• 한국수자원학회:학술대회논문집
• /
• 한국수자원학회 2021년도 학술발표회
• /
• pp.126-126
• /
• 2021

Stormwater reduction plays an important role in the safety and resilience to flooding in urban areas. Due to rapid climate change, the world is experiencing abnormal climate phenomena, and sudden floods and concentrated torrential rains are frequently occurring in urban basins and the amount of outflow due to stormwater increases. In addition, the damage caused by urban flooding and inundation due to extreme rainfall exceeding the events that occurred in the past increases. To solve this problem, water supply, drainage, and water supply for sustainable urban development, the water management paradigm is shifting from sewage maintenance to water circulation and water-sensitive cities. So, in this study, The purpose of this study is to examine measures to increase the resilience of urban ecosystem systems for urban excellence reduction by analyzing the effects of green infra structures and LID techniques and evaluating changes in resilience. In this study, for simulating and analysis of runoff for various stormwater patterns and LID applications, Storm Water Management Model (SWMM) was used.

• Journal of Digestive Cancer Research
• /
• 제5권1호
• /
• pp.50-54
• /
• 2017

Pancreatic neuroendocrine tumors are rare pancreatic neoplasms comprising 1-2% of all pancreatic tumors and typically present high attenuating mass on arterial and venous phase images, due to their rich capillary network. A 70-year-old South Korean female visited our hospital presenting with jaundice and dark urine color. She had received an operation for treatment of small bowel perforation seven years ago. On physical examination, icteric sclera was observed but otherwise unremarkable. Laboratory tests were abnormal liver function test and suspected obstructive jaundice. Computed tomography revealed 4 cm sized cystic mass lesion with homogeneous low attenuation in the head of pancreas and distal common bile duct was compressed by the mass. During review of past medical records, we found that the mass was observed and measured about 1.7 cm seven years ago. To resolve obstructive jaundice, pylorus preserving pancreaticoduodenectomy was performed and diagnosed with well differentiated pancreatic neuroendocrine carcinoma with intermediate grade.

• 한국자원식물학회:학술대회논문집
• /
• 한국자원식물학회 2020년도 춘계학술대회
• /
• pp.9-9
• /
• 2020

Many modern people are exposed to chronic inflammatory diseases, such as inflammatory bowel disease (IBD), atopic dermatitis and immune disorder. Among those chronic diseases, the incidence ratio of IBD has been increased. IBD, including Crohn's disease and ulcerative colitis (UC), is known to cause abnormal inflammation in intestinal tissue. UC is accompanied by abdominal pain, bloody stool and diarrhea. Many therapeutic agents, such as sulfasalazine, corticosteroids, immunosuppressive agents, have been used for treating UC. However, those agents have side-effects and temporary effects on UC. The aim of this study was to investigate the effect of herbal medicine on UC and relationship between UC and intestinal bacteria according characteristic of herbal medicine. To determine the effect of herbal medicine on UC, various herbal medicine were chosen within oriental medicine category such as cheongyeol and onyeol medicine. In this study, we found carthami fructus, included in cheongyeol medicine, had stronger effect than onyeol medicine. Also, we determined influence of carthami fructus against lactic acid bacteria. Catthami fructus and lingon berry extracts affected the composition of mice intestinal bacteria in mice fecal. The symptoms of UC could be regulate by using herbal medicine, according to characteristic of herbal medicine. Also, herbal medicine might be change body condition to healthy by controlling intestinal bacteria composition. Herbal medicine characteristic could be a therapeutic agent by revealing relationship between intestinal bacteria and UC.

• International Journal of Advanced Culture Technology
• /
• 제11권4호
• /
• pp.34-41
• /
• 2023

The purpose of this paper is to consider the expansion of non-traditional security threats and the national-level response to the emergence of emerging security threats in ultra-uncertain VUCA situations. As a major research method for better analysis, the theoretical approach was referred to papers published in books and academic journals, and technical and current affairs data were studied through the Internet and literature research. The instability and uncertainty of the international order and security environment in the 21st century brought about a change in the security paradigm. Human security emerged as the protection target of security was expanded to individual humans, and emerging security was emerging as the security area expanded. Emerging security threatsthat have different characteristicsfrom traditionalsecurity threats are expressed in various ways, such as cyber threats, new infectious disease threats, terrorist threats, and abnormal climate threats. First, the policy and strategic response to respond to emerging security threats is integrated national crisis management based on artificial intelligence applying the concept of Foresight. Second, it is to establish network-based national crisis management smart governance. Third, it is to maintain the agile resilience of the concept of Agilience. Fourth, an integrated response system that integrates national power elements and national defense elements should be established.

• Journal of Forest and Environmental Science
• /
• 제39권4호
• /
• pp.213-224
• /
• 2023

As abnormal weather events due to climate change continue to rise, landslide damage is also increasing. Given the substantial time and financial resources required for post-landslide recovery, it becomes imperative to formulate a proactive response plan. In this regard, landslide susceptibility analysis has emerged as a valuable tool for establishing preemptive measures against landslides. Accordingly, this study conducted an annual landslide susceptibility analysis using the history of landslides that occurred over many years in the Jeolla region, and analyzed areas with a high potential for landslides in the Jeolla region. The analysis employed an ensemble model that amalgamated 10 data-based models, aiming to mitigate uncertainties associated with a single-model approach. Furthermore, based on the cumulative data regarding landslide susceptible areas, this research identified regions vulnerable to recurring landslide damage in Jeolla region and proposed specific strategies for utilizing this information at various levels, including local government initiatives, adaptation plan development, and development approval processes. In particular, this study outlined approaches for local government utilization, the determination of adaptation plan types, and considerations for development permits. It is anticipated that this research will serve as a valuable opportunity to underscore the significance of information concerning regions vulnerable to recurring landslide damage.

• Design & Manufacturing
• /
• 제17권3호
• /
• pp.34-40
• /
• 2023

In this study, real-time collection of mold vibration signals during injection molding processes was achieved through IoT devices installed on the mold surface. To analyze changes in the collected vibration signals, injection molding was performed under six different process conditions. Analysis of the mold vibration signals according to process conditions revealed distinct trends and patterns. Based on this result, cosine similarity was applied to compare pattern changes in the mold vibration signals. The similarity in time and acceleration vector space between the collected data was analyzed. The results showed that under identical conditions for all six process settings, the cosine similarity remained around 0.92±0.07. However, when different process conditions were applied, the cosine similarity decreased to the range of 0.47±0.07. Based on these results, a cosine similarity threshold of 0.60~0.70 was established. When applied to the analysis of mold vibration signals, it was possible to determine whether the molding process was stable or whether variations had occurred due to changes in process conditions. This establishes the potential use of cosine similarity based on mold vibration signals in future applications for real-time monitoring of molding process changes and anomaly detection.

• Journal of Genetic Medicine
• /
• 제21권1호
• /
• pp.14-21
• /
• 2024

Infantile nystagmus syndrome (INS) refers to congenital forms of nystagmus that are present at birth or during infancy. This syndrome may be caused by afferent visual system disorders or abnormal development of the ocular motor system. INS is a genetically heterogeneous disorder for which there are more than 100 causative genes. Since applying clinical tests for the differential diagnosis of INS can be challenging in early infancy and children, genetic testings such as next-generation sequencing are becoming more important for achieving accurate diagnoses. An improved understanding of the molecular mechanisms of INS may also lead to the development of gene-based therapies for INS. These advantages of genetic testing have the potential to change the diagnostic paradigm of patients with INS. However, the diagnostic pathway based on genetic testing still has several limitations in terms of the therapeutic effect and methodology. This review summarizes genetic and clinical features of INS, and discusses the promise and pitfalls of genetic testing in INS.

• Molecules and Cells
• /
• 제46권12호
• /
• pp.757-763
• /
• 2023

In this study, we examine whether a change in the protein levels for FOP in Ankyrin repeat and SAM domain-containing protein 1A (ANKS1A)-deficient ependymal cells affects the intraflagellar transport (IFT) protein transport system in the multicilia. Three distinct abnormalities are observed in the multicilia of ANKS1A-deficient ependymal cells. First, there were a greater number of IFT88-positive trains along the cilia from ANKS1A deficiency. The results are similar to each isolated cilium as well. Second, each isolated cilium contains a significant increase in the number of extracellular vesicles (ECVs) due to the lack of ANKS1A. Third, Van Gogh-like 2 (Vangl2), a ciliary membrane protein, is abundantly detected along the cilia and in the ECVs attached to them for ANKS1A-deficient cells. We also use primary ependymal culture systems to obtain the ECVs released from the multicilia. Consequently, we find that ECVs from ANKS1A-deficient cells contain more IFT machinery and Vangl2. These results indicate that ANKS1A deficiency increases the entry of the protein transport machinery into the multicilia and as a result of these abnormal protein transports, excessive ECVs form along the cilia. We conclude that ependymal cells make use of the ECV-based disposal system in order to eliminate excessively transported proteins from basal bodies.

• 한국해안·해양공학회논문집
• /
• 제36권2호
• /
• pp.87-93
• /
• 2024

최근 기후변화 영향에 의한 해수면 상승 및 이상 고파랑 발생, 지속적인 항만·어항개발 등 인공구조물 설치 등으로 연안침식의 피해가 증가하고 있는 추세이다. 본 연구에서는 연안에서 시행되는 개발사업과 침식저감사업 수행 시 진행되는 환경영향평가, 해역이용협의, 재해영향평가, 연안재해 위험평가 제도의 범위와 방법에 대해 분석하여 각각의 문제점을 파악하고, 개선방안을 도출하여 연안침식에 대한 영향을 최소화 할 수 있는 연안침식영 향평가제도의 도입방안을 제안하였다.

• 대한핵의학회지
• /
• 제26권2호
• /
• pp.290-298
• /
• 1992

Although early diagnosis of urinary tract infection is important, the radiologic evaluation is still controversial because of the low sensitivity and the lack of cost-effectiveness. This study was carried out to evaluate the clinical utility of high resolution triple head $^{99m}Tc-DMSA$ SPECT imaging in urinary tract infection. We prospectively performed $^{99m}Tc-DMSA$ planar and SPECT imaging, ultrasound of kidney (US), intravenous pyelography (IVP) and voiding cystourethrography (VCU) in all 60 adult patients with UTI [26 with first episode of acute pyelonephritis (APN), 22 with recurrent APN, and 12 persistent asymptomatic pyuria] and 25 normal persons. To assess reversibility of the renal cortical defect (RCD), $^{99m}Tc-DMSA$ SPECT was repeated 1 to 8 months later in those patients with abnormal initial findings. Overall detection rate of $^{99m}Tc-DMSA$ SPECT imaging was 83% (50/60), but planar, US, IVP and VCU showed abnormal findings in 68%, 28%, 32% and 13%, respectively. 25 out of 27 patients with normal or single RCD were all normal in other radioligic studies. Only two patients showed vesicoureteral reflux (VUR) on VCU (grade I) and mild hydronephrosis on IVP. But, high proportion of those with multiple RCD showed abnormal findings on US (17/33), IVP (18/33), and VCU (7/33): 67% in any of these 3 studies. Especially, 3 out 7 patients with VUR showed multiple RCD on $^{99m}Tc-DMSA$ SPECT without any abnormality on IVP or US. 25 normal persons showed normal findings in all studies except one false positive finding on $^{99m}Tc-DMSA$ SPECT imaging. Follow-up $^{99m}Tc-DMSA$ SPECT was done in 28 patients (13 with single RCD, 15 with multiple RCD). All 13 patients with single RCD showed improvement. Those with multiple RCD presented improvement in 4, no change in 10, and aggravation in 1 on follow-up studies. With these results, we conclude: 1) $^{99m}Tc-DMSA$ SPECT imaging is superior to planar imaging, US, IVP or VCU in detection of renal lesion in urinary tract infection. $^{99m}Tc-DMSA$ SPECT is useful as a initial diagnostic tool in adult patients with urinary tract infection. 2) The multiple RCD on $^{99m}Tc-DMSA$ SPECT represent the high probability of irreversible tissue change and need of extensive urological work-up.