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A Comprehensive Study of SARS-CoV-2: From 2019-nCoV to COVID-19 Outbreak

  • Waris, Abdul;Ali, Muhammad;Khan, Atta Ullah;Ali, Asmat;Baset, Abdul
    • Microbiology and Biotechnology Letters
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    • v.48 no.3
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    • pp.252-266
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    • 2020
  • The coronavirus disease 2019 (COVID-19) is a highly contagious pneumonia that has spread throughout the world. It is caused by a novel, single stranded RNA virus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Genetic analysis revealed that, phylogenetically, the SARS-CoV-2 is related to severe acute respiratory syndrome-like viruses seen in bats. Because of this, bats are considered as a possible primary reservoir. The World Health Organization has declared the COVID-19 outbreak as a pandemic. As of May 27, 2020, more than 5,406,282 confirmed cases, and 343,562 confirmed deaths have been reported worldwide. Currently, there are no approved vaccines or antiviral drugs available against COVID-19. Newly developed vaccines are in the first stage of clinical trials, and it may take a few months to a few years for their commercialization. At present, remdesivir and chloroquine are the promising drugs for treating COVID-19 patients. In this review, we summarize the diversity, genetic variations, primary reservoirs, epidemiology, clinical manifestations, pathogenesis, diagnosis, treatment strategies, and future prospects with respect to controlling the spread of COVID-19.

Thermal and Mechanical Properties of Waste Ground Nut-shell Reinforced Polyester Composites

  • Prabhakar, M.N.;Shah, Atta ur rehman;Song, Jung-Il
    • Composites Research
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    • v.28 no.3
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    • pp.118-123
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    • 2015
  • In the current study explain about the bio-based composites made by groundnut shell as reinforcement with polyester resin matrix. Groundnut shell is an abundantly available natural waste byproduct and poly ester resin is widely used to fabricate of composites for good balance of mechanical properties because it is relatively low price and ease of handling. Evaluate the mechanical properties of manufactured groundnut shell/polyester composites by varying the amounts (wt %) of groundnut shell. Particulate shell reinforced polyester composites incorporating varying amounts of groundnut shell (5, 10, 15 and 20%) were characterized for their tensile strength, flexural strength, and impact strength. The mechanical properties improved with increasing particle loading up to 15% and decreased thereafter. Increasing in strength with increased particle shell loading was attributed to increase in surface area which enhanced load transfer between the polyester matrix and ground shall particulates. Scanning electron microscopic studies have been carried out to study the morphology of the composite. Thermal studies and water absorption properties of the composites also studied in this paper.

Development and Characterization of Oyster Shell Powder Filled Polypropylene Composite

  • Shah, Atta ur Rehman;Prabhakar, M.N.;Lee, Dong-Woo;Kim, Byung-Sun;Song, Jung Il
    • Composites Research
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    • v.27 no.5
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    • pp.201-206
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    • 2014
  • Utilizing waste materials in making useful products is a globally increasing trend. This can reduce the cost and environmental issues. In this study, oyster shell powder (OSP) is reinforced as a filler in polypropylene (PP) matrix to make a new composite. The purpose is to improve fire retardant properties of PP as a result of OSP reinforcement. Mechanical, fire retardant and water absorption properties of the new composite have been studied in this research. Concentration of OSP reinforcement in PP has been varied by wt% and its effect on the above mentioned properties has been observed. SEM (scanning electron microscopy) images of tensile and bending fractured surfaces have been taken to observe the failure mechanism during mechanical tests. An increase in the fire retardancy has been observed as a result of the OSP reinforcement while tensile strength decreased. Stiffness also increased with the addition of OSP in PP.

Recent Advances in Synthetic, Industrial and Biological Applications of Violacein and Its Heterologous Production

  • Ahmed, Aqsa;Ahmad, Abdullah;Li, Renhan;AL-Ansi, Waleed;Fatima, Momal;Mushtaq, Bilal Sajid;Basharat, Samra;Li, Ye;Bai, Zhonghu
    • Journal of Microbiology and Biotechnology
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    • v.31 no.11
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    • pp.1465-1480
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    • 2021
  • Violacein, a purple pigment first isolated from a gram-negative coccobacillus Chromobacterium violaceum, has gained extensive research interest in recent years due to its huge potential in the pharmaceutic area and industry. In this review, we summarize the latest research advances concerning this pigment, which include (1) fundamental studies of its biosynthetic pathway, (2) production of violacein by native producers, apart from C. violaceum, (3) metabolic engineering for improved production in heterologous hosts such as Escherichia coli, Citrobacter freundii, Corynebacterium glutamicum, and Yarrowia lipolytica, (4) biological/pharmaceutical and industrial properties, (5) and applications in synthetic biology. Due to the intrinsic properties of violacein and the intermediates during its biosynthesis, the prospective research has huge potential to move this pigment into real clinical and industrial applications.

Applications of 5G and 6G in Smart Health Services

  • Al-Jawad, Fatimah;Alessa, Raghad;Alhammad, Sukainah;Ali, Batoola;Al-Qanbar, Majd;Rahman, Atta-ur
    • International Journal of Computer Science & Network Security
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    • v.22 no.3
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    • pp.173-182
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    • 2022
  • Healthcare organizations are overwhelmingly embracing smart value-based care strategies, which focuses on providing superior treatment at a significantly lower cost and quality of service (QoS). For these purposes, fifth generation (5G) of mobile service provides an innumerable improvement that clearly outperforms previous generations e.g., 3G and 4G. However, as with most advancements, 5G is projected to introduce new challenges, prompting the community to think about what comes next. This research was conducted to examine the most recent smart 5G technology applications and the solutions they provide to the healthcare industry. Finally, the paper discusses how the upcoming 6G technology has the potential to transform the future of healthcare sector even beyond the current 5G systems.

The Impact of Supervisory Communication Apprehension on Subordinates' Job Performance: An Empirical Study in Pakistan

  • ASAD, Muhammad;ZAFAR, Mueen Aizaz;SAJJAD, Aymen
    • The Journal of Asian Finance, Economics and Business
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    • v.9 no.2
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    • pp.437-448
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    • 2022
  • The impact of supervisory communication apprehension (SCA) on subordinates' job performance was investigated in this study. We also examined the impact of task-related uncertainty in mediating the relationship between SCA and subordinate work performance, as well as the role of information-seeking behavior in moderating the relationship between task-related uncertainty and subordinate job performance. A sample of subordinates and their supervisors from public and private sector enterprises in Pakistan were used in the study. The concept of communication apprehension is not limited to a single organization or industry, and the conditions suggest that apprehensive supervisors are likely to exist in different organizations and industries in Pakistan, including banks, telecommunications, and development sector organizations. Company directors and leaders of human resources departments were contacted to reach out to possible respondents. SmartPLS software was used to evaluate the data using a structural equation modeling technique which is commonly used in explanatory studies (Atta et al., 2021). We found evidence to support ideas predicting the association between SCA and subordinate job performance, as well as the mediating role of task-related ambiguity in the relationship. Furthermore, the findings show that information-seeking activity has a moderating effect on the link between task-related ambiguity and subordinate job performance. This is one of the first studies to look at major mediating and moderating mechanisms in the link between SCA and subordinate job performance.

Quality Evaluation of e-Government Services: A Systematic Literature Sudan as a Case Study

  • Elmouez Samir Abd Elhameed Mohamed;Amgad Atta Abedelmageed Mohammed
    • International Journal of Computer Science & Network Security
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    • v.23 no.5
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    • pp.95-108
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    • 2023
  • The technological revolution, also referred to as the Fourth Industrial Revolution, it embraced by government should transform the way governments serve their citizens. The growth of broadband in Africa is leapfrogging its technological development. And thus, many African governments will soon be able to offer quality e-Government services to their citizens. These technologically driven governments will be able to provide decision-makers with timeous information to make judgments that could influence policies. Proponents of e-Government believe that in the digital age, governments can use this information to reduce corruption and increase, accountability, transparency, efficiency, and public participation. e-Government service quality should ensure customer satisfaction. Although many studies have examined the role of e-Government and the quality of its services, few studies have examined the quality of e-Government services in terms of both supply and demand. This paper examines and reviews the academic-state-of-the-art on the factors that affect the quality of e-Government services from both perspectives. Utilizing both qualitative and quantitative methods for data gathering and analysis, a mixed methods research methodology was used.

A Proposed Model for Supply Chain using Blockchain Framework

  • Zenab AlSadeq;Haya Alubaidan;Alanoud Aldweesh;Atta-ur-Rahman ;Tahir Iqbal
    • International Journal of Computer Science & Network Security
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    • v.23 no.6
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    • pp.91-98
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    • 2023
  • The rapid increase in the use of new technology known as 'blockchain technologies' has addressed many challenges in different areas and provided benefits to users, in this paper we discuss the field of supply chains, improve confidence and transparency between participants and stakeholders significantly also in this paper we Compare between different blockchain frameworks focusing on most popular frameworks. Moreover, we proposed a model in the supply chain using a blockchain framework, the proposed supply chain model included many different resources that help to exchange information over the network. The proposed model also includes smart contracts that maintain all rules for transactions. using blockchain technology information such as transaction details, time and money are recorded and stored within the system from the beginning of the transaction entry.

Design of intelligent computing networks for a two-phase fluid flow with dusty particles hanging above a stretched cylinder

  • Tayyab Zamir;Farooq Ahmed Shah;Muhammad Shoaib;Atta Ullah
    • Computers and Concrete
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    • v.32 no.4
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    • pp.399-410
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    • 2023
  • This study proposes a novel use of backpropagated Levenberg-Marquardt neural networks based on computational intelligence heuristics to comprehend the examination of hybrid nanoparticles on the flow of dusty liquid via stretched cylinder. A two-phase model is employed in the present work to describe the fluid flow. The use of desulphated nanoparticles of silver and molybdenum suspended in water as base fluid. The mathematical model represented in terms of partial differential equations, Implementing similarity transformationsis model is converted to ordinary differential equations for the analysis . By adjusting the particle mass concentration and curvature parameter, a unique technique is utilized to generate a dataset for the proposed Levenberg-Marquardt neural networks in various nanoparticle circumstances on the flow of dusty liquid via stretched cylinder. The intelligent solver Levenberg-Marquardt neural networks is trained, tested and verified to identify the nanoparticles on the flow of dusty liquid solution for various situations. The Levenberg-Marquardt neural networks approach is applied for the solution of the hybrid nanoparticles on the flow of dusty liquid via stretched cylinder model. It is validated by comparison with the standard solution, regression analysis, histograms, and absolute error analysis. Strong agreement between proposed results and reference solutions as well as accuracy provide an evidence of the framework's validity.

Etiopathogenesis of sacroiliitis: implications for assessment and management

  • Baronio, Manuela;Sadia, Hajra;Paolacci, Stefano;Prestamburgo, Domenico;Miotti, Danilo;Guardamagna, Vittorio A.;Natalini, Giuseppe;Bertelli, Matteo
    • The Korean Journal of Pain
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    • v.33 no.4
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    • pp.294-304
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    • 2020
  • The sacroiliac joints connect the base of the sacrum to the ilium. When inflamed, they are suspected to cause low back pain. Inflammation of the sacroiliac joints is called sacroiliitis. The severity of the pain varies and depends on the degree of inflammation. Sacroiliitis is a hallmark of seronegative spondyloarthropathies. The presence or absence of chronic sacroiliitis is an important clue in the diagnosis of low back pain. This article aims to provide a concise overview of the anatomy, physiology, and molecular biology of sacroiliitis to aid clinicians in the assessment and management of sacroiliitis. For this narrative review, we evaluated articles in English published before August 2019 in PubMed. Then, we selected articles related to the painful manifestations of the sacroiliac joint. From the retrieved articles, we found that chronic sacroiliitis may be caused by various forms of spondyloarthritis, such as ankylosing spondyloarthritis. Sacroiliitis can also be associated with inflammatory bowel disease, Crohn's disease, gout, tuberculosis, brucellosis, and osteoarthritis, indicating common underlying etiological factors. The pathophysiology of sacroiliitis is complex and may involve internal, environmental, immunological, and genetic factors. Finally, genetic factors may also play a central role in progression of the disease. Knowing the genetic pre-disposition for sacroiliitis can be useful for diagnosis and for formulating treatment regimens, and may lead to a substantial reduction in disease severity and duration and to improved patient performance.