• Proceeding of EDISON Challenge
• /
• 2015.03a
• /
• pp.70-75
• /
• 2015

Fasciclin 1 (FAS1) is an extracellular protein whose aggregation in cornea leads to visual impairment. While a number of FAS1 mutants have been studied that exhibit enhanced/decreased aggregation propensity, no structural information has been provided so far that is associated with distinct aggregation potential. In this study, we have investigated the structural and thermodynamic characteristics of the wild-type FAS1 and its two mutants, R555Q and R555W, by using molecular dynamics simulations and three-dimensional reference interaction site model (3D-RISM) theory. We find that the hydrophobic solvent accessible surface area increases due to hydrophobic core repacking in the C-terminus caused by the mutation. We also find that the solvation free energy of the mutants increases due to the enhanced non-native H-bonding. These structural and thermodynamic changes upon mutation contribute to understand the aggregation of these mutants.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.5 no.2
• /
• pp.344-358
• /
• 2011

Wireless tactical network (WTN) is the most important present-day technology enabling modern network centric warfare. It inherits many features from WMNs, since the WTN is based on existing wireless mesh networks (WMNs). However, it also has distinctive characteristics, such as hierarchical structures and tight QoS (Quality-of-Service) requirements. Little research has been conducted on hierarchical protocols to support various QoS in WMN. We require new protocols specifically optimized for WTNs. Control packets are generally required to find paths and reserve resources for QoS requirements, so data throughput is not degraded due to overhead. The fundamental solution is to adopt topology aggregation, in which a low tier node aggregates and simplifies the topology information and delivers it to a high tier node. The overhead from control packet exchange can be reduced greatly due to decreased information size. Although topology aggregation is effective for low overhead, it also causes the inaccuracy of topology information; thus, incurring low QoS support capability. Therefore, we need a new topology aggregation algorithm to achieve high accuracy. In this paper, we propose a new aggregation algorithm based on star topology. Noting the hierarchical characteristics in military and hierarchical networks, star topology aggregation can be used effectively. Our algorithm uses a limited number of bypasses to increase the exactness of the star topology aggregation. It adjusts topology parameters whenever it adds a bypass. Consequently, the result is highly accurate and has low computational complexity.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 2009.05a
• /
• pp.473-476
• /
• 2009

Frame Aggregation is a promissing technology for improving MAC throughput in IEEE 802.11n. In IEEE 802.11n, two frame aggregation schemes, Aggregate MSDU (A-MSDU) and Aggregate MPDU (A-MPDU), are defined. In this paper, we analyze the performance the two-level frame aggregation scheme where A-MSDU and A-MPDU are combined. We develop the analytical model for the two-level frame aggregation scheme and present numerical results on the effect of bit error rate, aggregation size, and the number of nodes.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.7 no.3
• /
• pp.490-508
• /
• 2013

One of the most important scalability issues facing the current Internet is the rapidly increasing rate of BGP updates (BGP churn), to which route flap and path exploration are the two major contributors. Current countermeasures would either cause severe reachability loss or delay BGP convergence, and are becoming less attractive for the rising concern about routing convergence as the prevalence of Internet-based real time applications. Based on the observation that highly active prefixes usually repeatedly explore very few as-paths during path exploration, we propose a router-level mechanism, Path Exploration Aggregation (PEA), to scale BGP without either causing prefix unreachable or slowing routing convergence. PEA performs aggregation on the transient paths explored by a highly active prefix, and propagates the aggregated path instead to reduce the updates caused by as-path changes. Moreover, in order to avoid the use of unstable routes, PEA purposely prolongs the aggregated path via as-path prepending to make it less preferred in the perspective of downstream routers. With the BGP traces obtained from RouteViews and RIPE-RIS projects, PEA can reduce BGP updates by up to 63.1%, shorten path exploration duration by up to 53.3%, and accelerate the convergence 7.39 seconds on average per routing event.

• Journal of the Semiconductor & Display Technology
• /
• v.15 no.1
• /
• pp.47-51
• /
• 2016

Human visual system infers 3D vision through stereo disparity in the stereoscopic images, and stereo visioning are recently being used in consumer electronics which has resulted in much research in the application field. Basically, stereo vision system consists of four processes, which are cost computation, cost aggregation, disparity calculation, and disparity refinement. In this paper, we present and evaluate the existing various methods, focusing on cost aggregation for stereo vision system to comparatively analyze the performance of their algorithms for a given set of resources. Experiments show that Normalized Cross Correlation and Zero-Mean Normalized Cross Correlation provide higher accuracy, however they are computationally heavy for embedded system in the real time systems. Sum of Absolute Difference and Sum of Squared Difference are more suitable selection for embedded system, but they should be required on improvement to apply to the real world system.

• Annual Conference on Human and Language Technology
• /
• 2019.10a
• /
• pp.155-160
• /
• 2019

본 연구에서는 사진 검색을 위한 Attentive Aggregation(주의적 종합) 기반의 언어-시각 크로스모달 임베딩 모델을 제안한다. 본 연구에서는 크로스모달 임베딩을 활용한 검색 과제에서 검색 대상의 임베딩을 계산하는 새로운 방법으로 '질의 기반 종합 검색 대상 임베딩'을 제안하며, Attentive Aggregation 레이어를 활용하여 이를 적용한 크로스모달 임베딩 모델을 제안한다. 제안 모델은 정보량이 많은 사진 데이터로부터 여러 특징을 추출한 뒤 주어진 질의에 따라 이들을 선택적으로 반영한 임베딩을 계산할 수 있으며, 이에 따라 Recall@10 약 0.23, MAP@10 약 0.11, MRR 약 0.13으로 Baseline과 비교하였을 때 크게 향상된 사진 검색 성능을 보였다.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.12 no.10
• /
• pp.4952-4975
• /
• 2018

An induced hesitant linguistic aggregation operator is investigated in the paper, in which, hesitant fuzzy linguistic evaluation values are associated with probabilistic information. To deal with these hesitant fuzzy linguistic information, an induced hesitant fuzzy linguistic probabilistic ordered weighted averaging (IHFLPOWA) operator is proposed, monotonicity, boundary and idempotency of IHFLPOWA are proved. Then andness, orness and the entropy of dispersion of IHFLPOWA are analyzed, which are used to characterize the weighting vector of the operator, these properties show that IHFLPOWA is extensions of the induced linguistic ordered weighted averaging operator and linguistic probabilistic aggregation operator. In this paper, IHFLPOWA is utilized to gather linguistic information and create fuzzy ontologies, and a movie fuzzy ontology as an illustrative case study is used to show the elaboration of the proposed method and comparison with the existing linguistic aggregation operators, it seems that the IHFLPOWA operator is an useful and alternative operator for dealing with hesitant fuzzy linguistic information with probabilistic information.

• Food Science and Biotechnology
• /
• v.16 no.2
• /
• pp.218-222
• /
• 2007

The anticoagulant properties of Cinnamomum cassia bark-derived materials were evaluated against platelet aggregation induced by arachidonic acid (AA), collagen, platelet activating factor (PAF), or thrombin, and these effects were then compared to those of three commercially available compounds (cinnamic acid, cinnamyl alcohol, and aspirin). The active constituent obtained from C. cassia barks was isolated by silica gel column chromatography and high pressure liquid chromatography (HPLC), and was characterized as trans-cinnamaldehyde by MS, $^1H-NMR$, $^{13}C-NMR$, and IR spectroscopy. With regard to 50% inhibitory concentration ($IC_{50}$) values, cinnamaldehyde was found to effectively inhibit platelet aggregation induced by AA ($IC_{50},\;43.2\;{\mu}M$) and collagen ($IC_{50},\;3.1\;{\mu}M$). By way of comparison, cinnamaldehyde proved to be a significantly more potent platelet inhibitor against platelet aggregation induced by collagen than aspirin. The effect exerted by cinnamaldehyde against platelet aggregation induced by AA was 1.2 times less than that of aspirin. These results indicate that cinnamaldehyde may prove useful as a lead compound for the inhibition of platelet aggregation induced by AA and collagen.

• Korean Chemical Engineering Research
• /
• v.56 no.1
• /
• pp.14-23
• /
• 2018

The effect of dodecylbenzene sulfonic acid (DBSA) with different addition amount of DBSA ($M_{DBSA}$), temperatures and solvent-to-oil ratio (SOR, v/v) on asphaltene aggregation in a solvent deasphalting system was investigated. Increasing the $M_{DBSA}$ at SOR 10 and $55^{\circ}C$ caused the asphaltene removal ratio (ARR) to increase first, then maximize at 1 wt% of $M_{DBSA}$ and then decrease continuously. Based on the SARA (saturate, aromatic, resin, asphaltene) composition, the adsorption amount of DBSA on the asphaltene surface and the self-aggregation of the DBSA, the reason for the change in ARR with $M_{DBSA}$ was found due to the adsorption mechanism. In addition, the asphaltene-resin-DBSA colloidal size confirmed the change of adsorption behavior between the asphaltene and DBSA. Based on the results of this study, a hypothetical adsorption mechanism of DBSA on asphaltene aggregation in the solvent deasphalting system was conceived of and proposed.

• Progress in Superconductivity and Cryogenics
• /
• v.20 no.2
• /
• pp.11-15
• /
• 2018

In this study, a cancer treatment by accumulating and aggregating ferromagnetic particles in newborn blood vessels was examined. It is necessary for this treatment to control dispersion-aggregation property of ferromagnetic particles. Ferromagnetic particles required in this method disperse at low magnetic field, aggregate at high magnetic field and maintain the aggregation even after removal of the magnetic field. In order to control the dispersion-aggregation property, the surface of magnetite particles was modified with higher fatty acids having different lengths. As a result, we succeeded to prepare propionic acid-modified magnetite particles that form irreversible aggregation by magnetic field. The model experiments simulating newborn blood vessels showed that these particles can block the flow by the magnetic field, and the blockage was maintained after removal of the magnetic field.