• 제목/요약/키워드: ARRHYTHMIA

Search Result 601, Processing Time 0.023 seconds

Prediction of arrhythmia using multivariate time series data (다변량 시계열 자료를 이용한 부정맥 예측)

  • Lee, Minhai;Noh, Hohsuk
    • The Korean Journal of Applied Statistics
    • /
    • v.32 no.5
    • /
    • pp.671-681
    • /
    • 2019
  • Studies on predicting arrhythmia using machine learning have been actively conducted with increasing number of arrhythmia patients. Existing studies have predicted arrhythmia based on multivariate data of feature variables extracted from RR interval data at a specific time point. In this study, we consider that the pattern of the heart state changes with time can be important information for the arrhythmia prediction. Therefore, we investigate the usefulness of predicting the arrhythmia with multivariate time series data obtained by extracting and accumulating the multivariate vectors of the feature variables at various time points. When considering 1-nearest neighbor classification method and its ensemble for comparison, it is confirmed that the multivariate time series data based method can have better classification performance than the multivariate data based method if we select an appropriate time series distance function.

Association of Arrhythmia in the Elderly Patients on Combination Therapy of CYP3A4 Substrates and Inhibitors with the Korean Claims Data (CYP3A4 기질과 억제제 약물의 병용 고령환자에서 부정맥 부작용 연관성)

  • Tae Woo Kim;Junhyuk Chang;Eunjung Choo;Rae Woong Park;Sukhyang Lee
    • Korean Journal of Clinical Pharmacy
    • /
    • v.33 no.4
    • /
    • pp.242-253
    • /
    • 2023
  • Background: Arrhythmia due to QT prolongation is one of the most serious adverse events with drug interactions in the elderly. This study aimed to examine the incidence of arrhythmia in Korean elderly patients who administered both cytochrome P450 3A4 (CYP3A4) substrates and inhibitors. Methods: Patients using CYP3A4 substrate and inhibitor were selected from the 2017 elderly patient dataset (the Korean Health Insurance Review and Assessment Service - Aged Population Sample). Selection criteria were patients with a medication possession ratio over 80%, medication duration of at least 7 days, and a follow-up period of 3 months or more. The patient's basic information is age, gender, health insurance type, and comorbidities. The top 50 drug pairs and comorbidity with high-incidence arrhythmia were presented. Results: In patients with drug combinations for over 7 days, there were 981 incidences of arrhythmia, and 351 incidences in those with combinations for over 30 days. The comorbidities of congestive heart failure and myocardial infarction had a significant association with incidence of arrhythmia. Among patients with 7 days or longer, the drug pairs [substrates-inhibitors] with significant adjusted odds ratio (aOR) were [propranolol-cimetidine] (aOR, 2.25; 95% confidence interval [CI], 1.66-3.04). Among patients with 30 days or longer, the drug pairs with significant aOR were [tramadol-amiodarone] (aOR, 2.87; 95% CI, 1.97-4.19). Conclusions: In elderly patients, the incidence of arrhythmia was high with drug interactions of CYP3A4 substrates and inhibitors. The comorbidity of congestive heart failure was the risk factor.

A Investigation into Arrhythmia between East and West medicine (부정맥(不整脈)에 대(對)한 동서의학적(東西醫學的) 문헌고찰(文獻考察))

  • Jeong, Gwang-Sik;Kim, Young-Guen;Kwon, Jung-Nam;Kim, Kyoung-Min
    • The Journal of Internal Korean Medicine
    • /
    • v.21 no.5
    • /
    • pp.747-763
    • /
    • 2000
  • through a literal study upon Arrhythmia between east and west medicine, the results were as follows 1. Arrhythmia is not only irregular cardiac beat but disorder of cardiac impulse making and conduction disturbance. it means almost irregularity of interval between two beat 2. In the east medicine, arrhythmia is represented various category as palpitation, continuous palpitation, dizziness, consumption which give the first consideration by the accompanied symptoms. A separate way in a diagnostics it become a base of diagnosis of diseases and decision of prognosis by the examination of pulse 3. In the west medicine, Arrhythmia is classified as disorder of heart rate, rhythm, conduction disturbance or tachycardia, bradycardia and it is concomitant with fatigue, palpitation, dyspnoea, syncope, chest discomfort 4. The diagnostic study of pulse condition which represent arrhythmia was started from $\mathbb{<}$Nae-Kyung$\mathbb{>}$ and it was revealed as pulse condition of rapid pulse, slow pulse, swift pulse, running pulse, knotted pulse, intermittent pulse etc. Out of them running pulse, knotted pulse, intermittent pulse which obviously are concomitant with irregularity of interval are clinically meaningful in a conditions of disease and decision of prognosis. and the significance of these pulse condition are transformed through the changes of the times 5. According to cause of disease it is classified by Arrhythmia(running pulse, knotted pulse, intermittent pulse) due to heat, cold, phlegm, deficiency(or insufficiency) and There are three categories of etiological factor that is, endogenous, exogenous and non-exo-endogenous factor. the endogenous factor is insufficiency of the heart Ki, deficiency of both Ki and blood, intemal stagnation of phlegm and fluid, stagnation of seven emotions. the exogenous factor is caused by stagnation of Ki and blood by six exogenous pathogenic factor and the non-exo-endgenous factors are improper diet, overstrain, traumatic injury. A cause of arrhythmia in western medicine are a organic and pathological change of the heart itself and malfunction of the autonomic nervous system.

  • PDF

Classification of ECG arrhythmia using Discrete Cosine Transform, Discrete Wavelet Transform and Neural Network (DCT, DWT와 신경망을 이용한 심전도 부정맥 분류)

  • Yoon, Seok-Joo;Kim, Gwang-Jun;Jang, Chang-Soo
    • The Journal of the Korea institute of electronic communication sciences
    • /
    • v.7 no.4
    • /
    • pp.727-732
    • /
    • 2012
  • This paper presents an approach to classify normal and arrhythmia from the MIT-BIH Arrhythmia Database using Discrete Cosine Transform(DCT), Discrete Wavelet Transform(DWT) and neural network. In the first step, Discrete Cosine Transform is used to obtain the representative 15 coefficients for input features of neural network. In the second step, Discrete Wavelet Transform are used to extract maximum value, minimum value, mean value, variance, and standard deviation of detail coefficients. Neural network classifies normal and arrhythmia beats using 55 numbers of input features, and then the accuracy rate is 98.8%.

Classification of Premature Ventricular Contraction using Error Back-Propagation

  • Jeon, Eunkwang;Jung, Bong-Keun;Nam, Yunyoung;Lee, HwaMin
    • KSII Transactions on Internet and Information Systems (TIIS)
    • /
    • v.12 no.2
    • /
    • pp.988-1001
    • /
    • 2018
  • Arrhythmia has recently emerged as one of the major causes of death in Koreans. Premature Ventricular Contraction (PVC) is the most common arrhythmia that can be found in clinical practice, and it may be a precursor to dangerous arrhythmias, such as paroxysmal insomnia, ventricular fibrillation, and coronary artery disease. Therefore, we need for a method that can detect an abnormal heart beat and diagnose arrhythmia early. We extracted the features corresponding to the QRS pattern from the subject's ECG signal and classify the premature ventricular contraction waveform using the features. We modified the weighting and bias values based on the error back-propagation algorithm through learning data. We classify the normal signal and the premature ventricular contraction signal through the modified weights and deflection values. MIT-BIH arrhythmia data sets were used for performance tests. We used RR interval, QS interval, QR amplitude and RS amplitude features. And the hidden layer with two nodes is composed of two layers to form a total three layers (input layer 0, output layer 3).

Nonpharmacological treatment of arrhythmia (소아 부정맥의 비약물적 치료)

  • Bae, Eun-Jung
    • Clinical and Experimental Pediatrics
    • /
    • v.49 no.9
    • /
    • pp.930-936
    • /
    • 2006
  • Although antiarrhythmic medication has been the main treatment modality for arrhythmia in children, in recent decades technological development and computerization have made great advances in nonpharmacological therapy. This article reviews the transcatheter radiofrequency ablation for tachycardia in children, recent advances of device therapy for bradycardia, antitachycardia pacing, implantable cardioverter defibrillator. As a new field of device therapy, cardiac resynchronization therapy for congestive heart failure is also mentioned.

Multi-channel Real Time Arrhythmia Detection System (다중채널 실시간 부정맥 검출 시스템 설계에 관한 연구)

  • 이경중;송향봉
    • Journal of Biomedical Engineering Research
    • /
    • v.8 no.2
    • /
    • pp.215-222
    • /
    • 1987
  • This paper describes the design of a real time arrhythmia detection system using five variables : heart rate, QS width, morphology, alls deviation, and ST segment. To detect individual variables for four patients, we designed multi-processor system. The results of the analysis derived from simulators and 50 patients are compared with the medical diagnoses. The results show that the analysis was able to detect irregularly occuring arrhythmia which does not show up in routine medical examination.

  • PDF

Classification of ECG Arrhythmia Signals Using Back-Propagation Network (역전달 신경회로망을 이용한 심전도 파형의 부정맥 분류)

  • 권오철;최진영
    • Journal of Biomedical Engineering Research
    • /
    • v.10 no.3
    • /
    • pp.343-350
    • /
    • 1989
  • A new algorithm classifying ECG Arrhythmia signals using Back-propagation network is proposed. The base-line of ECG signal is detected by high pass filter and probability density function then input data are normalized for learning and classifying. In addition, ECG data are scanned to classify Arrhythmia signal which is hard to find R-wave. A two-layer perceptron with one hidden layer along with error back-propagation learning rule is utilized as an artificial neural network. The proposed algorithm shows outstanding performance under circumstances of amplitude variation, baseline wander and noise contamination.

  • PDF

SIMILARITY ANALYSIS OF HEART ARRHYTHMIA WITH FLUID VORTEX-NUMERICAL APPROACH (유체와류현상과 심장부정맥의 상관성 연구-수치적 접근)

  • Shim, E.B.
    • 한국전산유체공학회:학술대회논문집
    • /
    • 2010.05a
    • /
    • pp.221-223
    • /
    • 2010
  • Considering the similarity between fluid vortex and arrhythmogenic reentrant waves in heart, we applied the non-dimensionalization method in fluid dynamics to arrhythmia analysis and discovered a new non-dimensional simulation results, there was a threshold value of the number that resulted in the induction of a reentrant wave.

  • PDF