• Title/Summary/Keyword: Advanced technology

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The Study on Tissue-Cultured Echinacea purpurea Adventitious Roots Extract for Application as a Cosmetic Ingredient (조직 배양한 에키네시아 추출물에 관한 효능 연구)

  • Park, Chang-Min;Joung, Min-Seok;Choi, Jong-Wan;Paek, Kee-Yoeup
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.34 no.2
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    • pp.137-142
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    • 2008
  • Echinacea purpurea, an indian traditional plant medicine has been widely used as herbal remedy for the treatment of disease such as colds or other infections. However, Echinacea purpurea extracts recently have been applied as a cosmetic ingredient for skin care. We artificially cultured Echinacea purpurea by using the bioreactor culture system for this study. We induced callus from Echinacea purpurea and separated adventitious roots, harvested and extracted after cultured in bioreactors. Previously, several studies have been reported on anti-oxidant and immuno-enhancing effects of Echinacea purpurea extract but other efficacies were not well known. In this study, we investigated the whitening, anti-wrinkle and anti-oxidant effects to know applicable value of tissue-cultured Echinacea purpurea adventitious roots extract(TCEPARE) as a cosmetic ingredient. TCEPARE did not show cytotoxicity until a concentration of 2% and showed the anti-oxidative effect in DPPH and NBT tests. Also, the extract decreased tyrosinase expression in a dose-dependent manner and inhibited melanin synthesis in B16 melanoma cells. TCEPARE reduced protein levels of MMP-1, 2 secreted in culture medium or in cell lysates. From these results we suggest that TCEPARE has potential benefits applicable as to cosmetic ingredient for skin care products.

Effects of Gamma Irradiation on the Survival and Development of the Multicolored Asian Ladybird Beetle, Harmonia axyridis (Coccinellidae; Coleoptera) (감마선이 무당벌레의 생존과 발육에 미치는 영향)

  • Seo, Mi-Ja;Lee, Hee-Jin;Kang, Eun-Jin;Kang, Si-Yong;Yu, Yong-Man;Youn, Young-Nam
    • Korean journal of applied entomology
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    • v.50 no.4
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    • pp.335-342
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    • 2011
  • The effects of gamma irradiation on the survival, development, fecundity, and sex ratio of the multicolored Asian ladybird beetle (Harmonia axyridis) were investigated. A dose of more than 50 Gy dose of irradiation on eggs completely inhibited hatch, and 1st and 3rd instar larva irradiated with over 40 Gy almost died. Adverse effects of gamma irradiation over 70 Gy were also observed in the survival and development of pupae and adults. Although irradiated individuals usually survived, they had longer periods of larval and pupal development than untreated individuals. Slight female-biased sex ratios were observed in some treatments. However, sex ratio differences soon equilibrated. Generally, inherited harmful effects of gamma irradiation were observed in F1 and F2 generations. Comet tail indicating DNA damage was showed in survival individuals exposed to gamma irradiation.

Color decomposition method for multi-primary display using 3D-LUT in linearized LAB space (멀티프라이머리 디스플레이를 위한 3D-LUT 색 신호 분리 방법)

  • Kang Dong-Woo;Cho Yang-Ho;Kim Yun-Tae;Choe Won-Hee;Ha Yeong-Ho
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.42 no.6
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    • pp.9-18
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    • 2005
  • This paper proposes the color decomposition method for multi-primary display (MPD) using a 3-dimensional look-up-table (3D-LUT) in a linearized LAB space. The proposed method decomposes conventional three-primary colors into the multi-primary control values of a display device under constraints of tristimulus match. To reproduce images on the MPD, the color signals should be estimated from a device-independent color space, such as CIEXYZ and CIELAB. In this paper, the linearized LAB space is used due to its linearity and additivity in color conversion. The proposed method constructs the 3-D LUT, which contain gamut boundary information to calculate color signals of the MPD. For the image reproduction, standard RGB or CIEXYZ is transformed to the linearized LAB and then hue and chroma are computed to refer to the 3D-LUT. In the linearlized LAB space, the color signals of a gamut boundary point with the same lightness and hue of an input point are calculated. Also, color signals of a point on gray axis are calculated with the same lightness of an input. With gamut boundary points and input point, color signals of the input points are obtained with the chroma ratio divided by the chroma of the gamut boundary point. Specially, for the hue change, neighboring boundary points are employed. As a result the proposed method guarantees the continuity of color signals and computational efficiency, and requires less amount of memory.

Development of Advanced TB Case Classification Model Using NHI Claims Data (국민건강보험 청구자료 기반의 결핵환자 분류 고도화 모형 개발)

  • Park, Il-Su;Kim, Yoo-Mi;Choi, Youn-Hee;Kim, Sung-Soo;Kim, Eun-Ju;Won, Si-Yeon;Kang, Sung-Hong
    • Journal of Digital Convergence
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    • v.11 no.9
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    • pp.289-299
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    • 2013
  • The aim of this study was to enhance the NHI claims data-based tuberculosis classification rule of KCDC(Korea centers for disease control & prevention) for an effective TB surveillance system. 8,118 cases, 10% samples of 81,199 TB cases from NHI claims data during 2009, were subject to the Medical Record Survey about whether they are real TB patients. The final study population was 7,132 cases whose medical records were surveyed. The decision tree model was evaluated as the most superior TB patients detection model. This model required the main independent variables of age, the number of anti-tuberculosis drugs, types of medical institution, tuberculosis tests, prescription days, types of TB. This model had sensitivity of 90.6%, PPV of 96.1%, and correct classification rate of 93.8%, which was better than KCDC's TB detection model with two or more NHI claims for TB and TB drugs(sensitivity of 82.6%, PPV of 95%, and correct classification rate of 80%).

A Key Management Scheme for Ad hoc Sensor Networks (애드 혹 센서 네트워크를 위한 키 관리 방안)

  • Kim Seung-Hae;Chung Byung-Ho;Wang Gi-Cheol;Cho Gi-Hwan
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.43 no.7 s.349
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    • pp.32-40
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    • 2006
  • It is very important to establish a pairwise key securely in wireless sensor networks. Because sensor networks consist of devices with weak physical security, they are likely to be compromised by an attacker. However, some approaches using key pre-distribution and other approaches using one hop local keys are known to be very vulnerable to threats caused by compromised nodes, even a small number. This paper proposes a scheme where each node establishes three hop local keys and employs them for a later pairwise key establishment. When any two nodes agree a pairwise key, all nodes on the route between two nodes contribute to the agreement of the pairwise key. Here, the initial three hop local keys are employed for encrypting a secret key delivered from a node to other nodes. Therefore, the proposed scheme bothers attackers to compromise much more nodes than the scheme using one hop local keys only. The simulation results have proven that the proposed scheme provides better performance and higher security than the scheme using one hop local keys in terms of message exchange, the number of encryption and decryption, and pairwise key exposure rate.

Study on the Direction of Korea's National Defense Strategy Focused on the Hegemony Strategy of U.S.A. (미국의 패권전략과 한국 군사전략 발전방향)

  • Kim, Sung-Woo
    • Journal of National Security and Military Science
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    • s.8
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    • pp.239-270
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    • 2010
  • This thesis is to make an appropriate national defense policy of Republic of Korea through studying the Hegemony Strategy of United States. I searched the theory of hegemony. The hegemony was differently defined by the point of time and region. The strong power nations with the hegemony have been making efforts to maintain their hegemony everytime. I have conclusion that the presence of hegemony once emerged, it brought regional stability in place whether it is coercive or beneficial. The stability and instability of international order IS not exclusively dependent on hegemony. Even if the safety of hegemony cannot guarantee absolute stability of international order, there IS on doubt that the hegemony has enormous impact on that. According to the hegemonic theory, the history of mankind equals to the history of rising and falling hegemony. The international order was changed as the hegemony changes. The United States has been making efforts to maintain her global hegemony during the post cold-war era as well. Taking all these into consideration, relevant military strategy direction able to pursue national interest is that to make up for the relative weakness in the strategic environment. South Korea have to prepare security policy response as following. First, South Korea should build the military force equipped with advanced weapons in military technology sector and solidify military diplomatic relation able to form cooperative relation in wartime. Second, South Korea should make solid Alliance of Korea and U.S. Third, develop and maintain multilateral security cooperation of East Asia. Forth, we could realize that there are means that can neutralize opponent's strong point by seeking one or two and more asymmetry in the aspect of strategy, tactics, and means through asymmetric strategy. Than the military force of South Korea should develop into a force that is able to overcome to the traditional North Korea's threat and new type of conflicts. And the force should have sufficient strength and be deployed to effectively defend the Korean Peninsula. So, we need to establish a denial and defense system against any hostile neighboring country. Therefore, ROK military forces preparing for the future should try to construct a future military power to gradually establish enough strength for self-defense to prepare for a uncertain security environment and when the Korean Peninsula is unified in a future.

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Estimation of Road Capacity at Two-Lane Freeway Work Zones Considering the Rate of Heavy Vehicles (중차량 비에 따른 편도 2차로 고속도로 공사구간 도로 용량 추정)

  • Ko, Eunjeong;Kim, Hyungjoo;Park, Shin Hyoung;Jang, Kitae
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.19 no.2
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    • pp.48-61
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    • 2020
  • The objective of this study is to estimate traffic capacity based on the heavy-vehicle ratio in a two-lane freeway work zone where one lane is blocked by construction. For this, closed circuit television (CCTV) video data of the freeway work zone was collected, and the congestion at an upstream point was observed. The traffic volume at a downstream point was analyzed after a bottleneck was created by the blockage due to the upstream congestion. A distribution model was estimated using observed-time headway, and the road capacity was analyzed using a goodness-of-fit test. Through this process, the general capacity and an equation for capacity based on the heavy-vehicle ratio passing through the work zone were presented. Capacity was estimated to be 1,181~1,422 passenger cars per hour per lane (pcphpl) at Yeongdong, and 1,475~1,589pcphpl at Jungbu Naeryuk. As the ratio of heavy vehicles increased, capacity gradually decreased. These findings can contribute to the proper capacity estimation and efficient traffic operation and management for two-lane freeway work zones that block one lane due to a work zone.

Partial denture metal framework may harbor potentially pathogenic bacteria

  • Mengatto, Cristiane Machado;Marchini, Leonardo;de Souza Bernardes, Luciano Angelo;Gomes, Sabrina Carvalho;Silva, Alecsandro Moura;Rizzatti-Barbosa, Celia Marisa
    • The Journal of Advanced Prosthodontics
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    • v.7 no.6
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    • pp.468-474
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    • 2015
  • PURPOSE. The aim of this study was to characterize and compare bacterial diversity on the removable partial denture (RPD) framework over time. MATERIALS AND METHODS. This descriptive pilot study included five women who were rehabilitated with free-end mandibular RPD. The biofilm on T-bar clasps were collected 1 week ($t_1$) and 4 months ($t_2$) after the RPD was inserted ($t_0$). Bacterial 16S rDNA was extracted and PCR amplified. Amplicons were cloned; clones were submitted to cycle sequencing, and sequences were compared with GenBank (98% similarity). RESULTS. A total of 180 sequences with more than 499 bp were obtained. Two phylogenetic trees with 84 ($t_1$) and 96 ($t_2$) clones represented the bacteria biofilm at the RPD. About 93% of the obtained phylotypes fell into 25 known species for $t_1$ and 17 for $t_2$, which were grouped in 5 phyla: Firmicutes ($t_1=82%$; $t_2=60%$), Actinobacteria ($t_1=5%$; $t_2=10%$), Bacteroidetes ($t_1=2%$; $t_2=6%$), Proteobacteria ($t_1=10%$; $t_2=15%$) and Fusobacteria ($t_1=1%$; $t_2=8%$). The libraries also include 3 novel phylotypes for $t_1$ and 11 for $t_2$. Library $t_2$ differs from $t_1$ (P=.004); $t_1$ is a subset of the $t_2$ (P=.052). Periodontal pathogens, such as F. nucleatum, were more prevalent in $t_2$. CONCLUSION. The biofilm composition of the RPD metal clasps changed along time after RPD wearing. The RPD framework may act as a reservoir for potentially pathogenic bacteria and the RPD wearers may benefit from regular follow-up visits and strategies on prosthesis-related oral health instructions.

Planning of Optimal Work Path for Minimizing Exposure Dose During Radiation Work in Radwaste Storage (방사성 폐기물 저장시설에서의 방사선 작업 중 피폭선량 최소화를 위한 최적 작업경로 계획)

  • Park, Won-Man;Kim, Kyung-Soo;Whang, Joo-Ho
    • Journal of Radiation Protection and Research
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    • v.30 no.1
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    • pp.17-25
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    • 2005
  • Since the safety of nuclear power plant has been becoming a big social issue the exposure dose of radiation for workers has been one of the important factors concerning the safety problem. The existing calculation methods of radiation dose used in the planning of radiation work assume that dose rate does not depend on the location within a work space thus the variation of exposure dose by different work path is not considered. In this study, a modified numerical method was presented to estimate the exposure dose during radiation work in radwaste storage considering the effects of the distance between a worker and sources. And a new numerical algorithm was suggested to search the optimal work path minimizing the exposure dose in pre-defined work space with given radiation sources. Finally, a virtual work simulation program was developed to visualize the exposure dose of radiation doting radiation works in radwaste storage and provide the capability of simulation for work planning. As a numerical example, a test radiation work was simulated under given space and two radiation sources, and the suggested optimal work path was compared with three predefined work paths. The optimal work path obtained in the study could reduce the exposure dose for the given test work. Based on the results, tile developed numerical method and simulation program could be useful tools in the planning of radiation work.

An Experimental Study on the Direct Contamination Pathway of Elemental iodine Vapor $(I_2)$ for Rice Plants (벼에 대한 원소상 요오드 증기$(I_2)$의 직접오염경로 해석 실험)

  • Choi, Y.H.;Lim, K.M.;Lee, C.M.;Park, H.G.;Park, D.W.;Choi, G.S.;Choi, H.J.;Lee, H.S.;Lee, C.W.
    • Journal of Radiation Protection and Research
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    • v.29 no.3
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    • pp.165-172
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    • 2004
  • Rice plants were exposed to $I_2$ vapor for 80 min at different growth stages in an exposure box to investigate the parameters concerning direct plant contamination. Deposition velocity $(m\;s^{-1})$ of the $I_2$ vapor for the straws was in the range of $1.4{\times}10^{-5}-1.3{\times}10^{-4}$ depending on the exposure time, being comparatively low during the earlier part of the plant growth. Ear deposition velocity was in the range of $2.5{\times}10^{-5}-6.7{\times}10^{-5}$. Whole-plant deposition velocity was in the range of $1.4{\times}10^{-5}-1.8{\times}10^{-4}$ with the highest from the exposure performed on Aug. 18 (7 d after the start of heading). The time-dependent variation generally decreased when the deposition velocity was normalized to the biomass density No noteworthy tendency in the deposition velocity was observed with regard to the temperature, sunlight and humidity. Translocation factor for the hulled seeds was $3.3{\times}10^{-5}-4.7{\times}10^{-4}$ with the highest from the Aug. 23 exposure. It was found that a leaf deposition even before the ear emergence resulted in a considerable seed translocation.