• Title/Summary/Keyword: AGAC

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LitCovid-AGAC: cellular and molecular level annotation data set based on COVID-19

  • Ouyang, Sizhuo;Wang, Yuxing;Zhou, Kaiyin;Xia, Jingbo
    • Genomics & Informatics
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    • v.19 no.3
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    • pp.23.1-23.7
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    • 2021
  • Currently, coronavirus disease 2019 (COVID-19) literature has been increasing dramatically, and the increased text amount make it possible to perform large scale text mining and knowledge discovery. Therefore, curation of these texts becomes a crucial issue for Bio-medical Natural Language Processing (BioNLP) community, so as to retrieve the important information about the mechanism of COVID-19. PubAnnotation is an aligned annotation system which provides an efficient platform for biological curators to upload their annotations or merge other external annotations. Inspired by the integration among multiple useful COVID-19 annotations, we merged three annotations resources to LitCovid data set, and constructed a cross-annotated corpus, LitCovid-AGAC. This corpus consists of 12 labels including Mutation, Species, Gene, Disease from PubTator, GO, CHEBI from OGER, Var, MPA, CPA, NegReg, PosReg, Reg from AGAC, upon 50,018 COVID-19 abstracts in LitCovid. Contain sufficient abundant information being possible to unveil the hidden knowledge in the pathological mechanism of COVID-19.

Clinical Presentation and Management of Five Dogs with Apocrine Gland Adenocarcinoma of Anal Sac (다섯 마리의 개에서 발생한 아포크린샘암종 증례)

  • Oh, Ye-In;Seo, Kyoung-Won;Kim, Jun-Young;Youn, Jung-Hee;Hwang, Cheol-Young;Lee, Sang-Koo;Youn, Hwa-Young
    • Journal of Veterinary Clinics
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    • v.26 no.6
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    • pp.606-611
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    • 2009
  • Five dogs diagnosed as apocrine gland adenocarcinoma (AGAC) of the anal sac based on cytology and/or histology. Mean age of these dogs was 11 years old. One dog treated with supportive care without other medical interventions for hypercalcemia was died one month after diagnosis. Other four dogs were treated with chemotherapy and one of these dogs was intervened with complete surgical resection. Two months after the diagnosis, one of the dogs treated with chemotherapy died. The survival time of other survived three dogs from the time of diagnosis was 19, 9, and 13 months respectively and they are still alive at this time. After chemotherapy, three dogs were managed generally in good body condition and maintained as similar in size as time of diagnosis. The results are suggested that it is worthwhile to try chemotherapy for managing AGAC in dogs especially complicated or metastasized to regional lymph nodes.