• Toxicological Research
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• 제16권3호
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• pp.195-200
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• 2000

Antidotal efficacy of physostigmine plus procyclidine, the combinational prophylactics for organophosphate poisoning, was evaluated in rats and guinea pigs. To assess the dose-response relation-ship in rats, various doses (0.3-6.0mg/kg) of procyclidine in combination with a fixed dose (0.1mg/kg) of physostigmine were pretreated subcutaneously 30 min prior to subcutaneous exposure to nerve-agents. Physostigmine alone exerted protection ratios of 2.44, 1.20, 1.50, 1.50 and 2.20 folds for tabun, sarin, soman, cyclosarin and V-agent, respectively. Interestingly, coadmnistration of procyclidine with physostigmine exhibited remarkable synergistic effects in a dose-dependent manner, leading to 4.00~8.00 folds for tabun, 2.15-8.50 folds for sarin, 1.92~507 folds for so man, 2.15~2.90 folds for cyclosarin, and 2.71~10.50 folds for V-agent. On the contrary, a low effect (l.65 fold) was achieved with the traditional antidotes atropine (17.4 mg/kg) plus 2-pralidoxime (30 mg/kg) treated immediately after soman poisoning. Noteworthy, the combinational prophylactics markedly potentiated the effect of atropine plus 2-pralidoxime to 6.13 and 12.27 folds with 1.0 and 3.0 mg/kg of procyclidine, respectively, against soman poisoning. In guinea pigs, the physostigmine plus procyclidine prophylactics exerted protective effects of 3.00~4.70 folds against soman intoxcation, which were much higher at low doses (0.3~1.0 mg/kg) of procyclidine than those in rats. Taken together, it is proposed that the combinational prophylactics composed oj physostigmine and procyclidine could be a promising antidote regimen for the poisoning with organophosphates possessing diverse properties.

• 한국멀티미디어학회논문지
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• 제19권3호
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• pp.595-602
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• 2016

With the evolution and development of many kinds of healthcare devices and techniques, u-health standards have emerged as a major issue. Yet, most legacy medical devices and systems are still being used without deployment of the standards. Therefore, it is required to support backward compatibility for u-health standard-compliant systems to communicate with legacy non-standard medical and healthcare devices. This paper proposes a new scheme to support backward compatibility of IEEE 11073 system by adding a codec module to IEEE 11073 agent. The codec converts data sent by non-standard health devices to IEEE 11073 MDER data. Plus, we implemented the proposed IEEE 11073 agent with an Intel Edison board which is one of popular open source H/W platforms. The IEEE 11073 manager of the proposed system can monitor and control legacy non-standard devices through the proposed agent system. In our experimental results, we examined the proposed system can support interoperability between u-health standard and non-standard devices and contribute to the growth and expansion of u-health services.

• International Journal of Fuzzy Logic and Intelligent Systems
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• 제4권1호
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• pp.29-33
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• 2004

I propose a personalized digital library system (PDLS) based on an advanced distributed agent platform. The new platform is developed by improving the DECAF (Distributed Environment-Centered Agent Framework) which is one of the conventional distributed agent development toolkits. Also, a mobile ORB (Object Request Broker), Voyager, and a new multi agent negotiation algorithm are adopted to develop the advanced platform. The new platform is for mobile multi agents as well as the distributed environment, whereas the DECAF is for the distributed and non-mobile environment. From the results of the simulation the searched time of PDLS is lower, as the numbers of servers and agents are increased. And the user satisfaction is four times greater than the conventional client-server model. Therefore, the new platform has some optimality and higher performance in the distributed mobile environment.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2001년도 ICCAS
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• pp.25.2-25
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• 2001

This paper describes a mobile robot intended for being employed in a multi-agent system. We have already proposed a multi-agent system which realizes patient-aid by helping a lying patient take a distant object on the table. In this paper, a mobile robot agent is developed and is included in the system. An effective man-machine communication strategy is proposed by use of a vision agent settled on the ceiling. If a human (assumed to be a patient) wishes to take an object distant on the floor, he points to the object. The vision agent detects the direction of his arm by image processing and guesses which object he intends to take. The vision agent asks him if it is what he wants and, if yes, the mobile robot runs to take and bring it to him. The system is overviewed with the explanation of a mobile robot. Some experimental results are shown with discussion.

• 한국CDE학회논문집
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• 제3권1호
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• pp.31-39
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• 1998

This paper deals with a development of the system that implements a collaborative design environment with some intelligent agents on the m. Intelligent agents can design collaboratively trough an interchange of messages in their special domains. Such a collaborative design of agents is achieved on the WWW. In this paper, we propose special agents named intercessor and DCM (Dynamic Connection Manager) and suggest new connection architecture using these agents in the WWW in order to improve the pre-existed agent connection architecture. The proposed agents are developed using Java language and JATLite API. We apply the these agents to the new architecture and show some possibilities that the agent connection architecture can be extended in the WWW Agents interchange messages with others using KOML (Knowledge Query and Manipulation Language), agent communication protocol and language, and deal with message autonomously according to their rule base. Agents register and connect dynamically trough the intercessor agent, and infer from their.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2002년도 하계학술대회 논문집 A
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• pp.193-195
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• 2002

In this paper, a communication module is proposed to be applied to communication between over current relay (OCR) agents in multi agent protection system. A multi agent system can achieve a global goal beyond the ability of each individual agent by working together, in which it is the prerequisite for each agent to be able to exchange or share information or processing status with other agent. The proposed communication module is purposed to enable not only each agent to bring about its own goal, but also the whole protective system to provide much improved coordinated protection. It is applied to a self adaptive protection system for a distribution network using multi agent concept to show its effectiveness.

• 한국콘텐츠학회:학술대회논문집
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• 한국콘텐츠학회 2006년도 춘계 종합학술대회 논문집
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• pp.503-506
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• 2006

본 논문에서는 다양한 학술정보들을 수집, 분석, 처리 및 관리가 이루어지는 학술정보유통 에이전트 시스템을 제안한다. 일반적으로 학술정보를 수집하여 이를 서비스하기 위한 절차는 대부분 유사하게 처리되나, 데이터의 특성과 운용하고 있는 하드웨어와 소프트웨어 종류에 따라 같은 내용임에도 다른 내용으로 가공되기도 한다. 또한, 정보를 가공하는데 있어 오프라인 작업이 발생되는 경우 처리 인력 및 시간에 많은 소요가 되기 때문에 최신의 정보를 빨리 제공하는데 어려움이 있다. 이에, 데이터에 독립적이면서도 모든 데이터를 수용할 수 있는 학술정보유통프레임워크의 설계와 개발이 중요한 요소가 되며, 또한 프레임워크에 적용된 에이전트 시스템은 인력 및 시간 절감뿐만 아니라 시스템의 확장성 및 유연성을 보장하며, 양질의 정보서비스 제공이 가능할 것으로 기대한다. 학술정보유통 에이전트 시스템은 원시자료형식 등록 에이전트(Resource Format Register Agent), 자료 수집 에이전트(Data Collector Agent), 자료 분석 에이전트(Data Analyzer Agent), 자료처리 에이전트(Data Processor Agent), 데이터베이스적재 에이전트(MetaDB Creator Agent)의 멀티에이전트로 구성된다. 본 논문은 에이전트 시스템이 수행하는 필수적인 기능과 요소에 대해 설명한다.

• 한국시뮬레이션학회논문지
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• 제17권2호
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• pp.91-103
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• 2008

자동화 제조 시스템에 시뮬레이션 기법을 사용하기 인해서는 자재취급 시스템의 성과를 동적으로 측정해야만 한다. 다중 에이전트 기술은 제조시스템을 지능화 시키고, 분산처리 된 시뮬레이터 개발에 적합하다. 다중 에이전트 시스템은 하나의 조정 에이전트와 다수의 응용 에이전트들로 구성된다. AGVS 시뮬레이터에 있어 이슈는 운반차량의 대수 결정, 양단방향 흐름에서의 이동경로 결정등과 같은 set-up문제와 운영문제로 구분 지을 수 있다. 본 논문에서는 다중 에이전트 기술을 사용하고, 실시간 교착상태 해법 알고리즘이 포함된 시뮬레이터를 소개한다. 시뮬레이터는 잘 알려진 프로이드(Floyd) 알고리즘을 사용하여 AGVS의 최단 이동경로를 구성된다. 움직이고 있는 차량 에이전트는 조정 에이전트에 의해 실시간 제어로 작동되고, AGV는 경로확인 알고리즘을 사용하여 충돌과 교착상태를 피한다. AGV의 위치는 수평시간 계획법에 근거하여 동적으로 재계산된다. 충돌해소 알고리즘은 어떠한 배치 형태에서라도, 그리고 큰 규모의 문제에서도 AGVS의 운영 중의 주행문제 해결을 보장한다. 시뮬레이터는 AGV들의 AGVS 칸트차트를 통하여 작동정보를 받고, 표현한다. 제안된 알고리즘의 성과와 다중 에이전트 기술을 사용하여 개발한 시뮬레이터는 실험을 통하여 검증된다.

• Asia pacific journal of information systems
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• 제12권4호
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• pp.193-213
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• 2002

The sales activity of most of small manufacturing companies is based on orders of buyers. The process of promotion, negotiation, receipt and selection of orders of the manufacturers is closely coupled with the load status of the production lines. The decision on whether to accept an order or not, or the selection of optimal order set among excessive orders is entirely dependent on the schedule of production lines. However, in the real world, since the production scheduling activity is mainly performed by human experts, most of small manufacturers are suffer from being unable to meet due dates, lack of rapid decision on the acceptance of new order. Recently, Internet based Electronic Commerce is recognized as one of the alternatives for strengthening sales power of small and medium companies. However, small and medium manufacturers can't adjust properly to the new environment because they are in short of money, personnel, and technology. To cope with this problem, this paper deals with development of part sales agent coupled with virtual manufacturing in Internet environment that consist of selection agent, advertisement agent, selection agent, negotiation agent, and virtual manufacturing system. This paper develops a time-bounded negotiation mechanism for small and medium manufacturers in agent-based automated negotiation between customers and negotiation agents. Furthermore, to select optimal order set maximized profit, we first formulate the order selection problem with mixed integer programming, but the computation time of IP is not acceptable for real world scale problem. To overcome this problem and dynamic nature of virtual manufacturing, we suggest a genetic algorithm approach, which shows a reasonable computation time for real world case and good incremental problem solving capability.

• 한국산학기술학회논문지
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• 제17권4호
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• pp.296-302
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• 2016

콘크리트의 내구성 저하로 인한 균열의 보수 및 보강에 소요되는 비용은 콘크리트 구조물의 유지비용 증대로 연결되어 균열발생 저감에 대한 연구가 요구되고 있다. 특히, 전력공급용 시설인 전력구의 경우 지하 매설물이므로 보수 및 보강은 경제적으로 큰 부담이 된다. 그러므로 지하매설 전력구의 경우 효과적인 균열 저감 방안이 설계 초기단계부터 요구되어진다. 본 연구는 전력구용 저수축 콘크리트 제조를 위한 수축저감제 개발의 일환으로 수축저감제 사용 콘크리트의 초기 강도 개선을 위해 TEA를 검토하였다. 검토결과, TEA를 수축저감제의 3% 사용할 경우 조기 강도가 크게 개선되었으며, 수축저감 효과도 우수한 것으로 확인되었다. 또한, TEA 3 %에 수축저감제 2.0 % 혼합하여 적용하였을 경우 압축강도 특성 및 건조수축 길이변화 실험결과에서 가장 우수한 것으로 나타나 수축저감제로서의 가능성을 확인하였다. 추후 수축저감제의 범용적인 적용성 검토를 위하여 수축저감제의 사용재료 변화 등에 대한 다양한 재료변수 요인 검토를 통하여 수축저감제의 성능 검토가 필요할 것으로 사료된다.