• 대한한방부인과학회지
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• 제21권3호
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• pp.1-17
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• 2008

Purpose: Scutellaria baicalensis is a herb which has effect of eliminating heat, drying dampness, purging away fire, detoxicating. Clinically, has been used to remove fever and control of inflammation. We have studied in series to investigate the effective traditional oriental medicines of treatment for endometriosis. In this study, the effects of Scutellaria baicalensis administrated orally or rectally on surgically induced endometriosis in rat were investigated. Methods: The endometrial tissues of rats were autografted to their small intestine. Rats with surgically induced endometriosis were administered with Scutellaria baicalensis extracts for 40 days orally or rectally. We observed the tissue size of ectopic uterine implants at the mesenteric with the naked eye and examined the concentration of estradiol, progesterone, $TNF-{\alpha}$ and IL-2, IL-4, IL-6 and IL-10 in serum. Also, we inquired which was more effective between oral administration groups and rectal administration groups. Results: The size of ectopic uterine implants of orally or rectally treated groups was much smaller than those of control groups. The concentrations of estradiol, progesterone, $TNF-{\alpha}$, IL-2 and IL-6 were significantly decreased in oral administration experimental group compared with the control group. The concentrations of progesteron, $TNF-{\alpha}$, IL-2 and IL-6 were significantly decreased in rectal administration experimental group compared with the control group. The efficiency of oral administration group was better than that of rectal administration group at the serum concentration of estradiol and IL-4. Conclusion: Our data suggest that Scutellaria baicalensis inhibit the inflammation induced from ectopic uterine implants at the mesenteric wall and inhibit the growth of ectopic uterine implants. Judging from the above results, it can be suggested that Scutellaria. baicalensis should be a useful agent for inhibiting the inflammation induced from ectopic uterine implants and the proliferation of endometriosis. Maybe, oral administration of Scutellaria baicalensis is more effective than rectal administration.

• Journal of Microbiology and Biotechnology
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• 제29권5호
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• pp.687-695
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• 2019

In a previous work, we performed de novo RNA sequencing of Allomyrina dichotoma using next generation sequencing and identified several antimicrobial peptide candidates based on transcriptome analysis. Among them, a cationic antimicrobial peptide, allomyrinasin, was selected bioinformatically based on its physicochemical properties. Here, we assessed the antimicrobial and anti-inflammatory activities of allomyrinasin against microorganisms and mouse macrophage Raw264.7 cells. Allomyrinasin showed antimicrobial activities against various microbes and decreased the nitric oxide production of the lipopolysaccharide-induced Raw264.7 cells. Furthermore, quantitative RT-PCR and ELISA revealed that allomyrinasin reduced cytokine expression levels in the Raw264.7 cells. We also identified inducible nitric oxide synthase, cyclooxygenase-2 expression, and $PGE_2$ production through western blot analysis and ELISA. We confirmed that allomyrinasin bound to bacterial cell membranes via a specific interaction with lipopolysaccharides. Taken together, these data indicate that allomyrinasin has antimicrobial and anti-inflammatory activities as exemplified in lipopolysaccharide-induced Raw264.7 cells. We have provided a potentially useful antimicrobial peptide candidate that has both antimicrobial and anti-inflammatory activities.

• 한국작물학회지
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• 제64권3호
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• pp.213-224
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• 2019

There is an increasing frequency in the occurrence of abnormal weather phenomena such as sharp increases and decreases in temperature. Under these weather conditions, the heading time of rice changes unexpectedly, which poses problems in agriculture. Therefore, we investigated the effect of temperature on the heading response at different growth stages in rice. During the period from transplanting to heading, the plants were subjected to different temperature treatments, each for a 9-day period, to observe the heading response. For the heading date analysis, "heading date" was defined as the number of days from transplanting to the appearance of the first spikelet. We found that the influence of temperature increased in the order of rooting stage, followed by meiosis, early tillering, spikelet differentiation, and panicle initiation stage in all ecological types and cultivars. In particular, unlike the results reported previously, the effect of temperature on heading during the photo-sensitive period was very small. Meanwhile, the influence of temperature on vegetative growth response at different growth stages was not consistent with heading response. These results can be used as basic data for predicting the variation in heading date owing to temperature variation at each growth stage. In addition, we propose that the concept of day length should be included in determining the influence of temperature on the photo-sensitive period.

• 유통과학연구
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• 제12권7호
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• pp.23-35
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• 2014

Purpose - This study aims to explore the effects of social responsibility activities and business ethics practices on corporate trust and loyalty in the context of a large retail distribution business. Research design, data, and methodology - The data collected was analyzed using PASW Statistics 18.0. In order to verify the demographic characteristics, frequency analysis was conducted on the data. Results - The results of the study were as follows. First, social responsibility activities had a significant effect on corporate trust. Second, both corporate social responsibility activities and business ethics practices had significant effects on loyalty. Third, corporate trust had a significant effect on loyalty. Fourth, corporate social responsibility activities and consumer protection activities had a partial mediation effect, while environmental protection activities and social contribution activities had complete mediation effects. Conclusions - This study clarified and explained the factors of corporate social responsibility activities and business ethics practices that customers value, and analyzed the influence of these factors on corporate trust and loyalty.

• 한국경영정보학회:학술대회논문집
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• 한국경영정보학회 2008년도 춘계학술대회
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• pp.428-433
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• 2008

The online advertising industry's business model undertakes the change from CPM (cost-per-mille)-based to CPC (cost-per-click)-based. However, due to the problem of 'Click Fraud', CPA (cost-per-action) has been regarded as a new step. For CPA, publishers need to get information after a user clicks an advertisement. Therefore, in CPA, the key is to get Conversion Action Data (CAD). This paper introduces two existing mechanisms for getting CAD, compare their characteristics, and analyze their limitations. Then the two new mechanisms are introduced and their requirements and feasibility are analyzed. Lastly, we compare the existing two and the new two mechanisms, and point out each mechanism's business possibility, value and Application Area. This paper will help publishers choose the most appropriate mechanism on the basis of their situation.

• 보건의료산업학회지
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• 제7권3호
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• pp.225-235
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• 2013

This study purposed to analyze the productivity of regional medical capacity in attracting medical tourist between 2009 and 2011. Data envelopment analysis (DEA) and Malmquist productivity index (MPI) were applied to test the productivity and changes in study periods. The DEA model included a number of doctors, nurses, and beds as input factors, and a number of inpatient and outpatient, and hospital income as output factors. The result of the study were as follow. Jeju had efficiency value of 1 for three years. Seoul, Busan, Daegu, Daejeon, Ulsan, Gyeonggi, Gangwon, Jeonnam, Gyeongbuk, and Gyeongnam showed an increasing trend of efficiency value over three years. Seoul had the efficiency value, 1, in 2011. But, Incheon, Gwangju showed decreasing efficiency score during the study period. MPI showed overall productivity decrease during the period. Further studies will be needed by collecting more time-series data.

• 수산경영론집
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• 제42권1호
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• pp.85-96
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• 2011

We have done the input-output analysis to see the over all impact of flounder industry of Jeju region on the domestic economy of Korea. To do the input-output analysis, we have constructed the data set for the input-output table by using the existing data set in the "2003 input- output table of Jeju regional area" published by the joint work of Jeju branch of Korea bank and the Jeju Development Institute, together with some raw data provided by Jejudo Marine Fish-Culture Cooperative. We have also produced input coefficient of flounder industry by making flounder industrial sector exogenous, separated from intermediate demand. To summarize our empirical results, the inducement effect of production, value added, and employment of Jeju flounder aquaculture industry are 300 billion won, 116 billion won and 1,800 people respectively. In conclusion, the results of this study suggest flounder industry of Jeju region contributes powerfully to not only Jeju economy but also all over the Korea economy.

• Asian Journal of Business Environment
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• 제4권3호
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• pp.13-18
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• 2014

Purpose - This study examines students' perspectives (stream-wise) of parameters affecting education quality in an affiliated undergraduate engineering institution in NCR, Haryana. Research design, data, and methodology - This study involves descriptive research and data collection using a structured questionnaire based on the Likert scale. The sample comprises 500 student respondents. For data analysis, an f-test was performed using high quality SPSS software. Results - For "Selection" and "Personality Development & Industry Exposure," the analysis of variance revealed a statistical difference between the mean values of the groups. Whereas, for "Academic Excellence," "Infrastructure," "Placements," and "Management & Administration," the analysis of variance revealed no statistical difference between the mean values of the groups. Conclusions - Students' perceptions about the "Selection" and "Personality Development & Industry Exposure" change according to the various specializations they opt for in their undergraduate engineering education in Haryana. Whereas, for "Academic Excellence," "Infrastructure," "Placements," and "Management & Administration," the perceptions of the students do not vary because of the different specializations they have opted for in their undergraduate engineering education.

• 품질경영학회지
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• 제36권1호
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• pp.80-88
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• 2008

The 21st century is often called the knowledge-based information society. A new term, Data Technology (DT), which handles data and creation of information, is defined. A few important concepts of DT which are related to Six Sigma are described. Also some characteristics of Knowledge Management (KM) which provide new knowledge are explained. As a new direction of Six Sigma, Six Sigma Focused on Knowledge Creation (SSFKC) is suggested. The way of implementation of SSFKC and its relationship with DT and KM are elaborated.

• 간호행정학회지
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• 제18권1호
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• pp.87-95
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• 2012

Purpose: This study was conducted to explore the perspectives of gender and role in the family for nurses' work-family balance. Method: Data were collected through in-depth interviews with 14 married nurses having children, who were selected through convenience sampling and purposive sampling from November 1, 2011 to January 20, 2012. The data were analyzed using qualitative thematic analysis. Results: The common themes resulted from data analysis included following traditional gender roles, giving up any expectation of spouse's role, coordinating the division of family roles, and refusing to stick to gender roles. The age of nurse, family background of husband, and social-economic contexts were essential to explain the couple dynamics. Conclusions: Nurses who received private family support were stably leading a work-family balance, yet unable to change the gender structure of spouse for the work-family balance. On the other hand, young nurses who were unable to get any support, had a tendency of cooperating with their spouses and adopting more negotiable and pragmatic approach to work-family balance.