• Title/Summary/Keyword: ASK-1

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Extract of Broussometia kazinoki Induces Apoptosis Through the Mitochondria/Caspase Pathway in A549 Lung Cancer Cells (A549세포에서 닥나무 추출물의 미토콘드리아/Caspase 경로를 통한 Apoptosis 유도작용)

  • Kim, Tae Hyeon;Kim, Dan Hee;Mun, Yeun Ja;Lim, Kyu Sang;Woo, Won Hong
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.30 no.3
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    • pp.150-156
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    • 2016
  • Extract of Broussometia kazinoki Rhizodermatis has been traditionally used for geopoong, diuresis, hwalhyeol. In the present study, the apoptotic effect of methanol extract of Broussometia kazinoki (MBK) were investigated. Cell viability of A549 cells was measured by MTT assay. Apoptosis-related protein and MAPK protein levels were measured by Western blot. Chromatin condensation of A549 cells was stained with DAPI. MBK inhibited cell proliferation of A549 cell. Based on DAPI staining, MBK-treated cells manifested nuclear shrinkage, condensation and fragmentation. Treatment of A549 cells with MBK resulted in activation of the caspase-3, -8, -9 and cleavage of poly ADP-ribose polymerase (PARP). In the upstream, MBK increased the expressions Bax and Bak, decreased the expression of Bcl-2, and augmented the Bax/Bcl-2 ratio. MBK-induced apoptosis was accompanied by sustained phosphorylation of JNK, p38 MAPK and apoptosis signal-regulating kinase (ASK)-1. These results suggest that MBK induced apoptosis in A549 cells through Bcl-2 family protein-mediated mitochondria/caspase-3 dependent pathway. In addition, MBK increased the activation of ASK-1, which are critical upsteam signals for JNK/p38 MAPK activation in A549 cancer cells.

OFDM Star Network Based on Carrier Distribution (캐리어 분배에 의한 OFDM 스타망에 관한 고찰)

  • 채창준
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.21 no.1
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    • pp.281-290
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    • 1996
  • In this paper we suggest an OFDM star network based on carrier distribution and homodyne detection in which all optical carriers generated and stabilized in a specific node are distributed to each node. We studied ASK and PSK modulation schemes and calculated rspective SNRs and BERs for this network. We also discussed on the optical power requirement on the light sources for 200 Mb/s transmission speed. As a result, we found tht ASK and PSK respectively require 13 dBm and 10 dBm for 32 nodes and the nmber of nodes can be expanded to 73 with only 0 dBm of power and minimum insertion losses of components. The proposed network is more reliable than the conventional ones due to the centralized carrier maintenance andthe network is suitable for the adverse environment of the nodes.

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Data Rate Enhancement by using QPSK on Physical Layer of Korea Dedicated Short Range Communications (QPSK 변조를 통한 DSRC Data Rate 향상 방안)

  • Park, Jin-Young;Kim, Han-Kyoung;Jeon, Wang-Won
    • 한국정보통신설비학회:학술대회논문집
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    • 2007.08a
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    • pp.50-54
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    • 2007
  • 현재 국내에서 ITS(Intelligent Transport Systems) 통신방식으로 이 용되고 있는 DSRC 방식은 TTA(한국정보통신기술협회)의 기술표준으로서 대전시,전주시에 적용되어 BIS(Bus Information Service)에 이용되고 있고,최근 고속도로 ETCS(Electronic Toll Collection System)가 DSRC방식으로 전국고속도로 Tollgate 에서 2007년 연말에 개통될 예정이다. DSRC 방식은 2000년에 TTA(한국정보통신기술협회)에서 기술표준이 제정되어 현재 1Mbps 의 Data 용량을 가진다. DSRC 방식의 물리링크 변조방식은 ASK(Amplitude Shift Keying)로 ITS 확장 서비스 적용을 위해 변조방식을 QPSK(Quadrature Phase Shift Keying )로 개선하게 되면 이론적으로 4배의 Data Rate 향상이 이루어진다. 물리적인 RF 변조방식을 ASK에서 QPSK로 바꿔 간단히 Data Rate을 개선하게 되면 회로구현의 경제성이 향상되어 DSRC 응용 서비스가 활성화 될 것이다.

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Implementation of Binary Search Algorithm for RFID system and A Study of Performance with RFID system (RFID용 이진 검색 알고리즘의 구현 및 시스템 성능에 관한 연구)

  • Cho, Kyung-Chul;Son, Sung-Chan;Kim, Young-Cheol
    • 한국정보통신설비학회:학술대회논문집
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    • 2005.08a
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    • pp.285-289
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    • 2005
  • In recent years, RFID is widely used in industrial applications including factory, material flow, logistics and defense areas. In this paper, we developed a RFID baseband system with ASK modulation and convolutional channel code. A commercial ASK RF module is used its frequency range in $350{\sim}351$MHz and power is 10mW and the convolution code is constraint length k=3 and rate R=1/2 The performance is measured implemented the binary search algorithm as anti-collision method and we show the wave shapes whit collision occurrence.

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A Study on the Allocation Plan of 57~64GHz Millimeter Wave (57~64GHz 밀리미터파 대역 분배 방안 연구)

  • Seo Ji-Young;Ahn Jun-Oh
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.17 no.9 s.112
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    • pp.874-882
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    • 2006
  • We surveyed the international and national spectrum & technical standardization trends of extremely adaptive frequency bands $57\sim64GHz$ that can provide 1 Gbps bit-rate ultra broadband service in above 30 GHz millimeter waves, and analyzed service scenarios and the characteristics of these bands, As a result of these analysises, 1 Gbps ASK channel bandwidth needs 2.5 GHz and total bandwidth calculated 7 GHz for dual FDD. finally, we proposed the nationally suitable allocation plan of millimeter wave bands $57\sim64GHz$.

Comprehensive Performance Analysis and Comparison of various Digital Communication Systems in an Multipath Fading Channel with additive Mixture of Gaussian and Impulsive Noise [Part-1] (가우스성 잡음과 임펄스성 잡음이 혼재하는 다중전파 페이딩 전송로상에서의 제반 디지털 통신 시스템 특성의 종합분석 및 비교에 관한 연구(제 1 부))

  • 김현철;고봉진;공병옥;조성준
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.14 no.3
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    • pp.263-279
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    • 1989
  • In part-1 of this paper, the error rate equations of digitally modulated signals transmitted though the Gaussian/Impulsive noise channel have been derived. Using the derived equations for the error probabilities of ASK, QAM, CPSK, DPSK, FSK and MSK signals, the error rate performances of digital modulation systems have been evaluated and represented in the figures as the functions of carrier-to-noise power ratio(CNR), impulsive index, and the ration of Gaussian noise power component to impulsive noise power component. The results are shown in graphs to known how much impulsive noise effects on digital signals than Gaussian noise.

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A new Robust Wavelet Shift Keying System Using Scaling and Wavelet Functions (스케일링 함수와 웨이브릿을 이용한 잡음에 강인한 새로운 웨이브릿 편이 변조 시스템)

  • Jeong, Tae-Il
    • Journal of the Institute of Convergence Signal Processing
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    • v.9 no.2
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    • pp.98-103
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    • 2008
  • There are the frequency shift keying(FSK), phase shift keying(PSK) and amplitude shift keying(ASK) in the conventional digital communications method. In this paper, We proposed a new robust wavelet shift keying system using scaling and wavelet function in the digital communication. Wavelet Transform consist of a low frequency and high frequency coefficient. When the input signal is one, if it finds the impulse response, the signal is separated from the scaling and wavelet function. The binary data is encoded by modulator which assigned the scaling function to 1(one), and wavelet to zero(0). It was demonstrated by experiment that the proposed algorithm can be a robust noise.

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