• Asian-Australasian Journal of Animal Sciences
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• v.29 no.3
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• pp.419-427
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• 2016

There is a high association of heat shock on the alteration of energy and lipid metabolism. The alterations associated with thermal stress are composed of gene expression changes and adaptation through biochemical responses. Previous study showed that Angelica gigas Nakai (AGN) root extract promoted adipogenic differentiation in murine 3T3-L1 preadipocytes under the normal temperature condition. However, its effect in heat shocked 3T3-L1 cells has not been established. In this study, we investigated the effect of AGN root hot water extract in the adipogenic differentiation of murine 3T3-L1 preadipocytes following heat shock and its possible mechanism of action. Thermal stress procedure was executed within the same stage of preadipocyte confluence (G0) through incubation at $42^{\circ}C$ for one hour and then allowed to recover at normal incubation temperature of $37^{\circ}C$ for another hour before AGN treatment for both cell viability assay and Oil Red O. Cell viability assay showed that AGN was able to dose dependently (0 to $400{\mu}g/mL$) increase cell proliferation under normal incubation temperature and also was able to prevent cytotoxicity due to heat shock accompanied by cell proliferation. Confluent preadipocytes were subjected into heat shock procedure, recovery and then AGN treatment prior to stimulation with the differentiation solution. Heat shocked preadipocytes exhibited reduced differentiation as supported by decreased amount of lipid accumulation in Oil Red O staining and triglyceride measurement. However, those heat shocked preadipocytes that then were given AGN extract showed a dose dependent increase in lipid accumulation as shown by both evaluation procedures. In line with these results, real-time polymerase chain reaction (RT-PCR) and Western blot analysis showed that AGN increased adipogenic differentiation by upregulating heat shock protection related genes and proteins together with the adipogenic markers. These findings imply the potential of AGN in heat shock amelioration among 3T3-L1 preadipocytes through heat shock factor and proteins augmentation and enhanced adipogenic marker expression.

• Publications of The Korean Astronomical Society
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• v.32 no.1
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• pp.179-183
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• 2017

AKARI and the subsequent Herschel Space Observatory have yielded tremendous advancement in our knowledge of the infrared-submillimeter properties of active galaxies and active galactic nuclei, AGN. This short review describes some highlights. Active galaxies are found to do what they are supposed to do: build up their stellar bodies while building up their central black holes.

• Journal of the Korean earth science society
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• v.30 no.1
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• pp.69-80
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• 2009

We investigate the dependence of star formation rate and Active Galaxy Nuclei (AGN) frequency on the bar properties, especially the bar strength, using SDSS DR6. To better represent the bar strength, we divided the bars into 6 classes according to their length and axial ratios. There seems to be a fairly good correlation between the star formation rate derived from $H{\alpha}$ emission lines and the bar strength, whereas there is no apparent correlation between the AGN activity and the bar strength. We interpret that the former correlation is due to the dependence of bar-driven gas inflow on the strength of bar. The lack of correlation between AGN and bar properties suggests that the accretion of gas onto a supermassive black hole (SMBH) is regulated by the interplay between the bar and SMBH. The frequency of AGN seems to be dependent on the background density but the star formation rate does not. It suggests that star formation is a localized phenomenon that is mostly determined by the gas density in a galaxy, while AGN activity is more closely related to the host property such as mass and luminosity that are thought to be dependent on the environment through the density-luminosity relation.

• Korean Journal of Plant Resources
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• v.32 no.4
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• pp.318-324
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• 2019

Angelica gigas Nakai (AGN) is a perennial herb belonging to the family Apiaceae. Its root has been utilized as a traditional medicine in Korea. Also, it contains decursin (D) and decursinol angelate (DA) as major active components. This study was performed to compare the change in content of active components and antioxidant activity between bolting and non-bolting AGN. Bolting AGN (B1) and non-bolting AGN (NB1) were harvested in the end of August. Additional non-bolting AGN (NB2) was harvested in the end of October. The total weight of B1 was 728.7 g, which was 98.5% of NB2 weight. Next, the AGN root (B1, NB1 and NB2) was divided into main root and lateral root. And the AGN aerial part (B1, NB1) was divided into flower, leaf and stem. The two active components, D and DA, and antioxidant activity were analyzed. The D content of B1 was 0.35-1.33% according to the plant parts and the DA content was 0.29-1.07%. In addition, B1 flower and leaf showed higher antioxidant activity than NB2 roots. The results show that B1 contained 15-56% of total major components compared with NB2 main roots, suggesting that B1 could be used as a potential material.

• The Bulletin of The Korean Astronomical Society
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• v.37 no.1
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• pp.48.2-48.2
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• 2012

We present preliminary results of a statistical study on the nuclear activity of compact group galaxies. What triggers Active Galactic Nuclei (AGN) is still a puzzling problem. One of the suggested AGN triggering mechanisms is galaxy-galaxy interaction. Many simulations have shown that gas can be supplied to the center of galaxies during galaxy encounters. In this regard, compact groups of galaxies are an ideal laboratory for studying the connection between galaxy interaction and nuclear activity because of their high densities and low velocity dispersions. We study the environmental dependence of the activity in galactic nuclei using 59 compact groups in the SDSS DR6. Using the emission line data, we classify galaxies in the compact groups. We find that 19% of the compact group galaxies are pure star-forming nuclei, 10% as transition objects, and only 7% of the galaxies in compact groups show the nuclear activity. The AGN fraction of compact group is higher than galaxy clusters, but lower than field environment. Implications of this result will be discussed.

• The Bulletin of The Korean Astronomical Society
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• v.42 no.2
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• pp.73.1-73.1
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• 2017

Reverberation mapping is one of the best way to investigate structure and kinematics of broad-line regions around central supermassive black holes of active galactic nuclei (AGN). It is usually used to estimate masses of supermassive black holes. So far, reverberation mapping studies have achieved good results for dozens of AGN by spectroscopic monitoring. However, spectroscopic monitoring is time consuming and high cost. Here, we present result of photometric reverberation mapping with medium-band observation. We monitored five nearby AGN which are already studied, have short time-lag, and show bright H-alpha emission lines. Observation has been performed for ~3 months with ~3 days cadence using three medium-band filters installed in LSGT (Lee Sang Gak Telescope). We found 0.01-0.06 magnitude variations by differential photometry. Also time-lags between continuum light-curves and H-alpha emission line light-curves are calculated using Javelin software. The result shows that our study and previous studies are consistent within uncertainty range. From verification of availability in this study, photometric reverberation mapping could be used as a powerful tool to measure central supermassive black holes for large samples and high-redshift AGN in the future.

• Journal of The Korean Astronomical Society
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• v.48 no.5
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• pp.277-284
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• 2015

We present our efforts for extending the simultaneous multi-frequency receiver system of the Korean Very Long Baseline Interferometry (VLBI) Network (KVN) to global baselines in order to measure the frequency-dependent position shifts in Active Galactic Nuclei (AGN) jets, the so called core shift effect, with an unprecedented accuracy (a few micro-arcseconds). Millimeter VLBI observations with simultaneous multi-frequency receiver systems, like those of the KVN, enable us to explore the innermost regions of AGN and high precision astrometry. Such a system is capable of locating the frequency dependent opacity changes accurately. We have conducted the feasibility test-observations with the interested partners by implementing the KVN-compatible systems. Here we describe the science case for measuring the core shift effect in the AGN jet and report progress and future plans on extending the simultaneous multi-frequency system to global baselines.

• The Bulletin of The Korean Astronomical Society
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• v.35 no.2
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• pp.34.1-34.1
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• 2010

Studies suggest that activities in luminous AGNs, residing mostly in early-type galaxies, are triggered by merging. However, the observational evidence for the connection between mergers and AGN activity is not clear yet because tracer of the past merging activities such as tidal tail, shell are often too faint. To see if we can reveal the merging features with a small telescope, we observed an AGN, MARK 478, at z=0.077 with long exposure time (7550 seconds) in V filter at Maidanak observatory. Our 2-D fitting analysis shows that the host galaxy of MARK 478 has the bulge to the total luminosity ratio of 0.3. And the residual image, after subtracting point spread function (PSF), bulge and disk components, shows that the host galaxy has an arm-like feature that could be a spiral arm or a feature from minor merging. We also show that the structural parameters obtained from our 2-D fitting match well with those derived from HST image. The promising result suggests that studies of low redshift AGN host galaxies are possible with data from a small telescope. In order to allow a statistical analysis, we hope to expand our sample size in future.

• Journal of The Korean Astronomical Society
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• v.34 no.4
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• pp.329-331
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• 2001

We investigate the morphology of Active Galactic Nuclei(AGN) jets. AGN jets propagate over kpc $\~$ Mpc and their beam velocities are close to the speed of light. The reason why many jets propagate over so long a distance and sustain a very collimated structure is not well understood. It is argued that some dimensionless parameters, the density and the pressure ratio of the jet beam and the ambient gas, the Mach number of the beam, and relative speed of the beam compared to the speed of light, are very useful to understand the morphology of jets namely, bow shocks, cocoons, nodes etc. The role of each parameters has been studied by numerical simulations. But more research is necessary to understand it systematically. We have developed 2D relativistic hydrodynamic code to analyze relativistic jets. We pay attention to the propagation velocity which is derived from 1D momentum balance in the frame of the working surface. We show some of our models and discuss the dependence of the morphology of jets on the parameter.

• The Bulletin of The Korean Astronomical Society
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• v.37 no.2
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• pp.238.2-238.2
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• 2012

We report the results of KVN-VERA('KAVA'; KVN and VERA Arrary) AGN WG test observation in 2011 and 2012. The results from these commisioning years show that 'KAVA' is able to produce noble images of radio loud AGNs at 22 and 43GHz. This dedicated high frequency VLBI facility will be especially competitive for the regions where conventional low freuquency facilities see the optically thick part of synchrotron radiation. In the second part of this talk, we report the early science activities of the AGN WG. Sgr A*, Jet acceleration zone of M87, extremely young radio galaxies are the prime cadidates of the joint activities. Lastly we will stress how the phase-referencing 'KAVA' does enhance the imaging sensitivity and open new era of VLBI AGN researches.