• 대한기관식도과학회지
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• 제5권2호
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• pp.174-181
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• 1999

The palatine tonsils(tonsils) and pharyngeal tonsils(adenoids) are situated at the entrance of the respiratory and alimentary tracts and represent the first site of contact with a variety of microorganisms and other antigens present in food and inhaled air. They are known as lymphoid organs carrying out the function of cellular and humoral immunity, and so they form a local protective barrier. And the expression of the vascular endothelial adhesion molecules is known to play an important role for the inflammatory reaction in tonsils and adenoids as well as in other inflammatory tissues, by binding with the receptors on the surface of leukocytes. But although several scientific hypotheses on the role of these lympoid tissues have been suggested, their complete functions have remained unknown. The purpose of this study is to present an basic data of the knowledge on the immunologic physiology of the tonsils and adenoids and their role as active immunologic organs that reinforce the mucosal immunity of the entire upper aerodigestive tract. We examined 16 human tonsils and adenoids and the expression of three endothelial adhesion molecules, vascular endothelial adhesion molecule-1(VCAM-1), intracellular adhesion molecule-1(ICAM-1), and E-selection, in tissue sections using immunohistochemistry. We used the inferior turbinate mucosa obtained from 9 patients getting septal surgery as a control group. The expressions of vascular endothelial adhesion molecule-1(VCAM-1) and intracellular adhesion molecule-1 (ICAM-1) were significantly higher in the tonsils and adenoids. But respectively, there were no significant differences between the tonsils and adenoids. The expression of E-selection was significant higher in the tonsils, but not in the adenoids. We observed that tonsils and adenoids showed significantly higher expressions of vascular endothelial adhesion molecule-1(VCAM-1), intracellular adhesion molecule-1(ICAM-1), and E-selection (in the case of E-selection, only in the tonsils). We propose that these adhesion molecules play an important role for the immunologic reaction by the transendothelial migration of lymphocytes and binding with the receptors on the surface of leukocytes.

• Journal of Yeungnam Medical Science
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• 제5권2호
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• pp.71-77
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• 1988

Adenoids 비인두폐쇄로 인해 구호흡이 유발된 6~12세의 아동 50명과 동일 연령분포의 정상아동 50명의 두부방사선 계측사진을 통해 Tongue, Mandible 및 Hyoid bone에 대한 수평, 수직 및 각도 계측에 대한 비교 연구 결과 다음과 같은 결론을 얻었다. 1. Tongue position은 실험 군에서 더 전하방 위치하는 것으로 관철되었다. 2. Mandibular position은 실험군에서 더 하방위치 하는 것으로 관찰되었다. 3. Hyoid bone의 위치는 실험군에서 더 전하방위치하는 것으로 관찰되었다.

• 치과방사선
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• 제21권1호
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• pp.45-63
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• 1991

This comparative study was designed to ascertain whether any differences existed between skeletal class Ⅱ malocclusion (

• 대한치과교정학회지
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• 제30권6호
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• pp.699-712
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• 2000

림프조직은 비인두 부위에서 Waldeyer's ring의 일부조직으로 tonsil을 이루며 정상적으로 존재한다. 이러한 림프조직이 임상적인 증상을 나타낼 정도로 과증식한 것을 'Adenoid vegetation or Adenoids'라고 이른다. 아데노이드는 일반적으로 유년기에 발생하며 $2\~12$세때 특징적인 증상을 보인다. 사춘기시기에 이르면 절대적인 아데노이드 크기 감소와 주변의 비인두의 성장으로 인한 상대적 크기 감소가 나타난다. 그리하여 성인이 되면 아데노이드는 퇴화된 상태로 변하게 된다. 아데노이드는 구호흡의 주요한 원인 중 하나이며, '아데노이드 얼굴'이라는 특징적인 안면형태를 야기한다고 알려져 있다. 아데노이드에 의한 구호흡이 안면 형태와 치열에 영향을 미칠 수 있다는 주장은 오래 전부터 제기되고 있으나, 여러 가지 복합적인 원인으로 이들간의 상호연관정도를 정확히 알기가 어려웠다. 이에 본 연구에서는 정상 교합 아동에서의 골 연령에 따라 아데노이드와 악골 크기의 정상치와 성장변화량을 제시하고 이들간의 상관관계를 알아보았으며 다음과 같은 결과를 얻었다. 1. 골 연령에 따른 남녀별 계측항목의 평균과 표준편차를 얻었다. 2. 같은 골연령을 비교시 남자는 여자보다 약 2년 가량 성장속도가 느렸다. 3. 비인두의 height과 depth는 남자에서는 CVMI 1과 2 때 많은 성장을 보이고, CVMI 4 이후에서는 성장을 보이지 않았으며, 여자에서는 모든 골 연령에서 유사한 정도의 성장이 나타났다. 4. 비인두의 상대적 면적은 남자에서 CVMI 1에서 2로 이행되는 시기에 유의한 증가를 보였다. 5. 비기도의 상대적 면적과의 상관분석에서 남녀 모두에서 아데노이드 항목중에서는 Ad2와 관련된 항목과 uppe pharynx가 높은 상관관계를 보였으며, 치열궁과 관련된 항목중에는 상$\cdot$하악의 견치간 너비, 상악의 대구치간 너비, 구개정 높이가 상관관계가 있었다.

• 치과방사선
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• 제12권1호
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• pp.81-103
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• 1982

The aim of this study was to investigate the variation in shape, size and area of the pharynx and adenoids, and to analyze the relationship between pharyngeal cavity and upper facial cranium which effected on morphology of those parts in Korean. Age changes and sex differences in those areas were comprised in this study. Materials included 272 lateral cephalograms, which were divided into 4 groups by age; (1) 7-year-old group consisted of 29 males and 30 females, (2) 12-year-old group consisted of 30 males and 30 females, (3) 17-year-old group consisted of 30 males and 40 females, (4) 20-year-old group consisted of 37 males and 46 females. In subjects each variable was measured and evaluated statistically introducing 17 reference points and 17 reference lines respectively. Conclusions from this study were as follows. 1. Linear measurements of the bony nasopharynx revealed that the depth and height were larger in male than those in female in 17 and 20-year-old groups. 2. Linear measurements of the upper facial cranium were larger in male than those in female in all age groups. 3. Angular measurements of the bony nasopharynx and upper facial cranium did not show, on an average, sex differences in each age group. 4. As regards area of the bony nasopharynx, it increased gradually with age in both sexes. And the area was greater in male than that in female in 17 and 20-year old groups. 5. There were sex differences in area of the adenoids of which the area was larger in male than that in female in 17 and 20-year-old groups. And the area reached a peak at 17-year-old group in male and at 12 year-old group in female. 6. Area of the pharyngeal cavity increased gradually with age in both sexes, but no sex differences were noted in each age group. 7. Rate of area of the adenoids to that of the pharyngeal cavity decreased continually with age, and no sex differences were noted in all age groups. 8. In amounts and its differences of the growth, there were sex differences in the posterior upper facial height, and were not in area of the bony nasopharynx, pharyngeal cavity and adenoids in each age group.

• 대한치과교정학회지
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• 제26권6호
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• pp.647-655
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• 1996

In discussing the effects of adenoids on the development of the face and dentition, it is important to note their influence on the mode of breathing and to relate this to specific facial types and dentition. This study, therefore, assumed that the ability to adapt to individual's neuromuscular complex is various. And tried to investigate the effects of reduced nasal respiratory function on the development of dentition by facial type. This paper is based on children patients with enlarged adenoids and comparing them to data taken from a control group with normal respiratory function. Among the three facial types, the most statistical significant difference was observed from dolichofacial type between experimental and control group. In dolichofacial type, the experimental group showed labioversion of upper incisor, decrease in the width of upper arch, increase in overjet, increase in the rate of cross-bite, and increase in the height of palatal vault. No significant difference was observed between the two groups in the inclination of upper and lower incisors in mesofacial type, but the experimental group was observed to show decrease in the width of upper arch and increase in the height of palatal vault. On the other hand, in brachyfacial type, no significant difference was observed between the two groups in dentition variables except showing linguoversion of upper incisor. The results, which were observed in dolichofacial type, consist with Nordlund's theory of Compression.

• Journal of Yeungnam Medical Science
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• 제10권1호
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• pp.37-47
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• 1993

인두편도 증식으로 인한 비호흡 장애가 치열 및 핵의 위치에 미치는 영향을 안모형태에 따라 비교 연구하기 위해 인두편도 증식으로 인두편도 절제술을 시행하기로 한 환자의 안모를 형태에 따라 mesofacial, brachyfacial, dolichofacial type으로 분류하여 각 type별로 20명의 환자를 설정하여 서로 비교 연구한 결과 1. 상악 구치부 치열궁 폭경에 있어서 안모 형태에 따른 유의한 차이를 보였으며, dolichofacial type의 안모를 가진 환자에서 가장 좁은 상악 구치부 치열궁 폭경을 보였다. 2. 혀의 수직적 위치에 있어서 안모형태에 따른 유의한 차이를 보였으며, dolichofacial type의 안모를 가진 환자에서 혀가 가장 하방에 위치함을 보였다.

• 대한치과의사협회지
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• 제40권8호통권399호
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• pp.620-627
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• 2002

Oral health depends on the intergrity of the oral mucosa for prevention of the penetration of microbes and macromolecules that might be infectious, allergenic or antigenic. The intraoral immune systems include the tonsils, adenoids and nasopharyngeal-associated lymphoreticular tissue, or NALT. Mucosal inductive sites of the gastrointestinal tract(Peyer's patches and the appendix) and solitary lymph nodes collectively compose the gut-associated lymphoreticualr tissue, or GALT system. Both NALT and GALT are inductive regions where foreign antigens derived from viruses, bacteria, yeast and other molecules are encountered. The integration of tissues in NALT and GALT as part of the mucosal immune system, is very important to keep the oral immune system.

• 대한유전성대사질환학회지
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• 제14권2호
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• pp.156-162
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• 2014

A 25-month-old boy was referred to the hospital due to large head detected on routine physical examination. At visit, dysmorphic facial appearances, including broad nose, prominent forehead, and coarse face, were noted. Nasal obstruction with nasal voice, prominent adenoids, and bilateral middle ear effusions were detected. His abdomen was distended, and liver and spleen were palpated about 3 finger and 2 finger breadths, respectively. He was operated for bilateral inguinal hernias. The motion of both elbow joints was mildly limited on supination and pronation. Urinary level of glycosaminoglycan was elevated and the enzyme activity of iduronate sulfatase in leukocytes was decreased. The mutational analysis of the gene iduronate 2-sulfatase (IDS) revealed c.263G>A (p.Arg88His) mutation. His developmental scale showed delayed development and there was cardiac valvular involvement (tricuspid regurgitation and mitral valve prolapse). After the diagnosis of Hunter syndrome, enzyme replacement therapy started on a weekly basis without progression of any clinical features. Here we report a case of early diagnosed Hunter syndrome detected by large head on routine examination. Thus, it is important to associate Hunter syndrome in the patient with large head especially, if there is the history of bilateral inguinal hernia and prominent adenoids to increase the possibility of early diagnosis and treatment.

• 수면정신생리
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• 제12권2호
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• pp.98-104
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• 2005

Approximately 1% to 3% of all children have obstructive sleep apnea syndrome (OSAS). OSAS in children can lead to a variety of symptoms and sequalae; impairment of development and quality of life, behavioral and personality disturbance, learning problem, cor pulmonale and hypertension. Diagnosis and treatment of OASA for children are different from those for adults in many respects. Adenotonsillar hypertrophy is major cause of childhood OSAS. Overnight polysomnography in a sleep laboratory is the gold standard for diagnosing childhood OSAS. However, because full polysomnography in children may be difficult to obtain, expensive, and inconvenient, other methods to diagnose OSAS have been investigated. Adenotonsillectomy is the most common surgical treatment of childhood OSAS. But if residual symptoms remained after adenotonsillectomy, it should be considered to additional treatment such as weight control, sleep positional change, and continuous positive airway pressure (CPAP).