• Proceedings of the KIPE Conference
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• 2004.07a
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• pp.439-442
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• 2004

This paper described a dc power system, which can generate the excessive do power form do bus line to ac source in substation for traction system. The proposed regeneration inverter system for dc traction can be used as both an inverter and an active power filter(APF). As a regeneration inverter mode, it can recycle regenerative energy caused by decelerating tractions and as an active power filter mode, it can compensate for harmonic distortion produced by the rectifier substation.

• Animal cells and systems
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• v.16 no.6
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• pp.462-468
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• 2012

Urodeles including newt and salamander have remarkable regenerative capacity during the postembryonic life span. Some of the unique features are the formation of the well-developed wound epidermis and the active dedifferentiation process in the early phase of regeneration. These are regarded as key events for the successful regeneration since no further regenerative activity is possible without them. In this study, we investigated the role of retinoic acid (RA) in salamander limb regeneration by blocking RA synthesis using disulfiram, an inhibitor of aldehyde dehydrogenase that oxidizes retinal to RA. Disulfiram treatment resulted in delaying the limb regeneration processes via inhibition of wound epidermis formation and dedifferentiation process. When RA was administered after disulfiram treatment, the inhibitory effect of disulfiram was rescued. In addition, disulfiram treatment after the dedifferentiation stage resulted in the mild retardation of limb regeneration, suggesting that RA might also be involved in the blastema outgrowth. Furthermore, salamander MMP-9 gene expression was also inhibited by disulfiram treatment. Collectively, our findings indicate that endogenous RA may play an important role(s) in the early phase of limb regeneration by regulating the expression of molecules responsible for the modification of intracellular and extracellular environment during salamander limb regeneration.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.18 no.5
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• pp.96-104
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• 2004

This paper proposes a dc power regenerating systems, which can generate the excessive dc power from dc bus line to ac supply in substations for traction system The proposed regeneration inverter system for dc traction can be used as both an inverter and an active power filter(APF). As an regeneration inverter mode, it can recycle regenerative energy caused by decelerating tractions and as an active power filter mode, it can compensate for harmonic distortion produced by the rectifier substation. From the viewpoint of both power capacity and switching losses, the system is designed on the basis of three phase PWM inverters and composed of parallel inverters, output transformers, and an LCL filter.

• Journal of the Architectural Institute of Korea Planning & Design
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• v.36 no.2
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• pp.71-78
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• 2020

This study focused on the 'public architecture' of each local area as an alternative to local regeneration with a huge amount of funding. The starting point of this study is the public architecture that can be used as a strategic resource for local regeneration as a hub for communities for residents in the local area. The main content of the research is to identify the requirements of public architecture as a local regeneration hub and problems in the current public architecture management system. Based on results of the study, the following direction is to be presented for improvement of the public architecture management system to contribute to continuous local regeneration. The first results reveal there is a need to actively introduce measures to dualize facility maintenance and program operation. Secondly, the results show the participation of residents in public architecture management should be more active to reflect local demand. Thirdly, it is evident that the management entity should establish and implement goals and strategies toward local regeneration. Lastly, public architecture must strive to provide local community space.

• Korean Institute of Interior Design Journal
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• v.19 no.5
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• pp.190-197
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• 2010

This is a study about public-regeneration-architecture design of the 3rd world damaged by the development of capital society of the 20th century and from the perspective of economically poor, anti-capitalist development from non-profit design organization. Active among such non-profit design organizations, the sustainable design characteristics of public-regeneration-architecture of the Architecture for Humanity will be discussed. I help it so as a continuous possibility design to have been given to public-regeneration-architecture of the Architecture for Humanity is small, and I establish a construction space at a few costs to people in a situation to be environmentally interior economic, to be cultural, and I am large, and to be able to generate profitable construction by environment at activation of a local community and worldwide dimensions. I look through a sustainable design way of this study classifies it to cultural sustainability that ecology-cultural approach in the environmental sustainability result ecology - central approach, and how I was applied to materials of construction, color, a pattern, a construction method, space configuration etc. There is the meaning to try to analyze a characteristic of a sustainable design to have appeared to public-regeneration-architecture of the Architecture for Humanity which I make a symbiosis, and you can live on it how in the present cities that city poor floor will add to.

• KIEAE Journal
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• v.16 no.5
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• pp.93-101
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• 2016

Purpose : This research aims to present policy plans for community vitality in the field of the urban regeneration project by analyzing aspects for vitality via domestic and abroad city policies and cases. Methods: The research method works as follows: The first step is 1) to introduce the concept of evaluation matrix to analyze cases of urban generation, 2) to apply to the proposed evaluation matrix, and then 3) to analyze communities' decline diagnosis, counterstrategies, and promotion process. And the second step is to draw features and evaluation of cases and to present the policy plan for communities' vitality with the urban regeneration project in South Korea via a comprehensive analysis. Result : This research confirmed the fact that when different sectors is expanded toward a mutual cooperation, communities are vitalized, having a mutual effect on other related sectors by taking a part in the community positively. Especially in the base of each characteristic and estimation, when various activities and socio-economic programs with residents are promoted in the integrated system, communities are successful. Through this results we present four policy plans for community vitality of the urban regeneration project in South Korea.

• Journal of Periodontal and Implant Science
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• v.31 no.1
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• pp.57-74
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• 2001

The purpose of this study was to evaluate the adjunctive combined effect of demineralized freeze-dried bone allograft(DFDB) in guided bone regeneration on supra-alveo-lar peri-implant defect. Supra-alveolar perio-implant defects, 3mm in height, each including 4 IMZ titanium plasma-sprayed implants were surgically created in two mongrel dogs. Subsequently, the defects were treated with 1 of the following 3 modalities: Control) no membrane or graft application, Group1) DFDB application, Group2) guided bone regeneration using an expanded polytetra-fluoroethylene membrane, Group3) guided bone regeneration using membrane and DFDB. After a healing period of 12-week, the animals were sacrificed, tissue blocks were harvested and prepared for histological analysis. Histologic examination were as follows; 1. New bon formation was minimal in control and Group 1, but considerable new bone formation was observed in Group 2 and Group 3. 2. There was no osteointegration at the implant-bone interface in the high-polished area of group2 and Group 3. 3. In fluorescent microscopic examination, remodeling of new bone was most active during week 4 and week 8. There was no significant difference in remodeling rate between group 2 and group 3. 4. DFDB particles were observed, invested in a connective tissue matrix. Osteoblast activity in the area was minimal. The results suggest that guided bone regeneration shows promising results in supra-alveolar peri-implant defects during the 12 week healing period although it has a limited potential in promoting alveolar bone regeneration in the high-polished area. There seems to be no significant adjunctive effect when DFDB is combined with GBR.

• BMB Reports
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• v.55 no.8
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• pp.401-406
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• 2022

Ahnak, a large protein first identified as an inhibitor of TGF-β signaling in human neuroblastoma, was recently shown to promote TGF-β in some cancers. The TGF-β signaling pathway regulates cell growth, various biological functions, and cancer growth and metastasis. In this study, we used Ahnak knockout (KO) mice that underwent a 70% partial hepatectomy (PH) to investigate the function of Ahnak in TGF-β signaling during liver regeneration. At the indicated time points after PH, we analyzed the mRNA and protein expression of the TGF -β/Smad signaling pathway and cell cycle-related factors, evaluated the cell cycle through proliferating cell nuclear antigen (PCNA) immunostaining, analyzed the mitotic index by hematoxylin and eosin staining. We also measured the ratio of liver tissue weight to body weight. Activation of TGF-β signaling was confirmed by analyzing the levels of phospho-Smad 2 and 3 in the liver at the indicated time points after PH and was lower in Ahnak KO mice than in WT mice. The expression levels of cyclin B1, D1, and E1; proteins in the Rb/E2F transcriptional pathway, which regulates the cell cycle; and the numbers of PCNA-positive cells were increased in Ahnak KO mice and showed tendencies opposite that of TGF-β expression. During postoperative regeneration, the liver weight to body weight ratio tended to increase faster in Ahnak KO mice. However, 7 days after PH, both groups of mice showed similar rates of regeneration, following which their active regeneration stopped. Analysis of hepatocytes undergoing mitosis showed that there were more mitotic cells in Ahnak KO mice, consistent with the weight ratio. Our findings suggest that Ahnak enhances TGF-β signaling during postoperative liver regeneration, resulting in cell cycle disruption; this highlights a novel role of Ahnak in liver regeneration. These results provide new insight into liver regeneration and potential treatment targets for liver diseases that require surgical treatment.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.43 no.3
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• pp.231-238
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• 2010

The Induction of regeneration and maturation in the free-living gametophytes of Ecklonia stolonifera Okamura was studied at four temperatures (5, 10, 15, and $20^{\circ}C$), four levels of irradiance (5, 10, 20, and 40 ${\mu}mol\;m^{-2}s^{-1}$) and three photoperiods (14:10, 12:12, and 10:14 h L:D). Female gametophyte fragments were maintained in active regeneration without reaching sexual maturity under $5{\sim}10^{\circ}C$, 10 ${\mu}mol\;m^{-2}s^{-1}$, 10:14 h (L:D), whereas the conditions for male gametophytes were slightly different at $20^{\circ}C$, 40 ${\mu}mol\;m^{-2}s^{-1}$, 10:14 h (L:D). The sexual maturation of female and male gametophytes was facilitated at $15^{\circ}C$, 20 ${\mu}mol\;m^{-2}s^{-1}$, 14:10 h (L:D). These results provide basic information for controlling the regeneration and maturation of the free-living gametophytes for artificial seed production of E. stolonifera.

• Journal of Digital Convergence
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• v.19 no.7
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• pp.319-325
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• 2021

The urban regeneration project is an activity that promotes the economy in underdeveloped commercial or residential areas and maintains urban communities through improvement of living in residential areas. Through this study, various successful cases of urban regeneration at home and abroad and surveys related to urban regeneration in Bongsan Village, Yeongdo, Busan were collected and analyzed. Key keywords for each case were derived, grouped, and top keywords were created. The 13 top keywords were evaluated using Likert's 5-point scale, and AHP was conducted for the 10 keywords that were finally selected. As a result of AHP analysis, the preference for "spatial and physical properties" was derived in the order of "publicity", "sustainability", and "identity". The preference of "content and system properties" was derived in the order of "resident participation", "convenience", "locality", and "local government participation". It is necessary to present a role as a design guideline for establishing urban regeneration designs in relation to various urban regeneration projects that will become more active in the future through the analysis of preferences of urban regeneration keywords derived through this study.