the road was farther than small flocks of cranes in both species. Cranes showed the reaction, such as alert, walking, running and flying against the vehicle stop and were more sensitive as they were close to the road. The reacting time to the stopping vehicle were reduced as it was farther from the road. The distance of about 250m was a reaction threshold distance against the vehicle stop to both species. The reacting time in the same distance was not different in relation to the traffic volume, but large traffic volume tended to cause cranes to stay far away from the road and not to feed themselves near a traffic congested area. The reason cranes fed themselves on fallen rice grains in spite of the vehicular traffic interruption factor was that there was a high density of the fallen rice grains remaining at the area near a road.

Analysis on the perception of body image and awareness of diet among high school students in Zibo city, China (중국 치박시(淄博市) 고등학생의 체형에 대한 인식 및 다이어트에 대한 태도 분석)

  • Kim, Hyochung;Sun, Xiaoqing;Kim, Meera
    • Journal of Korean Home Economics Education Association
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    • v.24 no.4
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    • pp.59-75
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    • 2012
  • This study investigated the self-perception of body image and awareness of diet of high school students in Zibo city, China. The data were collected from 260 high school students through the self-administered questionnaires. Frequency analysis, t tests, one-way ANOVA, Duncan's multiple range tests, factor analysis and Cronbach's alpha test were conducted by SPSS Windows V.19.0. The results were as follows. In the self-perception of body image, two fifths of the respondents thought of themselves as standard body image. More female respondents thought of themselves as fat persons compared with male respondents. The level of concern about diet was generally low and the mean for pursuit of skinny figure was highest in the awareness of diet. The percentage of correct answers of knowledge about diet was not that high, and one fifths of respondents had experience of diet. The respondents practiced fasting therapy, exercise therapy, food therapy, sweat therapy, drug/appliance therapy, and therapy using professional organization in order for diet.

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Self-Rated Health, Depression, and Life Satisfaction of Babyboomers in Korea: Multiple Group Analysis according to Their Work Status (베이비부머의 주관적 건강상태, 우울, 삶의 만족도의 관계: 근로여부에 따른 다중집단분석)

  • Song, Inuk;Won, Seojin
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.6
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    • pp.349-357
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    • 2020
  • This study aimed to examine the effects of self-rated health on life satisfaction among Korean babyboomers and to address the mediating effect of depression on the self-rated health-life satisfaction relationship. Further, this study attempted to identify any relationship between self-rated health, depression, and life satisfaction among babyboomers according to work status. Researchers conducted a secondary data analysis using the 6th wave of the Korean Longitudinal Study on Aging. The final sample was 2,479 babyboomers born between 1955 and 1963. Testing the mediating effect of depression was done by the significance of direct, indirect, and total effects. Researchers also compared an unconstrained model with constrained model for multiple group analysis. Results indicate that self-rated health was a significant factor in determining the life satisfaction of babyboomers. In addition, depression had a significant mediating effect on the self-rated health and life satisfaction of babyboomers. Multiple group analysis demonstrated, in the non-working babyboomer model, the effects of self-rated health and depression on life satisfaction, and the effect of depression on life satisfaction was stronger than that of the working babyboomer model. The results of this study have established the importance of health and working status in addressing depression and life satisfaction among babyboomers.

Understanding the Correlation Between Dorsiflexion Range of Motion and Dynamic Balance in Elderly and Young Adults (노인과 젊은 성인의 발목발등굽힘 관절가동범위와 동적 균형 상관성 대한 이해)

  • Seo, Hae-yong;Han, Ji-hye;Kim, Min-ju;Kim, Ah-yeon;Song, Yi-seul;Kim, Su-jin
    • Physical Therapy Korea
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    • v.25 no.2
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    • pp.22-29
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    • 2018
  • Background: Deficits of both ankle dorsiflexion range of motion (DFROM) and dynamic balance are shown in persons with chronic ankle instability and the elderly, with the risk of falls. Objects: This study aims to investigate the relationship between DFROM and dynamic balance in elderly subjects and young adults. Methods: Fifty-nine subjects were divided into three groups: ankle stability young group (SY), ankle instability young group (IY) and ankle stability older group (SO). We recruited three old subjects with ankle instability, but excluded them during a pilot testing due to the safety issue. DFROM was measured by weight bearing lunge test (WBLT) and dynamic balance was measured via star excursion balance test (SEBT) in anteromedial, medial, and posteromedial directions. The group differences in WBLT and SEBT and each group's correlation between WBLT and SEBT were detected using the R statistical software package. Results: The dorsiflexion range of motion was significantly different between the SY, IY, and SO groups. The SO group showed the highest DFROM and IY group showed the lowest DFROM (SY: $45.88{\pm}.66^{\circ}$, IY: $39.53{\pm}1.63^{\circ}$, SO: $47.94{\pm}.50^{\circ}$; p<.001). However, the SO group showed the lowest dynamic balance score for all SEBT directions (SY: $87.24{\pm}2.05cm$, IY: $83.20{\pm}1.30cm$, SO: $77.23{\pm}2.07cm$; p<.05) and there was no relationship between the dorsiflexion range of motion and dynamic balance in any group. Conclusion: Our findings suggest that ankle DFROM is not a crucial factor for dynamic stability regardless of aging and ankle instability. Other factors such as muscle strength or movement coordination should be considered for training dynamic balance. Therefore, we need to establish the rehabilitation process by measuring and treating ROM, balance, and muscle strength when treating young adults with and without ankle instability as well as elderly people.

Effect of Zanthoxylum piperitum Extract on Human Skin Protection from UVB by Regulation of COP1 and PPAR-α (초피나무 열매 추출물의 COP1 및 PPAR-α 조절을 통한 자외선에 대한 피부 보호 효과)

  • Kim, Yun-Sun;Kim, Yumi;Lee, Sanghwa
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.42 no.4
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    • pp.393-401
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    • 2016
  • Ultraviolet (UV) irradiation from the sun is the primary environmental factor that causes skin damages including skin cancer and premature skin aging. Because, even the most powerful sunscreen can't always afford enough protection, it is necessary to enhance the defensive power of skin against UV. Recently, constitutive photomorphogenic protein-1 (COP1) has shown to contribute to the regulation of UVB response of keratinocytes. In this study, we represent that COP1 and its associated protein, de-etiolated 1 (DET1), might participate in photoaging process in human skin as Arabidopsis COP1 does sun-protective function in plants. After UVB irradiation, the decrease of COP1 and DET1 mRNA expression was followed by the increase of c-Jun total protein. Moreover, transfection with DNA vectors expressing COP1 and DET1 down-regulated the c-Jun total protein. We found that Zanthoxylum piperitum extract (ZE) up-regulated the expression of COP1 and DET1 on human keratinocytes, and inhibited the expression of MMP1 which is one of the genes regulated by c-Jun signal. In addition, ZE has been reported to stimulate PPAR-${\alpha}$ and strengthen the skin barrier. We found that ZE decreased the UVB-induced IL-6 and IL-8 in NHEK cells. In human study, ZE protected skin against UV-B induced erythema and erythema-induced pigmentation. These results indicate that ZE could be useful for the protection against the adverse effects of UV irradiation through various mechanisms.

Using IoT and Apache Spark Analysis Technique to Monitoring Architecture Model for Fruit Harvest Region (IoT 기반 Apache Spark 분석기법을 이용한 과수 수확 불량 영역 모니터링 아키텍처 모델)

  • Oh, Jung Won;Kim, Hangkon
    • Smart Media Journal
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    • v.6 no.4
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    • pp.58-64
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    • 2017
  • Modern society is characterized by rapid increase in world population, aging of the rural population, decrease of cultivation area due to industrialization. The food problem is becoming an important issue with the farmers and becomes rural. Recently, the researches about the field of the smart farm are actively carried out to increase the profit of the rural area. The existing smart farm researches mainly monitor the cultivation environment of the crops in the greenhouse, another way like in the case of poor quality t is being studied that the system to control cultivation environmental factors is automatically activated to keep the cultivation environment of crops in optimum conditions. The researches focus on the crops cultivated indoors, and there are not many studies applied to the cultivation environment of crops grown outside. In this paper, we propose a method to improve the harvestability of poor areas by monitoring the areas with bad harvests by using big data analysis, by precisely predicting the harvest timing of fruit trees growing in orchards. Factors besides for harvesting include fruit color information and fruit weight information We suggest that a harvest correlation factor data collected in real time. It is analyzed using the Apache Spark engine. The Apache Spark engine has excellent performance in real-time data analysis as well as high capacity batch data analysis. User device receiving service supports PC user and smartphone users. A sensing data receiving device purpose Arduino, because it requires only simple processing to receive a sensed data and transmit it to the server. It regulates a harvest time of fruit which produces a good quality fruit, it is needful to determine a poor harvest area or concentrate a bad area. In this paper, we also present an architectural model to determine the bad areas of fruit harvest using strong data analysis.

Scenario Analysis of Fertility in Korea using the Fertility Rate Prediction Model (출산율 예측모형을 이용한 한국의 출산력 시나리오 분석)

  • Kim, Keewhan;Jeon, Saebom
    • The Korean Journal of Applied Statistics
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    • v.28 no.4
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    • pp.685-701
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    • 2015
  • The low fertility rate and the unprecedented rapid pace of population aging is a significant factor degrading the national competitiveness and the social security system of Korea. The government has implemented various maternity incentives to alleviate the low birth problem; however, the policy seems in effective to solve the problem of low fertility. This study proposes a conditional birth-order specific fertility rate and investigates the policy effects of fertility transition in Korea to provide a basis for more effective policy development. The use of a conditional birth-order specific fertility rate allows for an effective calculation of the change and the effect in total fertility rate than a birth-order specific fertility rate. We compare the effects of the total fertility rate according to various scenarios that enables us to calculate how the total fertility rate can achieve the current multi-child childbirth support policy of the government and estimate how the total fertility rate can be achieved when focusing on the first or second childbirth support policy. We also summarize the research results on policy development for a practical increase in the childbirth that considers the rapid decrease in women of childbearing age (15-49 years) due to continued low fertility and present the number of childbirths in accordance with the total fertility rate.

Effect of Nuclear Transfer Methods on In Vitro Development of Reconstituted Bovine Embryos II. Effect of Electric Voltage and In Vitro Produced Donor Embryo Quality on Fusion and In Vitro Development (소에서 핵이식 방법이 재구축배의 체외발달에 미치는 영향 II. 통전전압과 체내생산 공핵배의 질에 따른 융합과 체외발달)

  • 정영채;김창근;송학웅;정영호;윤종택;이종완;김흥률;김광식
    • Korean Journal of Animal Reproduction
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    • v.20 no.4
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    • pp.467-472
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    • 1997
  • This study was conducted to determine the optimal DC voltage for NT of in vivo donor embryo nuclei and investigate the effect of donor embryo guality on fusion and in vitro development of NT embryos . Recpient oocytes were enucleated 25~27h after IVM and further cuitured for 18~20h prior to fusion for oocyte aging. Donor embryos of molura stage were recovered from superovulated heifers and classified l into good and low quality group. Their nuclei were transferred in to the emucleated oocytes 42~44h post-IVM and fused 43-45h post-IVM with a single 0.75kV /cm or 1.0kV /cm DC voltage for 70${\mu}\textrm{A}$sec. The fusion rate of oocytes was not different between two DC voltages. However, the cleavage and M + B developmnent was more high at 1.0kV /cm DC voltage and the proportion of M+B was 19.0% at 0.75kV /cm DC and 29.4% at 1.0kV /cm DC voltage. Donor embryo qualtiy did not greatly affect the fusion and cleavage of NT oocytes, but none of NT embryos derived from low embryo quatity reached the morula stage. The results indicate that the most suitable DC v voltage for electrofusion of in vivo donor muclei was a single 1.0kV /cm DC voltage and donor embryo quality was an important factor affecting the development in vitro of NT embryos.

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Characteristics of N2O Emission Factor and Measurements from Gasoline-Powered Passenger Vehicles (국내휘발유 승용차량으로부터의 N2O배출인자 특성연구)

  • Kim, Deug-Soo;Ryu, Jeong-Ho;Yoo, Young-Sook;Jung, Sung-Woon;Kim, Dae-Wook
    • Journal of Environmental Science International
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    • v.16 no.2
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    • pp.179-185
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    • 2007
  • Nitrous oxide ($N_2O$) is an important trace gas in the atmosphere not only because of its large global warming potential (GWP) but also because of the role in the ozone depletion in the stratosphere. It has been known that soil is the largest natural source of $N_2O$ in global emission. However, anthropogenic sources contributing from industrial section is likely to increase with rising the energy consumption, and transportation as well. In this study, a total of 32 gasoline-powered passenger vehicles (ranging from small to large engine's displacement and also ranging from aged catalyst to new catalyst) were tested on the chassis dynamometer system in order to elucidate the characteristics of $N_2O$ emission from automobiles under different driving modes. Ten different driving modes developed by NIER were adapted for the test. The results show that the $N_2O$ emission decreases logarithmically with increase of vehicle speed over the all test vehicles ($N_2O$) emission = -0.062 Ln (vehicle speed) + $0.289,\;r^2=0.97$). It revealed that the larger engine's displacement, the more $N_2O$ emission were recorded. The correlation between $N_2O$ emission and catalyst aging was examined. It found that the vehicles with aged catalyst (odometer record more than 8,0000km) emit more $N_2O$ than those with new catalyst. Average $N_2O$ emission was $0.086{\pm}0.095\;N_2O-g/km$ (number of samples=210) for the all test vehicles over the test driving modes.