• 생약학회지
• /
• 제34권4호통권135호
• /
• pp.314-317
• /
• 2003

Inhibitory effects of the whole extract and isolated compounds from the leaves of Vaccinium koreanum (Ericaceae) on rat lens aldose reductase (RLAR) and on platelet aggregation were investigated for the prevention or the treatment of chronic diabetic complications. Arbutin, isolated from n-butanol fraction of methanol extract, exhibited a potent inhibitory effects on rat platelet aggregation induced by ADP $(IC_{50}=0.12\;{\mu}M)$ and collagen $(IC_{50}=0.039\;{\mu}M)$ and showed same inhibitory activities with positive control, tetramethylene glutaric acid, on RLAR.

• 한국정보처리학회:학술대회논문집
• /
• 한국정보처리학회 2009년도 추계학술발표대회
• /
• pp.707-708
• /
• 2009

In this paper, we provide a tradeoff solution to two conflicting requirements in VANET; Privacy and Aggregation. The information about traffic density is an important factor of aggregation in VANET. In our proposed scheme, densely located Road-Side Units (RSU) perform traffic density calculation and then aggregate the traffic information extracted from beacons received from the vehicles. RSUs then disseminate the aggregated traffic information to all the vehicles and neighbor RSUs. We use identityless beaconing thereby providing privacy and we do not consider the content security of beacons. We show that our scheme provides privacy in the case of aggregation, which has not been considered in previous schemes.

• Environmental Engineering Research
• /
• 제22권1호
• /
• pp.61-74
• /
• 2017

This study investigated the effect of various cations ($Ca^{2+}$, $Mg^{2+}$, $Al^{3+}$, $Mn^{2+}$, $Zn^{2+}$) on the autoaggregation (AAg) and surface hydrophobicity (SHb) of three different bacteria (Brevibacillus panacihumi strain (ZB1), Lysinibacillus fusiformis strain (ZB2) and Enterococcus faecalis strain (ZL)) using a 2-level factorial design. The AAg ratio was measured from the changes in the absorbance of the media. Results show that ZB2 had maximum AAg for the three bacteria investigated. A microscopic clustering of cells was observed when $Ca^{2+}$ was added to ZB2. The AAg was in the range of 62%, 58% and 34% for ZB2, ZB1 and ZL, respectively and correlated to the SHb. The aggregation and SHb of the microbial cells increased with increasing ionic strength due to the repulsive steric or overlap forces between the polymer covered surfaces. $Ca^{2+}$ demonstrated a more significant effect on aggregation and SHb of microbial cells due to an attractive binding force.

• 한국균학회지
• /
• 제31권2호
• /
• pp.114-116
• /
• 2003

농업과학기술원에서 분양 받은 52종의 버섯류의 자실체와 균사체들의 물 추출물과 에탄올 추출물에 대한 혈소판 응집억제 활성과 혈전용해활성을 조사하였다. 차가버섯 ASI 74006 균사체의 에탄올 추출물이 81.2%로 가장 높은 ADP 유도 혈소판 응집 억제활성을 보였고 그 다음은 장수버섯 자실체 에탄올 추출물들이 높았다. 그리고 혈전용해활성은 신령버섯 ASI 1174 균사체의 에탄올 추출물이 9.6 unit로 가장 높았으며 다른 버섯류는 대체로 낮았다.

• Journal of Information Processing Systems
• /
• 제11권1호
• /
• pp.148-164
• /
• 2015

The use of mobile agents for collaborative processing in wireless sensor network has gained considerable attention. This is when mobile agents are used for data aggregation to exploit redundant and correlated data. The efficiency of agent-based data aggregation depends on the agent migration scheme. However, in general, most of the proposed schemes are centralized approach-based schemes where the sink node determines the migration paths for the agents before dispatching them in the sensor network. The main limitations with such schemes are that they need global network topology information for deriving the migration paths of the agents, which incurs additional communication overhead, since each node has a very limited communication range. In addition, a centralized approach does not provide fault tolerant and adaptive migration paths. In order to solve such problems, we have proposed a distributed approach-based scheme for determining the migration path of the agents where at each hop, the local information is used to decide the migration of the agents. In addition, we also propose a local repair mechanism for dealing with the faulty nodes. The simulation results show that the proposed scheme performs better than existing schemes in the presence of faulty nodes within the networks, and manages to report the aggregated data to the sink faster.

• BMB Reports
• /
• 제35권6호
• /
• pp.590-594
• /
• 2002

To elucidate the effect of gamma-irradiation on the molecular properties of myoglobin, the secondary and tertiary structures, as well as the molecular weight size of the protein, were examined after irradiation at various irradiation doses. Gamma-irradiation of myoglobin solutions caused the disruption of the ordered structure of the protein molecules, as well as degradation, cross-linking, and aggregation of the polypeptide chains. A SDS-PAGE study indicated that irradiation caused initial fragmentation of the proteins and subsequent aggregation, due to cross-linking of the protein molecules. The effect of irradiation on the protein was more significant at lower protein concentrations. Ascorbic acid protected against the degradation and aggregation of proteins by scavenging oxygen radicals that are produced by irradiation. A circular dichroism study showed that an increase of the irradiation decreased the a-helical content of myoglobin with a concurrent increase of the aperiodic structure content. Fluorescence spectroscopy indicated that irradiation increased the emission intensity that was excited at 280 nm.

• Bulletin of the Korean Chemical Society
• /
• 제34권1호
• /
• pp.188-196
• /
• 2013

We have investigated the effects of formalin on the assembly of colloidal gold nanoparticles (AuNPs) prepared by laser ablation of a solid gold target in deionized water. Upon addition of formalin, the surface plasmon resonance (SPR) band at 519 nm for pure AuNPs decreases and shifts to red while a new broad SPR band appears at ~700 nm. The red-shift is prominent with increase in the incubation time. The average size of the initial AuNPs is around 12 nm but it increases to 23 nm after addition of formalin. It turns out that formalin acts as a cationic surfactant for AuNPs with negative surface charge in the colloidal solutions. Furthermore, through analysis of the Raman spectrum of formalin and the density functional theory calculations, we confirm that methanediol is the main species in formalin which is in charge of the aggregation of AuNPs.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• 제11권10호
• /
• pp.4717-4737
• /
• 2017

Today, smart grids, smart homes, smart water networks, and intelligent transportation, are infrastructure systems that connect our world more than we ever thought possible and are associated with a single concept, the Internet of Things (IoT). The number of devices connected to the IoT and hence the number of traffic flow increases continuously, as well as the emergence of new applications. Although cutting-edge hardware technology can be employed to achieve a fast implementation to handle this huge data streams, there will always be a limit on size of traffic supported by a given architecture. However, recent cloud-based big data technologies fortunately offer an ideal environment to handle this issue. Moreover, the ever-increasing high volume of traffic created on demand presents great challenges for flow management. As a solution, flow aggregation decreases the number of flows needed to be processed by the network. The previous works in the literature prove that most of aggregation strategies designed for smart grids aim at optimizing system operation performance. They consider a common identifier to aggregate traffic on each device, having its independent static aggregation policy. In this paper, we propose a dynamic approach to aggregate flows based on traffic characteristics and device preferences. Our algorithm runs on a big data platform to provide an end-to-end network visibility of flows, which performs high-speed and high-volume computations to identify the clusters of similar flows and aggregate massive number of mice flows into a few meta-flows. Compared with existing solutions, our approach dynamically aggregates large number of such small flows into fewer flows, based on traffic characteristics and access node preferences. Using this approach, we alleviate the problem of processing a large amount of micro flows, and also significantly improve the accuracy of meeting the access node QoS demands. We conducted experiments, using a dataset of up to 100,000 flows, and studied the performance of our algorithm analytically. The experimental results are presented to show the promising effectiveness and scalability of our proposed approach.

• 전기학회논문지P
• /
• 제60권3호
• /
• pp.150-154
• /
• 2011

The technology to build high speed network using low cost DSL in the areas where the cost to build high speed network is high and the network environment is not very accommodating is important in providing the high speed network that meets the user demand and utilizing the network resources in an efficient way. This study presents development of the link aggregation equipment that performs the access control and firewall functions for packet processing based LAN users. The equipments developed support up to 5 line link aggregation as opposed to current 2 line link aggregation. The equipments also allow the use of high speed network in the areas where the network environment is not very accommodating. Also, the fail-over function is added to each line to provide reliability and the self-security function is enhanced to protect the network from unauthorized use and prevents waste of network resources by authorized users.

• Journal of Mechanical Science and Technology
• /
• 제19권3호
• /
• pp.887-893
• /
• 2005

The aggregability of red blood cells (RBCs) was determined by laser backscattering light analysis in a microfluidic channel. Available techniques for RBC aggregation often adopt a rotational Couette-flow using a bob-and-cup system for disaggregating RBCs, which causes the system to be complex and expensive. A disposable microfluidic channel and vibration generating mechanism were used in the proposed new detection system for RBC aggregation. Prior to measurement, RBC aggregates in a blood sample were completely disaggregated by the application of vibration-induced shear. With the present apparatus, the aggregation indexes of RBCs can be measured easily with small quantities of a blood sample. The measurements with the present aggregometer were compared with those of LORCA and the results showed a strong correlation between them. The aggregability of the defibrinogenated blood RBCs is markedly lower than that of the normal RBCs. The noble feature of this design is the vibration-induced disaggregation mechanism, which can incorporate the disposable element that holds the blood sample.