• Title/Summary/Keyword: Active failure

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Effects of Sophorae Radix Fractionations on Cardiovascular Anaphylaxis in Pithed Rats (고삼 전탕액 분획물이 순환기 Anaphylaxis에 미치는 영향)

  • 권강범;김구환;전영석;조현익;김영석;박관하;백승화;류도곤
    • The Journal of Korean Medicine
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    • v.21 no.2
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    • pp.37-42
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    • 2000
  • Objectives and Methods : Unlike respiratory anaphylaxis responses, mediators responsible for cardiovascular responses are not clearly elucidated. Main characteristics of cardiovascular anaphylaxis include hypotension and cardiac failure (anhythmia and cardiac contraction failure). In this experiment, the fractionations of Sophorae Radix (SR) were tested for its preventive effects against cardiovascular anaphylaxis in pithed rats. Results : Of the SR fractionations, water fractions, at the concentration of 20 and 60mg/kg, was significantly effective on all the cardiovascular changes in pithed rats. Also, of the cardiovascular changes, depressor response was significantly attenuated by the ethyl acetate (EA) fraction, at the concentration of 60mg/kg. Conclusions : These results suggest that water and EA fractions of the SR fractionations possess anti. anaphylactic effects in pithed rats. Additional research is needed to identify active principles for the observed pharmacological effects.

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Overturning Resistance of Plain Concrete Piers in OSPG Railroad Bridges

  • Rhee, In-Kyu;Park, Joo-Nam;Choi, Eun-Soo
    • International Journal of Railway
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    • v.3 no.1
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    • pp.1-6
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    • 2010
  • The steel plate-girder bridges with concrete gravity piers have possibilities of overturning by lateral inertial force which can be reproduced by sudden earthquake attack. This paper explores an overturning mechanism of existing concrete gravity pier onto the sandy soil in the event of lateral push-over load by in-situ experimental observation. The in-situ push-over experiment for pier with earth anchors between spread footing and rock beds exhibits a reasonable enhancement of ductility against overturning. In unanchored system, a flexural crack at cold joint of concrete pier is not developed because of the over-turning of the pier. This leads a global instability (rotation) of pier-footing system with relatively low stresses in pier itself. While a lateral load is persistently increased in anchored system, the successive flexural cracking failure at cold joint is observed even after the local shear failure of soil due to redistribution of stress equilibrium between soil and pier structure as long as a tensile action of anchor cable is active.

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An Analysis on Success and Failure Factors of Domestic and Foreign Businesses Using Social Network Service (SNS를 활용한 국내외 비즈니스의 성공요인과 실패요인 분석)

  • Kim, Chang Su;Kim, Tae Hyun;Park, Gyeong Won
    • Journal of Korea Society of Digital Industry and Information Management
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    • v.10 no.2
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    • pp.229-240
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    • 2014
  • While the digital environment continues to diffuse rapidly, SNS has been playing important roles in business growth. This study analyzes businesses that have used social network services (SNS) in order to more successfully manage companies by utilizing SNS and to suggest the proper steps In order to accomplish this, major domestic and foreign business cases were selected in order to investigate factors of success and failure for each of them. The analysis results show that the companies that utilized SNS successfully understood the characteristics of SNS and constantly tried creative marketing. On the other hand, enterprises that failed to use SNS properly showed low understanding of SNS and abnormal ways of marketing. Therefore, this research suggests the following conclusion. First of all, sufficient knowledge and understanding of the characteristics of SNS are necessary in order to properly utilize SNS. Next, it is imperative to use SNS not only as a tool to communicate with customers, but also to understand the generations that use SNS. Finally, it would be best to implement a more open wireless internet mobile environment for more active use of SNS.

Result of Surgical Treatment for Infective Endocarditis (심내막염의 수술적 치료 성적에 관한 보고)

  • Kim, S.H.;Ahn, H.;Kim, C.W.
    • Journal of Chest Surgery
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    • v.23 no.2
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    • pp.370-376
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    • 1990
  • From April, 1981, through March, 1989, 30 patients had received valve replacements and 1 patient had received foreign body removal for infective endocarditis at Seoul National University Hospital. There were 22 male and 9 female patients, ranged in age from 22 to 59 [mean 34.9] years. Twenty-three had native valve endocarditis, 7 had prosthetic valve endocarditis and 1 had infected transvenous permanent pacemaker electrode in right heart. Twenty-four required operation during active phase of disease and 7 during inactive phase. The infecting organism was Streptococcus in 10 patients, Staphylococcus in 5 patients, both Staphylococcus and Streptococcus in 1 patient, E. coli in 2 patients, and Candida in 1 patient. Indications for Surgery were congestive heart failure in 20, systemic emboli in 5, combination of both in 3, congestive heart failure with uncontrolled sepsis in 2, and complete heart block in 1 patient. Hospital mortality was 9.7% [3/31], and all were the patients who received emergency operation. There were 2 late mortality [7.7 %] due to acute myocardial infarction and recurrent endocarditis. This report suggests that the surgical treatment can be achieved with acceptable low mortality and morbidity in medically intractable congestive heart failure, emboli and sepsis.

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Hardness and adhesion of the reactively sputtered Zr-ZrN on the stainless steel(SUS304) and tool steel(SKH9) (스테인레스와 공구강 위에 스퍼터링된 Zr-ZrN 코팅층의 경도 및 밀착성에 대한 연구)

  • 예길촌;신현준;권식철;백원승
    • Journal of Surface Science and Engineering
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    • v.26 no.6
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    • pp.316-326
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    • 1993
  • Adhesion and hardeness are the most important properties of a hard coated layer which is applied to wear-resistant devices. Zr/ZrN layer was deposited on tool steel(SKH9) and stainless steel(SUS304) by a re-active D.C. magnetron sputtering technique and their microhardness and adhesion strength were measured for the films processed by changing the partial pressures of $N_2$ gas (4~10$\times$$10^{-4}$mbar) and the substrate bias voltage(0~250V). The adhesion strength was evaluated by acoustic signals through the scratch-test with the incremental applied load. As the partial pressure of $N_2$ gas and the substrate bias voltage were increased, the adhesion strength of tool steel was observed to be stronger than that of the stainless steel. The adhesion strength was generally, observed to decrease with the same tendency regardless of the kinds of substrates. The adhesion strength of tool steel was increased more and more strongly than that of stainless steel as heat-treated temperature was increased. The strength of tool steel was appeared to be high adhesion strength at $400^{\circ}C$. From the failure mode of the film during the scratch adhesion test, the cohesive failure was observed to be obvious and the adhesive failure in a minor portion in the Zr/ZrN doublelayer regardless of the kinds of substrates.

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Palliative and end-of-life care for heart failure patients in an aging society

  • Okumura, Takahiro;Sawamura, Akinori;Murohara, Toyoaki
    • The Korean journal of internal medicine
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    • v.33 no.6
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    • pp.1039-1049
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    • 2018
  • The populations of Asian countries are expected to age rapidly in the near future, with a dramatic increase in the number of heart failure (HF) patients also anticipated. The need for palliative and end-of-life care for elderly patients with advanced HF is currently recognized in aging societies. However, palliative care and active treatment for HF are not mutually exclusive, and palliative care should be provided to reduce suffering occurring at any stage of symptomatic HF after the point of diagnosis. HF patients are at high risk of sudden cardiac death from the early stages of the disease onwards. The decision of whether to perform cardiopulmonary resuscitation in the event of an emergency is challenging, especially in elderly HF patients, because of the difficulty in accurately predicting the prognosis of the condition. Furthermore, advanced HF patients are often fitted with a device, and device deactivation at the end of life is a complicated process. Treatment strategies should thus be discussed by multi-disciplinary teams, including palliative experts, and should consider patient directives to address the problems discussed above. Open communication with the HF patient regarding the expected prognosis, course, and treatment options will serve to support the patient and aid in future planning.

Controller Backup and Replication for Reliable Multi-domain SDN

  • Mao, Junli;Chen, Lishui;Li, Jiacong;Ge, Yi
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.14 no.12
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    • pp.4725-4747
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    • 2020
  • Software defined networking (SDN) is considered to be one of the most promising paradigms in the future. To solve the scalability and performance problem that a single and centralized controller suffers from, the distributed multi-controller architecture is adopted, thus forms multi-domain SDN. In a multi-domain SDN network, it is of great importance to ensure a reliable control plane. In this paper, we focus on the reliability problem of multi-domain SDN against controller failure from perspectives of backup controller deployment and controller replication. We firstly propose a placement algorithm for backup controllers, which considers both the reliability and the cost factors. Then a controller replication mechanism based on shared data storage is proposed to solve the inconsistency between the active and standby controllers. We also propose a shared data storage layout method that considers both reliability and performance. Besides, a fault recovery and repair process is designed based on the controller backup and shared data storage mechanism. Simulations show that our approach can recover and repair controller failure. Evaluation results also show that the proposed backup controller placement approach is more effective than other methods.

Estimation of Mobilized Passive Earth Pressure Depending on Wall Movement in Sand (모래지반에서 벽체의 변위에 따른 수동측토압 산정)

  • Kim, Tae-O;Park, Lee-Keun;Kim, Tae-Hyung
    • Journal of the Korean Geotechnical Society
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    • v.36 no.11
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    • pp.51-60
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    • 2020
  • Estimation of passive earth pressure is an important factor in anchor block, temporary retaining wall and support block of raker that resist lateral earth pressure. In practice, due to ease of use, it is common to estimate the earth pressure using the theory of Coulomb and Rankine, which assumes the failure plane as a straight line. However, the passive failure plane generated by friction between the wall surface and the soil forms a complex failure plane: a curve near the wall and a flat plane near the ground surface. In addition, the limit displacement where passive earth pressure is generated is larger compared to where the active earth pressure is generated. Thus, it is essential to calculate the passive earth pressure that occurs at the allowable displacement range in order to apply the passive earth pressure to the design for structural stability reasons. This study analyzed the mobilized passive earth pressured to various displacement ranges within the passive limit displacement range using the semi-empirical method considering the complex failure plane.

A Simplified Method for Predicting Failure Probability of Pipelines with Corrosion Defects (부식결함을 가진 배관의 파손확률 예측을 위한 단순화된 방법)

  • Lee, Jin-Han;Kim, Young-Seob;Kim, Lae-Hyun
    • Journal of the Korean Institute of Gas
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    • v.14 no.4
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    • pp.31-36
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    • 2010
  • An alternative method is presented for predicting failure probability of pipelines with corrosion defects in this paper. The failure of corroded pipeline occurs when the operating pressure is grater than the remaining strength of the pipeline, and a limit state function can be defined as the differences between the remaining strength and the operating pressure. Then, based on structural reliability theory, we can estimate the failure probability of corroded pipeline, which is dependent on elapsed time of the pipeline with active corrosion defects. In this study, a root finding (RF) method has been adopted to solve the limit state function instead of Monte-Carlo simulation (MCS) method which traditionally has been employed to solve those kinds of problems. The calculation results shows that there are only small differences between the RF and the MCS method but the RF has higher efficiency in calculation than the MCS.

Prediction of Food Franchise Success and Failure Based on Machine Learning (머신러닝 기반 외식업 프랜차이즈 가맹점 성패 예측)

  • Ahn, Yelyn;Ryu, Sungmin;Lee, Hyunhee;Park, Minseo
    • The Journal of the Convergence on Culture Technology
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    • v.8 no.4
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    • pp.347-353
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    • 2022
  • In the restaurant industry, start-ups are active due to high demand from consumers and low entry barriers. However, the restaurant industry has a high closure rate, and in the case of franchises, there is a large deviation in sales within the same brand. Thus, research is needed to prevent the closure of food franchises. Therefore, this study examines the factors affecting franchise sales and uses machine learning techniques to predict the success and failure of franchises. Various factors that affect franchise sales are extracted by using Point of Sale (PoS) data of food franchise and public data in Gangnam-gu, Seoul. And for more valid variable selection, multicollinearity is removed by using Variance Inflation Factor (VIF). Finally, classification models are used to predict the success and failure of food franchise stores. Through this method, we propose success and failure prediction model for food franchise stores with the accuracy of 0.92.