• Asian Pacific Journal of Cancer Prevention
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• v.17 no.6
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• pp.2941-2946
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• 2016

Background: The limitations of total serum PSA values remain problematic, especially after an initial negative prostate biopsy. In this prospective study of Chilean men with a continued suspicion of prostate cancer due to a persistently elevated total serum PSA, abnormal digital rectal examination and initial negative prostate biopsy were compared with the use of the on-line Chun nomagram, detection of primary malignant circulating prostate cells (CPCs) and free percent PSA to predict a positive second prostate biopsy. We hypothesized that men negative for circulating prostate cells have a small risk of clinically significant prostate cancer and thus may be conservatively observed. Men positive for circulating prostate cells should undergo biopsy to confirm prostate cancer. Materials and Methods: Consecutive men with a continued suspicion of prostate cancer underwent 12 core TRUS prostate biopsy; age, total serum PSA and percentage free PSA and Chun nomagram scores were registered. Immediately before biopsy an 8ml blood simple was taken to detect primary mCPCs. Mononuclear cells were obtained by differential gel centrifugation and identified using double immunostaining with anti-PSA and anti-P504S. Biopsies were classifed as cancer/no-cancer, mCPC detecton test as negative/positive and the total number of cells/8ml registered. Areas under the curve (AUC) for percentage free PSA, Chun score and CPCs were calculated and compared. Diagnostic yields were calculated with reference to the number of possible biopsies that could be avoided and the number of clinically significant cancers that would be missed. Results: A total of 164 men underwent a second biopsy; 41 (25%) had cancer; the AUCs were 0.65 for free PSA, 0.76 for the Chun score and 0.87 for CPC detection, the last having a significantly superior prediction value (p=0.01). Using cut off values of free PSA <10%, Chun score >50% and ${\geq}1$ CPC detected, CPC detection had a higher diagnostic yield. Some 4/41 cancers complied with the criteria for active surveillance, free PSA and the Chun score missed a higher number of significant cancers when compared with CPC detection. Conclusions: Primary CPC detection outperformed the use of free PSA and the Chun nomagram in predicting clinically significant prostate cancer at repeat prostate biopsy.

• Journal of Korea Multimedia Society
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• v.15 no.11
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• pp.1330-1340
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• 2012

In this paper, a new algorithm is proposed for the heart valves stenosis region detection using heart sounds. Many researches for detecting primary components or removing heart murmurs have been studied, but their performances are degraded at abnormal heart sounds such as aortic stenosis and mitral stenosis because of large heart murmurs. In this paper, heart murmur detection method is proposed based on noise intensity function. The proposed noise intensity function detect the primary components S1, S2, then set session up using S1, S2. And then noise intensity function was computed using autocorrelation value of each session. The proposed noise intensity function estimated noise intensity of each sessions and detected heart murmurs. According to simulation results, the proposed algorithm has better performance than former study for detecting heart valve stenosis region.

• Journal of Korea Water Resources Association
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• v.51 no.8
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• pp.703-711
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• 2018

Water distribution system (WDS) pipe bursts are caused from excessive pressure, pipe aging, and ground shift from temperature change and earthquake. Prompt detection of and response to the failure event help prevent large-scale service interruption and catastrophic sinkhole generation. To that end, this study proposes a improved Western Electric Company (WECO) method to improve the detection effectiveness and efficiency of the original WECO method. The original WECO method is an univariate Statistical Process Control (SPC) technique used for identifying any non-random patterns in system output data. The improved WECO method multiples a threshold modifier (w) to each threshold of WECO sub-rules in order to control the sensitivity of anomaly detection in a water distribution network of interest. The Austin network was used to demonstrated the proposed method in which normal random and abnormal pipe flow data were generated. The best w value was identified from a sensitivity analysis, and the impact of measurement frequency (dt = 5, 10, 15 min etc.) was also investigated. The proposed method was compared to the original WECO method with respect to detection probability, false alarm rate, and averaged detection time. Finally, this study provides a set of guidelines on the use of the WECO method for real-life WDS pipe burst detection.

• Journal of Preventive Medicine and Public Health
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• v.27 no.4 s.48
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• pp.747-761
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• 1994

Workers' periodic health examination is the main tools used to manage the health problems of most workers in Korea. The most common health problem found in workers' periodic health examination is liver disorder. Liver disorder is also one of the most common health problems in general population and one of the leading causes of mortality in adult population. Regulation proposed by government (No. 207, Ministry of Labor, 1992) defines the criteria for selection of workers with the liver dysfunction for further evaluative examination and the examination items used for diagnosis of the workers with liver dysfunction. This study was designed to evaluate the proficiency of each examination items presently defined in Regulation and propose the optimal examination items for detection of the liver disorders found by workers' periodic health examination. Study subjects are 186 workers with abnormal liver function tests in screening examination of workers' periodic health examination. Questionnaire survey including past history of liver disorder, drinking history, height and weight was done. Physical examination by physician, routine test items defined by Regulation (SGOT, SGPT, $\gamma$-GTP, protein, albumin, total and direct bilirubin, alkaline phosphatase, $\alpha$-feto protein, HBsAg and anti-HBs), anti-HCV antibody test and liver ultrasonography were done. Results are as follows; 1. Result of evaluative examination utilizing only the items defined in Regulation was; There were 75 workers with suspected live. disorder(40.3%), 63 with no liver dysfunction (33.9%), 13 with suspected hepatitis B(7.0%), 10 workers with hepatitis B(5.4%), 10 workers with hepatitis B carrier state(5.4%), 10 with alcoholic liver disorders(5.4%), 5 with fatty liver(2.7%). When alternative diagnostic criteria applying additional examination items (drinking history, body mass index, anti-HCV antibody and ultrasonography) diagnosability of liver disorder was increased. When all four items were included, final results were; 23 workers (17.8%) with hepatitis B (10 carriers, 13 suspects and 10 hepatitis B), 10 (5.4%) with hepatitis C(4 carriers, 5 suspects and 1 hepatitis C), 13(7.0%) with alcoholic liver disorder, 45(24.2%) with fatty liver (40 suspects, 5 fatty liver), 410%) with suspected liver disorders and 44 (23.7%) with normal liver. 2. Of examination items defined by Regulation, only SGOT, SGPT, $\gamma$-GTP and HBsAg were significantly different in abnormal rate and mean value, and all other laboratory findings did not showed significant difference between two groups. Drinking history, body mass index and anti-HCV antibody test which are the items that authors included in this study, also showed significant difference between two groups. Utilization of body mass index (BMI) for abnormal liver function group in diagnosis of fatty liver had high specificity (97.6%) but sensitivity (22.3%) was low. Therefore we suggest that SGOT, SGPT, $\gamma$-GTP, HBsAg, alcohol drinking history, BMI and anti-HCV Ab were useful for diagnosis of liver disorders among worker's periodic health examination.

• Korean Journal of Remote Sensing
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• v.36 no.5_1
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• pp.667-677
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• 2020

Crop water stress can be detected based on soil moisture content, crop physiological characteristics and remote-sensing technology. The detection of crop water stress is an important issue for the accurate assessment of yield decline. The crop water stress index (CWSI) has been introduced based on the difference between leaf and air temperature. In this paper, drone-based thermal infrared image was used to map of crop water stress in water control plot (WCP) and water deficit plot (WDP) over spring chinese cabbage fields. The spatial distribution map of CWSI was in strong agreement with the abnormal growth response factors (plant height, plant diameter, and measured value by chlorophyll meter). From these results, CWSI can be used as a good method for evaluation of crop abnormal growth monitoring.

• The Korean Journal of Nuclear Medicine
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• v.34 no.3
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• pp.234-242
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• 2000

Purpose: Tc-99m MIBI scintimammography has been validated as an useful non-invasive diagnostic tool for the primary breast cancer. But most studies have included small population of patients. We have experienced a large study population and investigated the diagnostic usefulness of Tc-99m MIBI scintimammography in detection of primary breast cancer and axillary lymph node metastasis. Materials and Methods: This study included 305 patients who underwent scintimammogtaphy for palpable breast masses or abnormal radiologic findings. Tc-99m MIBI scintimammography was performed 10 minutes after intravenous injection of 925 MBq of Tc-99m MIBI. If the early image revealed abnormal finding, 3 hour delayed image was also acquired. We calculated early and delayed lesion to non-lesion ratios (L/N). The pathologic diagnosis was obtained from surgical operation or FNAB and compared with the results of Tc-99m MIBI scintimammography. Results: Malignant breast diseases were 155 and benign ones were 150. Tc-99m MIBI scintimammography revealed 132 true positive, 23 false negative, 10 false positive, and 140 true negative cases. The sensitivity, specificity, positive predictive value and negative predictive value for the primary breast cancer detection were 85.2%, 93.4%, 92.9%, and 85.9%, respectively. The sensitivity, specificity, positive predictive and negative predictive values of Tc-99m MIBI scintimammography in detecting metastatic axillary lymph node involvement were 22%, 90.4%, 61.9% and 62.3%, respectively. Early L/N of malignant breast disease was significantly higher than that of benign one ($2.44{\pm}0.97\;vs\;1.94{\pm}0.78$, p=0.01). Delayed L/N had no significant difference between malignant and benign breast diseases ($1.94{\pm}0.52\;vs\;1.91{\pm}0.73$, p=0.43). Conclusion: Our study revealed that Tc-99m MIBI scintimammography was an useful diagnostic tool for the diagnosis of breast cancer. And early L/N ratio might provide complementary role in the detection of breast cancer. But the Tc-99m MIBI scintimammography had limited value in the detection of small breast cancer (less than 1 cm) and axillary lymph node metastasis.

• Atmosphere
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• v.26 no.4
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• pp.541-551
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• 2016

A real-time quality control algorithm for $PM_{10}$ concentration measured by Continuous Ambient Particulate Monitor (FH62C14, Thermo Fisher Scientific Inc.) has been developed. The quality control algorithm for $PM_{10}$ data consists of five main procedures. The first step is valid value check. The values should be within the acceptable range limit. Upper ($5,000{\mu}g\;m^{-3}$) and lower ($0{\mu}g\;m^{-3}$) values of instrument detectable limit have to be eliminated as being unrealistic. The second step is valid error check. Whenever unusual condition occurs, the instrument will save error code. Value having an error code is eliminated. The third step is persistence check. This step checks on a minimum required variability of data during a certain period. If the $PM_{10}$ data do not vary over the past 60 minutes by more than the specific limit ($0{\mu}g\;m^{-3}$) then the current 5-minute value fails the check. The fourth step is time continuity check, which is checked to eliminate gross outlier. The last step is spike check. The spikes in the time series are checked. The outlier detection is based on the double-difference time series, using the median. Flags indicating normal and abnormal are added to the raw data after quality control procedure. The quality control algorithm is applied to $PM_{10}$ data for Asian dust and non-Asian dust case at Seoul site and dataset for the period 2013~2014 at 26 sites in Korea.

• Transactions of the Korean Society of Automotive Engineers
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• v.1 no.3
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• pp.12-21
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• 1993

In recent years, high efficiency, high performance, and low pollutant emmision engines have been developed. Knock phenomenon has drawn interests because it became an hinderance to engine power and efficiency increase through higher compression ratio. Knock phenomenon is an abnormal combustion originated from autoignition of unburned gas in the end-gas region during the later stage of combustion process and accompanied a high pitched metallic noise. And this phenomenon is characterized by knock occurrence percentage, knock occurrence angle and knock intensity. A four cylinder spark ignition engine is used in our experiment, and its combustion chamber pressure is measured at various engine speeds, ignition timing. The data are analyzed by numerous methods in order to select the optimum methods and to achieve better understanding of knock characteristics. Methods using band-pass filter, third derivative and step method are shown to be the most suitable, while methods using frequency analysis are shown to be unsuitable. Because step method only uses signals above threshold value during knocking condition, pressure signal analyses with this method show good signal-to-noise ratio.

• Journal of Satellite, Information and Communications
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• v.11 no.3
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• pp.51-57
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• 2016

Many kinds of telemetry should be monitored to check the state of spacecraft and it leads the time consumption. However, it is very important to define the status of satellite in short time because the contact number and time of low earth orbit satellite is limited. Also, on-board fault management should be prepared for non-contact operation because of the sever space environment. In this paper, on-board and ground autonomous operation method for the safety enhancement is described. Immediate fault detection and response is possible in ground by explicit anomaly detection through satellite event and error information. Also, satellite operation assistant system is proposed for ground autonomy that collect event sequence in accordance with related telemetry and recommend or execute an appropriate action for abnormal state. Critical parameter monitoring method with checking rate, mode and threshold is developed for on-board autonomous fault management. If the value exceeds the limit, pre-defined command sequence is executed.

• International Journal of Safety
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• v.11 no.2
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• pp.15-21
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• 2012

This paper is aimed to develop an electrical fire detection system (EFDS) which can analyze the possibility of electrical fire for overcurrent, leakage current and arc signals of panel board in traditional market shop. The EFDS adopted fuzzy logic and precursory data for overcurrent, leakage current and arc signals to evaluate the possibility of electrical fire. The signals are obtained directly from panel board in traditional market shops and fuzzy membership function is obtained from experiment, simulation, expert's advice. The overcurrent data is acquired by thermal data of normal and abnormal states (partial disconnection) on the insulated electrical wire, in accordance with the increase of the current signal, The leakage current data is obtained under various environments. The arc signal is acquisited by waveforms of instantaneous value in time domain and frequency band in frequency domain. The Fuzzy algorithm for DB of EFDS consists of fuzzification, inference engine by Mamdani's method and defuzzification by center of gravity method. In order to verify the performance and reliability of EFDS, it was applied to Jeon-Ju traditional market shops (90 shops) in Korea. Results show that EFDS in this paper is useful in alarming the fire case, which will prevent severe damage to human beings and properties, and reduce the electrical fires in a vulnerable area of electrical disaster.