• 제목/요약/키워드: Abnormality diagnosis

검색결과 234건 처리시간 0.032초

폐암 진단에서 bronchofiberscopy 의 임상적 의의 (Clinical Evaluation of Bronchofiberscopic Examination in The Diagnosis of Cancer of the Lung)

  • 조규석
    • Journal of Chest Surgery
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    • 제11권2호
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    • pp.129-134
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    • 1978
  • Two hundred and seventeen patients underwent diagnostic rigid bronchoscopy or bionchofiberscopy to evaluate the cytologic diagnosis in the lung cancer patient at the department of chest surgery of Yon-Sei university, college of the medicine from 1971 to 1977 year. One hundred and twenty cases of these patients were taken rigid bronchoscopy and ninety four cases of these patient were taken bronchofiberscopy. Cytologic examination of the sputum was done in 214 cases and sputum cytology was positive in 50 cases [23.4%]. Rigid bronchoscopy was made in 120 cases and this bronchoscopic cytology including bronchial washing and bronchial biopsy was positive in 34 cases [28.5%]. Bronchofiberscopy was performed in 94 cases and was positive in 45 cases [47.5%]. Histopathologically, 41 cases [43.6%] were epidermoid cell carcinoma, 8 cases [8.5%]of undifferentiated cell type, 12 cases [12.8%]of adenocarcinoma, 8 cases [8.5%]of alveolar cell type, and the 25 cases were undetermined. Cytologic examination of the sputum lacks the accuracy of the bronchoscopies in terms of both localization and accurate histologic indentification of the type of neoplasm. Rigid bronchoscope has the advantage of permitting identification of a tumor in a central location and of providing a sufficient amount of biopsy material for accurate diagnosis of carcinoma. However, it has the disadvantage of limiting examination to the larger, more central portions of the tracheobronchial tree. Bronchofiberscope had the advantage of examine upper lobe as well as other portions of the tracheobronchial tree which could not be visualized with the rigid bronchoscopy. A positive diagnosis in bronchofiberscopy was obtained in the highest rate, 47. 8% [45 cases]. A1 last, if a bronchogenic carcinoma is suspected on the basis of either symptoms of an abnormality on the chest film the diagnostic work-up-sputum cytology, bronchial washing, bronchoscopic biopsy, scalene node biopsy, thoracentesis and mediastinoscopy explothoracotomy etc-should precede in an attempt not only to obtain the higher positive diagnosis but also to obtain a tissue diagnosis and to evaluate the stage of the disease and to ascertain the appropriate mode of therapy.

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Statistical Techniques based Computer-aided Diagnosis (CAD) using Texture Feature Analysis: Applied of Cerebral Infarction in Computed Tomography (CT) Images

  • Lee, Jaeseung;Im, Inchul;Yu, Yunsik;Park, Hyonghu;Kwak, Byungjoon
    • 대한의생명과학회지
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    • 제18권4호
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    • pp.399-405
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    • 2012
  • The brain is the body's most organized and controlled organ, and it governs various psychological and mental functions. A brain abnormality could greatly affect one's physical and mental abilities, and consequently one's social life. Brain disorders can be broadly categorized into three main afflictions: stroke, brain tumor, and dementia. Among these, stroke is a common disease that occurs owing to a disorder in blood flow, and it is accompanied by a sudden loss of consciousness and motor paralysis. The main types of strokes are infarction and hemorrhage. The exact diagnosis and early treatment of an infarction are very important for the patient's prognosis and for the determination of the treatment direction. In this study, texture features were analyzed in order to develop a prototype auto-diagnostic system for infarction using computer auto-diagnostic software. The analysis results indicate that of the six parameters measured, the average brightness, average contrast, flatness, and uniformity show a high cognition rate whereas the degree of skewness and entropy show a low cognition rate. On the basis of these results, it was suggested that a digital CT image obtained using the computer auto-diagnostic software can be used to provide valuable information for general CT image auto-detection and diagnosis for pre-reading. This system is highly advantageous because it can achieve early diagnosis of the disease and it can be used as supplementary data in image reading. Further, it is expected to enable accurate medical image detection and reduced diagnostic time in final-reading.

가스절연 개폐장치의 내부절연 성능검증을 위한 UHF 협대역 부분방전 진단법 (UHF Narrow Band Type Partial Discharge Diagnosis Method for the Internal Insulation Performance Verification of the Gas Insulated Switchgear)

  • 송원표;김정배;김민수;정재룡;박승재;고희석
    • 대한전기학회논문지:전기물성ㆍ응용부문C
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    • 제54권9호
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    • pp.414-420
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    • 2005
  • A method for partial discharge diagnosis based on UHF narrow band type for GIS has been developed and calibrated. In generally, PD cannot be directly measured under on-line condition, but we can indirectly measure the electromagnetic wave made by PD using the high-frequency antenna. Compared with VHF band, electromagnetic waves of UHF band have a low influence for external noise in high-voltage substation. Therefore, we can detect the real abnormality with several pC in GIS using UHF narrow-band type method. For the case of no internal VHF sensor for GIS of the domestic substation, it has applied to use the external UHF sensor attached in spacer in GIS of existing substation. In this paper, we firstly described the technique of partial discharge measurement using frequency analysis and phase analysis in UHF band. Secondly, we presented the results of sensitivity test, the relationship of dBm-pC and diagnosis result of the cause of PD source by phase analysis. And then, we report the diagnosis result of partial discharge on the real GIS in domestic substation. These results make above method applicable for measurement of quantity and cause of PD for real operation GIS in high-voltage substation.

염색체 이상에 의한 반복 유산 환자에서 체외수정시술 및 착상전 유전진단을 통한 임신 성공 1례 (A Case of Successful Pregnancy in Patient with Recurrent Spontaneous Abortion by Preimplantation Genetic Diagnosis Following IVF-ET)

  • 정진석;연규선;채희동;전용필;김정훈;강병문;장윤석;목정은
    • Clinical and Experimental Reproductive Medicine
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    • 제25권2호
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    • pp.135-140
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    • 1998
  • It was reported that the etiologies of recurrent spontaneous abortion are immunologic factors, endocrinologic problems, anatomical abnormalities, genetic abnormalities, infection, and unexplained factors. Among those etiologic factors, genetic abnormalities occur in about 5% of the couples who experience recurrent spontaneous abortions, and most common parental chromosomal abnormality contributing to recurrent abortion is balanced translocation. The advent of in vitro fertilization (IVF), the development of skills associated with the handling of human embryo, and an explosion of knowledge in molecular biology have opened the possibility of early diagnosis of genetic disease in preimplantation embryos. Therefore preimplantation genetic diagnosis (PGD) is indicated for couples, infertile or not, at risk of transmitting a genetic disease. A case of successful pregnancy and term delivery by PGD using fluorescence in situ hybridization (FISH) technique in patient with recurrent spontaneous abortion due to balanced translocation is presented with brief review of literatures.

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체액 세포 도말 검사에서 메틸화 이상이 악성 중피종 진단의 부가적인 분자 표지자로서의 기능 (Methylation Abnormality in Body Fluid Cytology: A Supplemental Molecular Marker for the Diagnosis of Malignant Mesothelioma)

  • 송준선;정진경;강지혜;황일선;장세진
    • 대한세포병리학회지
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    • 제19권2호
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    • pp.126-135
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    • 2008
  • Malignant mesothelioma (MM) is a highly lethal neoplasm arising in pleura and the peritoneum and a rapid and accurate diagnosis is crucial for treatment of the disease. However, the sensitivity of cytological analysis using pleural or ascitic fluid is relatively low, yielding an accurate diagnosis in only $32{\sim}79%$ of cases. We tested the diagnostic value of epigenetic alterations in body fluid cytology as a supplement to conventional methods. Paraffin-embedded tissue blocks from 21 MM patients and associated body fluid cytology slides considered no evidence of malignancy were used to test for epigenetic alteration. Using methylation-specific PCR, we detected methylation of RASSF1A and p16 in 47.6% (10/21) of both surgically resected tumor samples, respectively. Body fluid samples of MM also showed abnormal methylation of RASSF1A and p16INK4a genes in 38.1% (8/21) and 33.3% (7/21) of cases. The concordance in the rates of RASSF1A and p16INK4a gene-methylation abnormalities determined from cytology samples and tissue samples were 61.9% (13/21) and 66.7% (14/21), respectively. Combining both genes increases the sensitivity of the test to 57.1 % (12 of 21) of cases. Our results suggest that testing for methylation abnormalities in selected individual genes or gene combinations has diagnostic value as an alternative or adjunct method to conventional cytological diagnosis.

전이 학습을 이용한 선형 이송 로봇의 정렬 이상진단 시스템 (A Diagnosis system of misalignments of linear motion robots using transfer learning)

  • 홍수빈;이영대;박아름;문찬우
    • 문화기술의 융합
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    • 제10권3호
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    • pp.801-807
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    • 2024
  • 선형 로봇은 자동화 시스템에서 부품의 이송이나 위치 결정에 널리 사용되며 보통 높은 정밀도가 요구된다. 선형 로봇을 응용한 시스템의 제작회사에서는 로봇의 이상 유무를 작업자가 판단하는데, 작업자의 숙련도에 따라 이상 상태를 판단하는 정확도가 달라진다. 최근에는 인공지능 등의 기술을 사용하여 로봇 스스로 이상을 검출하는 방법에 관한 연구가 진행되고 있다. 본 논문에서는 전이 학습을 이용하여 선형 로봇의 볼 스크류 정렬 이상과 선형 레일 정렬 이상을 검출하는 시스템을 제안하고 가속도 센서와 토크 센서 정보를 이용한 별개의 실험을 통해 제안한 시스템의 이상 검출 성능을 검증 및 비교한다. 센서로부터 얻어진 신호를 스펙트로그램 이미지로 변환한 후, 영상 인식 인공지능 분류기를 사용하여 이상의 종류를 진단하였다. 제안한 방법은 선형 로봇뿐만 아니라 일반적인 산업용 로봇에도 적용할 수 있을 것으로 기대한다.

Large Cavernous Hemangioma of the Subscapularis Muscle - A Case Report

  • Lee, Ki-Won;Lee, Hyun Il;Kim, Chung-Hwan;Kim, Tae-Kyung
    • Clinics in Shoulder and Elbow
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    • 제17권4호
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    • pp.185-189
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    • 2014
  • We report a case of intramuscular hemangioma in the subscapularis muscle and the resulting impairment of shoulder function in an adult patient. A nineteen-year-old female complained of shoulder pain and the development of a mass in the absence of previous trauma. Physical examinations, including lift-off and belly-press tests, showed abnormality. X-ray showed multiple calcifications in the front of the scapula. Magnetic resonance imaging showed a soft-tissue mass occupying almost the entire intramuscular portion of the subscapularis muscle. An arthroscopic examination excluded the possibility of a joint invasion, after which the entire mass was successfully removed by open excision. The displacement of the subscapularis by the mass was relieved after the surgery. Pathological diagnosis of the tissue confirmed a cavernous hemangioma. Both shoulder pain and function was improved after operation. There was no evidence of recurrence even at the 2-year follow-up. Rare forms of hemangioma adjacent to the shoulder joint could be successfully managed with surgical excision. Differential diagnosis, such as synovial chondromatosis, pigmented villo-nodular synovitis, and malignant sarcoma, should also be considered.

Evaluation and Management of Antenatal Hydronephrosis

  • Hong, Young Kwon;Lee, Jun Ho
    • Childhood Kidney Diseases
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    • 제19권1호
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    • pp.8-13
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    • 2015
  • Antenatal hydronephrosis (ANH) is one of the most common abnormal findings detected on prenatal ultrasound (US), and it has been reported in 1-5% of all pregnancies. The likelihood of significant postnatal pathologic abnormality in the urinary tract correlates with the degree of anterior-posterior diameter (APD) according to the gestational age. Detection of urologic anomalies prenatally permits fetal interventions that avoid complications in rare cases of bladder outlet obstruction with oligohydramnios even though their final benefits still remain controversial. There is no clear consensus on the extent and mode of postnatal imaging after a diagnosis of ANH. US is the mainstay of the postnatal evaluation and helps guide further testing with voiding cystourethrography (VCUG) and diuretic renography. Although most algorithms continue to recommend generous VCUG for identification of lower urinary tract anomalies, VCUG may be safely reserved for high grade ANH cases or any grade of ANH with dilated distal ureter without increasing the risk of urinary tract infection (UTI). There are conflicting studies about efficacy of postnatal prophylactic antibiotics. It still seems reasonable to consider use of a prophylactic antibiotic to prevent infant UTIs in high-risk populations, such as females and uncircumcised males with high grades of hydronephrosis, hydroureteronephrosis, or vesicouretral reflux.

악관절증의 진단을 위한 역동적 자기공명 영상의 이용 및 증례 (Diagnostic Reliability & Case Reports Of The Dynamic MRI For Temporomandibular Joint Disease)

  • 박진호;진병로;변우목
    • Journal of Yeungnam Medical Science
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    • 제12권1호
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    • pp.141-148
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    • 1995
  • 본 교실에서는 측두하악관절주위의 동통, 관절 잡음동의 증상을 주소로 내원한 환자들에 있어서 역동적 자기공명영상의 촬영을 시행하여 관절원판의 전방변위와 형태적 이상 및 주위 구조물들과의 관계를 분석한 결과 근육성 동통기능장애와의 감별뿐만 아니라 환자의 중상에 따른 관절 내부 장애의 정도를 파악할 수 있었으며 악기능시의 구조적 이상, 장애의 원인 등을 판독하여 치료의 방침을 세우는데 있어 매우 유용한 정보를 얻을 수 있었기에 보고 하는 바이다.

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Applying Mahalanobis Taguchi System for Analyzing the Effect between University Admission Requirements and Student's Academic Accomplishment

  • 홍정의
    • 대한안전경영과학회:학술대회논문집
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    • 대한안전경영과학회 2010년도 추계학술대회
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    • pp.233-243
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    • 2010
  • Mahalanobis Taguchi System (MTS) is a pattern information technology, which has been used in different diagnostic applications to make quantitative decisions by constructing a multivariative measurement scale using data analytic methods. In MTS approach, Mahalanobis distance (MD) is used to measure the degree of abnormality of patterns and principles of Taguchi methods are used to evaluate accuracy of predictions based on the scale constructed. The advantage of MD is that it takes into consideration the correlations between the variables and this consideration is very important in pattern analysis. The purpose of this study is constructing admission diagnosis system and define the effect of admission requirements for student's academic accomplishment.

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