• Proceedings of the SCSK Conference
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• 2003.09b
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• pp.218-218
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• 2003

Recently we showed the prototype portable device for the determination of human skin moisture by using near infrared spectroscopy. In order to optimize the acquiring condition of NIR spectrum of skin and control the target information of water depending the site such as epidermis and dermis, skin depth profiling was investigated changing the distance between illuminations and receiving of radiation in the terminal of fiber probe. The colleted light information could be controlled by changing the distance of the fiber optic probes. It was confirmed that the longer distance we used, the deeper site from the skin surface we could get information from in this study. Four kinds of probes with distances such as 0.03 mm, 0.1 mm, 0.5 mm, and 1.0 mm were used. In addition, the gap size from 0.3 mm to 3.0 mm was studied to control the intensity of water absorbance effectively and to avoid saturation of water absorption. We also investigated the reference materials depending the reflectance ratio for water absorption not to be saturated because of the strong absorptivity of water. Furthermore, spectroscopic information regarding free water and bound water around 1850 nm was investigated by using the different distance of fiber optic probes. This study would be great help to control the spectroscopic information of water to be measured depending the site where water exists.

• Structural Monitoring and Maintenance
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• v.2 no.2
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• pp.145-164
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• 2015

Bridge scour is the predominant cause of overwater bridge failures in North America and around the world. Several sensing systems have been developed over the years to detect the extent of scour so that preventative actions can be performed in a timely manner. These sensing systems have drawbacks, such as signal inaccuracy and discontinuity, installation difficulty, and high cost. Therefore, attempts to develop more efficient monitoring schemes continue. In this study, the viability of using optical dissolved oxygen (DO) probes for monitoring scour depths was explored. DO levels are very low in streambed sediments, as compared to the standard level of oxygen in flowing water. Therefore, scour depths can be determined by installing sensors to monitor DO levels at various depths along the buried length of a bridge pier or abutment. The measured DO is negligible when a sensor is buried but would increase significantly once scour occurs and exposes the sensor to flowing water. A set of experiments was conducted in which four dissolved oxygen probes were embedded at different soil depths in the vicinity of a mock bridge pier inside a laboratory flume simulating scour conditions. The results confirmed that DO levels jumped drastically when sensors became exposed during scour hole evolution, thereby providing discrete measurements of the maximum scour depth. Moreover, the DO probes could detect any subsequent refilling of the scour hole through the deposition of sediments. The effect of soil permeability on the sensing response time was also investigated.

• International Journal of Oral Biology
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• v.41 no.2
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• pp.97-103
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• 2016

Mammals have 3 pairs of major salivary glands i.e., the parotid, submandibular, and sublingual glands. Saliva secretion of these glands is modulated by taste perception. Salivary glands are composed mainly of acinar and ductal cells. Primary saliva is secreted by acinar cells and modified during ductal flow. Recently, of the murine 35 bitter taste receptors, Tas2r108 was expressed at highest levels in the submandibular gland by qPCR. Further, Tas2r108-transfected cells respond to a range of bitter compounds, such as denatonium, quinine, colchicine, diphenidol, caffeine and dapson. The objective of the present study was to characterize the expression of Tas2r108 mRNA in acinar and/or ductal cells of the submandibular gland using in situ hybridization (ISH). Male 42-60 days old DBA2 mice were used in the study. Messenger RNAs were extracted from the submandibular gland for generating digoxigenin (DIG) labeled-cRNA probes. These probes were transcribed in anti-sense and sense orientation using T7 RNA polymerase. Dot blot hybridization was performed using DIG labeled-cRNA probes, in order to estimate integrity and optimal diluting concentration of these probes. Subsequently, ISH was performed on murine submandibular gland to detect Tas2r108 mRNA. Dot blot hybridization data demonstrated that Tas2r108 DIG labeled-cRNA anti-sense probes specifically detected Tas2r108 cDNA. ISH results showed that the anti-sense probes labeled acinar and ductal cells in the submandibular gland, whereas no staining was visible in sense controls. Interestingly, the Tas2r108 expression levels were higher in acinar than ductal cells. These results suggested that Tas2r108 might be more associated with primary saliva secretion than with ductal modification of saliva composition.

• Proceedings of the Korea Electromagnetic Engineering Society Conference
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• 2005.11a
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• pp.443-447
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• 2005

The SAR measurement system with stationary probes, presented in this paper, can calculate area SAR value based ell the measured 9 electric field data. By converting obtained area SAR to the volume SAR, the results can be acquired in a few seconds. The system can be very useful tool in the stages of handset development for mobile communication as well as in the handset production line because of its rapid SAR measurement. The system showed good linearity characteristics at 835 MHz of 10 $\sim$ 27 dBm input power range.

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.407.3-408
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• 2002

A portable near infrared (NIR) system which was newly integrated by our lab has been used to develop a non-invasive blood glucose monitoring. The portable NIR system includes a tungsten halogen lamp, a photo diode array type-InGaAs detector, and specialized reflectance fiber optic probes. The shape of probes is composed of two parts. one for illumination into sample and the other for receiving the radiation from sample. Three kinds of probes with different distance between illumination and receiving part. such as 0.03. 0.1. and 0.5mm, were investigated for optimization. (omitted)

• 제어로봇시스템학회:학술대회논문집
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• 2005.06a
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• pp.586-589
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• 2005

Recently, the applications of unmanned system are steadily increasing. Unmanned automatic system is suitable for routine mission such as reconnaissance, environment monitoring, resource conservation and investigation. Especially, for the ocean environmental probe mission, many ocean engineers had scoped with the routine and even risky works. The unmanned surface vessel designed for sea probes can replace the periodic and routine missions such as water sampling, temperature and salinity measuring, etc. In this paper, an unmanned surface vessel was designed for ocean environmental probe missions. A classical and an adaptive fuzzy control system were designed and tested for the unmanned surface vessel. The design methodologies and performance of the surface vessel and fuzzy control algorithm were illustrated and verified with this unmanned vessel system designed for sea probes.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.6 no.2
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• pp.139-145
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• 2020

Polo-like kinase 1 (Plk1) is a key protein in mitosis and has been validated as a target for tumor therapy. It is well known to highly overexpress in many kinds of tumor, which has been implicated as a potential biomarker for tumor treatment and diagnosis. Plk1 consists of two domains, the N-terminus kinase domain and the C-terminus polo-box domain (PBD). The inhibitors have been developed for PBD of Plk1, which were shown a high level of affinity and selectivity for Plk1 that led to mitotic arrest and apoptotic cell death. This review discusses the inhibitors for PBD of Plk1 that are suitable for in vivo tumor treatment. They can be further extended for developing in vivo imaging probes for early diagnosis of tumor.

• Journal of the Korean Society for Nondestructive Testing
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• v.9 no.1
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• pp.39-47
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• 1989

As the necessity of the safety diagnosis of the concrete structure, more reliable ultrasonic technique to qualify the concrete is required. In this study, the artificial surface crack depth is measured using several types of the ultrasonic probes. As results, the horizontal shear wave probe is most useful to determine the crack depth compared to the other probes. For the surface wave probe, the ultrasonic wave path is changed with the surface crack depth.

• Journal of the Korean Society for Nondestructive Testing
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• v.10 no.1
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• pp.18-23
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• 1990

In materials with the large grain size, ultrasonic waves are highly attenuated by the grain boundary acting as scattering centers due to discontinuity of elastic constant. In this study, the improved probes were developed so that they minimized the effect of grain scattering in order to detect deep flaws in coarse grained materials. As the result, the developed ultrasonic transducers showed the better sensitivity and signal to noise ratio when compared with the commercial probes in testing the interior of coarse grained material.

• Journal of Embryo Transfer
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• v.12 no.2
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• pp.203-209
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• 1997

This study was carried out to compare the actual size(length and height) of ovaries, follicles and corpora lutea of Korean native cow with those on sonograms. We used 3 different probes(3.5 MHz abdominal probe, 6.5 MHz transvaginal probe and 5.0 MHz transrectal probe) and a calipher for measurements of ovaries, follicles and corpora lutea on sonograms and actual size. Under water immersion, 157 ovaries were scanned with 3 probes and measured in actual size and compared each other. The average height and width of ovaries of Korean native cows were 17.40$\pm$3.99 and 34.23$\pm$6.02mm, respectively. In comparison of height, length of ovaries and preovulation follicles, we found that image with a transvaginal probe was nearly the same as the actual size(p<0.01), but with an abdominal probe the image was appeared larger than the actual size. In measurement(diameter) of preovulation follicles the transvaginal probe was proven to be more accurate to the actual size than other probes and in corpus luteum measurement all probes were accurate. In the comparison of number of follicles by different size ranges, there was no statistical difference in the count of follicles over 10 mm in diameter between the transvaginal probe and naked eyes.