• 대한기계학회논문집A
• /
• 제21권3호
• /
• pp.519-527
• /
• 1997

AISI 316 steel has been used extensively for heater and boiler tube of the structural plants such as power, chemical and petroleum plants under severe operating conditions. Usually, material degradation due to microcrack or precipitation of carbides and segregation of impurity elements, is occured by damage accumulated for long-term service at high temperature in this material. In this study, the effect of aging time on fracture toughness was investigated to evaluate the measurement of material degradation. The elastic-plastic fracture toughness behaviour of AISI 316 steel pipe aged at $550^{\circ}C$for 1h-10000h (the aged material) was characterized using the single specimen J-R curve technique and eletric potential drop method at normal loading rate(load-line displacement speed of 0.2mm/min) in room temperature and air environment. The fracture toughness data from above experiments is compared with the $J_{in}$ obtained from predicted values of crack initiation point using potential drop method.

• 한국정보과학회:학술대회논문집
• /
• 한국정보과학회 2007년도 가을 학술발표논문집 Vol.34 No.2 (B)
• /
• pp.17-21
• /
• 2007

Drug discovery is a long process with a low rate of successful new therapeutic discovery regardless of the advances in information technologies. Identification of candidate proteins is an essential step for the drug discovery and it usually requires considerable time and efforts in the drug discovery. The drug discovery is not a logical, but a fortuitous process. Nevertheless, considerable amount of information on drugs are accumulated in UniProt, NCBI, or DrugBank. As a result, it has become possible to try to devise new computational methods classifying drug target candidates extracting the common features of known drug target proteins. In this paper, we devise a method for drug target protein classification by using weighted feature summation and Support Vector Machine. According to our evaluation, the method is revealed to show moderate accuracy $85{\sim}90%$. This indicates that if the devised method is used appropriately, it can contribute in reducing the time and cost of the drug discovery process, particularly in identifying new drug target proteins.

• The Korean Journal of Ecology
• /
• 제4권1_2호
• /
• pp.38-51
• /
• 1981

The present investigation was estimated the effect of temperature, precipitatiion, and time on the decomposition of litters with litter bags of Pinus densiffora and Quercus mongolica at Gure where elevation in 50m, and at Nogodan where elevation in 1300m on Mt. Jiri. As the above results, decomposition model was proposed to relation of the environmental conditions. And was investigated the production and decomposition of litters from the stands of various forest communities in Kwangneung, Mt. Jiri and Mt. Halla. The results are as follows; The models for the decay of organic carbon (C) was as follows: $C=Coe^{-Kt}$ (limiting factor;time) $C=Coe^{-K'te}$ (limiting factor;tempedrature) $C=Coe^{-KnP}$ (limiting factor:precipitation) As observed in litter bag method, the decomposition rate of litter in Pinus densiflora was slower than that of Quercus mongolica. The higher elevation, the slower decomposition rate. The decomposition of litters at Gure where elevation in 50m was equally influenced by temperature and precipitation. But at Nogodan where elevation in 1300m was much inflenced by precipitation. The decay constant of litters was larger in hardwood forest than in coniferous forest. In the same species, the more elevatiion, the less decomposition constant. The time required for the decay of 50%, 95^, 99% of the accumulated litters in the forest floor were faster in hardwood forest than in coniferous forest. In the same species, the higher elevatiion, the longer time required.

• Clinical and Experimental Reproductive Medicine
• /
• 제47권2호
• /
• pp.94-100
• /
• 2020

The inverse correlation between maternal age and pregnancy rate represents a major challenge for reproductive endocrinology. The high embryo ploidy error rate in failed in vitro fertilization (IVF) cycles reflects genetic misfires accumulated by older oocytes over time. Despite the application of different follicular recruitment protocols during IVF, gonadotropin modifications are generally futile in addressing such damage. Even when additional oocytes are retrieved, quality is frequently poor. Older oocytes with serious cytoplasmic and/or chromosomal errors are often harvested from poorly perfused follicles, and ovarian vascularity and follicular oxygenation impact embryonic chromosomal competency. Because stimulation regimens exert their effects briefly and immediately before ovulation, gonadotropins alone are an ineffective antidote to long-term hypoxic pathology. In contrast, the tissue repair properties (and particularly the angiogenic effects) of platelet-rich plasma (PRP) are well known, with applications in other clinical contexts. Injection of conventional PRP and/or its components (e.g., isolated platelet-derived growth factors as a cell-free substrate) into ovarian tissue prior to IVF has been reported to improve reproductive outcomes. Any derivative neovascularity may modulate oocyte competence by increasing cellular oxygenation and/or lowering concentrations of intraovarian reactive oxygen species. We propose a mechanism to support intrastromal angiogenesis, improved follicular perfusion, and, crucially, embryo ploidy rescue. This last effect may be explained by mRNA upregulation coordinated by PRP-associated molecular signaling, as in other tissue systems. Additionally, we outline an intraovarian injection technique for platelet-derived growth factors and present this method to help minimize reliance on donor oocytes and conventional hormone replacement therapy.

• 산업경영시스템학회지
• /
• 제22권51호
• /
• pp.199-210
• /
• 1999

The number of car accident is Recently on the increase in Korea because of the explosive increase of cars, the poor road condition, the lack of safety facility, and others. The insurant with a accident has to decide whether receiving a insurance or not. In this paper, we represent a reasonable decision support material by calculating the approximate insurance fee based on the discount rate and premium additive rate, which is changed by the accident type and the accident expenditure. Practically, there is difference in the standard insurance rate and premium additive rate according to the accident type and the accident expenditure in Korea. The premium additive rate is assessed considering the number of accident, the pattern of accident, and the reason of accident for 3 years. In this paper, we represent a decision making method considering not only the first-time car accident but also the future car accident. For considering the repeated accident, we analyzed the real data accumulated until the year of 1996 from S Insurance Company, and estimated the probability density function between the first and the second-time accident, and executed the goodness of fit test using ARENA and STATISTICA software. Using this conditional PDF, we can calculate the insurance fee next 3 years and compare the insurance fee with the equivalent present value of cash flows. The program performing this analysis is represented, and written in VISUAL BASIC Language. We tried to suggest an accurate guideline for the insurant to decide the insurance coverage rationally, and tried to correct a wrong idea of dependence on the car insurance only by the amount of the accident expenditure. And we expect this study can generally be applied to many different accident types under the uncertain circumstances in our daily life.

• 대한화학회지
• /
• 제45권4호
• /
• pp.298-303
• /
• 2001

생체시료에 함유된 미량수은을 유리질 탄소전극을 사용하는 양극 벗김 네모파 전압-전류법으로 정량하였다. 생체시료는 HNO3/H2SO4 산혼합용액으로 삭히고, KMnO4를 가하여 산화시켰다. 수은의 검출한계는 석출전위, 시 간, pH, 그리고 용액을 저어주는 속도 등에 크게 영향을 받았다. 1.0 volts vs. Ag/AgCl에서 400rpm으로 저어주면서 240 sec 동안 석출시켰을 경우, 검출한계는 0.5 ppb 이하였다. 흰쥐에 대한 수은의 생체 축적량은 신장과 간에서 높았고, 뇌에서는 매우 낮았다.

• 공업화학
• /
• 제28권1호
• /
• pp.118-124
• /
• 2017

공랭식 고분자전해질 연료전지는 개방된 cathode구조로 인하여 시스템의 단순화와 부품 수 저감의 장점이 있다. 공랭식 연료전지는 최근에 많이 연구되고 있지만, 성능이 외부 환경에 영향을 받으며, 공기의 상대습도가 낮은 경우 전해질막의 건조로 인한 성능 감소가 발생할 수 있다. 본 연구에서는 공랭식 연료전지의 성능에 영향을 주는 요인인 cathode 측 공기 유량과 anode 측 purge interval영향에 대해 분석하였으며, 스택을 운전하지 않는 상태로 장기간 보관하는 것이 성능에 미치는 영향에 대하여 실험을 수행하였다. 연료전지 외부에 설치한 fan의 전압을 조절하면 cathode 측 공기의 공급유량을 변화시킬 수 있고 스택의 온도도 제어할 수 있으므로, fan전압은 공랭식 연료전지의 성능에 영향을 주는 중요한 인자이다. 연료전지 시스템을 단순화하고 수소의 사용률을 높이기 위하여 anode 측은 dead ended anode (DEA) 기법을 사용하였다. 주기적인 purge를 실행하여 생성된 물과 가스를 배출하였으며, purge 주기를 변경하면서 스택의 성능에 미치는 영향에 대하여 실험을 수행하였다. 스택의 보관기간이 길어질수록 membrane dehydration으로 인해 성능이 감소하는 것을 실험을 통해 파악하였고, 단시간에 성능을 회복할 수 있는 기법을 제시하였다.

• 한국물환경학회지
• /
• 제39권5호
• /
• pp.377-389
• /
• 2023

Chungcheongnam-do has been measuring the flow rate and water quality of streams in the province once a month since 2011 in order to water environment policies. Based on the results, after evaluating the coefficient of variation and the tendency of the water quality trend by using the Mann-Kendall test and Sen's Slope for each stream, the streams subject to priority introduction of Total Pollution Load Management at Tributaries were selected through the Stream Grouping Method. The water quality trend analysis results for 125 streams using the Mann-Kendall test and Sen's Slope were evaluated as streams showing a tendency of deteriorating water quality Biochemical oxygen demand (BOD): 13 streams, Total Phosphorus (T-P): 16 streams). Streams with deteriorating water quality were classified into A-D groups using the Stream Grouping Method. Group A, which has a high flow rate and high water quality, is a stream that requires priority management, and was selected as a stream for introduction of Total Pollution Load Management at Tributaries. There are 7 streams that need to be introduced into the BOD category, and there are 7 streams that need to be introduced into the T-P category. In this study, based on flow and water quality monitoring data accumulated over a long period of time (2011-2022), statistical techniques are used to select watersheds in which water quality is deteriorating. Accordingly, it is expected that it will be useful in establishing a water quality improvement plan in the future.

• Radiation Oncology Journal
• /
• 제17권3호
• /
• pp.179-187
• /
• 1999

치료선량의 증가와 주위 정상조직의 보호의 의미에서 근접치료의 효과는 입증되어 있다. 그러나 우리 나라에서는 아직 통상치료법으로 상용화가 되어 있지 않다. 저자는 저선량률 이리디움 근접조사치료의 임상적 경험을 바탕으로 두경부암에서의 근접조사치료의 역사, 사용되는 동위원소의 재원 및 특성, 시행 시 고려 하여야할 사항, 임상기술적인 문제, 방사선물리학적 문제 등을 검토하였고 저자의 임상 경험 185례의 치료성적을 분석하여 그 효과를 검증하였고 마지막으로 향후 발전방향을 제시하여 보았다.

• Journal of the Korean Data and Information Science Society
• /
• 제28권2호
• /
• pp.361-369
• /
• 2017

본 논문은 국제원유가격에 대한 환율의 인과관계를 분석하였다. 두 변수의 인과관계에 대해서는 많은 선행연구들이 있지만 인과관계의 유무에 대해서는 결과들이 일치하지 않고 있다. 본 연구는 이러한 상반된 결과들이 경제상황에 따라 각기 다른 인과관계가 분석되었을 가능성에 착안해서 분위수별로 인과관계를 분석하며 이 점에서 지금까지 평균 인과관계를 분석한 선행연구들과 차별화된다. 자료는 Brent 원유의 국제가격과 미국의 주요국 환율의 가중평균 (major currencies dollar index; MCDI)의 1987년 5월부터 2013년 7월까지 기간의 월별자료를 이용하였다. 분석방법으로서 분위수 인과관계 개념에 대해 비모수 커널방법을 적용한 Jeong 등 (2012) 방법을 사용하였다. 분석결과, 전통적인 평균 인과관계에서는 달러 환율이 원인이고 Brent 원유가격이 결과인 인과관계가 존재하는 반면에, 비모수분위수검정에서는 중앙값인 0.5 분위수 근방의 분위수에서는 인과관계가 존재하고 대부분 분위수에서 인과관계는 존재하지 않는 것으로 나타나서 평균인과 검정결과를 해석할 때 주의가 필요한 것으로 나타났다.