• Title/Summary/Keyword: Accelerated life data

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A Comparative Study of Subset Construction Methods in OSEM Algorithms using Simulated Projection Data of Compton Camera (모사된 컴프턴 카메라 투사데이터의 재구성을 위한 OSEM 알고리즘의 부분집합 구성법 비교 연구)

  • Kim, Soo-Mee;Lee, Jae-Sung;Lee, Mi-No;Lee, Ju-Hahn;Kim, Joong-Hyun;Kim, Chan-Hyeong;Lee, Chun-Sik;Lee, Dong-Soo;Lee, Soo-Jin
    • Nuclear Medicine and Molecular Imaging
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    • v.41 no.3
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    • pp.234-240
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    • 2007
  • Purpose: In this study we propose a block-iterative method for reconstructing Compton scattered data. This study shows that the well-known expectation maximization (EM) approach along with its accelerated version based on the ordered subsets principle can be applied to the problem of image reconstruction for Compton camera. This study also compares several methods of constructing subsets for optimal performance of our algorithms. Materials and Methods: Three reconstruction algorithms were implemented; simple backprojection (SBP), EM, and ordered subset EM (OSEM). For OSEM, the projection data were grouped into subsets in a predefined order. Three different schemes for choosing nonoverlapping subsets were considered; scatter angle-based subsets, detector position-based subsets, and both scatter angle- and detector position-based subsets. EM and OSEM with 16 subsets were performed with 64 and 4 iterations, respectively. The performance of each algorithm was evaluated in terms of computation time and normalized mean-squared error. Results: Both EM and OSEM clearly outperformed SBP in all aspects of accuracy. The OSEM with 16 subsets and 4 iterations, which is equivalent to the standard EM with 64 iterations, was approximately 14 times faster in computation time than the standard EM. In OSEM, all of the three schemes for choosing subsets yielded similar results in computation time as well as normalized mean-squared error. Conclusion: Our results show that the OSEM algorithm, which have proven useful in emission tomography, can also be applied to the problem of image reconstruction for Compton camera. With properly chosen subset construction methods and moderate numbers of subsets, our OSEM algorithm significantly improves the computational efficiency while keeping the original quality of the standard EM reconstruction. The OSEM algorithm with scatter angle- and detector position-based subsets is most available.

Research and Application of Ergonomics in the Portable Flashlight Design (인간공학을 적용한 손전등 디자인 연구)

  • Hao, Qian;Kang, Bum-Kyu;Kim, Sung-Hyun
    • The Journal of the Korea Contents Association
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    • v.13 no.10
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    • pp.256-265
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    • 2013
  • With economic development and ever-changing technology, human has entered the era of "Product-as-a-Service". At the same time, the update of the product gradually accelerated. The demand of consumers for products are slowly changed, they pay more attention to convenience, comfort and reliable quality and safety of the product. That is the humanized design problem that often mentioned in the product design. This also put forward new requirements for the design and development of product modeling. So how to reflect the humanized ideas in the product design has also become common focus of attention of product designers, users and producers of a new era. The paper is based on the principles of ergonomics to investigate and improve the daily life utensil - flashlight. Firstly, make a sample survey of the flashlight in Beijing market and analyze the characteristics and problems of flashlight products. Secondly, explore the use of the flashlight and proposed Flashlight curved grip design to reduce the occurrence of wrist discomfort and damage to the body caused by poor posture of the operation of users. Finally, determine the range of the length and width of the body of the flashlight according to the length and width measurement data of the Chinese palm. Wishing that the improvements of flashlight products in ergonomics can improve use of feelings of these products and give a theoretical guidance for solving similar problems.

NecroX-5 exerts anti-inflammatory and anti-fibrotic effects via modulation of the TNFα/Dcn/TGFβ1/Smad2 pathway in hypoxia/reoxygenation-treated rat hearts

  • Thu, Vu Thi;Kim, Hyoung Kyu;Long, Le Thanh;Thuy, To Thanh;Huy, Nguyen Quang;Kim, Soon Ha;Kim, Nari;Ko, Kyung Soo;Rhee, Byoung Doo;Han, Jin
    • The Korean Journal of Physiology and Pharmacology
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    • v.20 no.3
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    • pp.305-314
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    • 2016
  • Inflammatory and fibrotic responses are accelerated during the reperfusion period, and excessive fibrosis and inflammation contribute to cardiac malfunction. NecroX compounds have been shown to protect the liver and heart from ischemia-reperfusion injury. The aim of this study was to further define the role and mechanism of action of NecroX-5 in regulating inflammation and fibrosis responses in a model of hypoxia/reoxygenation (HR). We utilized HR-treated rat hearts and lipopolysaccharide (LPS)-treated H9C2 culture cells in the presence or absence of NecroX-5 ($10{\mu}mol/L$) treatment as experimental models. Addition of NecroX-5 significantly increased decorin (Dcn) expression levels in HR-treated hearts. In contrast, expression of transforming growth factor beta 1 ($TGF{\beta}1$) and Smad2 phosphorylation (pSmad2) was strongly attenuated in NecroX-5-treated hearts. In addition, significantly increased production of tumor necrosis factor alpha ($TNF{\alpha}$), $TGF{\beta}1$, and pSmad2, and markedly decreased Dcn expression levels, were observed in LPS-stimulated H9C2 cells. Interestingly, NecroX-5 supplementation effectively attenuated the increased expression levels of $TNF{\alpha}$, $TGF{\beta}1$, and pSmad2, as well as the decreased expression of Dcn. Thus, our data demonstrate potential antiinflammatory and anti-fibrotic effects of NecroX-5 against cardiac HR injuries via modulation of the $TNF{\alpha}/Dcn/TGF{\beta}1/Smad2$ pathway.

Characteristics Measurement of Hyperelastic SMA Gear for Micro-jitter Attenuation of X-band Antenna of Compact Advanced Satellite (차세대중형위성 적용가능성 검토를 위한 X-band 안테나의 미소진동 저감용 초탄성 SMA 기어의 특성 측정)

  • Jeon, Young-Hyeon;Back, Hyeon-Gyu;Song, Da-Il;Kang, Eun-Su;Oh, Hyun-Ung
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.45 no.9
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    • pp.784-793
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    • 2017
  • A two-axis gimbal-type X-band antenna mounted on an observation satellite can efficiently transmit high-capacity image data to a ground station regardless of both the satellite position and the orbital motion. However, this X-band antenna induces unnecessary micro-jitter which can degrade the image quality of the high-resolution observation satellite. Therefore, to achieve the high-resolution image quality from the observation satellite, micro-jitters have been required to be isolated. In this study, to resolve aforementioned drawback, we proposed blade gear using a shape memory alloy (SMA) applied to azimuth stage of X-band antenna. To investigate the rotational basic characteristics of the proposed SMA blade gear, we performed rotational static loading test. Futhermore, to evaluate the cycle to failure of the gear, accelerated life test was conducted. The temperature test was conducted to confirm rotational basic characteristics at various temperature conditions. To verify the isolation performance for micro-jitter, we performed micro-jitter measurement test.

The Prediction Model of Carbonation Process by CO2 Diffusion Using the Air Permeability Coefficient for Concrete (콘크리트의 투기계수를 이용한 CO2확산 탄산화진행 예측모델)

  • Kang, Suk-Pyo;Kim, Young-Sun;Song, Ha-Won;Kim, Gyu-Yong
    • Journal of the Korea Concrete Institute
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    • v.22 no.2
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    • pp.209-217
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    • 2010
  • Recently, some mathematical models for the prediction on progress of carbonation of concrete were reported. These models take account for $CO_2$ diffusion and chemical reaction between $Ca(OH)_2$ and $CO_2$. Based on the assumption that $CO_2$ diffuses in the carbonation zone and reacts with $Ca(OH)_2$ at the outer face of carbonation zone and non-carbonation zone. In this study, a mathematical model to predict the progress of carbonation of concrete has been established based on the reducing concentration of $Ca(OH)_2$ in the carbonation progress zone, where $Ca(OH)_2$ reacts with $CO_2$ and $Ca(OH)_2$ and $CaCO_3$ coexist. Also, the prediction model of carbonation progress rate of concrete using the air permeability coefficient regarding to $CO_2$ diffusion is developed. As a result of this study, an expression, the model equation is obtained for the prediction of carbonation based on the time and interaction velocity between $CO_2$ and Ca(OH)$_2$ dependent air permeability coefficient. The prediction by the model satisfied the experimental data of the accelerated carbonation for painted concrete. Consequently, the model can predict the rate of carbonation and the potential service life of concrete structure exposed to atmosphere.

Analysis on the Relationships among the Total Cholesterol, Fasting Blood Sugar, Hypertension and Ischemic Heart Disease on EKG Findings (혈청 총콜레스테롤, 공복시 혈당, 혈압의 분포와 심전도상 허혈성 심질환과의 관련성)

  • Kim, Soo-Keun;Roh, Sang-Chul;Son, Jung-Il;Choi, Bo-Youl
    • Journal of Preventive Medicine and Public Health
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    • v.29 no.4 s.55
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    • pp.705-719
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    • 1996
  • Since the 1960s, Korea has achieved rapid economic growth, longer life expectancy, accelerated urbanization and a westenization of diet. Cardiovascular disease has become the leading cause of death; however the prevalence of ischemic heart disease(IHD) remains low. A cross-sectional multiphasic screening service for 18,426 persons aged $30\sim64$ years in a Medical Aid Program in Kyonggi-do Province was conducted from 1991 to 1993. Total cholesterol(TC), fasting blood glucose(FBG), blood pressure(BP), and electrocardiographic(EKG) data were collected. The result as follows ; 1. On the EKG findings, the age-adjusted prevalence of myocardial ischemia and myocardial infarction was 1.45% in men and 2.06% in women. 2. The mean blood pressure was 122.9/78.8mmHg. The age-adjusted prevalence of hypertension was 11.05% in men and 9.02% in women. The prevalence of hypertension showed increasing tendency according to age increase. In all age group, the prevalence of hypertension was higher in men than women. 3. The mean total cholesterol level was 184.4mg/dl in men and 189.2mg/dl in women. The age-adjusted prevalence of hypercholesterolemia was 4.88% in men and 5.67% in women. The total cholesterol level showed increasing tendency according to age increase, except $55\sim64$ age group in men. 4. The prevalence of hyperglycemia is 5.8%. The age-adjusted prevalence of hyperglycemia is 6.72% in men and 4.50% in women. The prevalence of hyperglycemia showed increasing tendency according to age increase. 5. On the EKG findings, the prevalence of myocardial ischemia and myocardial infarction was higher in hypertension than normal, in all age group of men and women less than 40 years-old. Only in women more t]fan 40 years-old, the prevalence of myocardial ischemia and myocardial infarction was higher in hypercholesterolemia and hyperglycemia. Nevertheless there is not statistical association between ischemia heart disease and previous risk factors in other age group, the prevalence of myocardial ischemia and myocardial infarction was higher in hypertension, hypercholesterolemia and hyperglycemia than normal. The result of this study suggest that relationships between major risk factor of ischemic heart disease and ischemic heart disease is similar to existing theory.

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Damage-Spread Analysis of Heterogeneous Damage with Crack Degradation Model of Deck in RC Slab Bridges (RC 슬래브교의 바닥판 균열 열화모델에 따른 이종손상 확산 분석)

  • Jung, Hyun-Jin;An, Hyo-Joon;Kim, Jae-Hwan;Part, Ki-Tae;Lee, Jong-Han
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.26 no.6
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    • pp.93-101
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    • 2022
  • RC Slab bridges in Korea account for more than 70% of the total bridges for more than 20 years of service. As the number of aging structures increases, the importance of safety diagnosis and maintenance of structures increases. For highway bridges, cracks are a main cause of deck deterioration, which is very closely related to the decrease in bridge durability and service life. In addition, the damage rate of expansion joints and bearings accounts for approximately 73% higher than that of major members. Therefore, this study defined damage scenarios combined with devices damages and deck deterioration. The stress distribution and maximum stress on the deck were then evaluated using design vehicle load and daily temperature gradient for single and combined damage scenarios. Furthermore, this study performed damage-spread analysis and predicted condition ratings according to a deck deterioration model generated from the inspection and diagnosis history data of cracks. The heterogeneous damages combined with the member damages of expansion joints and bearings increased the rate of crack area and damage spread, which accelerated the time to reach the condition rating of C. Therefore, damage to bridge members requires proper and prompt repair and replacement, and otherwise it can cause the damage to bridge deck and the spread of the damage.

The Stakeholder's Response and Future of Mountain Community Development Program in Rep. of Korea (한국 산촌개발사업에 대한 이해관계자의 의식과 향후 발전방안)

  • Yoo, Byoung Il;Kim, So Heui;Seo, Jeong-Weon
    • Journal of Korean Society of Forest Science
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    • v.94 no.4 s.161
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    • pp.214-225
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    • 2005
  • The mountain village development program in Korea started in the mountain villages, the 45.9% of total land and one of the typical marginal region, from 1995 to achieve the equilibrium development of national land and the sustainable mountain development in Chapter 13 in Agenda 21, and it has been accelerated to increase the happiness and the quality of life of mountain community residents through the expansion by province and the improvement of related laws and regulations. This study has been aimed to analyze the response of main stakeholder's -mountain village residents and local government officials - on mountain villages development, and to provide the future plan as community development. The survey and interview data were collected from the mountain villages which already developed 59 villages and developing 15 villages in 2003. The mountain village development program has achieved the positive aspects as community development plan in the several fields, - the voluntary participation of residents, the establishment of self-support spirit as the democratic civilians, the development of base of income increasement, the creation of comfortable living environment, the equilibrium development with the other regions. Especially the mountain residents and local government officials both highly satisfy with the development of base of income increasement and the creation of comfortable living environment which are the main concerns to both stakeholder. However through the mountain development program, it is not satisfied to increase the maintenance of local community and the strengthening of traditional value of mountain villages. Also to improve the sustainable income improvement effects, it is necessary to develop the income items and technical extension which good for the each region. In the decentralization era, it is necessary for local government should have the more active and multilateral activities for these. With this, the introduction of methods which the mountain community people and the local government officials could co-participate in the mountain villages' development from the initial stages and the renovation of related local government organizations and the cooperatives will be much helpful to the substantiality of mountain development program. Also it is essential for the assistance of central government to establish the complex plan and the mountain villages network for all mountain area and the exchange of information, the education and training of mountain villages leader who are the core factor for the developed mountain villages maintenance, the composition of national mountain villages representatives. In case the development proposals which based on the interests of the main stakeholder's on mountain community could be positively accepted, then the possibility of the mountain village development as one of community development will be successfully improved in future.