• Title/Summary/Keyword: Active Calibration

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Vitamin C Tablet Assay by Near -Infrared Reflectance spectrometry

  • Kargosha, Kazem;Ahmadi, Hamid;Nemati, Nader
    • Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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    • 2001.06a
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    • pp.4111-4111
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    • 2001
  • When a drug is prepared in a tablet, the active component represents only a small portion of the dosage form. The other components of the formulation include materials to assist in the dissolution, antioxidants, coloring agents and bulk fillers. The tablets are tested using approved testing methods usually involving separation and subsequent quantification of the active component. Tablets may also be tested by near-Infrared Reflectance spectrometry (NIRS). In the present study, based on NIRS and multivariate calibration methods, a novel and precise method is developed for direct determination of ascorbic acid in vitamin C tablet. Two different tablet formulations were powdered in three different sizes, 63-125 ${\mu}{\textrm}{m}$, and examined. Spectral region of 4750-4950 $cm^{-1}$ / was used and optimized for quantitative operations. Partial least squares (PLS) and multiple linear regression (MLR) methods were performed for this spectral region. The results of optimized PLS and MLR methods showed that reproducibility increase with decreasing grain size and standard error of calibration (SEP) of less than 1% w/w of ascorbic acid and a correlation coefficient of 0.998 can be achieved. The PLS method showed better results than MLR. Seven overdose and underdose samples (prepared in the laboratory to match marketed products) were tested by proposed and iodometric standard methods. A correlation between NIRS predicted ascorbic acid values and iodomet.ic values was calculated ($R^2$=0.9950). Finally, the direct analysis of individual intact tablets in their unit-dose packages (Blistering in aluminum and PVC foils) obtained from market were also carried out and a correlation coefficient of 0.9989 and SEP of 0.931% w/w of ascorbic acid were achieved.

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A Development of Reflector for CAL/VAL of SAR Satellite (SAR 위성 검보정을 위한 반사기 개발)

  • Keum, Jung-Hoon;Ra, Sung-Woong
    • Journal of Astronomy and Space Sciences
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    • v.26 no.4
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    • pp.667-676
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    • 2009
  • The payload can be classified as a passive and active type. Generally radar satellite to acquire specific information through various radar images will use the SAR (Synthetic Aperture Radar) as active type payload. the principal of SAR satellite is to receive the signal returned from certain objects and/or surfaces in order to construct an radar image. The data acquired from the satellite in its real orbit shall be needed to perform successful CAL/VAL (Calibration & Validation) because the SAR satellite have to receive the returned signal for SAR image construction. In order to do the above, the returned signal shall be related to ground targets. Especially ground target is the corner reflector (CR) for CAL/VAL. Generally the reflector has various types and shapes. Their selection can be dependent on characteristics and mission objectives of SAR satellite. In this paper, reflector focused on the optimal case and effective case has been studied and then the trihedral corner reflector under this study has been designed and its performance also analyzed.

Magnetic Field Measuring System by using Loop-type Sensor (루우프형 센서를 이용한 자장측정계)

  • Lee, Bok-Hee;Kil, Gyung-Suk;Park, Dong-Hwa
    • Journal of Sensor Science and Technology
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    • v.4 no.2
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    • pp.14-21
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    • 1995
  • This paper deals with the active magnetic field measuring system which can measure the time-varying magnetic fields generated by power installations and lightning discharges. The magnetic field measuring system consists of the loop-type magnetic field sensor and the active integrator operated by a differential amplifier. The theoretical principle and design rule of the time-varying magnetic field measuring device and the calibration apparatus are introduced. From the calibration experiments, the frequency bandwidth of the full measuring system ranges from 270 Hz to about 2.3 MHz and the response sensitivity for magentic field strength is 128 $mV/{\mu}T$, respectively, and the calculated B-field values in the center of the loop-type sensor versus the the applied current made with a region of ${\pm}3\;%$error. The actual survey experiments by using lightning impulse current and oscillating impulse current were performed, the results of comparision between the input current waveforms and the magnetic field waveforms are a good agreement with each others and their deviations are less than 0.5 %.

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AN EXTENSION OF A RELIABLE WAVELENGTH COVERAGE OF THE AKARI NG GRISM MODE

  • Baba, Shunsuke;Nakagawa, Takao;Isobe, Naoki;Shirahata, Mai;Ohyama, Youichi;Yano, Kenichi;Kochi, Chihiro
    • Publications of The Korean Astronomical Society
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    • v.32 no.1
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    • pp.45-47
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    • 2017
  • The Infrared Camera onboard the AKARI satellite carried out spectroscopic observations with a grism mode named NG, whose wavelength coverage was $2.5-5.0{\mu}m$. We reinvestigate the current flux calibration for the NG grism mode, with which calculated flux density implausibly decreases at $4.9{\mu}m$ especially for red objects due to the second-order light contamination. We perform a new spectral response calibration using blue and red standard objects simultaneously. New response curves which contain both the first-and second-order light are able to separate each contribution consistently and useful for studies of red objects such as CO ro-vibrational absorption in active galactic nuclei.

INTEGRATED OPTICAL MODEL FOR STRAY LIGHT SUPPRESSION AND END-TO-END PERFORMANCE SIMULATION FOR GOCI

  • Ham, Sun-Jeong;Lee, Jae-Min;Youn, Heong-Sik;Kang, Gm-Sil;Kim, Seong-Hui;Kim, Sug-Whan
    • Proceedings of the KSRS Conference
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    • v.1
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    • pp.274-277
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    • 2006
  • KARI is currently developing a geostationary ocean color imager (GOCI) for COMS. We report the progress in integrated optical modeling and analysis for stray light suppression and the end-to-end instrument performance verification including in-orbit calibration. The Sun is modeled as the emitting light source and the selected area around Korean peninsular as the observation target that scatters the sun light towards GOCI in orbit. The optical ray tracing employing active geometric scaling was then used for precise characterization of the spatial and radiometric performance at the instrument focal plane. The analysis results show positive reduction in the simulated stray light level with the design improvement including baffles. It also indicates that the ray traced in-orbit radiometric performances are effective tools for the independent assessment of more traditional linear and quadratic equation based estimation of water leaving radiance. The concept of integrated GOCI optical model and the computational method are presented.

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CONTINUOUS PERSON TRACKING ACROSS MULTIPLE ACTIVE CAMERAS USING SHAPE AND COLOR CUES

  • Bumrungkiat, N.;Aramvith, S.;Chalidabhongse, T.H.
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2009.01a
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    • pp.136-141
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    • 2009
  • This paper proposed a framework for handover method in continuously tracking a person of interest across cooperative pan-tilt-zoom (PTZ) cameras. The algorithm here is based on a robust non-parametric technique for climbing density gradients to find the peak of probability distributions called the mean shift algorithm. Most tracking algorithms use only one cue (such as color). The color features are not always discriminative enough for target localization because illumination or viewpoints tend to change. Moreover the background may be of a color similar to that of the target. In our proposed system, the continuous person tracking across cooperative PTZ cameras by mean shift tracking that using color and shape histogram to be feature distributions. Color and shape distributions of interested person are used to register the target person across cameras. For the first camera, we select interested person for tracking using skin color, cloth color and boundary of body. To handover tracking process between two cameras, the second camera receives color and shape cues of a target person from the first camera and using linear color calibration to help with handover process. Our experimental results demonstrate color and shape feature in mean shift algorithm is capable for continuously and accurately track the target person across cameras.

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Design and Evaluation of the Control Performance of a Compliant Arm Support (중력 보상 팔 기능 지지대의 설계 및 제어 성능 평가)

  • Kim, Sang-Hun;Jeong, Useok;Park, Daegeun;Koo, Inwook;Cho, Kyu-Jin
    • Journal of the Korean Society for Precision Engineering
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    • v.34 no.2
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    • pp.115-123
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    • 2017
  • This paper presents the design and the control performance of a novel dynamic compliant-arm support with parallel elastic actuators that was developed to assist with the daily living activities of those whose arms are compromised by muscular disease or the aging process. The parallel elastic-arm support consists of a compliant mechanism with combined passive and active components for human interaction and to reach the user's desired positions. The achievement of these tasks requires impedance control, which can change the virtual stiffness, damping coefficients, and equilibrium points of the system; however, the desired-position tracking by the impedance control is limited when the end-effector weight varies according to the equipping of diverse objects. A prompt algorithm regarding weight calibration and friction compensation is adopted to overcome this problem. A result comparison shows that, by accurately assessing the desired workspace, the proposed algorithm is more effective for the accomplishment of the desired activities.

Design and fabrication of an optimized Rogowski coil for plasma current sensing and the operation confidence of Alvand tokamak

  • Eydan, Anna;Shirani, Babak;Sadeghi, Yahya;Asgarian, Mohammad Ali;Noori, Ehsanollah
    • Nuclear Engineering and Technology
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    • v.52 no.11
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    • pp.2535-2542
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    • 2020
  • To understand the fundamental parameters of Alvand tokamak, A Rogowski coil with an active integrator was designed and constructed. Considering the characteristics of the Alvand tokamak, the structural and electrical parameters affecting the sensor function, were designed. Calibration was performed directly in the presence of plasma. The sensor has a high resistance against interference of external magnetic fields. Plasma current was measured in various experiments. Based on the plasma current profile and loop voltage signal, the time evolution of plasma discharge was investigated and plasma behavior was analyzed. Alvand tokamak discharge was divided into several regions that represents different physical phenomena in the plasma. During the plasma discharge time, plasma had significant changes and its characteristic was not uniform. To understand the plasma behavior in each of the phases, the Rogowski sensor should have sufficient time resolution. The Rogowski sensor with a frequency up to 15 kHz was appropriate for this purpose.

NEAR INFRARED TRANSFLECTANCE SPECTROSCOPY (NIRS) IN PHYTOCHEMISTRY

  • Huck, C.W.;W.Guggenbichler;Bonn, G.K.
    • Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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    • 2001.06a
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    • pp.3114-3114
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    • 2001
  • During the last years phytochemistry and phytopharmaceutical applications have developed rapidly and so there exists a high demand for faster and more efficient analysis techniques. Therefore we have established a near infrared transflectance spectroscopy (NIRS) method that allows a qualitative and quantitative determination of new polyphenolic pharmacological active leading compounds within a few seconds. As the NIR spectrometer has to be calibrated the compound of interest has at first to be characterized by using one or other a combination of chromatographic or electrophoretic separation techniques such as thin layer chromatography (TLC), high performance liquid chromatography (HPLC), capillary electrophoresis (CE), gas chromatography (GC) and capillary electrochromatography (CEC). Both structural elucidation and quantitative analysis of the phenolic compound is possible by direct coupling of the mentioned separation methods with a mass spectrometer (GC-MS, LC-MS/MS, CE-MS, CEC-MS) and a NMR spectrometer (LC-NMR). Furthermore the compound has to be isolated (NPLC, MPLC, prep. TLC, prep. HPLC) and its structure elucidated by spectroscopic techniques (UV, IR, HR-MS, NMR) and chemical synthesis. After that HPLC can be used to provide the reference data for the calibration step of the near infrared spectrometer. The NIRS calibration step is time consuming, which is compensated by short analysis times. After validation of the established NIRS method it is possible to determine the polyphenolic compound within seconds which allows to raise the efficiency in quality control and to reduce costs especially in the phytopharmaceutical industry.

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Real Time Gaze Discrimination for Human Computer Interaction (휴먼 컴퓨터 인터페이스를 위한 실시간 시선 식별)

  • Park Ho sik;Bae Cheol soo
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.30 no.3C
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    • pp.125-132
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    • 2005
  • This paper describes a computer vision system based on active IR illumination for real-time gaze discrimination system. Unlike most of the existing gaze discrimination techniques, which often require assuming a static head to work well and require a cumbersome calibration process for each person, our gaze discrimination system can perform robust and accurate gaze estimation without calibration and under rather significant head movement. This is made possible by a new gaze calibration procedure that identifies the mapping from pupil parameters to screen coordinates using generalized regression neural networks (GRNNs). With GRNNs, the mapping does not have to be an analytical function and head movement is explicitly accounted for by the gaze mapping function. Futhermore, the mapping function can generalize to other individuals not used in the training. To further improve the gaze estimation accuracy, we employ a reclassification scheme that deals with the classes that tend to be misclassified. This leads to a 10% improvement in classification error. The angular gaze accuracy is about 5°horizontally and 8°vertically. The effectiveness of our gaze tracker is demonstrated by experiments that involve gaze-contingent interactive graphic display.