• Title/Summary/Keyword: Active Administration

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Solar Flare Occurrence Rate and Probability in Terms of the Sunspot Classification Supplemented with Sunspot Area and Its Changes

  • Lee, Kangjin;Moon, Yong-Jae;Lee, Jin-Yi;Lee, Kyoung-Sun;Na, Hyeonock;Kim, Haeyeon;Shin, Dae-Yun
    • The Bulletin of The Korean Astronomical Society
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    • v.37 no.2
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    • pp.123.2-123.2
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    • 2012
  • We investigate the solar flare occurrence rate and daily flare probability in terms of the sunspot classification supplemented with sunspot area and its changes. For this we use the NOAA active region data and GOES solar flare data for 15 years (from January 1996 to December 2010). We consider the most flare-productive eleven sunspot classes in the McIntosh sunspot group classification. Sunspot area and its changes can be a proxy of magnetic flux and its emergence/cancellation, respectively. We classify each sunspot group into two sub-groups by its area: "Large" and "Small". In addition, for each group, we classify it into three sub-groups according to sunspot area changes: "Decrease", "Steady", and "Increase". As a result, in the case of compact groups, their flare occurrence rates and daily flare probabilities noticeably increase with sunspot group area. We also find that the flare occurrence rates and daily flare probabilities for the "Increase" sub-groups are noticeably higher than those for the other sub-groups. In case of the (M+X)-class flares in the 'Dkc' group, the flare occurrence rate of the "Increase" sub-group is three times higher than that of the "Steady" sub-group. Our results statistically demonstrate that magnetic flux and its emergence enhance the occurrence of major solar flares.

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Evaluation of Total Parenteral Nutrition in Tertiary Hospital (3차병원에서의 TPN 사용의 적정성 점토)

  • Min, Kyoung A;Sohn, Ki Ho;Suh, Ok Kyung;Choi, Kyung Eob
    • Korean Journal of Clinical Pharmacy
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    • v.8 no.1
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    • pp.35-46
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    • 1998
  • A retrospective study was conducted to evaluate the appropriateness of total parenteral nutrition (TPN) for 200 hospitalized adult patients in Samsung Medical Center from January 1st in 1995 to June 31st in 1997. Standard criteria were modified and determined from those stated by AJHP (American Journal of Health System Pharmacy) and ASPEN (American Society of Parenteral and Enteral Nutrition). The justification for indications was appropriate in $35\%,\;44\%,\;and\;32\%$ of the patient's in 1995, 1996, and 1997, respectively, without significant improvement over the last two and half years. Before and during the administration of TPN, several monitoring indicators were well documented, and monitoring frequencies were increased over two and half years period. However, the majority of the monitoring indicators were not found in the standard criteria range of $90\%$. The monitoring indicators for electrolyte balance, $PO_4$ and Mg, were not measured appropriately and resulted in the complications which could have been prevented. The indicator for lipid tolerance, triglyceride and the indicator for hemorrhagic incidence, prothrombin time (PT), were not well documented in comparison with other indicators. The indicators for the improvement in nutritional status, albumin and total protein, were appropriate in $90\%$ of the patients. Determination of TPN formula was based on the laboratory data and chart reviews, and it was appropriate in $98\%$. But the administration of lipid and vitamin K for the prevention of essential fatty acid deficiency and hemorrhage, respectively, was not carried out appropriately when the administration of TPN was prolonged, lasting more than 7 days. When a patient returned to oral or enteral feeding, TPN was terminated. However, increase in albumin level or weight was rarely observed. In conclusion, healthcare professionals should all work as a team and active participation to provide optimized nutrition support for partners.

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Protective role of caffeic acid in an Aβ25-35-induced Alzheimer's disease model

  • Kim, Ji Hyun;Wang, Qian;Choi, Ji Myung;Lee, Sanghyun;Cho, Eun Ju
    • Nutrition Research and Practice
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    • v.9 no.5
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    • pp.480-488
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    • 2015
  • BACKGROUND/OBJECTIVES: Alzheimer's disease (AD) is characterized by deficits in memory and cognitive functions. The accumulation of amyloid beta peptide ($A{\beta}$) and oxidative stress in the brain are the most common causes of AD. MATERIALS/METHODS: Caffeic acid (CA) is an active phenolic compound that has a variety of pharmacological actions. We studied the protective abilities of CA in an $A{\beta}_{25-35}$-injected AD mouse model. CA was administered at an oral dose of 10 or 50 mg/kg/day for 2 weeks. Behavioral tests including T-maze, object recognition, and Morris water maze were carried out to assess cognitive abilities. In addition, lipid peroxidation and nitric oxide (NO) production in the brain were measured to investigate the protective effect of CA in oxidative stress. RESULTS: In the T-maze and object recognition tests, novel route awareness and novel object recognition were improved by oral administration of CA compared with the $A{\beta}_{25-35}$-injected control group. These results indicate that administration of CA improved spatial cognitive and memory functions. The Morris water maze test showed that memory function was enhanced by administration of CA. In addition, CA inhibited lipid peroxidation and NO formation in the liver, kidney, and brain compared with the $A{\beta}_{25-35}$-injected control group. In particular, CA 50 mg/kg/day showed the stronger protective effect from cognitive impairment than CA 10 mg/kg/day. CONCLUSIONS: The present results suggest that CA improves $A{\beta}_{25-35}$-induced memory deficits and cognitive impairment through inhibition of lipid peroxidation and NO production.

Determination of tyrosinase inhibitory activity and betanin content changes in beetroot (Beta vulgaris) extracts fermented by EM

  • Yoo, Jong Hee;Kim, Hyun Ki;Yoon, Tae Wou;Mekapogu, Manjulatha;Ahn, Myung Suk;Kwon, Oh Keun;Bang, Keuk Soo;Kim, Yong Ju
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2019.04a
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    • pp.110-110
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    • 2019
  • Beet (Beta vulgaris) is a crop similar to sugar beet, chard and leaf beets, and its origin is the Mediterranean coast of southern Europe and Central Asia. Among the components contained in beet, betalain, the main component of the root, has been reported to prevent lipid peroxidation induced by active oxygen and free radicals due to its high radical scavenging ability. Among these, the betalain, betanin (Betanidin 5-O-${\beta}$-glucoside) contains both phenolic and cyclic amine groups, all of which are highly electron-donating and act as antioxidants and has tyrosinase inhibitory activity. Betanin accounts for about 75-95% of the total pigment found in the beet. EM stands for effective microorganisms and is a collection of beneficial microorganisms. EM includes yeast, lactic acid bacteria, mycelia, photosynthetic bacteria, actinomycetes, etc. Human patch test according to CTFA guidelines was observed to be a safe source of no stimulation when 5% (v/v) of the EM fermentation liquid was applied to the human body. In addition, beneficial microorganisms are synergistic in the process of co-existence and cultivation and it has the effect of increasing antioxidant capacity and inhibiting corruption. This study confirms the difference in tyrosinase inhibitory activity and betanin content of beetroot extracts and EM fermented beetroot extracts. Hence, these results confirm that EM fermented beetroot extracts are highly beneficial for the human body.

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A Study on the Effect of Characteristics of Shopping Mall on Revisit -Focusing on the difference in online platform form- (온라인 쇼핑몰의 특성이 소비자 재방문 의도에 미치는 영향 -온라인 플랫폼 형태 차이를 중심으로-)

  • Shin, Jong-Kuk;Kim, Jea-Hun;Rhee, Sung-Hyun
    • Journal of Digital Convergence
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    • v.19 no.4
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    • pp.73-88
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    • 2021
  • The development of modern industry is changing the consumption pattern of consumers. With the advent of COVID-19, consumers' consumption using online e-commerce has begun to become more active. Online shopping malls where e-commerce takes place have four types of platforms: stand-alone, rental, open market and store farm. Among them, by comparing the stand-alone and store farm types, this study was conducted how the platform type affects consumers' purpose of using the online shopping mall and their intention to revisit the online shopping mall. This study analyzed 202 surveys within the last six months. According to the results of the study, reliability and information had a significant impact on psychological benefits. In addition, promotion and convenience have had a significant impact on economic benefits. The psychological and economic benefits, have been found to have a significant impact on the intention of revisit. However, there is no difference depending on the platform type.

Characteristics and Control of Pear Scab (Venturia nashicola): A Review (배 검은별무늬병균(Venturia nashicola) 감염특성과 방제기술)

  • Eu Ddeum Choi;Janghoon Song;Ho-Jin Seo
    • Research in Plant Disease
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    • v.29 no.2
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    • pp.101-107
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    • 2023
  • Pear scab, caused by Venturia nashicola, is one of the most devastating diseases of Asian pears in Korea, Japan, China, and Taiwan. To manage this disease, growers mainly relied on chemical control. However, continuous use of chemical causes not only environmental contaminant but also the emergence of resistance to pathogens, so a more sustainable management plan is needed. Therefore, it is necessary to understand the life cycle and infection characteristics of V. nashicola and to set an active control strategy according to meteorological conditions rather than, as in the past, calendar-based control or continuous use of a specific fungicide system. Various results of the related research results were reviewed to summarize the race, infection characteristics, and control system of V. nashicola, a pear scab, and to discuss plans for a more effective control system.

An Empirical Study on the Effectiveness of Marketing Activities for Ethical Drugs (ETC) (전문의약품 마케팅활동의 효과 측정에 관한 실증 연구)

  • Seung-Yeoun Noh;Keun-Woo Kim;Nam-Sik Chang
    • Asia-Pacific Journal of Business
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    • v.14 no.4
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    • pp.289-303
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    • 2023
  • Purpose - The purpose of this study is to investigate the types and forms of various marketing activities actually used in pharmaceutical companies and to empirically analyze the impact of these marketing activities on sales. Design/methodology/approach - This study categorize five years' worth of marketing activity data from a foreign pharmaceutical company 'A' which operates in South Korea into five categories. Multiple regression analysis and interaction effects are employed for data analysis. Findings - First, CRM calls, Detail calls, GP, and Web events have a positive impact on sales, but SoV does not show significant differences. Second, in the comparison between HQ1 and HQ2 based on patent ownership, Detail calls and Web events had a stronger impact on sales in HQ2, where the patent period is still in effect, compared to HQ1. However, SoV showed no difference between HQ1 and HQ2. Research implications or Originality - First, Detail Calls are more effective for drugs with active patents, while CRM Calls work better for drugs with expired patents. This emphasizes the need to customize call strategies based on patent status. Second, the significant impact of Web Events on sales in HQ2 compared to HQ1 suggests that online information access is crucial, indicating that customer receptivity varies based on product nature. Third, these insights, derived from data analysis, call for a shift in pharmaceutical marketing analysis methods away from traditional approaches. Finally, this study holds significance as one of the first empirical analyses using actual marketing data from pharmaceutical companies in South Korea.

Records Culture and Local autonomy (기록문화와 지방자치)

  • Lee, Young-Hak
    • The Korean Journal of Archival Studies
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    • no.26
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    • pp.63-93
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    • 2010
  • This document illustrates the culture of archives should be improved to get better in local autonomy. In 1994, the municipal elections were held to perform autonomous activities in Korea. It has been sixteen years, since the first municipal election had been held. The local autonomy can be accomplished well, based on the economic independence from the central government and growing awareness of locals. Not only that, if local records were well archived and suitably used, autonomy could be more active. However, since the independence from Japan in 1945, records of the self-government has not been archived well. Not only archives of local government have not been established, but also organization, budget and professional staff have not been arranged well. This brought about local records administration's inactive performance. As a result, numerous number of meaningful records are lost and people are difficult to make out the local administration policy. If the records of local government preserved well, administrative efficiency, responsibility, transparency can be realized in better way. When local officials' work experiences and achievements were on record and referred to a successor of officials properly, administrative efficiency would be highly promoted. In addition, with the well-preserved work records, people are able to see where the responsibility lies. A local autonomous entity might be able to obtain administrative transparency by showing administrative processes and results to locals to the public. In this manner, the premise to archive the records of local autonomous entity is to establish a department which can archive local records and the disposition of professional archivists. According to "the law on public archives management", the governor of a province should discuss with a minister of administration to set up plans for archives' establishment and management. In this way, local archives administration would work well, when not only the department of local records administration is established, but also the department of local archives places local records under their control at the same time. Moreover, based on active records movement, municipal officials and locals would realize the importance of local record and examine local records administration systems. Not only that, when local records are shown to public and utilized properly, the local autonomy would improve a lot.

Classification of Crop Cultivation Areas Using Active Learning and Temporal Contextual Information (능동 학습과 시간 문맥 정보를 이용한 작물 재배지역 분류)

  • KIM, Ye-Seul;YOO, Hee-Young;PARK, No-Wook;LEE, Kyung-Do
    • Journal of the Korean Association of Geographic Information Studies
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    • v.18 no.3
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    • pp.76-88
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    • 2015
  • This paper presents a classification method based on the combination of active learning with temporal contextual information extracted from past land-cover maps for the classification of crop cultivation areas. Iterative classification based on active learning is designed to extract reliable training data and cultivation rules from past land-cover maps are quantified as temporal contextual information to be used for not only assignment of training data but also relaxation of spectral ambiguity. To evaluate the applicability of the classification method proposed in this paper, a case study with MODIS time-series vegetation index data sets and past cropland data layers(CDLs) is carried out for the classification of corn and soybean in Illinois state, USA. Iterative classification based on active learning could reduce misclassification both between corn and soybean and between other crops and non crops. The combination of temporal contextual information also reduced the over-estimation results in major crops and led to the best classification accuracy. Thus, these case study results confirm that the proposed classification method can be effectively applied for crop cultivation areas where it is not easy to collect the sufficient number of reliable training data.

Antimicrobial Activity of Ethanol Extracts from Medicinal Herbs and Its Active Compound against Plant Pathogens (한약재 주정추출물과 그 유효성분의 식물병원균에 대한 항균활성)

  • Yang, Ji-Yeon;Ryu, Song-Hee;Lim, Sung-Jin;Choi, Geun-Hyoung;Park, Byung-Jun
    • Korean Journal of Environmental Agriculture
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    • v.35 no.3
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    • pp.191-201
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    • 2016
  • BACKGROUND: The aim of this study was to investigate the antimicrobial effects of the ethanol extracts from various medicinal herbs against plant pathogens to understand the possible the crop protection agents.METHODS AND RESULTS: Among the tested medicinal herbs, Zizyphus jujuba ethanol extract had the potent antimicrobial activity against Phytophthora capsici, Erwinia carotovorum subsp. carotovora, Pseudomonas syringae pv. syringae and Ralstonia solanacearum. The major constituents of Z. jujuba were identified to eugenol(40.45%), dodecanoic acid(18.40%), β-caryophyllene (10.05%) and isoeugenol(9.85%) by GC/MS. Eugenol and isoeugenol had strong inhibitory activity on spore germination against P. capsici and growth against E. carotovorum subsp. carotovora, P. syringae pv. syringae and R. solanacearum.CONCLUSION: In this regard, eugenol and isoeugenol were found to be responsible for the antimicrobial activity of Z. jujuba ethanol extract against plant pathogens. In addition, Z. jujuba ethanol extract, eugenol and isoeugenol can be used the potent antimicrobial agents.