• The Korea Journal of Herbology
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• v.24 no.3
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• pp.161-167
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• 2009

Objectives : Maekmoondong-tang (MMDT), a Korean herbal medicine, has been used to treat severe dry cough in patients with bronchitis and pharyngitis. MMDT has been reported to have anti-inflammatory, anti-allergic, immunomodulatory, secretory-modulating, and metabolic regulatory actions. However, there are no evidence in regard to the effects of MMDT on carcinogenesis and metastasis. Here, we investigated the effects of 70% ethanol extract of MMDT on cell viability, apoptosis, and motility in human hepatocarcinoma HepG2 cells. Methods : Cell viability was measured using the CCK-8 assay, and the apoptosis induction was evaluated by caspase-3 activity. To detect apoptotic features, the cells treated with MMDT were stained with 4'-6-diamidino-2-phenylindole (DAPI). Cell motility was examined by Boyden chamber assay and Real-time Cell Index of Migration assay. Gelatin zymography also performed to measure matrix metalloproteinase (MMP)-2/9 activity. Results : We found that MMDT significantly inhibited cell proliferation and increased caspase-3 activity in a dose-dependent manner in HepG2 cells. Apoptotic features such as chromatin condensation and apoptotic bodies were observed in MMDT-treated cells by DAPI staining. MMDT also suppressed PMA-induced cell motility and activities of MMP-2/9. Conclusions : Our results exhibited that MMDT possess the anti-carcinogenetic and anti-metastatic activities via caspase-3 activation and down-regulation of cell motility and invasion in HepG2 cells. Therefore, these findings suggest that MMDT could be potentially applied to the prevention and treatment of cancer.

• Journal of Naturopathy
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• v.12 no.1
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• pp.16-23
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• 2023

Background: There is a need for index research on music therapy activities for the elderly in Korea. Purposes: This study aims to suggest application standards in music therapy by surveying the elderly's preference for music therapy activities. Methods: A survey of music-related actions and musical instrument preferences was conducted with 91 older people in 4 nursing homes. The questionnaire consisted of information about music activities, genres of songs, types of instruments, methods of movement, and purpose of participation in activities. Results: The preference for musical activities was for playing musical instruments, followed by singing, music appreciation, flowing movements, and concert-oriented activities. Music genres appeared in the order of popular songs, folk songs, and children's songs. The instrument type preferred drums, followed by shakers and woodblocks. As a movement application method, movement using themes is preferred. Participating in music activities was leisure, followed by stress relief and emotional cultivation. Conclusion: When applying music therapy to the elderly, it predicted that the treatment effect would be high when the elderly focus on playing musical instruments and singing activities preferred by the elderly. Music genres selected from popular music and folk songs, and musical instruments are drums and shakers. Therefore, if you use it, you can expect a more significant effect.

• Journal of Internet of Things and Convergence
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• v.9 no.2
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• pp.61-69
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• 2023

In recent years, due to heightened environmental awareness, Electric Power Steering (EPS) has been increasingly adopted as the steering control unit in manufactured vehicles. This has had numerous benefits, such as improved steering power, elimination of hydraulic hose leaks and reduced fuel consumption. However, for EPS systems to respond to actions, sensors must be employed; this means that the consistency of the sensor's linear variation is integral to the stability of the steering response. To ensure quality control, a reliable method for detecting defects and assessing linearity is required to assess the sensitivity of the EPS sensor to changes in the internal design characters. This paper proposes a data-driven defect and linearity assessment monitoring system, which can be used to analyze EPS component defects and linearity based on vehicle speed interval division. The approach is validated experimentally using data collected from an EPS test jig and is further enhanced by the inclusion of a Graphical User Interface (GUI). Based on the design, the developed system effectively performs defect detection with an accuracy of 0.99 percent and obtains a linearity assessment score at varying vehicle speeds.

• The Journal of the Convergence on Culture Technology
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• v.9 no.1
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• pp.717-724
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• 2023

we are investigated the anti-inflammatory effects of Safflower and Mother wort Ethanol Complex Extracts(SEC) on lipopolysaccharide (LPS)-activated RAW 264.7 cells. The results demonstrated that pretreatment of SEC(500㎍/mL) significantly reduced NO production by suppressing iNOS protein expression in LPS-stimulated cells. Anti-inflammatory effects by Safflower and Mother wort Ethanol Complex Extracts were observed in the following. Safflower and Mother wort Ethanol Complex Extracts inhibited the translocation of NF-κB from the cytosol to the nucleus via the suppression of IκB-α phosphorylation and also inhibited LPS-stimulated NF-κB transcriptional activity. These findings suggest that Safflower and Mother wort Ethanol Complex Extracts exert anti-inflammatory actions and help to elucidate the mechanisms underlying the potential therapeutic values of Safflower and Mother wort Ethanol Complex Extracts. Therefore, Safflower and Mother wort Ethanol Complex Extracts could be regarded as a potential source of natural anti-inflammatory agents.

• Journal of Navigation and Port Research
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• v.47 no.1
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• pp.18-24
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• 2023

After the Great East Japan Earthquake, many reports and books that compiled testimonies of adult victims were published. Thus, refugee situations are well known, but information on the refugee situations of Japanese students is not. This is because what actions the students took and how they sought refuge from an earthquake or tsunami have not been fully recognized. The purpose of this study was to examine and analyze students' refuge behavior in the Great East Japan Earthquake and to predict the refuge behavior of students affected by future disasters. The results of the study showed that students passively acquired information about earthquakes and tsunamis and that their refuge behavior was highly dependent on adults. Immediately after an earthquake, people tended to protect themselves and stay in place until the shaking stopped. However, they tended to move to another place after the shaking occurred frequently. Students living on ria coastlines were likely to move to high places to escape the threat of earthquakes and tsunamis, whereas students living in plain regions were likely to move vertically to tall buildings, such as schools. As for the mode of movement to refugee shelters, the students arrived at the final refugee shelters in one move, and it is assumed that the refugee shelters should be decided in advance and the students should move there.

• Nuclear Engineering and Technology
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• v.27 no.6
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• pp.811-824
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• 1995

The CANDU element bowing is attributed to actions of both the thermally induced bending moments and the bending moment due to hydraulic drag and mechanical loads, where the bowing is defined as the lateral deflection of an element from the axial centerline. This paper consider only the thermally-induced bending moments which are generated both within the sheath and the fuel and sheath by an asymmetric temperature distribution with respect to the axis of an element The generalized and explicit analytical formula for the thermally-induced bending is presented in con-sideration of 1) bending of an empty tube treated by neglecting the fuel/sheath mechanical interaction and 2) fuel/sheath interaction due to the pellet and sheath temperature variations, where in each case the temperature asymmetries in sheath are modelled to be caused by the combined effects of (i) non-uniform coolant temperature due to imperfect coolant mixing, (ii) variable sheath/coolant heat transfer coefficient, (iii) asymmetric heat generation due to neutron flux gradients across an element and so as to inclusively cover the uniform temperature distributions within the fuel and sheath with respect to the axial centerline. As the results of the sensitivity calculations of the element bowing with the variations of the parameters in the formula, it is found that the element bowing is greatly affected relatively with the variations or changes of element length, sheath inside diameter, average coolant temperature and its variation factor, pellet/sheath mechanical interaction factor, neutron flux depression factor, pellet thermal expansion coefficient, pellet/sheath heat transfer coefficient in comparison with those of other parameters such as sheath thickness, film heat transfer coefficient, sheath thermal expansion coefficient and sheath and pellet thermal conductivities.

• Journal of Korean Elementary Science Education
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• v.42 no.1
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• pp.64-81
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• 2023

In this study, we analyzed pre-service teachers' levels of pedagogical reasoning while watching video clips of elementary school students' discussions of their conceptions of solution and dissolution. 81 pre-service teachers participated in the study. It was found that many pre-service teachers had scientific conceptions, and pre-service teachers who had non-scientific conceptions showed misconceptions similar to those of elementary school students. In both conceptions, pre-service teachers partially or comprehensively interpreted the students' misconceptions with reference to the evidence. However, the rates of pre-service teachers who misinterpreted or simply restated the students' utterances were quite high. Many pre-service teachers suggested only one factor related to levels of reasoning about causes of misconceptions, and most suggested factors were related to the student factor. The level of reasoning about instructional decisions differed according to dissolution and solution conceptions. Actions linked to students' thinking were more closely related to students' specific thinking than to their generic thinking, and among these, student-centered action was seen. From the above results, we sought ways of improving pre-service teachers' pedagogical reasoning.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.23 no.3
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• pp.145-151
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• 2023

3D-CNN is one of the deep learning techniques for learning time series data. Such three-dimensional learning can generate many parameters, so that high-performance machine learning is required or can have a large impact on the learning rate. When learning dynamic hand-gestures in spatiotemporal domain, it is necessary for the improvement of the efficiency of dynamic hand-gesture learning with 3D-CNN to find the optimal conditions of input video data by analyzing the learning accuracy according to the spatiotemporal change of input video data without structural change of the 3D-CNN model. First, the time ratio between dynamic hand-gesture actions is adjusted by setting the learning interval of image frames in the dynamic hand-gesture video data. Second, through 2D cross-correlation analysis between classes, similarity between image frames of input video data is measured and normalized to obtain an average value between frames and analyze learning accuracy. Based on this analysis, this work proposed two methods to effectively select input video data for 3D-CNN deep learning of dynamic hand-gestures. Experimental results showed that the learning interval of image data frames and the similarity of image frames between classes can affect the accuracy of the learning model.

• Journal of Popular Narrative
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• v.25 no.1
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• pp.123-161
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• 2019

The popularity of melodrama indicates that melodrama is composed in a historical context. This is the reason why it is necessary to analyze the imagination of melodrama within a sociocultural context rather than asking the essentialistic question of "What is melodrama?". (2016) and (2018) caused sensations while holding unchallenged top positions in terms of viewing rate and popularity. These dramas indicate the popular imagination and desire of Korean society in the 2010s during a period of upheaval. This paper analyzed imagination in melodrama with a focus on nation and emotions of individuals in and . In preexisting dramas, conflicts are often limited to individuals and families; on the contrary, in and , a nation appears as a motif that forms conflicts between individuals. In these intense situations of conflict, people make rational judgments at first; however, they soon dispose of such judgments and reveal value-oriented attitudes through emotions, which drive actions. Both dramas form poésie mainly through poetic rhyming and the mise-en-scène of objects. The dramas also amplify emotions. The main emotions of these dramas are sympathy and sadness. Such emotions are not consumed in itself; instead, they show moral aims through performativity. Consequently, sympathy becomes solidarity, and sadness becomes mourning. Unlike preexisting melodramas whose endings were simply pursuits of love and happiness within the realm of individuals, and demonstrate a moral imagination that simultaneously reminds us of the individual and community through solidarity and mourning.

• Journal of Practical Agriculture & Fisheries Research
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• v.20 no.2
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• pp.13-29
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• 2018

Currently, rural labor markets are undergoing a structural change in which the proportion of non-agricultural industries is increasing, instead of decreasing the proportion of agriculture. The purpose of this study is to propose policy for job creation in rural areas through analyzing the employment situation in Rural Korea in the context of this structural change. Using the Census of Agriculture, Farm Household Economy Survey, we analyzed the increase of low income farmers and self-employed farmers. We analyzed the changes of non-farm employment in rural areas using the Census on Establishment. The main results of the study are as follows. First, farms' pathways are very diverse by the levels of income from their own farming and other gainful activities. It is necessary to implement policies that take into account the development pathways of farm household. Second, most of the farms are in low-income and self-employment status. In order to increase their incomes, it is necessary to increase non-farm income earning policy. The rural non-farm economy is becoming increasingly important in rural Korea. The growth of the non-farm economy will be crucially important when it comes to creating new jobs in rural areas in rural Korea. Third, it is necessary to provide systematic support for rural entrepreneurship as a core policy for expanding jobs beyond agriculture. Rural entrepreneurship has the potential to drive innovations that can reduce poverty and create employment. Fourth, there is a need for measures to increase jobs in the welfare field, which is growing fastest in recent years. In the welfare field, we can find vigorous collective actions in some rural communities such as community business, cooperative movement and various community development activities. Those activities will help increase the employment of aged farmers and low-income farm household.