• Title/Summary/Keyword: Adverse Event

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Soil Erosion Modeling in the 3S Basin of the Mekong River Basin

  • Thuy, Hoang Thu;Lee, Giha;Yu, Wansik;Shin, Yongchul
    • Journal of the Korean GEO-environmental Society
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    • v.18 no.7
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    • pp.21-35
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    • 2017
  • The 3S Basin is described as an important contributor in terms of many aspects in the Mekong River Basin in Southeast Asia. However, the 3S Basin has been suffering adverse consequences of changing discharge and sediment, which are derived from farming, deforestation, hydropower dam construction, climate change, and soil erosion. Consequently, a large population and ecology system that live along the 3S Basin are seriously affected. Accordingly, the calculating and simulating discharge and sediment become ever more urgent. There are many methods to simulate discharge and sediment. However, most of them are designed only during a single rainfall event and they require many kinds of data. Therefore, this study applied a Catchment-scale Soil Erosion model (C-SEM) to simulate discharge and sediment in the 3S Basin. The simulated results were judged with others references's data and the observed discharge of Strung Treng station, which is located in the mainstream and near the outlet of the 3S Basin. The results revealed that the 3S Basin distributes 31% of the Mekong River Basin's total discharge. In addition, the simulated sediment results at the 3S Basin's outlet also substantiated the importance of the 3S Basin to the Mekong River Basin. Furthermore, the results are also useful for the sustainable management practices in the 3S Basin, where the sediment data is unavailable.

Effect of Dividend Policy on the New Issue Announcement Effects (배당정책에 따른 유상증자 공시효과)

  • Lee, Young-Hwan;Yoon, Hong-Geun;Ahn, Byung-Hwa
    • Journal of Digital Convergence
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    • v.12 no.3
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    • pp.149-160
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    • 2014
  • This paper analyses whether change in corporate dividend policy affects the new issue announcement effects. By conducting an event study using 683 new equity announcements data from year 2000 to year 2009, we find firms paying more dividends experience relatively negative announcement effects of seasoned equity offerings comparing with firms paying less dividend. The cross sectional regression analysis results confirm our findings. These results indicate that corporate dividend policy change may interact with forthcoming new equity announcement decision, which may result in a negative signal to the capital markets.

Case Series Report on the Effect of Hand Acupuncture - Focusing on 29 Patients with Headache -

  • Sun, Seung-Ho
    • Journal of Pharmacopuncture
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    • v.14 no.3
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    • pp.91-97
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    • 2011
  • Objectives : The purpose of 29 case series is to report the possibility that a hand acupuncture is effective in relieving headache. Methods : After approval from the Institutional Review Board (IRB), I analyzed 29 cases medical records of outpatients with headache, who visited ${\bigcirc}{\bigcirc}$ oriental medical hospital from December 2008 to December 2010, who have taken a hand acupuncture's treatment without other intervention, and who were diagnosed with one disease of international classification of headache disease second version (ICHD-2). The data was analyzed with Wilcoxon signed rank test to determine whether a hand acupuncture's treatment differed between before and after treatment's Visual Analogue Scale(VAS) according to types of headache and syndrome differentiation. Statistics program was used SPSS 18.0. Differences were considered significant at P<0.05. Results : The VAS of patients with headache was reduced after treatment of hand acupuncture from $6.57{\pm}2.04$ to $2.90{\pm}2.04$ for overall headache, from $6.32{\pm}2.05$ to $2.47{\pm}2.03$ for tension-type headache(P<0.001), from $7.10{\pm}2.18$ to $3.70{\pm}1.77$ for migraine(P<0.001), and from $6.00{\pm}1.41$ to $2.50{\pm}3.54$ for headache unspecified. A hand acupuncture produced a decrease in VAS of both ascendant hyperactivity of liver yang(P<0.001) and phlegm turbidity according to syndrome differentiation(P=0.002). No adverse event were encountered in any of the patients. Conclusions : It is suggested that a hand acupuncture may be effective in relieving headache, and could be applicable to first choice of acupuncture treatment for headache.

Infection with Mycobacterium tuberculosis Complicating an Intralobar Pulmonary Sequestration - A case report - (내엽성 폐분리증에서 발생한 결핵 감염 - 1예 보고 -)

  • Kim, Si-Wook;Hong, Jong-Myeon
    • Journal of Chest Surgery
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    • v.42 no.6
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    • pp.792-795
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    • 2009
  • Pulmonary sequestration is a relatively rare malformation. Infection with common pyogenes is a frequent complication in this disease. We report here on a case of intralobar sequestration that was infected with Mycobacterium tuberculosis in the absence of any other site of tuberculous infection. A 40-year man presented with a small amount of hemoptysis, and the man had been previously diagnosed with bronchiectasis 3 years ago. Chest computerized tomography revealed bronchiectasis with pneumonia in the left lower lobe and there was a large feeding artery from the thoracic aorta. A lobectomy of the left lower lobe was conducted via thoracotomy and the final pathologic examination confirmed pulmonary tuberculosis limited to the intralobar sequestrated lung. The patient underwent anti-tuberculous chemotherapy from the postoperative $7^{th}$ day and he was discharged without any adverse event.

Pectoralis Muscle Flap Repair Reduces Paradoxical Motion of the Chest Wall in Complex Sternal Wound Dehiscence

  • Zeitani, Jacob;Russo, Marco;Pompeo, Eugenio;Sergiacomi, Gian Luigi;Chiariello, Luigi
    • Journal of Chest Surgery
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    • v.49 no.5
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    • pp.366-373
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    • 2016
  • Background: The aim of the study was to test the hypothesis that in patients with chronic complex sternum dehiscence, the use of muscle flap repair minimizes the occurrence of paradoxical motion of the chest wall (CWPM) when compared to sternal rewiring, eventually leading to better respiratory function and clinical outcomes during follow-up. Methods: In a propensity score matching analysis, out of 94 patients who underwent sternal reconstruction, 20 patients were selected: 10 patients underwent sternal reconstruction with bilateral pectoralis muscle flaps (group 1) and 10 underwent sternal rewiring (group 2). Eligibility criteria included the presence of hemisternum diastases associated with multiple (${\geq}$3) bone fractures and radiologic evidence of synchronous chest wall motion (CWSM). We compared radiologically assessed (volumetric computed tomography) ventilatory mechanic indices such as single lung and global vital capacity (VC), diaphragm excursion, synchronous and paradoxical chest wall motion. Results: Follow-up was 100% complete (mean $85{\pm}24months$). CWPM was inversely correlated with single lung VC (Spearman R=-0.72, p=0.0003), global VC (R=-0.51, p=0.02) and diaphragm excursion (R=-0.80, p=0.0003), whereas it proved directly correlated with dyspnea grade (Spearman R=0.51, p=0.02) and pain (R=0.59, p=0.005). Mean CWPM and single lung VC were both better in group 1, whereas there was no difference in CWSM, diaphragm excursion and global VC. Conclusion: Our study suggests that in patients with complex chronic sternal dehiscence, pectoralis muscle flap reconstruction guarantees lower CWPM and greater single-lung VC when compared with sternal rewiring and it is associated with better clinical outcomes with less pain and dyspnea.

Clinical efficacy of chloroquine versus artemether-lumefantrine for Plasmodium vivax treatment in Thailand

  • Krudsood, Srivicha;Tangpukdee, Noppadon;Muangnoicharoen, Sant;Thangchartwet, Vipa;Luplertlop, Nutthanej;Srivilarit, Siripan;Wilairatana, Polrat;Kano, Shigeyuki;Ringwald, Pascal;Looareesuwan, Sornchai
    • Parasites, Hosts and Diseases
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    • v.45 no.2 s.142
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    • pp.111-114
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    • 2007
  • Chloroquine remains the drug of choice for the treatment of vivax malaria in Thailand. Mixed infections of falciparum and vivax malaria are also common in South-East Asia. Laboratory confirmation of malaria species is not generally available. This study aimed to find alternative regimens for treating both malaria species by using falciparum antimalarial drugs. From June 2004 to May 2005, 98 patients with Plasmodium vivax were randomly treated with either artemether-lumefantrine (n = 47) or chloroquine (n = 51). Both treatments were followed by 15 mg of primaquine over 14 days. Adverse events and clinical and parasitological outcomes were recorded and revealed similar in both groups. The cure rate was 97.4% for the artemether-lumefantrine treated group and 100% for the chloroquine treated group. We concluded that the combination of artemether-lumefantrine and primaquine was well tolerated, as effective as chloroquine and primaquine, and can be an alternative regimen for treatment of vivax malaria especially in the event that a mixed infection of falciparum and vivax malaria could not be ruled out.

Impact of Indirect Trauma via Media on Post-Traumatic Stress Symptoms : Online Survey Study (미디어 노출에 의한 간접외상이 외상 후 스트레스 증상에 미치는 영향 : 온라인 설문 조사 연구)

  • Park, Sang Eui;Jung, Youji;Lee, Jung Hyun
    • Anxiety and mood
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    • v.14 no.2
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    • pp.71-79
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    • 2018
  • Objective : Several earlier studies have reported similar symptoms in patients with posttraumatic stress disorder (PTSD) who have been repeatedly exposed to relevant media after disasters and trauma. This study aimed to examine the effects of indirect trauma experience through media rather than direct traumatic events on an individual's social life. Methods : Five hundred and fifty-four individuals participated in our online, self-reported questionnaire survey. All subjects were asked to complete a demographic questionnaire, Posttraumatic Diagnostic Scale, Beck Depression Inventory, the Impact of Event Scale-Revised, State-Trait Anxiety Inventory, Korean version of Alcohol Use Disorder Identification Test, Patient Health Questionnaire-15, Suicidal Behaviors Questionnaire-Revised. Participants were assessed in regards to their experience of violent media exposure within the past three months. Results : Data from our study indicates that the group exposed to violent media had significantly higher perceived stress, physical symptoms, insomnia, and suicide ideation in comparison to the control group. Among the major symptoms of PTSD, the proportion of intrusion symptoms was relatively high in the media exposed group. Conclusion : This suggests that indirect trauma caused by media exposure could cause post-traumatic stress symptoms. The PTSD caused by indirect trauma may have slight differences from the PTSD caused by direct trauma. Therefore, it is necessary to understand, prevent, and control the adverse effects of media.

A Case of Refractory Vitiligo Treated with Non-cultured Epidermal Cell Suspension Transplantation Using Suction Blister Method (흡입수포를 이용한 비배양표피세포이식술로 치료한 난치성 백반증 1예)

  • Eun, Sung Hye;Jung, Yu Seok;Lee, Hanna;Lee, Ji Hae;Kim, Gyong Moon;Bae, Jung Min
    • Korean journal of dermatology
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    • v.56 no.9
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    • pp.552-555
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    • 2018
  • Vitiligo is a commonly acquired cutaneous depigmentation disorder that affects 0.5~1% of the population worldwide. While phototherapy is the primary treatment for vitiligo, surgical methods can be used for treating patients who are refractory to conventional treatments. Herein, we present the case of a 14-year-old Korean girl who developed vitiligo after hematopoietic stem cell transplantation for the treatment of acute lymphoblastic leukemia. She had multiple depigmented patches on her lower legs that did not respond to narrow-band ultraviolet B phototherapy for 7 months. The depigmented patches were successfully treated by transplantation of non-cultured epidermal cell suspension from the epidermal roof of the suction blister in the right inner thigh. No adverse event, such as secondary infection or scarring in both the donor and recipient sites, was noted. We recommended that non-cultured epidermal cell suspension transplantation using the suction blister method would be a safe and effective option for the treatment of refractory vitiligo.

Associations of Ambient Air Pollutant Concentrations With Respiratory Symptoms and Perceived Health Status in Japanese Adults With and Without Chronic Respiratory Diseases: A Panel Study

  • Nakao, Motoyuki;Yamauchi, Keiko;Mitsuma, Satoshi;Odaira, Tetsuro;Obata, Hideto;Chijimatsu, Yoichi;Ishihara, Yoko
    • Journal of Preventive Medicine and Public Health
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    • v.52 no.6
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    • pp.416-426
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    • 2019
  • Objectives: In recent years, transboundary air pollution from mainland East Asia has led to growing concerns about air pollution in Japan. Air pollution is reportedly associated with the exacerbation of respiratory diseases. In this study, we assessed the effects of air pollution on respiratory symptoms and the health status of participants with and without chronic respiratory diseases. Methods: Participants (n=2753) with and without chronic respiratory diseases who visited healthcare facilities in Japan during February from 2010 to 2015 filled out a self-report questionnaire regarding their symptoms and perceived health status. Participants were followed up during April-May and June-July. Results: Oxidant concentrations were associated with respiratory symptoms, overall health, and quality of life (QoL). Suspended particulate matter (SPM) and particulate matter <$2.5{\mu}m$ levels were associated with physical fitness; SPM was also associated with QoL. Recent experience of an Asian sand dust event had a significant effect on allergic symptoms, change in health, and QoL. Conclusions: Respiratory symptoms were more strongly affected by oxidants than by other pollutants. Significant associations of air pollutants were found with a comprehensive range of items related to perceived health status, including overall health and QoL. Although the effects of air pollutants on respiratory symptoms and health status were more apparent among patients with respiratory diseases, the adverse effects of air pollutants were significant even among participants without such conditions.

Effects of Acupotomy and Selective Cryolysis including Herbal Medicine Treatment on Thigh Circumference: Case Series (한약치료를 포함한 도침치료와 냉각요법이 허벅지둘레에 미치는 영향: 증례군보고)

  • Cho, Kyongha;Yun, Younghee;Kim, Byeongtaek;Kim, Yoonsik;Choi, Ye-yong;Yoon, Sang-Hoon
    • Journal of Korean Medicine for Obesity Research
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    • v.17 no.2
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    • pp.133-139
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    • 2017
  • The aim of this study is to investigate the combined effect of acupotomy, selective cryolysis and herbal medicine therapy for treating regional fat accumulation of thigh. Twenty-four patients were selected for the study. A session of selective cryolysis and acupotomy treatments were performed on both thighs once a week, for four weeks, with administration of herbal medicine. Thigh circumference, weight, body mass index (BMI), skeletal muscle mass, and body fat rate were measured before and after the procedure. Statistical significance (P<0.05) was determined using the paired t-test. After treatments, thigh circumference was significantly reduced by $3.57{\pm}1.41cm$ in 4 weeks (P<0.001). Weight, BMI, skeletal muscle mass, and body fat rate too were significantly reduced (P<0.001). Of the 24 patients, 1 reported an adverse event of frostbite. We assume this combined therapy can be useful when dealing with localized fat accumulation. Long-term evaluation and further studies are required to identify the specific effect size.