• Journal of Korean Academy of Nursing
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• v.29 no.4
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• pp.903-916
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• 1999

The purpose of this study was to compare the ear-based rectal temperature measured with a tympanic thermometer with the rectal temperature measured with a glass mercury thermometer in order to test the accuracy of tympanic thermometer and to determine relationship among rectal, axilla, and abdominal temperature in neonates. The samples consisted of thirty four neonates admitted to the neonatal intensive care unit and nursery at an university affiliated hospital. The mean age of the subjects was 4.9 days. The ear-based rectal temperatures were taken with a tympanic thermometer in rectal mode (First Temp Genius 3000). Rectal and axilla temperatures were taken with a glass mercury thermometer, Abdominal temperature was continuously monitored with the probe connected to the servo controller of incubator. The results of the study can be summarized as follows : 1. Intrarater comparison : Agreement between the first and the second ear-based rectal temperature was 97% within 0.1$^{\circ}C$. 2. Comparison of ear-based rectal temperature and the rectal temperature from a glass mercury thermometer : ear-based rectal temperature ranged from 36.95$^{\circ}C$d to 37.95$^{\circ}C$, with a mean of 37.58$^{\circ}C$(SD＝0.22$^{\circ}C$). Rectal temperature from a glass mercury thermometer ranged from 36.2$0^{\circ}C$ to 37.2$0^{\circ}C$, with a mean 36.75$^{\circ}C$(SD＝0.29). The mean difference between both temperatures was 0.84$^{\circ}C$. The correlation coefficient between both temperatures was r＝0.77(p＝0.00). 3. Comparison of rectal and axilla temperature : Axilla temperature ranged from 35.8$0^{\circ}C$ to 37.1$0^{\circ}C$, with a mean of 36.55$^{\circ}C$. The mean absolute difference between the rectal and axilla temperature was 0.23$^{\circ}C$. The correlation coefficient between rectal and axilla was r＝0.67. 4. Comparison of axilla and abdominal temperature : Abdominal temperature ranged from 36.2$0^{\circ}C$ to 37.0$0^{\circ}C$, with a mean of 36.58$^{\circ}C$. The mean absolute difference between axilla and abdominal temperature was only -0.03$^{\circ}C$. Findings of this study suggest that ear-based rectal temperature overestimates the actual rectal temperatures in neonates. Therefore, the interchangeble use of both temperatures in clinics seems problematic. The site offset(adjustment value) programmed in rectal mode of the tympanic thermometer needs to be readjusted. Choosing one optimal site for temperature measurement for each patient, and using the specific site consistently would result in more consistent measurements of changes in body temperature, and thus can be more effective in diagnosing fever or hypothermia.

• Journal of Sensor Science and Technology
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• v.9 no.2
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• pp.96-105
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• 2000

Fiber optic TR-EFPI(total reflected extrtinsic Fabry-Perot interferometric) sensor was developed to measure the strain of structures, such as building, bridge, aircraft, etc. It has been difficult to distinguish the increase and decrease of the strain from the conventional fiber optic EFPI sensor because their signals only have a sinusoidal wave pattern related to the change of strain. Also, the absolute strain could not be measured by the simple fiber optic EFPI sensor. In this study, in order to measure the magnitude of strain with the direction of strain, the fiber optic sensor was simply constructed with the total reflected EFPI sensor probe. This probe was manufactured with a single mode fiber and a mirror coated fiber in a silica glass capillary tube. The output signal of this fiber optic TR-EFPT sensor can give the information about the magnitude and the direction of strain. The loading-unloading test was performed by the universal testing machine with alluminum beam specimen to compare the strain from fiber optic TR-EFPI sensor with the value from electrical strain gauge. In the result of this experiment. the strain from fiber optic TR-EFPI sensor had a good agreement with the values from the electrical strain gauge.

• Journal of Veterinary Science
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• v.23 no.4
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• pp.56.1-56.17
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• 2022

Background: At the therapeutic doses, diclofenac sodium (DFS) has few toxic side effects on mammals. On the other hand, DFS exhibits potent toxicity against birds and the mechanisms remain ambiguous. Objectives: This paper was designed to probe the toxicity of DFS exposure on the hepatic proteome of broiler chickens. Methods: Twenty 30-day-old broiler chickens were randomized evenly into two groups (n = 10). DFS was administered orally at 10mg/kg body weight in group A, while the chickens in group B were perfused with saline as a control. Histopathological observations, serum biochemical examinations, and quantitative real-time polymerase chain reaction were performed to assess the liver injury induced by DFS. Proteomics analysis of the liver samples was conducted using isobaric tags for relative and absolute quantification (iTRAQ) technology. Results: Ultimately, 201 differentially expressed proteins (DEPs) were obtained, of which 47 were up regulated, and 154 were down regulated. The Gene Ontology classification and Kyoto Encyclopedia of Genes and Genomes pathway analysis were conducted to screen target DEPs associated with DFS hepatotoxicity. The regulatory relationships between DEPs and signaling pathways were embodied via a protein-protein interaction network. The results showed that the DEPs enriched in multiple pathways, which might be related to the hepatotoxicity of DFS, were "protein processing in endoplasmic reticulum," "retinol metabolism," and "glycine, serine, and threonine metabolism." Conclusions: The hepatotoxicity of DFS on broiler chickens might be achieved by inducing the apoptosis of hepatocytes and affecting the metabolism of retinol and purine. The present study could provide molecular insights into the hepatotoxicity of DFS on broiler chickens.

• The Journal of the Petrological Society of Korea
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• v.11 no.3_4
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• pp.157-168
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• 2002

In Gimcheon area of the central Yeongnam massif granite gneiss occurrs with intercalated biotite gneiss at xenolith or restite. In order to understand the evolution of the central Yeongnam massif, it is essential to have absolute age information, but not many age data are available yet. Furthermore the previous age determinations from the study area are not compatible with the outcrop relationship. In this study we determined chemical ages from the zircon grains. We obtained ages of $1970\pm$ 78(l$\sigma$)Ma from the granite gneiss, $1814\pm$77(l$\sigma$)Ma from the outer rim of a rounded zircon and 1973$\pm$97(l$\sigma$)Ma from a longish zircon, both from the biotite gneiss. These ages seem to indicate the timing of granitic magma intrusion and subsequent metamorphism. Ages of $2954\pm$ 158($l\sigma$)Ma, 2440$\pm$58(l$\sigma$)Ma, and 2219$\pm$36($l\sigma$)Ma obtained from zoned core of the rounded zircon grain from the biotite gneiss suggest various geological events before such metamorphism of the biotite gneiss. Ages in the range of 1450~1670 Ma observed in zircons of both gniesses suggest later metamorphism that the granite gneiss and the biotite gneiss experienced together. The chemical age determination by electron probe micro-analyzer of this study utilized 1$\mu\textrm{m}$ beam diameter and it seems to be a very useful age determination from the zircons with complex growth history because of superior spatial resolution.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.1 no.1
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• pp.41-51
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• 2002

As Advanced Traveler Information System(ATIS) is the kernel of the Intelligent Transportation System, it is very important how to manage data from traffic information collectors on a road and have at borough grip of the travel time's change quickly and exactly for doing its part. Link travel time can be obtained by two method. One is measured by area detection systems and the other is estimated by point detection systems. Measured travel time by area detection systems has the limitation for real time information because it Is calculated by the probe which has already passed through the link. Estimated travel time by point detection systems is calculated by the data on the same time of each. section, this is, it use the characteristic of the various cars of each section to estimate travel time. For this reason, it has the difference with real travel time. In this study, Artificial Neural Networks is used for estimating link travel time concerned about the relationship with vehicle detector data and link travel time. The method of estimating link travel time are classified according to the kind of input data and the Absolute value of error between the estimated and the real are distributed within 5$\~$15minute over 90 percent with the result of testing the method using the vehicle detector data and AVI data of Namsan Tunnel $\#$1. It also reduces Time lag of the information offered time and draws late delay generation and dissolution.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.46 no.4
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• pp.371-382
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• 2020

There have been continuous attempts to quantify sensory attributes of cosmetic products by measuring relevant physical properties. The most representative method to evaluate stickiness is to measure axial force using texture analyzer. Stickiness is known to correlate with AUC which abbreviates area under curve in the obtained axial force curve as a function of time. Recently, Normandie University research group developed in vivo stickiness evaluation method considering the characteristics of skin along with established evaluation method[8]. Based on the study, we tried to optimize in vivo stickiness evaluation method especially for cosmetic creams. The experiment was carried out on 5 different facial creams products by changing the amount and the times of rolling of creams, and the shape and material of probes. Based on the results of the sensory evaluation, the most consistent conditions were established as the optimal evaluation method. As a result, applying 70 μL of cream and rubbing 10 times for 7 s inside the 3.4 cm circle were judged to be suitable. As for the probes, spherical metallic probe was more proper due to its reproducibility. We conducted the settled method on 10 subjects to check its validity. Although the absolute values of AUC differed depending on the individuals, the AUC values were all ranked the same. Finally, for the standardization of stickiness of AUC, polyvinylpyrrolidone (PVP) was set as a reference material and we measured AUC of its aqueous solution by changing concentration. Then, the degree of stickiness recognition for 5 different creams was surveyed to check the correlation between AUC and stickiness.

• Journal of Plant Biotechnology
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• v.40 no.1
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• pp.18-26
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• 2013

Genetically modified (GM) rice Agb0101, which expresses the insecticidal toxin modified cry1Ac (mcry1Ac1) gene, was developed by the Rural Development Administration in Korea. To monitor the probable release of Agb0101 in the future, it is necessary to develop a reliable detection method. Here, we developed the PCR detection method for monitoring and tracing of GM rice. The primer pair (RBEgh-1/-2) from a starch branching enzyme (RBE4) gene was designed as an endogenous reference, giving rise to an expected PCR amplicon of 101 bp. For the qualitative PCR detection, construct- and event-specific primers were designed on the basis of integration sequence of T-DNA. Event-specific PCRs amplified specifically 5'- or 3'-junction region spanning the native genome DNA and the integrated gene construct, while none of amplified product was shown on crops, rice varieties, and other insect-resistant transgenic rice lines. The event-specific real-time PCR method was performed using TaqMan probe and plasmid pRBECrR containing both rice endogenous gene RBE4 sequence and 5'-junction sequence as the reference molecule. The absolute limit of quantification (LOQ) of real-time PCR was established with around 10 copies for one plasmid molecule pRBECrR. Thereafter, the different amounts of transgenic rice (1, 3, 5, and 10%, respectively) were quantified by using the established real-time PCR method, with a range below 19.55% of the accuracy expressed as bias, 0.06-0.40 of standard deviation (SD) and 3.80-7.01% of relative standard deviations (RSD), respectively. These results indicate that the qualitative and quantitative PCR methods could be used effectively to detect the event Agb0101 in monitoring and traceability.