• Proceedings of the Korea Society of Environmental Toocicology Conference
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• 2003.10a
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• pp.23-24
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• 2003

The goal of this study is to develop a biomarker used in monitoring abnormal behaviors of Japanese medaka (Oryzias latipes) as a model organism caused by hazardous chemicals. Japanese medaka was treated by copper and fluoranthene of appropriate sublethal concentrations after starvation for 48 hr. In this study we investigated neural toxicity of copper and fluoranthene in Japanese medaka (Oryzias latipes) along with comparative analysis of corresponding behavioral responses. The untreated individuals showed common behavioral characteristics (i.e., smooth and linear movements). Locomotive activity of the fish was monitored using an image processing and automatic data acquisition system. When treated with copper (100 ppb), the fish showed shaking patterns more frequently. As the concentration of copper increased to 1,000 ppb, activity decreased, and the fish showed an erratic movement. The treated with fluoranthene, however, showed stopping and abrupt change of orientation (100 ppb), and severely reduced locomotive activity and enhanced surfacing activity (1,000 ppb).

• Transactions of the Korean Society of Automotive Engineers
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• v.22 no.3
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• pp.75-80
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• 2014

In previous study, make an attempt to estimate exhaust valve seat and seat-ring wear acceleration factor for engine durability test with measuring and consideration of wear mechanism. But found abnormal initial wear rate in exhaust valve seat-ring. And have to improve exhaust valve seat-ring wear rate for reliability reason, because next GDI/Turbo engine is based on this engine and GDI/Turbo engine have higher combustion pressure and higher thermal load. In this study, Trying to find the cause of abnormal wear factor, improve valve-train durability by change specification & design of parts and verify variant parts for improving durability of valve-train. And then I would like to propose a design guide line of valve-train system in a reliability point of view, besides make a complement of previous study.

• Journal of the Korean Ceramic Society
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• v.23 no.4
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• pp.41-46
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• 1986

When barium titanate was synthesized in solid-solid reaction the abnormal expansion occurred from 90$0^{\circ}C$ to 110$0^{\circ}C$. The equi molecular mixture of $BaCo_3$ and $TiO_2$ was sintered from 90$0^{\circ}C$ to 130$0^{\circ}C$ on the condition of air vacuum and $CO_2$ atomosphere. After that the specimens were tested closely with XDR Dilatometer and SEM The result indicated that: 1, Volume expansion to be synthesized barium titanate in solid-solid reaction was affected by atomosphere sintering. 2. The solid reaction ot fiorm barium titanate in vacuum atomosphere occurred faster than that in air atomosphere. In vacuum atomosphere the maxium volume expansion was about 30% at 90$0^{\circ}C$ for 2hrs, 3. The solid reaction to form barium titanate in 4CO_2$ atomosphere occurred slower than that in air atomosphere. In $CO_2$ atomosphere the maximum volume expansion was 13% at 100$0^{\circ}C$ for 2 hrs. 4. According to the result of x-ray the expanison was caused by the reaction to form $BaTiO_3$ and change $Ba_2TiO_4$ into 4BaTiO_3$.

• Journal of the Korea Society of Computer and Information
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• v.23 no.10
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• pp.65-72
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• 2018

In this paper, we used LSTM as a method to detect abnormal behavior of motors. We fixed the high layout size to 1 and changed the range of the input values and the neural network structure to see what change in power consumption prediction. Now, as the fourth industrial revolution era, smart factories are attracting attention. All the physical actions of smart factories are done using motors. Continuous monitoring of motor malfunctions helps to detect malfunctions and efficient operation. However, it is difficult to acquire the power consumption constantly due to the influence of the noise. We have experimented with a simple experimental environment, a method of predicting similarity to input data by adjusting the range of the input data or by changing the neural network structure.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.17 no.2
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• pp.59-71
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• 2004

Melanin pigmentation has an essential role in protecting human skin against the damaging effects of ultra violet radiation, infection, environmental factor, etc. However abnormal melanin pigmentation can directly cause a number of congenital and acquired pigmentary skin disease. This study conducted to evaluate the effects of various partition extracts of Codonopsis lanceolata on the melanogenesis in the B 16 melanoma cells. The cells were treated for 3 days with various partition extracts of Codonopsis lanceolata. While treatment with the BuOH partition extract of Codonopsis lanceolata increased significantly the tyrosinase activity and melanin content, the n-Hexane or ethyl acetate partition extract dose-dependently suppressed them compared with untreated control. But ethyl acetate partition significantly decreased the cell viability. The H2O partiton extract at various concentrations did not exhibit any significant change on the melanogenesis. These results indicate that treatment with the n-Hexane partition extract inhibits the melanogenesis in B16 melanoma cells, and raise the possibility that this extract may be effective in the abnormal melanin pigmentation as well as the whitening agent for the skin.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.25 no.4
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• pp.300-311
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• 2022

Purpose: Dysphagia, vomiting and feeding difficulties are common symptoms, with which children present. Esophageal function testing with high resolution manometry can help in diagnosing and treating these patients. We aim to access the clinical utility of high-resolution manometry of esophagus in symptomatic pediatric patients. Methods: A retrospective chart review was done on all symptomatic patients who underwent esophageal high-resolution manometry between 2010 and 2019 at Sydney Children's Hospital, Australia. Manometry results were categorized based on Chicago classification. Demographic data, indication of procedure, manometric findings, and details of treatment changes were obtained and analyzed. Results: There were 62 patients with median age of 10 years (9 months-18 years). The main indication for the procedure was dysphagia (56%). Thirty-two percent of patients had a co-morbid condition, with esophageal atresia accounting for 16%. The majority (77%) of patients had abnormal manometry which included, ineffective esophageal motility in 45.2%. In esophageal atresia cohort, esophageal pressurization was seen in 50%, aperistalsis in 40% and 10% with prior fundoplication had esophago-gastric junction obstruction. Patients with esophago-gastric junction obstruction or achalasia were treated by either pneumatic dilation or Heller's myotomy. Patients with ineffective esophageal motility and rumination were treated with a trial of prokinetics/dietary texture modification and diaphragmatic breathing. Conclusion: Esophageal high-resolution manometry has a role in the evaluation of symptomatic pediatric patients. The majority of our patients had abnormal results which led to change in treatments, with either medication, surgery and/or feeding modification with resultant improvement in symptoms.

• Journal of the Korean Society of Hazard Mitigation
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• v.9 no.4
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• pp.115-127
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• 2009

Recently, Natural disasters are increasing the damage according to the influence of the abnormal climate and climate change. This study analyzed change characteristic of Design Rainfall according to the different data periods. First, 14 observatories were selected at Meteorological Administration. Second, frequency analysis carried out 5 cases by different data periods. At the results of the frequency analysis, the design rainfall could confirm the increase in most areas of Korea. Also, the change and trend analysis carried out for characteristic analysis by design rainfall and observed rainfall. The change and trend analysis of observed annual maximum rainfall did not appeared, but the change and trend analysis of design rainfall significantly appeared using statistic methods. The result of the change and trend analysis, design rainfall increased in most areas of Korea. Although, it could be the necessity for reestimating defense ability of flood, existing river systems, and new establishment of structure about the change characteristic.

• Journal of Climate Change Research
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• v.7 no.3
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• pp.315-324
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• 2016

The relevant ministries, including the Ministry of Environment in Korea, provided Post-2020 Long-term Mitigation Target and Implementation Plan. The plan consisted of four Business As Usual (BAU) reduction levels by 14.7%, 19.2%, 25.7%, and 31.3% until 2030. The Korean government finalized the mitigation target of 37%. But all the initial alternatives were below the goal, 30% from BAU, that has been promised to the international community as well as set out in the Framework Act on Low Carbon Green Growth. In order to achieve a specific goal, performance management should pursue "Justify doing the right things." Otherwise, performance management would not work properly. According to Kingdon's Policy Stream Framework, abnormal alternatives are difficult to be presented as scenarios because alternative building should focus on the role of the need to adhere to the basic principles and professionals. Such a result is possible only when the policy actors does not balance themselves. Performance management statistics has been analyzed by 6 years CCPI data since 2011, taking into account the impact after enactment. This study also has been complemented by a variety of sources, including the media, documents, and artifacts during the period. As a result, raising awareness about climate change was analyzed as one of the solutions because the climate change issue affects the normal performance management throughout the life of the people to stay linked to the environment.

• Journal of Korean Foot and Ankle Society
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• v.6 no.2
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• pp.195-200
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• 2002

Purpose: To investigate the MRI and arthroscopic findings of osteochondral lesion of the talus which looked normal on plane radiography. Materials and methods: We investigated the MRI and arthroscopic findings of seven osteochondral lesions in which there were no abnormal finding on plane radiography and no cystic changes on MRI. Average age was 31 years(range, 19-43 years). Arthroscopic findings were classified according to the Ferkel's criteria. Results: History of injury was reported in all cases and the average duration from injury to presentation was 4 years and 4 months. Low signal change in T1WI was found in 6 of 7 lesions, no signal change in 1 case. Low signal change in T2WI was found in 4, no signal change in 3. 6 STIR images were obtained. High signal change was found in 3, no signal change in 2 and intermediate signal change was in 1. Arthroscopic grading was A in 1, C in 1, D in 2 , E in 1 and F in 2. We could not find any correlation between the findings on MRI and arthroscopic examination. Conclusion: We suggest arthroscopic examination is needed for accurate diagnosis of the osteochondral lesions of the talus which looked normal on plane radiography, because they have various MRl findings and high likelihood of existence of unstable cartilage lesions.

• Imaging Science in Dentistry
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• v.31 no.3
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• pp.159-164
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• 2001

Purpose: To evaluate the osseous changes of TMJ in internal derangement and osteoarthritis patients using MRI. Materials and Methods: MR images of 111 TMJs in 64 patients were analyzed to evaluate the osseous changes, 111 TMJs were divided into 6 groups according to the radiologic Stages by Schellhas and Wilkes. On MR images, we evaluate the osseous changes of articular eminence and condylar head. Results: The most frequent Stage in internal derangement of TMJ was Stage I. And 28 joints (25.2%) revealed osteoarthritis with internal derangement. When osseous change of articular eminence and condylar head occur, flattening was the most common osseous change. Sclerosis was observed in all Stages and osteophytosis of condylar head was observed in Stage II (1.8%) and III (0.9%). Out of 28 joints with osteoarthritis, 6 joints (21.4%) showed joint effusion. Conclusion: MR image revealed abnormal configuration of disk, but the detection of minimal osseous change was subtle.