• Molecules and Cells
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• 제39권1호
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• pp.72-76
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• 2016

Cell death pathways such as apoptosis can be activated in response to oxidative stress, enabling the disposal of damaged cells. In contrast, controlled intracellular redox events are proposed to be a significant event during apoptosis signaling, regardless of the initiating stimulus. In this scenario oxidants act as second messengers, mediating the post-translational modification of specific regulatory proteins. The exact mechanism of this signaling is unclear, but increased understanding offers the potential to promote or inhibit apoptosis through modulating the redox environment of cells. Peroxiredoxins are thiol peroxidases that remove hydroperoxides, and are also emerging as important players in cellular redox signaling. This review discusses the potential role of peroxiredoxins in the regulation of apoptosis, and also their ability to act as biomarkers of redox changes during the initiation and progression of cell death.

• 한국정보통신학회논문지
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• 제16권6호
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• pp.1133-1140
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• 2012

우리나라의 지능형 교통체계(ITS)는 "국가통합교통체계효율화법"에 근거한 ITS 사업시행지침 및 각 ITS 표준에 의하여 구축되고 있다. 그러나 주요 ITS 설비에 대한 기술적 특징과 시공 구축에 대한 기술기준이 마련되어 있지 않은 채, 단 몇 개의 사업시행지침과 정보교환기술에 치우쳐 있는 ITS 표준만으로는 스마트한 지능형 교통체계(ITS) 구축을 기대하기 어렵다. 따라서 본 논문에서는 현행 법적 제도의 현황 및 문제점을 파악하고 스마트한 지능형 교통체계(ITS) 구축을 위한 기술기준 제정의 필요성에 대하여 살펴보기로 한다.

• 대한안전경영과학회지
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• 제15권2호
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• pp.9-20
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• 2013

OSHA(Occupational Safety and Health Act) generally regulates employer's business principles in the workplace to maintain safety environment. This act has the fundamental purpose to protect employee's safety and health in the workplace by reducing industrial accidents. Authors tried to investigate the correlation between 'occupational injuries and illnesses' and level of regulation compliance using Survey on Current Status of Occupational Safety & Health data by the various statistical methods, such as generalized regression analysis, logistic regression analysis and poison regression analysis in order to compare the results of those methods. The results have shown that the significant affecting compliance factors were different among those statistical methods. This means that specific interpretation should be considered based on each statistical method. In the future, relevant statistical technique will be developed considering the distribution type of occupational injuries.

• Asian Journal of Innovation and Policy
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• 제10권3호
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• pp.355-379
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• 2021

This study examined the evolution of S&T Basic Acts in Korea from the Science and Technology Promotion Act (1967) through the Special Act on STI (1997) to the Framework Act on Science and Technology (2001) in the following aspects: 1) comprehensive plans, 2) coordination mechanisms for S&T policies, 3) enforcement of R&D programs and performance diffusion, 4) promotion of human resources, 5) and S&T investment and budgeting. Before the Framework Act on S&T was enacted in 2001, critical issues were found in establishing S&T master plans, promotion of R&D programs, comprehensive coordination mechanisms, and R&D budgeting. The three Basic Acts have expanded the scope of regulation over time to cover the entire cycle of the S&T process. They concern a wide range of issues, including creating a basis for scientific and technological development, S&T promotion, disseminating and commercializing research outcomes, and preventing adverse effects from science and technology. The content of the Basic Acts has evolved in response to changes in the political, economic, and social environment of Korean industry during the past five decades.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2011년도 춘계학술대회 논문집
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• pp.1014-1022
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• 2011

Urban transit operation is to manipulate the vehicle or train of urban transit to be operated on the basis of the installations such as track, power, communication, signaling and so on. It can be performed by manual or automated, or manned or manless operation considering its system built, operation efficiency, safety, etc. Because of the heavy impact directly to the safety of passenger transport, it has been managed strictly by the Regulation for Train Operation of Urban Transit according to Urban Transit Act. However, the present regulation has been basis of the manual operation mainly, it is crossing beyond the limitation of application to the manless operation which is being introduced moment to moment. It is needed increasingly to revise the regulation for the manless operation which is close at hand now. In this paper, we examined and analysed the cases of manless operation of urban transit planed within the country such as Busan 4th Line, Shinbundang Line, Busan-Kimhae Line, etc. based on the present regulation, and proposed the review of considerations to reflec the manless operation to the regulation to be revised.

• 기술혁신학회지
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• 제20권4호
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• pp.939-969
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• 2017

환경과 안전에 대한 관심이 증가함에 따라 사회적 규제 및 이의 혁신에 대한 영향성에 대한 관심 또한 증대되고 있다. 포터가설을 중심으로 한 기존의 사회적 규제 관련 문헌들은 주로 혁신으로 인한 비용, 기대이익, R&D 투자 등 내적 요소에 초점을 두어 왔다. 최근에는 환경규제 등 사회적 규제로 인한 산업구조의 변화에 관심을 두는 연구가 증가하고 있는 상황이나, 사회적 규제에 따른 외부환경의 변화와 그로 인한 혁신에 대한 영향에 대해서는 연구가 많이 이루어지지 못한 상황이다. 이에 본 연구에서는 기존 문헌이 제시하는 바와 같이 준수 기대이익 등 내적 요인은 물론, 산업구조 변화와 같은 변화를 통해 사회적 규제가 혁신에 영향을 미칠 수 있음을 보여주고자 하였다. 이를 위해 본 연구에서는 국내 철강 구조물용 내화 피복재 산업의 사례연구를 실시하였다. 연구 결과 내화 피복재 산업은 1990년대 3번에 걸친 규제완화를 경험하였으며, 이들 규제 완화들이 시장 기회 및 기대이익을 제공함으로써 신규 시장진입을 유도하였고, 시장구조 변화와 경쟁 심화에 따라 기업들의 혁신이 발생하였음을 확인할 수 있었다.

• 국제학술발표논문집
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• The 1th International Conference on Construction Engineering and Project Management
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• pp.687-692
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• 2005

The Building and Construction Industry Security of Payment Act 1999 (NSW) (the Act) is a unique form of statutory regulation for the building and construction industry, which gives virtually all industry participants a statutory right to, and a means of recovering, payments for work done under a construction contract. The research aim is to examine current trends in adjudication applications and determinations under the Act. The research reveals: (a) that the adjudication process is encouraging parties to resolve disputes as to payment (b) that there is low level of awareness and understanding of the provisions of the Act, particularly amongst subcontractors; (c) that claimants making small claims experience a high rate of success at adjudication; and (d) that the indirect cost of adjudication is becoming problematic.

• 정보화정책
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• 제19권3호
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• pp.3-18
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• 2012

경제질서라는 헌법적 문제는 어느 국가와 시대를 막론하고 항상 뜨거운 이슈가 되어 왔다. 한국에서도 국가규제의 정도와 수준에 대하여 끊임없는 논쟁이 지속되고 있다. 헌법 제119조는 시장경제질서를 원칙으로 하고 있으며, 예외적으로 시장에 대한 정부의 개입과 조정을 허용하고 있다. 헌법이 국가에게 규제와 조정의 권한을 부여한 것은 기본권의 보장과 실현이라는 최종적 헌법가치를 실현하기 위해서이다. 따라서 국가는 "시장의 자유와 창의"의 수호자로서 또한 경제민주화라는 목표달성을 위한 공정한 조정자와 중재자로서의 역할이 그 소명을 다하여야 한다. 경제헌법이 어떠한 역사적 변천과정을 겪었는지를 살펴 보고, 학설과 판례를 통해 축적된 헌법 제119조의 원리를 분석함으로써, 현재 우리 사회에서 경제헌법이 갖는 의미를 되짚어 보기로 한다. 그리고 최근 개정된 소프트웨어 산업진흥법상의 대기업참여제한제도를 고찰하여 바람직한 국가정책방향을 모색해 보기로 한다.

• 융합보안논문지
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• 제17권4호
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• pp.79-87
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• 2017

뉴욕주에는 미국에서 가장 큰 도시인 뉴욕이 있으며 특히 9 11테러사태 이후 안전은 뉴욕 시민 모두에게 가장 중요한 사안이라 시큐리티에 관심이 높은 곳이다. 본 연구목적은 뉴욕주의 민간경비 관련 법령을 분석하고 평가하여 한국에 접목할 수 있는 시사점을 찾아서 제시하는 것이다. 시사점은 첫째, 전문 법규의 운영과 다양한 자격제도이다. 둘째, 밀접한 민 관 협력 연계이다. 셋째, 전문적인 경비업단체의 활동이다.

• 한국안전학회지
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• 제31권3호
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• pp.116-122
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• 2016

With the changes of industrial structure, contents and types in hazardous and dangerous works have been changed considerably. However, the hazardous and dangerous works by defined "Regulation for the hazardous and dangerous work employment restriction" and "Special education for safety and health"have not been amended over twenty years. This study aimed to identify the recent trends of the works by analyzing the death accidents cases from 2004 to 2013 and to present the management methods about future hazardous and dangerous works. The results showed that amount of 1,972 cases among 11,513 death accidents were equivalent to the works presented by "Regulation for the hazardous and dangerous work employment restriction". The amount of death accidents in 'Work of using construction equipment following construction machinery management act' was biggest among the death accidents cases and that of 'Work of handling pressure vessels following high-pressure gas safety control act' didn't show up. For the works in "Special education for safety and health"amount of 1,650 death accidents cases were equivalent. The amount of death accidents in 'Work involving a crane with a capacity of 1 ton or more or work which is carried out with a crane or hoist with a capacity of less than 1 ton in a workplace having at least 5 such machines' presented by "Special education for safety and health"was biggest. Also, death accidents case didn't occurred in three works presented by "Special education for safety and health". It was analyzed that works with low death accidents cases should be needed to study thoroughly the whole disaster research involving nonfatal accidents. Through this study, it was expected that regulation can be operated practically in the industrial field. Also, it is considered to increase