• Proceedings of the IEEK Conference
• /
• 2007.07a
• /
• pp.345-346
• /
• 2007

In this paper, we propose a Pyramid VQ(PVQ) to quantize the transform coefficients of TCX module for the music improvement of AMR-WB+ codec. The proposed PVQ is compared to the $RE_8$ Lattice VQ used in the AHR-WB+ standard codec, demonstrating improvement 4% and 5.7%, respectively, in Mean Squared Error(MSE) and 3.3% and 4.7%, respectively, in Perceptual Evaluation of Audio Quality(PEAQ) by 8-dimensional and 16-dimensional Pyramid VQ.

• Journal of Integrative Natural Science
• /
• v.7 no.1
• /
• pp.5-10
• /
• 2014

A study that copolymerized Ag nanoparticle and furfuryl isocyanate with the crosslinking agent EGDMA (ethylene glycol dimethacrylate), HEMA (2-hydroxyethyl methacrylate), MMA (methyl methacrylate), MA (methacrylic acid) and the initiating agent AIBN (azobisisobutyronitrile) is presented. Measurement of the physical characteristics of the produced macromolecule showed that the water content is 32.08~32.67%, refractive index 1.446~1.448, visible light transparency 83.2~67.6%, contact angle $68.2{\sim}83.5^{\circ}$ and tensile strength 0.541~0.755 kgf. It is also demonstrated that the addition of Ag nanoparticles is associated with the reduction of UV-B transmittance and increase in tensile strength. The results show that the produced copolymer can be used as a material for ophthalmic lenses with durability and UV-blocking properties.

• Clinical and Experimental Pediatrics
• /
• v.63 no.3
• /
• pp.104-109
• /
• 2020

Background: It is challenging to diagnose asthma in preschool children. The asthma predictive index (API) has been used to predict asthma and decide whether to initiate treatment in preschool children. Purpose: This study aimed to investigate the association between questionnaire-based current asthma with API, pulmonary function, airway hyperreactivity (AHR), fractional expiratory nitric oxide (FeNO), and atopic sensitization in preschool children. Methods: We performed a population-based cross-sectional study in 916 preschool children aged 4-6 years. We defined current asthma as the presence of both physician-diagnosed asthma and at least one wheezing episode within the previous 12 months using a modified International Study of Asthma and Allergies in Childhood questionnaire. Clinical and laboratory parameters were compared between groups according to the presence of current asthma. Results: The prevalence of current asthma was 3.9% in the study population. Children with current asthma showed a higher rate of positive bronchodilator response and loose and stringent API scores than children without current asthma. The stringent API was associated with current asthma with 72.2% sensitivity and 82.0% specificity. The diagnostic accuracy of the stringent API for current asthma was 0.771. However, no intergroup differences in spirometry results, methacholine provocation test results, FeNO level, or atopic sensitization rate were observed. Conclusion: The questionnaire-based diagnosis of current asthma is associated with API, but not with spirometry, AHR, FeNO, or atopic sensitization in preschool children.

• The Korean journal of internal medicine
• /
• v.33 no.6
• /
• pp.1210-1223
• /
• 2018

Background/Aims: The co-occurrence of obesity aggravates asthma symptoms. Diet-induced obesity increases helper T cell (TH) 17 cell differentiation in adipose tissue and the spleen. The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor pravastatin can potentially be used to treat asthma in obese patients by inhibiting interleukin 17 (IL-17) expression. This study investigated the combined effects of pravastatin and anti-IL-17 antibody treatment on allergic inflammation in a mouse model of obesity-related asthma. Methods: High-fat diet (HFD)-induced obesity was induced in C57BL/6 mice with or without ovalbumin (OVA) sensitization and challenge. Mice were administered the anti-IL-17 antibody, pravastatin, or both, and pathophysiological and immunological responses were analyzed. Results: HFD exacerbated allergic airway inflammation in the bronchoalveolar lavage fluid of HFD-OVA mice as compared to OVA mice. Blockading of the IL-17 in the HFD-OVA mice decreased airway hyper-responsiveness (AHR) and airway inflammation compared to the HFD-OVA mice. Moreover, the administration of the anti-IL-17 antibody decreased the leptin/adiponectin ratio in the HFD-OVA but not the OVA mice. Co-administration of pravastatin and anti-IL-17 inhibited airway inflammation and AHR, decreased goblet cell numbers, and increased adipokine levels in obese asthmatic mice. Conclusions: These results suggest that the IL-17-leptin/adiponectin axis plays a key role in airway inflammation in obesity-related asthma. Our findings suggest a potential new treatment for IL-17 as a target that may benefit obesity-related asthma patients who respond poorly to typical asthma medications.

• The Korea Journal of Herbology
• /
• v.28 no.5
• /
• pp.87-93
• /
• 2013

Objectives : We recently have reported that constituents of OMC-2010 have an immuno-modulatory effects via inhibiting tumor necrosis factor (TNF)-alpha and interleukin (IL)-5. In this study, based on previous data, we investigated the effects of combinations with each OMC constituents on splenocyte cytotoxicity, cytokine productions, and ovalbumin (OVA) induced experimental allergic asthma. Methods : Mouse splenocytes were pre-treated with ethanol extract of constituents of Rehmannia glutinosa (RG), Pinellia ternata (PT), Schisandra chinensis (SC). We made 4 combinations using RG, PT, and SC (A;1:1:1, B;2:1:1, C;1:2:1, D;1:1:2). The cells were pretreated with A, B, C, or D for 1 h, then stimulated with lipopolysaccharide (LPS, $1{\mu}g/ml$) for 48 h. Then the cells were harvested for real-time reverse transcription polymerase chain reaction to detect cytokine productions. Then using effective combination from RG, PR and SC, we administrated the combination orally, then challenged with OVA to induce asthma. Then we analyzed the airway hyper-reactivity (AHR), lung histology and lung TNF-${\alpha}$ and IL-5 mRNA. Results : A. B. C. and D did not showed significant cytotoxicity on splenocytes. Pre-treatment of A inhibited the expression of TNF-${\alpha}$ and IL-5 significantly, but not B, C, and D. In experimental asthma, administration of A significantly inhibited the increase of AHR, lung damage, TNF-${\alpha}$ and IL-5 expression. Conclusions : Theses results could suggest that inhibitory effects of the ideal combination with RG, PT and SC (1:1:1) could be applied to treatment of asthma and study of asthma mechanisms.

• Journal of Institute of Control, Robotics and Systems
• /
• v.21 no.12
• /
• pp.1167-1172
• /
• 2015

This paper describes the implementation of wearable AHRS for an electromagnetic motion capture system that can trace and analyze human motion on the principal nine axes of inertial sensors. The module provides a three-dimensional (3D) attitude and heading angles combining MEMS gyroscopes, accelerometers, and magnetometers based on the extended Kalman filter, and transmits the motion data to the 3D simulation via Wi-Fi to realize the unrestrained movement in open spaces. In particular, the accelerometer in AHRS is supposed to measure only the acceleration of gravity, but when a sensor moves with an external linear acceleration, the estimated linear acceleration could compensate the accelerometer data in order to improve the precision of measuring gravity direction. In addition, when an AHRS is attached in an arbitrary position of the human body, the compensation of the axis of rotation could improve the accuracy of the motion capture system.

• Proceedings of the Korean Society of Veterinary Pathology Conference
• /
• 2003.10a
• /
• pp.46-46
• /
• 2003

Polychlorinated dibenzo-p-dioxins (PCDDs) are widespread, persistant, and highly toxic environmental pollutants. TCDD is the most potent congener among PCDDs and the most thoroughly investigated model compound of this class of chemicals. These compounds elicit a variety of common biochemical and toxic response, including specific binding to the cytosolic AHR [1] and induces a variety of biological response ranging from induction of cytochrome P-450 1A (CYP1A) to liver damage and cancer [2]. This study was carried out to investigate the protective effects of YCY, extract of a cricket, Gryllus bimaculatus, on hepatotoxicity in 6-week-old SD rat exposured to TCDD (omitted)

• Journal of Korean Society of Water and Wastewater
• /
• v.26 no.4
• /
• pp.497-502
• /
• 2012

Anaerobic Digestion Process is evaluated as efficient wastewater treatment process with the removal of high concentrations of organic waste and production of biogas. This study was performed using hybrid anaerobic hybrid reactor (AHR) which consists of anaerobic sludge blanket (UASB) and biofilm-coated filter media was applied for Palm Oil Mill Effluent (POME) for 80 days to know optimum removal efficiency and production of biogas by comparing each part which divided changing Organic Loading Rate (OLR). As a result of this study, the removal efficiency was 90.4 % when the organic loading rate of influent was 15 kg COD/$m^3$/day. Since organic loading rate was up to 20 kg COD/$m^3$/day, the removal rate declined 80.7%. Over loading of influent caused sludge expansion and overproduction of microorganism. Amount of biogas was collected 82.3 L/day and pH was remained 6.9 constantly with balance of alkalinity.

• Journal of Ocean Engineering and Technology
• /
• v.31 no.2
• /
• pp.177-182
• /
• 2017

This paper describes an unscented Kalman filter approach to estimate the bias in magnetic field measurements. A microelectromechanical systems attitude heading reference system (MEMS AHRS) was used to measure the magnetic field, together with the acceleration and angular rate. A magnetic field is usually used for yaw detection, while the acceleration serves to detect the roll and pitch. Magnetic field measurements are vulnerable to distortion due to hard-iron effect and soft-iron effect. The bias in the measurement accounts for the hard-iron effect, and this paper focuses on an approach to estimate this bias. The proposed method is compared with other methods through experiments that implement the navigation of an underwater robot using an AHRS and Doppler velocity log. The results verify that the compensation of the bias by the proposed method improves the navigation performance more than or comparable to the compensation by other methods.

• International Journal of Advanced Culture Technology
• /
• v.6 no.4
• /
• pp.71-79
• /
• 2018

For 299 patients who had undergone cataract surgeries we investigated the difference in visual acuity and refractive power before and after cataract surgery and the clinical change of the visual acuity and the refractive power according to age, gender, hospital visit time and specific medical history. We found the factors affecting preoperative and postoperative outcomes of the cataract patients in metropolitan hospitals by input, process, and outcome and analyzed medical characteristics and patient characteristics as the input variables. T-test and ANOVA have been performed for statistical analysis of functional status, and general status and the technical characteristic as the process variable and the outcome variable of diagnosis. Visual acuity improved significantly in patients who had undergone cataract surgery. However, the change in refractive power did not show a statistically significant difference but only a slight difference. The improvement of male patients was greater than that of female patients. The difference in age was more effective in patients under 50 years old and the effect of cataract surgery was relatively high in patients without the presence of specific medical history. Cataract surgery did not seem to help all of the patients, but it is more effective in improving visual acuity and refractive power. We conclude that simultaneous cataract surgery in both eyes is reasonable in order to have at least the better effect.