• Title/Summary/Keyword: Adverse Factors

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Analysis of Factors Affecting Medication Compliance of Outpatients (의료기관 외래 이용자의 복약순응 관련 요인분석)

  • Lee, Eui-Kyung;Park, Jeong-Young
    • Quality Improvement in Health Care
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    • v.9 no.2
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    • pp.164-175
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    • 2002
  • Background : The purpose of this study was to investigate the current status of medication compliance of outpatients and to analyze the factors contributing to medication non-compliance Methods : Telephone survey was conducted to the 1,000 outpatients who visited medical institutions during the period from January 2002 to April 2002. Subjects were randomly selected from the telephone directories of the nation, and the socio-demographic characteristics of the respondents such as age, gender and region were matched based on those of outpatients in 2001. Results : The results of survey revealed that those who complied with doctors' regimen in the right way accounted for 82.4%. The compliance increased with the strong belief in the medication, less unwanted side effects and inconvenience, more severity of disease, and lower perceived health status. Compliance rate was also higher in the patients group who experienced the drug education by the pharmacists than those who did not. Conclusion : In order to improve drug compliance, drug information on efficacy, adverse reaction, drug interactions, and basic disease information are to be provided to the patients. Drug education needs to be focused not only on providing knowledge of drugs and diseases but also changing attitude on drug use of the patients.

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A Study on the Quests of 'Warlords of Draenor' in the Game, World of Warcraft (World of Warcraft '드레노어의 전쟁군주' 퀘스트 연구)

  • Lee, Jae Hong
    • Journal of Korea Game Society
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    • v.16 no.4
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    • pp.105-114
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    • 2016
  • This study analyzed a total of 1,025 quests in the 'Warlords of Draenor' which is the fifth expansion set to the massively multiplayer online role-playing game (MMORPG) World of Warcraft, by dividing them into violent and nonviolent quests. There was a total of 515 nonviolent quests which can be categorized into 46 types and a total of 510 violent quests that can be categorized into 7 types. The balance between violent and nonviolent quests shows that the game makers limited the number of adverse factors that can cause the players to be excessively absorbed in the game while successfully incorporating factors that can have positive effect on game players.

Development of a Leading Performance Indicator from Operational Experience and Resilience in a Nuclear Power Plant

  • Nelson, Pamela F.;Martin-Del-Campo, Cecilia;Hallbert, Bruce;Mosleh, Ali
    • Nuclear Engineering and Technology
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    • v.48 no.1
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    • pp.114-128
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    • 2016
  • The development of operational performance indicators is of utmost importance for nuclear power plants, since they measure, track, and trend plant operation. Leading indicators are ideal for reducing the likelihood of consequential events. This paper describes the operational data analysis of the information contained in the Corrective Action Program. The methodology considers human error and organizational factors because of their large contribution to consequential events. The results include a tool developed from the data to be used for the identification, prediction, and reduction of the likelihood of significant consequential events. This tool is based on the resilience curve that was built from the plant's operational data. The stress is described by the number of unresolved condition reports. The strain is represented by the number of preventive maintenance tasks and other periodic work activities (i.e., baseline activities), as well as, closing open corrective actions assigned to different departments to resolve the condition reports (i.e., corrective action workload). Beyond the identified resilience threshold, the stress exceeds the station's ability to operate successfully and there is an increased likelihood that a consequential event will occur. A performance indicator is proposed to reduce the likelihood of consequential events at nuclear power plants.

Vasovagal Syncope before General Anesthesia in a Patient with Alveolar Bone Deficiency on Maxilla and Mandible (상하악 치조골 결손 환자에서 전신 마취 전 발생한 혈관미주신경성 실신)

  • Yoon, Sang-Yong;Young, Yoon-Ji;Kim, Cheul-Hong
    • Journal of The Korean Dental Society of Anesthesiology
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    • v.11 no.2
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    • pp.159-163
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    • 2011
  • Vasovagal syncope accounts for the majority of adverse events that occur in dental offices and is normally related to emotional or somatic factors. The factors trigger intense parasympathetic state, leading to bradycardia and hypotension. We experienced a case of vasovagal syncope just before general anesthesia. A 49-year-old woman with alveolar bone deficiency on maxilla and mandible was planned to undergo an alveolar bone graft with mandibular body under general anesthesia. She didn't have any histories of disease, medication or syncope. Though she showed a little anxiety from admission, she had no pre-operative medication. After she was guided to the operating room, she had signs and symptoms of vasovagal syncope without any prodromes. The patient was resuscitated soon only by the conservative treatment and was operated under general anesthesia.

Deformation and failure mechanism exploration of surrounding rock in huge underground cavern

  • Tian, Zhenhua;Liu, Jian;Wang, Xiaogang;Liu, Lipeng;Lv, Xiaobo;Zhang, Xiaotong
    • Structural Engineering and Mechanics
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    • v.72 no.2
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    • pp.275-291
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    • 2019
  • In a super-large underground with "large span and high side wall", it is buried in mountains with uneven lithology, complicated geostress field and developed geological structure. These surrounding rocks are more susceptible to stability issues during the construction period. This paper takes the left bank of Baihetan hydropower station (span is 34m) as a case study example, wherein the deformation mechanism of surrounding rock appears prominent. Through analysis of geological, geophysical, construction and monitoring data, the deformation characteristics and factors are concluded. The failure mechanism, spatial distribution characteristics, and evolution mechanism are also discussed, where rock mechanics theory, $FLAC^{3D}$ numerical simulation, rock creep theory, and the theory of center point are combined. In general, huge underground cavern stability issues has arisen with respect to huge-scale and adverse geological conditions since settling these issues will have milestone significance based on the evolutionary pattern of the surrounding rock and the correlation analyses, the rational structure of the factors, and the method of nonlinear regression modeling with regard to the construction and development of hydropower engineering projects among the worldwide.

The Positive Effects of Corporate Reading Management on Employee Performance

  • JUNG, Sung-Hyun;AHN, Byoung-Soon
    • East Asian Journal of Business Economics (EAJBE)
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    • v.10 no.4
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    • pp.55-64
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    • 2022
  • Purpose - Corporate reading management requires employees capable of doing their job since employee performance is crucial to the firm's profitability. The objective of this study was to evaluate the positive effects of corporate reading management on employee management. It focuses on factors increasing employee productivity and the impacts corporate management brings about on the overall productivity of any kind of company. Research design, Data, and methodology - The current authors have investigated and conducted the qualitative content analysis (QCA) to obtain the adequate textual dataset in the prior and current literature. One of the primary benefits of doing research using content analysis is that it enables the researcher to employ a combination of qualitative and quantitative research methodologies. Result - Based on the review of the prior literature, the present authors found that there are four corporate reading management solutions to improve employee performance, following those instructions - A. Increased Motivation and Productivity, B. Employee Development, C. Businesses' Objective Alignment, and D. Improved Work Environment. Conclusion - This study addressed and figured out different factors that reading corporate can apply to influence employee performance, thus increasing the company's productivity. Future research should evaluate the adverse effects businesses might face from unfavorable working environments. The research also needed to address how ethics influences employee performance.

The Impact of the Working Environment and Welfare on Human Resources Maintenance: An Empirical Study in Vietnam

  • KHANH, Vo Thi Van
    • The Journal of Asian Finance, Economics and Business
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    • v.8 no.6
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    • pp.447-453
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    • 2021
  • Human resources play a key role in developing and enhancing the manner in which an organization change. In fact, the role of human resource-related quality management has contributed greatly to the growth of the organization in both the short and long term. The purpose of the current study is to identify factors that influence human resource retention in Hanoi in the backdrop of growing economic performance of Hanoi in Vietnam's economy. Primary data was collected through questionnaires of 280 respondents from the four districts in Hanoi, including 25.2% of respondents working in Cau Giay district, 21.2% in Dong Da district, 34.2% in Ha Dong district, and 19.4% in Thanh Xuan district. After applying Cronbach's Alpha and Explore Factor Analysis (EFA) analysis, Durbin-Watson test, empirical results demonstrate that relationship among co-workers has a significant and positive contribution on the maintenance of human resources in the organization. Additionally, higher welfare facilities for an employee are more likely to impact the maintenance of human resources in the organization. Factors such as working environment, job placement, and leadership relationship have no adverse effect on the maintenance of human resources, although a positive impact could be established in all cases.

KLF9 deficiency protects the heart from inflammatory injury triggered by myocardial infarction

  • Zhihong Chang;Hongkun Li
    • The Korean Journal of Physiology and Pharmacology
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    • v.27 no.2
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    • pp.177-185
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    • 2023
  • The excessive inflammatory response induced by myocardial infarction exacerbates heart injury and leads to the development of heart failure. Recent studies have confirmed the involvement of multiple transcription factors in the modulation of cardiovascular disease processes. However, the role of KLF9 in the inflammatory response induced by cardiovascular diseases including myocardial infarction remains unclear. Here, we found that the expression of KLF9 significantly increased during myocardial infarction. Besides, we also detected high expression of KLF9 in infiltrated macrophages after myocardial infarction. Our functional studies revealed that KLF9 deficiency prevented cardiac function and adverse cardiac remodeling. Furthermore, the downregulation of KLF9 inhibited the activation of NF-κB and MAPK signaling, leading to the suppression of inflammatory responses of macrophages triggered by myocardial infarction. Mechanistically, KLF9 was directly bound to the TLR2 promoter to enhance its expression, subsequently promoting the activation of inflammation-related signaling pathways. Our results suggested that KLF9 is a pro-inflammatory transcription factor in macrophages and targeting KLF9 may be a novel therapeutic strategy for ischemic heart disease.

The Impact of Ultra-Processed Food Consumption on Health (초가공식품 섭취가 건강에 미치는 영향)

  • Ha Eun Ryu;Min-Young Nam;Yu-Jin Kwon
    • Archives of Obesity and Metabolism
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    • v.3 no.1
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    • pp.14-26
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    • 2024
  • Ultra-processed foods, falling under group 4 of the Nova classification system, are manufactured from processed food ingredients such as oils, fats, sugars, starch, and protein isolates, containing minimal to no whole food. They commonly incorporate flavorings, colorings, emulsifiers, and various cosmetic additives to enhance their palatability. Ultra-processed foods have become increasingly prevalent in contemporary society owing to their convenience, affordability, extended shelf life, and enhanced taste and aroma through additives. This surge in the consumption of ultra-processed foods has sparked discussions regarding its adverse health effects. Numerous studies have highlighted that an increased intake of ultra-processed foods elevates the risk of metabolic disorders, such as cardiovascular diseases, obesity, and diabetes, along with an increased risk of various cancers. Moreover, its association with an increased mortality risk underscores the importance of recognizing that opting for these foods based solely on taste and convenience is risky. Thus, by recognizing dietary habits as modifiable factors that can prevent health issues, maintaining a balanced diet with diverse nutrient intakes is crucial for overall health. Therefore, raising awareness and understanding of ultra-processed food consumption can significantly contribute to promoting healthy lifestyles.

A Case of Acute Pulmonary Thromboembolism after Taking Tadalafil

  • Lee, Jinwoo;Kwon, Ji Hyun;Lee, Chang-Hoon;Lee, Sang-Min;Yim, Jae-Joon;Yoo, Chuy-Gyu;Kim, Young Whan;Han, Sung Koo;Park, Young Sik
    • Tuberculosis and Respiratory Diseases
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    • v.73 no.4
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    • pp.231-233
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    • 2012
  • Tadalafil is a phosphodiesterase-5 inhibitor (PDE5I), which is widely used to treat erectile dysfunction. Although PDE5Is have excellent safety profiles, and most of the side effects are mild, rare serious adverse events have been reported in association with PDE5Is. Thrombosis is one of those events, and a few previous reports have suggested the association of PDE5Is with thrombosis. We report the case of a 61-year-old male who developed pulmonary embolism combined with pulmonary infarction directly after taking tadalafil. Both the patient and the physician suspected tadalafil as the culprit drug, as the patient was in an otherwise healthy condition. However, after extensive evaluation, we noticed that factor VIII levels were elevated. Prior reports suggesting the association between thrombosis and PDEIs either lack complete information on coagulation factors, or show inconsistencies in their results. Physicians should operate caution prior to accepting the diagnosis of adverse drug reaction.