• Journal of Periodontal and Implant Science
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• 제32권1호
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• pp.249-255
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• 2002

Zea Mays L. has been known to be effective for improving tissue health and Magnoliae cortex to have effective antibacterial and antimicrobial activity against pathogenic microbes. The purpose of this study was to examine the antimicrobial effects of Zea Mays L. and Magnoliae cortex extract mixtures on periodontal pathogens(Prevotella intermedia, Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Streptococcus mutans )and to examine the effects on human gingival fibroblast cellular activity. Zea Mays L. and Magnoliae cortex extracts and their mixtures were prepared with various mixing ratios (0.5:1, 1:1, 1.5:1, 2:1). These extracts were loaded to periodontal pathogen cultured petri dish for antimicrobial test and also loaded to cultured human gingival fibroblast for cellular activity test. Each test was repeated 3 times and data were analyzed by one-way ANOVA with 95% confidence level. Mixture of these two extracts showed greater amount of inhibition area on periodontal pathogen and more improved gingival fibroblast activity as Zea Mays L. ratio reduced. So, mixture ratio 0.5:1 (Zea Mays L. : Magnoliae cortex) group showed statistical significance in antimicrobial activity and cellular activity among various mixtures(p < 0.05). In conclusion, 0.5:1 (Zea Mays L. : Magnoliae cortex) mixture possessed best gingival fibroblast cellular activity and antimicrobial activity toward periodontal pathogens.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제34권4호
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• pp.242-249
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• 2023

Objectives: Following the coronavirus disease 2019 (COVID-19) pandemic, adolescents have experienced decreased physical activity and a decline in mental health. This study analyzed the association between changes in depressed mood after the COVID-19 pandemic and physical activity among adolescents. Methods: The analysis was based on the results of the 17th Youth Health Behavior Online Survey conducted in 2021, which included 54848 middle and high school students in South Korea. Information on physical activity included low-intensity physical activity lasting >60 min/day, high-intensity physical activity, and strength training exercises. A logistic regression analysis was performed to evaluate the association between physical activity and changes in depression after the COVID-19 pandemic. Results: After adjusting for sociodemographic characteristics and previous depression, adolescents who performed strength training exercises more than once per week had a 0.95-fold lower risk (odds ratio [OR]=0.948, 95% confidence interval [CI]=0.905-0.994, p=0.027) of increasing depression after the COVID-19 pandemic, while the risk of decreasing depression increased by 1.22-fold (OR=1.215, 95% CI=1.131-1.305, p<0.001). The results were not significant for low-intensity physical activity for >60 min/day and high-intensity physical activity. Conclusion: Strength-training exercises are significantly associated with the prevention of depression among adolescents following the COVID-19 pandemic.

• 한국대기환경학회지
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• 제30권1호
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• pp.26-36
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• 2014

The uncertainty assessment is important to improve the reliability of emission inventory data. The DARS (Data Attribute Rating System) have recommended as the uncertainty assessment technic of emission inventory by U.S. EPA (Environmental Protection Agency) EIIP (Emission Inventory Improvement Program). The DARS score is based on the perceived quality of the emission factor and activity data. Scores are assigned to four attributes; measurement/method, source specificity, spatial congruity and temporal congruity. The resulting emission factor and activity rate scores are combined to arrive at an overall confidence rating for the inventory. So DARS is believed to be a useful tool and may provide more information about inventories than the usual qualitative grading procedures (e.g. A through E). In this study, the uncertainty assessment for 2009 CAPSS (Clean Air Policy Support System) emission inventory is conducted by DARS. According to the result of this uncertainty assessment, the uncertainty for fugitive dust emission data is higher than other sources, the uncertainty of emission factor for surface coating is the highest value, and the uncertainty of activity data for motor cycle is the highest value. Also it is analysed that the improvement of uncertainty for activity data is as much important as the improvement for emission factor to upgrade the reliability of CAPSS emission inventory.

• 생약학회지
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• 제27권4호
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• pp.309-315
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• 1996

As part of our search for less toxic antimicrobial agents from natural resources, antimicrobial activity of rutin isolated from Sophora japonica was tested in vitro against four kinds of gram positive bacteria and four kinds of gram negative bacteria by serial broth dilution method. Among eight kinds of bacteria tested, the antimicrobial activity of rutin was the most potent against Mycobacterium smegmatis showing MIC of $375\;{\mu}g/ml$. The acute toxicity of rutin was examined in mice and rats. and $LD_{50}$ value administered intraperitoneally in mice was 650 mg/kg(Confidence limit: 894-1,473 mg/kg). There were no significant changes in serum biochemical values and histopathological changes as compared with those of control after intraperitoneal administration with rutin in rats.

• 한국콘텐츠학회논문지
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• 제8권7호
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• pp.103-111
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• 2008

초등학교 학생의 인지발달 단계의 특성을 고려하여 개발된 교수 학습용 소프트웨어는 별로 없다. 본 논문는 초등학교 도형 학습에 있어서 도형의 개념을 확실히 인지시키기 위해 시간적, 공간적 제약이 많은 구체물을 대신할 수 있는 조작활동 중심의 소프트웨어, 즉 컴퓨터 화면상에서 학생들이 다양하게 조작할 수 있고, 프로그램을 익히는데 부담을 느끼지 않아 쉽게 활용할 수 있도록 개발된 교수 학습용 자료가 도형 학습에 효과가 있는지를 분석하는데 목적이 있다. 이것을 통하여 효율적인 도형 학습 지도 방안과 교수 학습용 소프트웨어의 개발 방안에 대한 시사점을 찾고자 한다.

• 한국물환경학회지
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• 제18권4호
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• pp.395-400
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• 2002

Lead is one of the most toxic metal and is detectable in practically all phases of environment and in all biological system. Transport, industrial and domestic waste products are the main sources of this pollutant. Ingested lead is rapidly absorbed and widely distributed throughout the body, causing extensive tissue damage. In this study, we chose the freshwater decapods Maceobrachium nipponnese as a sensitive indicator organism for environmental pollution. In order to investigate the possibility in use of $Na^+/K^+ATPase$ activity as a biomarker of lead pollution, we tested the acute toxicity of lead to Maceobrachium nipponnese. The $LC_{50}(96hr)$ value for lead in Maceobrachium nipponnese was found to be $446{\mu}g/L$ with the 95% confidence limits. The lead exposure group at $LC_{50}$ showed a significant $Na^+/K^+ATPase$ inhibition, depending on the exposure time. Comparision of several concentrations of lead revealed that the $Na^+/K^+ATPase$ activity in Maceobrachium nipponnese was significantly decreased in a concentration dependent manner. These results suggest that $Na^+/K^+ATPase$ activity in Maceobrachium nipponnese may possibly be used as a biomarker of lead pollution in aquatic ecosystem.

• 한국학교수학회논문집
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• 제7권1호
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• pp.121-138
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• 2004

본 논문에서는 제7차 교육과정의 특색중의 하나인 교과재량활동시간의 효율적 운영에 관하여 연구하였다. 교과재량 활동시간에 '함께가자! 우리' 프로그램의 운영을 통하여 다양한 수학에 대한 경험, 실생활을 소재로 한 수학문제, 수준별 협동학습 수학에 대한 흥미를 유발시켰으며, 1:1 맞춤학습에 의한 부담 없는 질문과 학습의 분위기 조성 등이 학생들의 자기주도적 학습력을 향상시키는데 많은 도움을 주었음을 알 수 있다.

• 수산해양교육연구
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• 제16권2호
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• pp.171-180
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• 2004

The purpose of the present study is to study how the understanding of growing of child to be related with recognizing the role of parents and activity of bringing up, and at the same time verifying a part of father through reviewing difference view with mother's. Object of investigation were 396 members of parents who have babies in infancy (177 members of fathers and 219 members of mothers. ). The result of this research shows that father has stronger confidence than mother in the role of parents relatively, but he does not understand as much as mother does in growing of child, and is not active enough in bringing up, keeps less intimate relationship with his child and does not affect on his child than mother does. And father who has more understanding on growing of child has also more positive activity in bringing up child. We can get one conclusion from this research, now a days it is seriously required for a father to participate more corporately in bringing up his child, we should do support more effort to let father gets better and right understanding in growing of child and building-up more effective and positive relation with his child.

• 대한간호학회지
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• 제49권5호
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• pp.586-600
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• 2019

Purpose: This study aimed to develop a web-based cost management program for visiting nursing centers (CMP-VNC), using time-driven activity-based costing (TD-ABC), and to analyze effects of the program. Methods: The CMP-VNC was developed using the combined prototyping approach and system developing life cycle method following four stages: need analysis with comprehensive literature reviews and focus group interviews, design and development of program algorithm, evaluation of the developed program validity using experts and users group, and application and effects analysis. The non-equivalent control group pretest-posttest design was used to analyze the effects of the program. The program demonstration was conducted for four weeks with 60 visiting nurses in 35 visiting centers. Results: The web-based program was developed. It has five interfaces with basic and special functions using TD-ABC, namely, input, visiting nursing activity, visiting nursing activity cost, cost efficiency, and cost calculation report. The experimental group showed significantly higher cost perception and cost confidence than control group. Conclusion: We found that the CMP-VNC can be an effective tool to increase visiting nurses' competency of costing and enhance efficiencies of visiting nursing centers.

• 대한물리의학회지
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• 제11권2호
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• pp.115-121
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• 2016

PURPOSE: Many studies have reported the improvement of cognition through physical activity among subject with dementia. This study aimed to whether the current studies supports that physical activity intervention is efficacious on cognitive performance in subject with dementia. METHODS: Two independent reviewers searched National assembly library, RISS, KISS (2005-2015) using the concepts of dementia, exercise, and physical activity. We included randomized controlled trials that examined the efficacy of physical activity in subject with dementia. A meta-analysis was performed to estimate the effect sizes cognition with CMA (Comprehensive Meta-Analysis, version 2.2.064) soft-ware program. Nine randomized controlled trials were included, providing data from 133 individuals and excluding those failing to criteria of this study. RESULTS: The meta-analysis showed that physical activity intervention had a rather small effect sizes of 0.36 (95% confidence interval 0.14-0.59) on cognition performance in subject with dementia. Outcome measurement were MMSE-K (Mini-mental state examination Korean version) and LOCTA (Loewenstein Occupational Therapy Cognitive Assessment). We found heterogeneous among studies and there was difference between the studies (Q = 19.63, d(f)=12, $I^2= 38.88$). CONCLUSION: The present analysis suggests that physical activity interventions have the low effect sizes on cognition performance in subject with dementia Further studies will be required to develop the various programs for improving the cognitive performance in subject with dementia.