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The study of caries activity test by multiplex-quantity real time PCR with easy perio test (구강세균 유전자 검사(easy perio test)법을 이용한 치아우식 검사)

  • Yun, Han Gyeol;Park, Seong Gyu;Kim, Jin
    • Journal of Korean Academy of Dental Administration
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    • v.6 no.1
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    • pp.11-18
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    • 2018
  • The aim of this study was to evaluate the competency of the Easyperio test, a genetic test method based on real time PCR for the detection of bacteria that cause dental caries and periodontal disease. To verify the validity of this text, various dental health evaluations were administered to 33 boys between the ages of 12 to 14, as this age group commonly experiences dental caries. These evaluations included a dental caries experience survey, a first molar health evaluation, the Dentocult Streptococcus mutans (SM) strip mutans, the Dentocult Lactobacillus spp (LB) test, and the Easyperio test. The correlation coefficients between the level of the Dentocult SM strip mutans and the dental caries experience were DT (R=0.570, p=0.001), DMFT (R=0.376, p=0.031), and first molar health (R=-0.395, p=0.023). The correlation coefficients between the amount of SM in the Easyperio test and dental caries experience were DT (R=0.528, p=0.002), DMFT (R=0.369, p=0.035), and first molar health (R=-0.426, p=0.013). The correlation coefficients between the level of the dentocult SM strip mutans and the SM amounts of the Easyperio test were S.mi (R=0.564 p=0.001) and S.mu (R=0.621, p=0.002). The correlation coefficients between the level of the Dentocult LB test and the SM amount of Easyperio test was S.mi (R=0.495, p=0.003). In conclusion, Easyperio test may be an easy and effective method for the differentiation and diagnosis of dental caries through quantitative and qualitative analysis of oral bacteria.

The Association of Waist to Height Ratio and Resting Heart Rate with Cardio-metabolic Risk Factors in Korean Postmenopausal Women (한국 폐경 여성의 허리둘레/신장비 및 안정시 심박수와 심혈관-대사 위험요인과의 상관성)

  • Park, Ha-Nui;Byeon, Ji-Yong;Jeon, Justin Y.
    • Exercise Science
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    • v.28 no.1
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    • pp.82-90
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    • 2019
  • PURPOSE: The purpose of this study was to examine the association of waist to height ratio (WHtR) and resting heart rate (RHR) with cardio-metabolic risk factors among Korean postmenopausal women. METHODS: A cross-sectional analysis was performed using the 2015 Korea National Health and Nutrition Examination Survey. The analysis included a total of 1,540 postmenopausal women. RESULTS: Individuals with higher WHtR (>0.56) showed significantly higher glucose, triglyceride, insulin, Homeostatic Model Assessment for Insulin resistance (HOMA-IR), total cholesterol, systolic and diastolic blood pressure compared with ones with lower WHtR (≤0.51). Similar findings were found in those with higher RHR (≥90 bpm) compared with ones with lower RHR (<60 bpm) for glucose and HOMA-IR. When determining the combined effects of WHtR and RHR on the prevalence of metabolic syndrome, individual with WHtR above 0.5 and RHR above 80 bpm showed 10.39 times higher prevalence of metabolic syndrome compared with those with WHtR below 0.5 and RHR below 70 bpm. We further performed multiple linear regression analysis to understand how WHtR and RHR contribute to fasting glucose, and found that both WHtR and RHR contribute to fasting glucose levels independent of age, education level, marital status and income level. CONCLUSIONS: The current study showed that the WHtR and RHR are associated with cardio-metabolic risk factor and prevalence of metabolic syndrome in Korean postmenopausal women.

The analysis of stress reactions ana coping patterns of cancer patients who perceived stress by radiotherapy. (방사선요법을 받는 암환자의 스트레스 지각에 따른 반응과 대체유형의 분석)

  • BANG DONG WAN;KIM JIN SU;PARK GIL YONG;SON MI SUK
    • The Journal of Korean Society for Radiation Therapy
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    • v.13 no.1
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    • pp.1-13
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    • 2001
  • I. Purpose This study is performed to encourage cancer patients to identify, relieve and effectively overcome the stress caused by radiotherapy, by analyzing stress reactions and coping patterns of cancer patients who perceived stress due to radiotherapy. II. Materials & Methods The study group was composed of 85 cancer patients of the age 20 or higher who were undergoing radiotherapy in four hospitals located in Seoul and Kyonggi-do. The survey questionnaire was used, which had 161 questions inquiring respondents of general status, perceived stress, stress reactions and coping patterns. The surveyed data were analyzed by a SAS program, which employed descriptive statistics. Pearson Correlation Coefficient, t-test, ANOVA and Stepwised Multiple Regression. III. Results The stress perception and reaction rates were low in cancer patients comparing to patients of the other study. In the coping patterns. the problem-focused coping patterns were significantly higher than emotion-focused coping patterns. The statistically meaningful differences were observed in the stress perception and reactions depending on the time of diagnosis and perceived health level. As for the problem-focused coping patterns, significant differences were found depending on age, marital status, education, income and the number of family members as well as perceived health level of patients. The level of perceived stress and that of stress reactions was found to have positively significant correlation(r=.764, p<.001) while the perceived stress and the problem-focused coping patterns was correlated negatively (r=-.288, p<.01). The stress reactions and the problem-focused coping patterns was found to have negatively significant correlation(r=-.289, p<.01). IV. Conclusion The problem-focused coping behavior, which cooperated with doctors, technologists, nurses and families of cancer patients, is advisable for the cancer patients to overcome uncertainty and uneasiness by effectively release the stress.

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The Relationship Among Urinary Incontinence, Menopausal Symptom and Life Satisfaction in Middle Aged Women (일 지역 중년여성의 요실금.갱년기 증상과 생활만족도와의 관계)

  • Lim, Hyun-Ja
    • Women's Health Nursing
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    • v.7 no.2
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    • pp.157-168
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    • 2001
  • The purpose of this study was to investigate of the relationship of the urinary incontinence, menopausal symptom and life satisfaction in middle aged women. The subjects of this study were 235 middle aged women, living in M city, during the period from June 21 to August 31, 2000. The instruments for this study were the urinary incontinence modified and adding by Lee Young Sook(1994), the menopausal symptom developed by Song Ae Ri and Chung Eun Soon(1998) and the life satisfaction translated and modified by Suh Kyung Hee(1988). Collected data were analyzed using descriptive statistics, t-test, ANOVA, Pearson correlation coefficients and stepwise multiple regression with SAS package. The result of this are as follows : 1. The total mean score of urinary incontinence was $1.56{\pm}0.58$ with a range of 0 to 4. The mean score on the menopausal symptom was $2.05{\pm}0.43$ with a range of 1 to 4. The mean life satisfaction score was $1.14{\pm}0.41$ with a range of 0 to 2. 2.General characteristics ralated to urinary incontinence were age and numbers of children (F=7.66, p=0.000, F=2.86, p=0.037). General characteristics ralated to menopausal symptom were age (F=7.37, p=0.000), occupation (t=5.33, p=0.021), problem of children (t=6.46, p=0.011) and marital satisfaction (F=5.65, p=0.004). General characteristics ralated to life satisfaction were type of housing (t=12.06, p=0.000), problem of children (t=6.96, p=0.008) and marital satisfaction (F=18.86, p=0.000). 3.The urinary incontinence and menopausal symptom were correlated positively (r=.235, p=.000). The urinary incontinence and life satisfaction were correlated negatively (r=-.114, p=.007). The menopausal symptom and life satisfaction were correlated negatively (r=-.277, p=.000). 4.The menopausal symptom, type of housing and marital satisfaction explained 16.6% of the variance for life satisfaction in the middle aged women.

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Interleukin-10 Polymorphisms in Association with Prognosis in Patients with B-Cell Lymphoma Treated by R-CHOP

  • Kim, Min Kyeong;Yoo, Kyong-Ah;Park, Eun Young;Joo, Jungnam;Lee, Eun Young;Eom, Hyeon-Seok;Kong, Sun-Young
    • Genomics & Informatics
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    • v.14 no.4
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    • pp.205-210
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    • 2016
  • Interleukin-10 (IL10) plays an important role in initiating and maintaining an appropriate immune response to non-Hodgkin lymphoma (NHL). Previous studies have revealed that the transcription of IL10 mRNA and its protein expression may be infl uenced by several single-nucleotide polymorphisms in the promoter and intron regions, including rs1800896, rs1800871, and rs1800872. However, the impact of polymorphisms of the IL10 gene on NHL prognosis has not been fully elucidated. Here, we investigated the association between IL10 polymorphisms and NHL prognosis. This study involved 112 NHL patients treated at the National Cancer Center, Korea. The median age was 57 years, and 70 patients (62.5%) were men. Clinical characteristics, including age, performance status, stage, and extra-nodal involvement, as well as cell lineage and International Prognostic Index (IPI), were evaluated. A total of four polymorphisms in IL10 with heterozygous alleles were analyzed for hazard ratios of overall survival (OS) and progression-free survival (PFS) using Cox proportional hazards regression analysis. Diffuse large B-cell lymphoma was the most common histologic type (n = 83), followed by T-cell lymphoma (n = 18), mantle cell lymphoma (n = 6), and others (n = 5). Cell lineage, IPI, and extra-nodal involvement were predictors of prognosis. In the additive genetic model results for each IL10 polymorphism, the rs1800871 and rs1800872 polymorphisms represented a marginal association with OS (p = 0.09 and p = 0.06) and PFS (p = 0.05 and p = 0.08) in B-cell lymphoma patients treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP). These findings suggest that IL10 polymorphisms might be prognostic indicators for patients with B-cell NHL treated with R-CHOP.

Effect of Diltiazem Cardioplegia on the Myocardial Protection and Functional Recovery of the Isolated Perfused Rat Heart (적출된 작업성 쥐심장에서 Diltiazem 심정지액이 심근보호 및 심근기능 회복에 미치는 영향)

  • 최종범
    • Journal of Chest Surgery
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    • v.21 no.6
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    • pp.970-978
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    • 1988
  • There is tendency of increasing number and decreasing age of patients who are indicated for Rastelli operation for their cyanotic congenital heart disease. So there is the need to find the criterion which saves the patients from early postoperative hemodynamic disturbances. We reviewed the 26 patients who had been performed Rastelli operation at Seoul national University Hospital from January 1981 to June 1988. mean age of the patients was 7.8*3.4 years[range 2.5-15years], mean body surface area[BSA] 0.79*0.25m2[range 0.49-1.51m2] and mean hematocrit 57.95*12%[range 48-80%]. We divided these patients into survived group and died group before postoperative 72 hours, and analyzed preoperative arterial oxygen saturation[SaO2], the ratio of diameter of right pulmonary artery to ascending aorta[RPA/AA], the ratio of both right and left pulmonary artery diameter to descending thoracic aorta[RPA+LPA/DTA], pulmonary artery index[PA index], cardiopulmonary bypass time, aorta cross-clamping time, postoperative perfusion state and total amount of dopamine infused postoperatively. The results showed that RPA+LPA/DTA and PA index were statistically significant factors to influence early postoperative cardiac death rate[P< 0.05]. Especially there were good linear correlations between PA index[X] and peripheral perfusion index[Y][Y= - 1.15+0.02 X, r=0.86, P<0.01]and between PA index[X] and total amount of dopamine infused before postoperative 72 hours[mg/kg, Y][Y=61.94 - 0.15 X, r=-0.80, P < 0.01]. Also there were tendencies that the higher RPA+LPA/DTA[Y], the better peripheral perfusion [X] and the lower need of dopamine[X], but no statistical significance.[Y=0.78+1.60 X, r =0. 49, P >0.05] And the discriminate analysis showed that patients with PA index over 221 mm2/BSA could undergo correction with 25 per cent of error rate. In conclusion, early postoperative hemodynamic states could be predicted by preoperatively measured PA index, and which can be used as a criterion for Rastelli operation performed on cyanotic congenital heart disease.

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A Study on the Fatigue and Health Promoting Behavior of Public Health Nurses and Hospital Nurses (임상간호사와 보건간호사의 피로와 건강증진행위에 대한 연구)

  • Kim, Sun-Ok;So, Hee-Young;Kim, Hyun-Li
    • Research in Community and Public Health Nursing
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    • v.14 no.4
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    • pp.699-706
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    • 2003
  • The objective of this study is to find out the difference in perceptional fatigue and health promoting behavior between hospital nurses and public health nurses. The subjects of this study were 141 hospital nurses and 73 public health nurses in Daejeon. Data were collected using a self-reporting questionnaire during the period from the 5th to 16th of March 2003. Collected data were analyzed using SPSS program. Real number, percentage, mean and standard deviation were calculated, and $x^2$-test and t-test, ANOVA, Pearson's correlation coefficient, stepwise multiple regression procedures were carried out. The findings of this study as follows: 1. The mean score of health promoting behavior was 2.71. 2. There were statistically significant differences in health promoting behavior according to age, marital status, family status, residency, educational level, income, the length of work experience and the field of work. (p<0.05) 3. There were statistically significant differences in fatigue according to age, marital status, family status, educational level, income, the length of work experience, perceived health status and the field of work. (p<0.05) 4. The fatigue was found to be in significant negative correlations with health promoting (r=-0.358, p<0.000) and self efficacy (r=-0.314, p<0.000). On the contrary, a significant positive correlation was found between fatigue and perceived barriers (r=0.210, p<00.01). 5. There were five predictors affecting health promoting behavior, which were self-efficacy, income, perceived benefit, fatigue and family support. The most influential factor was self-efficacy that made 31% of prediction, followed by income (6%), perceived benefit (5.2%), fatigue (2.2%) and family support (1.7%) in their order. As a whole, these factors made 46.1% of prediction of health promotion behavior.

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Impact of Self-Esteem and Test Anxiety on Mental Health in students of Dental Hygienics (일부 치위생과 학생의 시험불안, 자아존중감과 정신건강과의 관계)

  • Choi, Hye-Jung;Jun, Soo-Kyung
    • The Journal of Korean Society for School & Community Health Education
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    • v.13 no.1
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    • pp.77-87
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    • 2012
  • This study is a descriptive paper addressing the relationship between test anxiety, self-esteem and the mental health levels of freshmen and third year students of Dental Hygienics. In late 2011, we received a total of 298 questionnaires from freshmen and third year Dental Hygienics students of three South Korean universities, located specifically in Seoul and Gyeonggi-do. The timing of this questionnaire was significant because it was one week prior to midterm examinations. The results were as follows:1. There was a statistically significant relationship between age (t=3.017, p<.001) and grade(t=2.665, p<0.05), subjective health status(t=27.513, p<.001). 2. The lower the participants' reported mental health in general, the higher their level of test anxiety (r=.565, p<.001), broken down into two subdivisions: cognitive text anxiety (r=526, p<.001) and emotional test anxiety (r=.534, p<.001). 3. When considering the factors that influence the general mental health of participants, there were age differences. For first year students, their subjeetive health status (${\ss}$=-.300, p<.001) and test anxiety (${\ss}$=.530, p<.001) were significant. For third year students, this was also true (subjective mental condition: ${\ss}$=-.242, p<.001 and test anxiety: ${\ss}$=.350, p<.001) but self-worth was also significant (${\ss}$=.377, p<.001). The results of this study suggest that the key factors that influence the mental health level of students Dental Hygienics are test anxiety, subjective appraisal of health level, and general self-worth. A systematic approach is therefore needed to improve students' mental health and reduce test anxiety. Health management programs which address and test students' physical health will also be important in improving student performance and welfare.

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The Influence of Leadership of Head Nurses on Job Satisfaction and Job Performance of Staff Nurses (수간호사의 리더십 유형이 일반간호사의 직무만족도와 간호업무성과에 미치는 영향)

  • Shin, Young-Jin;Lee, Byung-Soon
    • Journal of Korean Academy of Nursing Administration
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    • v.6 no.3
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    • pp.405-418
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    • 2000
  • The purpose of this study was to investigate the influence of the leadership of head nurses on the job satisfaction and job performance of staff nurses. The leadership styles of head nurses were classified to "authority-oriented" and "benevolence-oriented" based on korean traditional culture. The subjects of this study were 450 staff nurses working at medical-surgical units, intensive care units, emergency units of general hospitals in Kyungbuk area. Data were collected from March 13 to March 25 with several scales for the measurement of leadership styles of head nurses, job satisfaction and job performance of staff nurses. The Cronchbach alphas for the scales were. 79 in "authority-oriented" leadership style, 90 in "benevolence-oriented" leadership style, .91 in job satisfaction, .97 in job performance. Data were analyzed with SAS program using statistics of percentage, means, standard deviation, Pearson correlation, ANOVA and ANCOVA. The results were : 1. There were significant correlations between benevolence-oriented leadership style and job satisfaction, job performance of staff nurses(r=.24, p=.000 ; r=.12, p=.008), authority-oriented leadership style of head nurses and job satisfaction of staff nurses(r=.12 ; p=.024). 2. There were significant differences in job satisfaction of staff nurses by age and clinical career(F=10.36, p=.000 ; F=7.63, p=.000). Also there were significant differences in job performance of staff nurses by age, religion, marriage and clinical career(F=17.79, p=.000 ; F=2.89, p=.035 ; F=4.41, p=.036 ; F=14.33, p=.000). 3. There was significant differences in job satisfaction by the leadership style of head nurses. The job satisfaction of staff nurses with benevolence-oriented head nurses was higher than those with authority

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Prealbumin and Retinol Binding Proteins Are Not Usable for Nutrition Follow-Up in Pediatric Intensive Care Units

  • Tekguc, Hakan;ozel, Deniz;Sanaldi, Huriye;Akbas, Halide;Dursun, Oguz
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.21 no.4
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    • pp.321-328
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    • 2018
  • Purpose: Feeding children is a problem in pediatric intensive care units (PICU) and it is difficult to know the correct amount. The purpose of this study is to evaluate if prealbumin or retinol binding proteins (RBP) are effective relative to daily enteral nutrition, without being affected by severity of diseases or infections and can be used to follow up nutritional amount. Methods: This is a prospective observational study that includes 81 patients admitted to PICU in Akdeniz University with estimated duration >72 hours, age between 1 month and 8 years. Daily calorie and protein intake were calculated and prealbumin, RBP and C-reactive protein (CRP) levels were measured on the first, third, fifth and seventh mornings. Results: We find moderate correlation between daily calorie intake and prealbumin levels (r=0.432, p<0.001), RBP levels and daily protein intake (r=0.330, p<0.001). When we investigated the relationship between changes of prealbumin, RBP, CRP, calorie and protein intake during intensive care stay, we found that increase of Prealbumin and RBP levels are explained by decrease of CRP levels (r=-0.546 and -0.645, p<0.001) and not with increase of nourishment. Conclusion: Even adjusted for PRISM3, age and CRP, prealbumin and RBP are correlated with last 24 hours' diet. However, it is not convenient to use as a follow up biomarker because increase of their levels is related with decrease of CRP levels.