• Nuclear Engineering and Technology
• /
• v.55 no.2
• /
• pp.669-673
• /
• 2023

Introduction: The crucial step in preclinical process of radiopharmaceutical production is internal dosimetry evaluation by different ways to realize radiobiological dose-response relationships and to extract the results for clinical use. Till now several bone-seeking radiopharmaceuticals have been developed for bone metastasis. Interesting features of bisphosphonates attracted attentions to them in the field of radiopharmaceutical therapy and studies on new generation of them have been doing too. Materials and methods: In this study, we used ZNA as representative of the third generation. The radiopharmaceutical ¹⁸⁸Re-ZNA was produced and its radiochemical purity was investigated. Then, the biological distribution of the produced radiopharmaceutical at 1, 2, 4 and 24 h after injection on different organs of mice were investigated. Finally, the absorbed dose of organs in the human body was assessed using the RADAR method. Results: The results show 96% radiochemical purity of the ¹⁸⁸Re-ZNA radiopharmaceutical. The amount of %ID/g in bone is 1.131% after 1 h and in 24 h it has a significant amount compared to other organs, that is 0.516%. Also dosimetric results show that the highest absorption dose is related to bone and the amount of this dose is 0.050 mGy/MBq. Conclusion: Considering the possibility of producing the ¹⁸⁸Re-ZNA radiopharmaceutical, as well as the proper distribution of this radiopharmaceutical in target and non-target organs and increasing the absorbed dose in bone, it can be concluded that this radiopharmaceutical can be useful in the "radiopharmaceutical therapy" in metastases.

• Journal of the Korea institute for structural maintenance and inspection
• /
• v.25 no.5
• /
• pp.68-75
• /
• 2021

This study performed simulating water absorption in various pre-cracked concretes. 2D-Finite Element Analysis (2D-FEA) model was developed based on experimental results on the amount of absorbed water in concrete with the exposure time. Results from the 2D-FEA showed that both crack width and crack depth strongly affect the amount of absorbed water in cracked concrete. In addition, water absorption rate is introduced and a predictive equation is suggested to estimate the rate in order to quantify the amount of absorbed water in cracked concrete. It was confirmed that water absorption in concrete having less than 150 mm crack depth was dominated as a main transport factor regardless of crack width. Therefore, considering that steel corrosion caused by chlorides dissolved in water mainly occurs in reinforced concrete structures, it is necessary that crack depth as well as crack width should be investigated in reinforced concrete structures at the time of field-inspection.

• Korean Journal of Soil Science and Fertilizer
• /
• v.10 no.4
• /
• pp.245-256
• /
• 1978

The effects of different particle size distribution of fused phosphate on the changes of phosphorus content in soil and plant, growth and yield of paddy rice were investigated through pot and field experiments. The following results were obtained. 1. Negative correlation was found between unhulled rice yield and the composition of fused phosphate whose particle size was larger than 28 mesh, and 65 to 150 mesh, and highly significant correlation was found between unhulled rice yield and the composition of fused phosphate whose particle size was 28 to 48 mesh. But no significant correlation was found betweeen unhulled rice yield and the composition of fused phosphate whose particle size was 48 to 65 mesh. Thus the composition of 56% of 28 to 48 mesh particles and 44% of 48 to 65 mesh particles would give the best effect. 2. In the soil of the Jeonbug series rice plant in the plots treated with fine single textured fused phosphate showed poor early growth, i.e. poor tillering and short plant height. But at harvesting stage it showed rather increased number of tillers and higher plant height. Of the composite fused phosphate the more particles of 28 to 48 mesh it had, the better growth it showed. In the soil of the Yesan series rice plant in the treated plots showed much better tillering and higher plant height in contrast with that in the control plots. Of the single textured fused phosphate the finer particles showed better growth, while of the composite fused phosphate the more particles finer than 48 mesh it had, the poorer the tillering. 3. The content of available phosphorus in the soil tended to increase as the particles of both single textured and composite phosphate became finer. The soil phosphorus content decreased as the content of phosphorus absorbed by rice plant increased at each stage of growth, and the amount of soil phophorus decreased became larger as the the particles were finer. The amount of available phosphorus in the treated soils was larger in the soil of the Yesan series than in the soil of the Jeonbug series which was a long cultivated soil and contained relatively high phosphorus. 4. In the single textured fused phosphate the amount of phosphorus absorbed by rice plant tended to increase as the particles were finer, and great difference was found at heading stage, but at harvesting stage little difference was found for all the plots. In the field experiment in the soil of the Jeonbug series more phosphorus was absorbed by rice plant in the plots treated with the composite fused phosphate of higher content of 28 to 48 mesh particles. In the pot experiment the amount of phosphorus absorbed by rice plant was highest in the plots treated with the composite fused phosphate of 53.35% of particles larger than 48 mesh and 46.6% of particles smaller than 48 mesh. In the pot experiment in the Yesan series the amount of absorbed phophorus was highest in the plots treated with the fused phosphate of 47.75% of particles larger than 48 mesh and 50. 216% of particles smaller than 48 mesh. 5. A reverse relationship was found between the absorbed phosphorus and silica. In the pot experiment in the soils of both the Jeonbug and Yesan series the amount of phosphorus absorbed by rice plant increased as the particles were finer, while the amount of absorbed silica tended to decrease.

• The Journal of the Korea Contents Association
• /
• v.18 no.1
• /
• pp.232-240
• /
• 2018

This study is to suggest a method to evaluate the detector performance using change of absorbed dose and histogram according to sensitivity change of Auto Exposure Control(AEC). The experiment site is skull, abdomen pelvis and the accuracy of the detector was evaluated by measuring the absorbed dose of the detector sensitivity S200, S400, S800, S1000. Also the dynamic range of the detector was evaluated through the histogram analysis. As a result, the absorbed dose decreased gradually as the sensitivity was set higher from S200 to S1000. And through the sensitivity histogram analysis, as the sensitivity of the skull is set higher, the amount of information at both ends of the histogram is lost. Abdomen and pelvis areas showed underflow phenomena in which the amount of information in the first part of the histogram was lost as the sensitivity was set higher. In conclusion, the detector accurately implemented the sensitivity change, but the dynamic range of the image due to the sensitivity change of the AEC due to the deterioration of the detector performance can not be realized properly and it was found that the evaluation through the absorbed dose and the histogram is useful when evaluating the performance of the detector.

• Journal of the Korean Society of Clothing and Textiles
• /
• v.21 no.5
• /
• pp.903-910
• /
• 1997

Vit. D3 was measured which was produced by UVB irradiation to provit. D3, 7-d ehyd rock o 1 cst or of (7-DH Cl Measuring the amount of vie. D3 when it was irradiated to the fabrics which had different UV8 transmittance, production of vile. Ds by UVB(Ultraviolet B) and inhibition from formation of vile. D3 by fabrics were absorbed and followings are the results. As the amount of irradiated compared UVB increased, the amount of the production of vile. D3 produced by UVB irradiation from 7-DHC was increased. After treatment of 7-DHC by UVB irradiation and incubated respectively for 24hr, 48hr and 72hr at 36.5$^{\circ}C$ The amount of lit. D3 was increased as incubating time passed. When irradiated UVB on 7-DHC, intermediate of vile. D3, lumisterol, tachysterol and previt. D were showed and those materials were seemed to be changed to vile. D3 as incubation time passed. The amount of vile. D3 which was produced by irradiation 7-DHC showed close relation with UVB transmittance rate of summer fabrics (r= 0.987). Clothes, hats, and sun screen cream reduce the amount of vile. D3 Produced naturally in human skin and it result the decrease of calcium in blood which is absorbed through vit. D. Those all can cause or worsen osteomalacia especially to women and the aged people. Therefore, it is necessary to research and to develop function oriented clothing which can transmit UV which produce vile. D3 at the same time which can protect toxical UVB.

• Journal of Bio-Environment Control
• /
• v.10 no.3
• /
• pp.133-140
• /
• 2001

This study was conducted to develop a nutrient uptake model in cucumnber (Cucumis sativus L. cv. Eunsung Backdadagi) plants for prediction of the amount of nutrients in drainage solution in a closed perlite culture system. Electrical conductivity (EC) of the nutrient solution was adjusted to 1.5, 1.8, 2.1, 2.4, and 2.7 dS. $m^{-1}$ . The amount of nutrient solution absorbed in different EC treatments was not different until the mid stage of growth. However, after the mid growth stage, a high EC treatment resulted in less solution absorption. The absorption rates of K, N $O_3$$^{[-10]}$ -N, Mg, and P increased continuously for a whole growing period in all treatments, while those of Ca decreased slightly. For S, the decrease was significant after th mid stage of growth. although the amounts of absorbed inorganic ions in different EC treatments were not significantly different at the first stage of growth, they were significantly different after the mid stage of growth and decreased slightly at the end of growth stage. Models for predicting the amounts of each inorganic ion absorbed were developed by using EC and the amount of nutrient solution absorbed per unit radiation(mg.M $J^{-1}$), which proved to be practical with a positive correlation at 1 percent probability between the developed model and practical values..

• Korean Journal of Soil Science and Fertilizer
• /
• v.34 no.5
• /
• pp.358-364
• /
• 2001

To obtain information for the proper fertilization management of cut-flower roses, the amount of macro and micro elements absorbed by cut-flower roses from soil for a year was investigated. Three cut-flower rose cultivars which are called 'Grandgara', 'Nobless', and 'Centina' were transplanted to a sandy loam soil, N-P-K standard fertilization was applied to the soil, and drip irrigation was done at the level of 10 kPa soil moisture tension. There was not significantly different in the harvest amount of cut-flower rose between 'Grandgara' and 'Nobless', but the harvest yield of 'Centina' was about 63% level when compared to that of 'Grandgara'. Considering seasonal changes in the content of nutrients in plant, parts, the uptake of untrients was higher in winter season than that in spring and summer seasons. Except for 'Centina', the nutrient amount removed from plant parts of 'Grandgara' and 'Nobless' increased with the sequence of floral part < stem < leaf, indicating that it is more dependent on biomass yield than on the content of nutrients in each plant part. The ratio of N/K amount absorbed by 'Nobless' and 'Centina' was 1.13 and 1.28. respectively, lower than 1.68 of 'Grandgara', showing that the requirement for K is greater in 'Nobless' and 'Centina' than in 'Grandgara'. The use efficiency of nutrients by cut-flower roses ranged from 39 to 64% in nitrogen, 5 to 9% in phosphorus, and 37 to 67% in potassium. It suggests that the requirement for P in cut-flower roses is very low.

• Korean Journal of Soil Science and Fertilizer
• /
• v.17 no.1
• /
• pp.39-45
• /
• 1984

The effects of foliar application of phosphate was investigated in the light of plant physiological point of view. The phosphate applied on the foliar both in meiosis and heading time was penetrated considerably into the rice. The amount of P absorbed by foliar application at high temperature was higher than that at low temperature but still considerable amount of P was absorbed at low temperature. The phosphate applied on younger flag leaf was absorbed more vigorously than the second and third leaves. The absorbed P on leaf was translocated to the panicle, especially on the brown rice starch, then moved to another panicle wherever the phosphate was needed. The major fraction of absorbed P under high temperature condition was T.C.A. soluble-Ba insoluble phosphate of mainly phytic form but Ba soluble-EtOH insoluble fraction, sugar phosphate ester, was identified as dominant P under low temperature condition.

• Journal of Nutrition and Health
• /
• v.27 no.8
• /
• pp.828-836
• /
• 1994

A low level exposure experiment was conducted on growing rats to investigate the accumulation and organ distribution of protein bound cadmium compared with cadmium chloride. Male Sprague-Dawley rats were fed for 21days with one of the semisynthetic diets, which contains cadmium as either bovine liver- or kidney meal bound cadmium, cadmium chloride with uncontaminated liver meal or cadmium chloride without organ meal, in the levels of ca. 0.5, 1 and 1.5mg/kg diet, respectively. After 21days of exposure cadmium was accumulated in liver, kidney and gastrointestinal tracts depending upon cadmium levels in diet. Inspite of very low cadmium accumulation in whole blood, it tends also to increase with dietary cadmium levels. The blood cadmium concentration of animals fed organ meal containing diets was about 4-7 fold higher than that without organ meal, regardless of cadmium was intrinsically bound to protein or not. However, significant effects of organ protein on cadmium accumulation in liver, kidney and digestive tracts were not detectable, when cadmium was supplemented as cadmium chloride. On the other hands, animals fed diet containing ca. 1.5mg Cd/kg as organ bound cadmium retained more cadmium in liver, kidney and digestive tracts compared to cadmium chloride with organ meal, whereby the increase of cadmium concentration in kidney was greater then in liver. However, when the concentration of protein bound cadmium was<1mg/kg diet, organ bound cadmium was not significantly different from cadmium chloride in bioavailability and organ distribution. From this result it is suggested that the intestinal absorption of protein bound cadmium is influenced of the amount of cadmium bound in protein. When cadmium concentration in protein is relatively low, protein bound cadmium seems to be absorbed in the same way as cadmium ions are absorbed. However, when the concentration is high, at least a small amount of intact protein bound cadmium could be absorbed and accumulated selectively in kidney.

• The Korean Journal of Ecology
• /
• v.20 no.1
• /
• pp.27-33
• /
• 1997

Species composition and the amount of nutrients absorbed by regenerating plants on a pine forest in the immediate postfire year were compared with those in an unburned pine forest in Kosung, Kangwon Province. Pteridium aquilinum var. latiusculum, Cyperus amuricus, Lespedeza biolor, Quercus serrata, Lysimachia clethroides were the most abundant species in burned area. In unburned area. Quercus mongolica, Rhododendron mucronulatum, Carex humilis, Rhododendron schlippenbachii, Spodiopogon sibiricus were the most abundant species. Standing biomass of understory vegetation in burned and unburned area was 170.2 g $D.W/m^2$ and 171.3g $D.W/m^2$, respectively. Nutrient concentrations of plants in burned area, especially for phosphorus and potassium, were higher than those in unburned area. The amounts of nutrients absorbed by understory plants in burned and unburned area were 37.4 and 33.6 kg/ha for N, 0.36 and 0.19 kg/ha for P, 30.6 and 18.8 kg/ha for K, 8.5 and 7.8 kg/ha Ca, 5.2 and 5.7 kg/ha for Mg, respectively. This suggests that regenerating vegetation can hold the significant amount of nutrients, although there may be considerable losses of nutrients from ecosystem after fire.