• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2022년도 학술발표회
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• pp.208-208
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• 2022

Recently, the frequency of abnormal weather due to complex factors such as global warming is increasing frequently. From the past rainfall patterns, it is evident that climate change is causing irregular rainfall patterns. This phenomenon causes difficulty in predicting rainfall and makes it difficult to prevent and cope with natural disasters, casuing human and property damages. Therefore, accurate rainfall estimation and rainfall occurrence time prediction could be one of the ways to prevent and mitigate damage caused by flood and drought disasters. However, rainfall prediction has a lot of uncertainty, so it is necessary to understand and reduce this uncertainty. In addition, when accurate rainfall prediction is applied to the rainfall-runoff model, the accuracy of the runoff prediction can be improved. In this regard, this study aims to increase the reliability of rainfall prediction by analyzing the uncertainty of the Korean rainfall ensemble prediction data and the outflow analysis model using the Limited Area ENsemble (LENS) and the Grid based Rainfall-runoff Model (GRM) models. First, the possibility of improving rainfall prediction ability is reviewed using the QM (Quantile Mapping) technique among the bias correction techniques. Then, the GRM parameter calibration was performed twice, and the likelihood-parameter applicability evaluation and uncertainty analysis were performed using R², NSE, PBIAS, and Log-normal. The rainfall prediction data were applied to the rainfall-runoff model and evaluated before and after calibration. It is expected that more reliable flood prediction will be possible by reducing uncertainty in rainfall ensemble data when applying to the runoff model in selecting behavioral models for user uncertainty analysis. Also, it can be used as a basis of flood prediction research by integrating other parameters such as geological characteristics and rainfall events.

• 셀메드
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• 제13권14호
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• pp.19.1-19.16
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• 2023

Objectives: To compare the efficacy of polyherbal Unani formulations in heavy menstrual bleeding due to endometrial hyperplasia. Methodology: A prospective, randomized comparative trial was conducted at Govt. Nizamia Tibbi College. Group A (n=20) received Itrifal Aftimoon 5g orally BID from menstruation day 3 to day 21 plus suprapubic Marham Dakhilyun application and per vaginally Marham Dakhilyun (5g) and Roghan Gul (10ml) application from menstruation day 5 to day 14. Group B (n=20) received Gulnar Farsi (2g), Phitakri Biryan (0.25g), Dammul Aqwain (0.25g), and Geru (2g), 2.5g powder orally BID, menstruation day 3 for 20 days plus Douche Bargh Sambhalu then Ḥamūl of Safuf Mazu (2g), Kalijiri (2g) and Roghan Gul (10ml) from menstruation day 3 to day 12 for 3 consecutive cycles. The primary outcome was pelvic ultrasound findings of endometrial thickness. The secondary outcome measures were improvement in haemoglobin percentage, change in menstrual flow and menstrual pattern. The level of significance was 5%. Results and conclusion: The intragroup comparison showed that the mean endometrial thickness at baseline and after treatment in groups A and B was extremely significantly different (P<0.0001). The intragroup comparison showed the mean haemoglobin percent at baseline and after treatment in group, A was significantly different (P<0.0001). After treatment, 50% and 60% of participants had normal duration and menstrual blood loss after treatment from baseline in Groups A and B respectively. However, further, phase II and III randomized standard controlled trials in larger samples are recommended to assess the efficacy of these group medicines.

• Journal of Animal Science and Technology
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• 제65권4호
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• pp.792-803
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• 2023

This study aimed to assess the impact of weather events on the sorghum-sudangrass hybrid (Sorghum bicolor L.) cultivar production trend in the central inland region of Korea during the monsoon season, using time series analysis. The sorghum-sudangrass production data collected between 1988 and 2013 were compiled along with the production year's weather data. The growing degree days (GDD), accumulated rainfall, and sunshine duration were used to assess their impacts on forage production (kg/ha) trend. Conversely, GDD and accumulated rainfall had positive and negative effects on the trend of forage production, respectively. Meanwhile, weather events such as heavy rainfall and typhoon were also collected based on weather warnings as weather events in the Korean monsoon season. The impact of weather events did not affect forage production, even with the increasing frequency and intensity of heavy rainfall. Therefore, the trend of forage production for the sorghum-sudangrass hybrid was forecasted to slightly increase until 2045. The predicted forage production in 2045 will be 14,926 ± 6,657 kg/ha. It is likely that the damage by heavy rainfall and typhoons can be reduced through more frequent harvest against short-term single damage and a deeper extension of the root system against soil erosion and lodging. Therefore, in an environment that is rapidly changing due to climate change and extreme/abnormal weather, the cultivation of the sorghum-sudangrass hybrid would be advantageous in securing stable and robust forage production. Through this study, we propose the cultivation of sorghum-sudangrass hybrid as one of the alternative summer forage options to achieve stable forage production during the dynamically changing monsoon, in spite of rather lower nutrient value than that of maize (Zea mays L.).

• 대한영상의학회지
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• 제85권3호
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• pp.505-519
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• 2024

MRI는 골수의 평가에 있어 가장 예민도가 높은 검사로서 골수 질환의 진단에 있어 매우 중요한 역할을 한다. 그러나, 소아 영상을 자주 접하지 않는 영상의학과 의사들에게는 종종 정상 골수와 병적 골수의 구분이 어려울 수 있고, 소아의 흔한 악성질환인 백혈병이나 신경모세포종의 전이 등 골수를 침범하는 질환들이 임상적으로 다양한 근골격계 증상으로 발현하여 근골격 MRI 검사를 통해 진단되기도 한다. 소아에서 시행되는 MRI를 정확하게 판독하려면 골수의 정상 구성 성분에 대한 이해뿐만 아니라 나이에 따른 골수의 변화(age-related developmental change)와 소아에서 흔하게 골수를 침범하는 질환들에 대한 이해가 중요하다. 본 종설에서는 정상 골수의 구성과 소아 골수의 정상 및 비정상 MRI 소견을 기술하고 백혈병, 신경모세포종의 전이 등의 악성 골수 질환을 중심으로 임상 증례들을 고찰하고자 한다.

• 만화애니메이션 연구
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• 통권37호
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• pp.197-219
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• 2014

디즈니 애니메이션 <겨울왕국>이 한국에서 개봉된 애니메이션 사상 첫 천만 관객을 동원했다. 겨울왕국은 주제곡 'let it go'의 열풍과 엘사, 안나, 울라프의 캐릭터 상품들을 비롯해 각종 신드롬까지 낳고 있다. 그렇다면 겨울왕국이 어떤 의미를 생성하고 있기에 이토록 한국에서 선풍적인 인기를 끌었는지를 생각해 볼 필요가 있다. 이 연구는 겨울왕국이 관객에게 전달하고자 하는 가치와 겨울왕국이 생성하는 의미는 무엇인지를 그레마스의 행위소 모형과 기호사각형을 이용하여 살펴보고자 한다. 행위소 모형으로 <겨울왕국>의 안나와 엘사를 분석한 결과, 안나는 엘사와의 관계회복과 아렌델의 여름을 되찾기를 욕망한다. 이것은 엘사에 대한 사랑과 아렌델사람들을 위한 사랑으로 말하여질 수 있다. 한편, 엘사는 자신의 설빙능력으로 인해 스스로를 가두기는 하지만 항상 자유를 갈망한다. 즉 엘사는 자신의 설빙능력을 제어하는 방법을 알아내 자신의 설빙능력으로 자유로워지를 욕망하는 것이다. 이러한 안나와 엘사의 욕망은 진실한 사랑의 행동을 통해 획득되어지며, <겨울왕국>에서 모든 갈등의 해결책은 진실한 사랑의 행동이다. 기호사각형으로 <겨울왕국>의 의미를 분석한 결과, <겨울왕국>은 현재의 비정상적인 삶을 과거의 정상적인 삶으로 바꾸고자 하는 과거지향적인 가치를 창출한다. 현재의 삶-한 여름에 추운 겨울이 찾아오고, 자매간의 소통이 단절되며, 비정상의 상태를 의도적으로 이용하여 자신의 이익을 취하려는 사람들-을 과거의 돈독했던 자매간의 우애와 순리적인 계절인 아렌델의 여름으로 바꾸고자 하는 것이다. <겨울왕국>에서 말하고자 하는 과거를 지향하는 가치는 21세기를 살아가는 우리의 현실과 비슷하다. 들었어도 믿기 어려운 소식들, 불안한 정세 등이 난무하는 현실에서 어렵고 힘들어도 정과 희망이 넘쳐났던 과거의 삶으로 돌아가고 싶은 우리의 정서와 맞물렸기 때문에 국내에서 <겨울왕국>이 승승장구하지 않았나 싶다.

• Childhood Kidney Diseases
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• 제14권1호
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• pp.22-31
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• 2010

목 적 : Alport증후군 환자의 사구체 기저막의 형태학적 변화 및 사구체 상피세포의 구조 변화에 따른 임상지표간의 상관 관계를 알아보고자 하였다. 방 법 : Alport 증후군으로 확진된 15명의 환자를 대상으로 하였다. 사구체 기저막을 형태학적 변화에 따라 1) 정상(C1), 2) minor alteration: widening of lamina rara interna or externa without lamina densa changes (C2), 3)nonspecific splitting of lamina densa (C3), 4) basket-weave pattern of lamina densa splitting (C4)의 4가지 범주로 나누고 각 범주에 해당하는 사구체 기저막의 비율을(%) 측정하였다. 또한 각 범주의 사구체 기저막에서 사구체 기저막 $10\;{\mu}m$에 대한 상피세포의 세과여극(slit pore)의 밀도를 구하였고, 나이에 따른 사구체 기저막의 형태학적 변화를 살펴보았다. 결 과 : 요 중 단백질 배설량과 정상 기저막 소견(C1) 사이는 역비례 관계를 보였고(P<0.05), 요 중 단백질 배설량과 비정상 사구체 기저막 소견(C2+C3+C4) 사이는 정비례 관계를 보였다(P<0.05). 비정상적 기저막 소견을 보이는 각 범주와 단백뇨나 크레아티닌 청소율과는 의미 있는 상관관계가 없었다. 크레아티닌 청소율과 정상 사구체 기저막(C1)의 비율과의 관계는 통계적인 의미가 없었고(P=0.085), 비정상 사구체 기저막(C2+C3+C4)의 비율과도 통계적으로 의미가 없었다(P=0.080). 신생검 당시의 나이와 사구체 기저막의 형태학적 변화도 상관관계가 없었다. 결 론 : Alport 증후군 환자에서 사구체 기저막의 변화는 단백뇨와 관련성이 있지만 사구체 상피세포 구조와 사구체여과율과는 관련성이 없었다.

• 한국지리정보학회지
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• 제23권3호
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• pp.263-274
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• 2020

한국 남동해역은 매년 하계에 집중적으로 냉수대가 형성되어 빈번한 이상해황이 발생한다. 본 연구에서는 이 해역에서 발생하는 표층수온 분포의 공간 변화를 분석하기 위해 2018년 6월에서 9월까지 고리와 정자 부이에서 관측한 해양현장 수온 데이터와 GHRSST Level 4 재분석 해수면 온도(sea surface temperature: SST) 자료를 이용하였다. 부이 자료는 두 지점의 시계열적 수온 변동 분석에, GHRSST 자료는 연구해역 전반에 걸친 일별 SST의 분산과 가중공간중심(weighted mean center: WMC)을 계산하는데 이용하였다. 부이의 수온이 낮아지면 연구해역 SST의 분산이 증가하는 경향을 보였으나, 전 기간 일치하게 나타나지는 않았다. 이는 GHRSST가 재분석 자료로 연안의 민감한 수온변화를 반영하지 못하기 때문이다. 이와 같이 전 해역의 SST 변화를 대표하는 통계적 분산만으로는 연안의 국지적인 소규모의 수온변화를 파악하거나, 냉수대 발생해역의 위치 및 범위를 탐지하기에는 한계가 있다. 따라서 차가운 수괴가 발생하는 공간적인 위치를 정량적으로 파악하기 위해 WMC를 활용하여 분석한 결과 냉수대가 발생했을 때, WMC가 연구해역의 공간중심(mean center: MC)으로부터 북서 해역 쪽에 위치하였다. 이는 SST의 WMC 위치 정보를 통해 차가운 표층수온의 분포가 어디에서 어느 정도 나타나는지를 정량적으로 파악할 수 있음을 의미하며, 향후 냉수대 규모 및 지역 확산 범위 탐지에 WMC의 활용 가능성을 알 수 있었다.

• 한국해양공학회지
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• 제33권6호
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• pp.590-596
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• 2019

Numerous deaths and substantial property damage have occurred recently due to frequent disasters of the highest intensity according to the abnormal climate, which is caused by various problems, such as global warming, all over the world. Such large-scale disasters have become an international issue and have made people aware of the disasters so they can implement disaster-prevention measures. Extensive information on disaster prevention actively has been announced publicly to support the natural disaster reduction measures throughout the world. In Japan, diverse developmental studies on disaster prevention systems, which support hazard map development and flood control activity, have been conducted vigorously to estimate external forces according to design frequencies as well as expected maximum frequencies from a variety of areas, such as rivers, coasts, and ports based on broad disaster prevention data obtained from several huge disasters. However, the current reduction measures alone are not sufficiently effective due to the change of the paradigms of the current disasters. Therefore, in order to obtain the synergy effect of reduction measures, a study of the establishment of an integrated system is required to improve the various disaster prevention technologies and the current disaster prevention system. In order to develop a similar typhoon search system and establish a disaster prevention infrastructure, in this study, techniques will be developed that can be used to forecast typhoons before they strike by using artificial intelligence (AI) technology and offer primary disaster prevention information according to the direction of the typhoon. The main function of this model is to predict the most similar typhoon among the existing typhoons by utilizing the major typhoon information, such as course, central pressure, and speed, before the typhoon directly impacts South Korea. This model is equipped with a combination of AI and DNN forecasts of typhoons that change from moment to moment in order to efficiently forecast a current typhoon based on similar typhoons in the past. Thus, the result of a similar typhoon search showed that the quality of prediction was higher with the grid size of one degree rather than two degrees in latitude and longitude.

• 유통과학연구
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• 제14권1호
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• pp.93-102
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• 2016

Purpose - The purpose of paper is studying the static and dynamic side for long-term memory storage properties, and increase the explanatory power regarding the long-term memory process by looking at the long-term storage attributes, Korea Composite Stock Price Index. The reason for the use of GPH statistic is to derive the modified statistic Korea's stock market, and to research a process of long-term memory. Research design, data, and methodology - Level shifts were subjected to be an empirical analysis by applying the GPH method. It has been modified by taking into account the daily log return of the Korea Composite Stock Price Index a. The Data, used for the stock market to analyze whether deciding the action by the long-term memory process, yield daily stock price index of the Korea Composite Stock Price Index and the rate of return a log. The studies were proceeded with long-term memory and long-term semiparametric method in deriving the long-term memory estimators. Chapter 2 examines the leading research, and Chapter 3 describes the long-term memory processes and estimation methods. GPH statistics induced modifications of statistics and discussed Whittle statistic. Chapter 4 used Korea Composite Stock Price Index to estimate the long-term memory process parameters. Chapter 6 presents the conclusions and implications. Results - If the price of the time series is generated by the abnormal process, it may be located in long-term memory by a time series. However, test results by price fixed GPH method is not followed by long-term memory process or fractional differential process. In the case of the time-series level shift, the present test method for a long-term memory processes has a considerable amount of bias, and there exists a structural change in the stock distribution market. This structural change has implications in level shift. Stratum level shift assays are not considered as shifted strata. They exist distinctly in the stock secondary market as bias, and are presented in the test statistic of non-long-term memory process. It also generates an error as a long-term memory that could lead to false results. Conclusions - Changes in long-term memory characteristics associated with level shift present the following two suggestions. One, if any impact outside is flowed for a long period of time, we can know that the long-term memory processes have characteristic of the average return gradually. When the investor makes an investment, the same reasoning applies to him in the light of the characteristics of the long-term memory. It is suggested that when investors make decisions on investment, it is necessary to consider the characters of the long-term storage in reference with causing investors to increase the uncertainty and potential. The other one is the thing which must be considered variously according to time-series. The research for price-earnings ratio and investment risk should be composed of the long-term memory characters, and it would have more predictability.

• 동의생리병리학회지
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• 제21권5호
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• pp.1118-1126
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• 2007

The purpose of this study was to examine the anti allergic effect in vivo and in vitro, and to observe single and four weeks repeated toxicity in mice of Bangpung-galgeun-tang (BGT). We investigated anti DNP IgE-mediated passive cutaneous anaphylaxis in rodents and compound 48/80-induced active systemic anaphylatic shock in mice after oral administration with BGT of 0.4 g/kg and 0.8 g/kg for 8 days, and also examined MTT assay, ${\beta}-hexosaminidase$ activity, IL-4 and $TNF-{\alpha}$ from RBL-2H3 and $TNF-{\alpha}$ from Raw264.7 after pre-treatment with BGT of 0.25 mg/ml, 0.5 mg/ml, 1 mg/ml and 2 mg/ml. To ascertain safety and toxicity of BGT, we divided into single and four weeks repeated administration test. In single test, three groups were administrated different dosages and routes (2 g/kg/i.p., 4 g/kg/i.p. and 15 g/kg /p.o.) of BGT, and in four weeks repeated test, 0.8 g/kg BGT was administrated. Control groups were administrated with only saline according to on Korean Food and Drug Administration, respectively. We observed attentively motality, abnormal clinical sign, body weight change, organ weight, AST and ALT of mice after BGT administration. BGT inhibited passive cutaneous anaphylaxis and active systemic anaphylatic shock by oral administration. All the concentrations of BGT from 0.25 to 2 mg/ml didn't have an effect on cell viability and cytotoxicity. In RBL-2H3, ${\beta}-hexosaminidase$ release, IL-4 and $TNF-{\alpha}$, and in Raw264.7, $TNF-{\alpha}$ were significantly reduced by treated all concentrations of BGT. During toxicity experiment period, there was no difference in body weight change, organ weight, AST and ALT among different dose groups. Death were found 3 mice from day 2 to day 3 in single test i.p. group. (2 g/kg, 4 g/kg). Several individuals of single test i.p. group were observed that decreased locomotor activity, exophthalmos, bloodshot eyes, loss of eyesight and so on in early period after administration. But there was no difference in clinical signs among p.o. group. These results indicate that BGT have inhibition effects on allergy and suggest that no observable effect level of the test orally administration was considered to be more than 2 g/kg in mice under the conditions employed in this study.