• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2008.03a
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• pp.566-569
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• 2008

Recently, the biolistic process is emerging as an effective needle-free drug delivery technique to transfer adequate concentrations of pharmacologic agents to soft living tissues with minimum side effects. We have started developing an effective method for delivering drug coated particles using laser ablation. A thin metal foil with deposited micro-particles on one side is irradiated with laser beam on the opposite side so that a shock wave is generated. This shock wave travels through the foil and is reflected, which causes and instantaneous deformation of the foil. Due to such a sudden deformation, the micro-particles are ejected at a very high speed. Here we present the experimental results of direct and confined laser ablation, which correspond to the initial stage of the whole experiment.

• Perinatology
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• v.29 no.4
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• pp.180-184
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• 2018

In assisted reproductive techniques, monozygotic twinning is not influenced by the trial of reducing the number of embryos transferred. We present extremely rare case of monochorionic triamniotic triplet pregnancy following in vitro fertilization and two-embryo transfer. During the first trimester, the crucial ultrasound findings of monochorionic triamniotic triplet pregnancy are three distinct amniotic sacs forming a triangle or ipsilon zone within a single chorionic cavity. After prudential counseling about the potential risk of a monochorionic triamniotic triplet pregnancy with the patient, selective reduction of two fetuses via radiofrequency ablation was performed. We report a case of selective reduction for monochorionic triamniotic triplet pregnancy using radiofrequency ablation at 12 weeks' gestation and obstetric progression after radiofrequency ablation was uneventful until 20 weeks' gestation.

• Journal of the Korean Society of Propulsion Engineers
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• v.3 no.2
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• pp.37-47
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• 1999

This paper describes the thermal analysis which can calculate the ablation depth and temperature distribution of the rocket nozzle liner allowing geometry change caused by the ablation of nozzle liner. In this analysis, Zvyagin's model is used for surface ablation and Yaroslavtseva's model for in-depth pyrolysis. A deforming finite-element grid is used to account for external-boundary movement due to the erosion of thermal liner. The accuracy of the present numerical method is evaluated with a rocket nozzle liner and the numerical solutions are favorably agreed with experimental data. The temporal variations of temperature and ablation depth at the thermal liner of another rocket nozzle are numerically simulated and the results are discussed. Special emphasis is given to the effects of kinetic constants for carbon-carbon and carbon-phenolic composites on the ablation depth of thermal liner.

• Clinical and Experimental Pediatrics
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• v.60 no.12
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• pp.390-394
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• 2017

Purpose: Atrioventricular nodal reentry tachycardia (AVNRT) is less common in pediatric patients than in adult patients. Thus, data for pediatric AVNRT patients are insufficient. Hence, we aimed to analyze the patient characteristics, treatment, and any recurrences in pediatric AVNRT patients. Methods: We reviewed the records of 50 pediatric AVNRT patients who had undergone radiofrequency catheter ablation (RFCA) between January 1998 and December 2016 at a single regional center. The patients were aged ${\leq}18years$. Results: Among 190 pediatric patients who underwent RFCA for tachyarrhythmia, 50 (26.3%; mean age, $13.4{\pm}2.6years$) were diagnosed as having AVNRT by electrophysiological study. Twenty-five patients (25 of 50, 50%) were male. Twenty patients (20 of 50, 40%) used beta-blockers before RFCA. All patients had no structural heart disease except 1 patient with valvular aortic stenosis and coarctation of the aorta. RFCA was performed using the anatomic approach under fluoroscopic guidance. The most common successfully ablated region was the midseptal region (25 of 50, 50%). Slow pathway (SP) ablation and SP modulation were performed in 43 and 6 patients, respectively. Complication occurred in 1 patient with complete atrioventricular block. During follow-up, 6 patients had recurrence of supraventricular tachycardia, as confirmed by electrocardiography. Among them, 5 underwent successful ablation at the first procedure. In 1 patient, induction failed during the first procedure. Conclusion: RFCA is safe and effective in pediatric AVNRT patients. However, further research is needed for establishing the endpoints of ablation in pediatric AVNRT patients and for identifying risk factors by evaluating data on AVNRT recurrence after RFCA.

• Proceedings of the Korean Vacuum Society Conference
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• 2016.02a
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• pp.200.2-200.2
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• 2016

Carbon-based materials have been known as ablative material and have been used for thermal protection systems. Ablation is an erosive phenomenon that results in thermochemical and thermomechanical changes on materials. Ablation resistance is one of the key properties that determines performance and life-time of the thermal protection material under ablative conditions. In this study, ablation properties of graphite, 3-dimensional (C/C) composites (needle-punched type and rod type) were investigated byusing a plasma wind tunnel which produce a supersonic plasma flow from a segmented arc heater with the power level of 0.4 MW. The mass losses and surface roughness changes which contain main result of the ablation are measured. A morphological analysis ofthe carbon-based materials, before and after the ablation test, are performed through field emission scanning electron microscopy (FE-SEM) and non-contact 3D surface measuring system. Electronic balance and a portable surface roughness tester were used for evaluation of the recession and mass loss of the test samples.

• Journal of the Korean Society for Precision Engineering
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• v.21 no.12
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• pp.13-20
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• 2004

Manufacturing process for the microfluidic device can include such sequential steps as master fabrication, electroforming, and injection molding. The laser ablation using masks has been applied to the fabrication of channels in microfluidic devices. In this study, manufacturing of polymer master and mold insert for micro injection molding was investigated. Ablation of PET (polyethylene terephthalate) by the excimer laser radiation could be used successfully to make three dimensional master fur nickel mold insert. The mechanism fur ablative decomposition of PET with KrF excimer laser $({\lambda}: 248 nm, pulse duration: 5 ns)$ was explained by photochemical process, while ablation mechanism of PMMA (polymethyl methacrylate) is dominated by photothermal process, the .eaction between PC (polycarbonate) and KrF excimer laser beam generate too much su.face debris. Thus, PET was adopted in polymer master for nickel mold insert. Nickel electroforming using laser ablated PET master was preferable for replication method. Finally, it was shown that excimer laser ablation can substitute for X-ray lithography of LIGA process in microstructuring.

• Journal of Korean Ophthalmic Optics Society
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• v.12 no.3
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• pp.121-124
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• 2007

Ablation depth of cornea in refractive keratectomy was calculated by Munnerlyn formula. The calculations were preformed for various optical diameter (4 mm~8 mm) and various amount of corrections (-1 Dptr ~ -12 Dptr). The results to be compared with the Munnerlyn approximated formula had little effect within lower corrections, but in higher corrections > 6 Dptr can be occurred the error of 1 Dptr. Although ablation depth were evaluated, the results were only calculated by mathematical model of geometric assumptions. Because ablation depth can vary with operation conditions, the correction factor should be considered not only ablation depth by Munnerlyn formula but also surgeon-specific factor.

• Carbon letters
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• v.9 no.4
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• pp.316-323
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• 2008

The factors that influence ablation resistance in fiber composites are properties of the reinforced fiber and matrix, plugging quantity of fiber, geometrical arrangement, crack, pore size, and their distributions. To examine ablation resistance according to distribution of crack and pore size that exist in carbon/carbon composites, this study produced various sizes of unit cells of preforms. They were densified using high pressure impregnation and carbonization process. Reinforced fiber is PAN based carbon fiber and composites were heat-treated up to $2800^{\circ}C$. The finally acquired density of carbon/carbon composites reached more than $1.932\;g/cm^3$. The ablation test was performed by a solid propellant rocket engine. The erosion rate of samples is below 0.0286 mm/s. In conclusion, in terms of ablation properties, the higher degree of graphitization is, the more fibers that are arranged vertically to the direction of combustion flame are, and the less interface between reinforced fiber bundle and matrix is, the better ablation resistance is shown.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2006.05a
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• pp.657-658
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• 2006

Although there are many numerical models to simulate fs laser ablation of metals, no model can analyze the ablation phenomena over a wide range of fluence. In this work, a numerical code for simulating the fs laser ablation phenomena of metals has been developed. The two temperature model is employed to predict the ablation rate and the crater shape of metals using phase explosion mechanism in the relatively high fluence regime. Also, the ultrashort thermoelastic model is used for the low fluence regime to account for spallation of the sample by high strain rate. It has been demonstrated that the thermoelastic stress generated within the sample can exceed the yield stress of the material even near the threshold fluence. Numerical computation results are compared with the experiment for Cu and Ni and show good agreement. Discussions are made on the hydrodynamic model considering phase change and hydrodynamic flow.

• Laser Solutions
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• v.18 no.4
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• pp.17-22
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• 2015

In this paper, ablation rate of $Al_2O_3$ ceramics by femtosecond laser fluence is derived with experimental method. The automatic three axis linear stage makes laser optics to move with high spatial resolution. With 10 times objective lens, minimal pattern width of $Al_2O_3$ is measured in the focal plane. Ablated surface area is shown as linear tendency increasing number of machining times with various laser power conditions. Machining times is most sensitive condition to control $Al_2O_3$ pattern width. Also, the linear increment of pattern width with laser power change is investigated. In high machining speed, the ablation volume rate is more linear with fluence because pulse overlap is minimized in this condition. Thermal effect to surrounding medium can be minimized and clean laser process without melting zone is possible in high machining speed. Ablation volume rate decelerates as increasing machining times and multiple machining times should be considered to achieve proper ablation width and depth.