• Molecular & Cellular Toxicology
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• 제2권4호
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• pp.223-228
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• 2006

Several plant-derived cannabinoids and endogenous ligands for cannabinoid receptors such as 2-arachidonyl-glycerol have been known to inhibit interleukin-2 (IL-2) expression. In the present study, we utilized arachidonylethanolamide (AEA), a putative endogenous ligand for cannabinoid receptors, to determine whether AEA modulated the expression of IL-2. AEA inhibited phorbol 12-myristate 13-acetate (PMA) plus ionomycin (Io)-induced IL-2 protein secretion and mRNA expression in EL-4 mouse T-cells as determined by ELISA and RT-PCR, respectively. To further characterize the inhibitory mechanism of AEA at the transcriptional level, we performed promoter study for IL-2 gene in PMA/Io-stimulated EL-4 cells. AEA decreased the transcriptional activity of the nuclear factor of activated T-cells (NF-AT) as well as the IL-2 promoter activity. These results suggest that AEA suppresses IL-2 expression and that the inhibition is mediated, at least in part, through the down-regulation of NF-AT.

• Carbon letters
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• 제11권2호
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• pp.107-111
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• 2010

We prepared the amine epoxy adducts (AEA)/thin multiwalled carbon nanotubes (TWCNTs) composite particles using nonsolvent based methods including dry mechano-chemical bonding(MCB) process and supercritical fluid (SCF) process. The resulting TWCNTs/AEA composite particles have been used as curing agents for urethane modified bispheol A type epoxy resin. The thermal, thermomechanical properties of the epoxy resins cured with TWCNTs/AEA composite particles were measured by DMA and the dispersion of CNT was characterized by SEM. Because of high degree of CNT dispersion, thermal and mechanical properties of the epoxy resin cured with TWCNTs/AEA composite particles prepared by SCF process are better than those cured with mechano-chemically prepared TWCNTs/AEA composite particles.

• 한국연소학회지
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• 제9권4호
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• pp.35-46
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• 2004

Activation energy asymptotics (AEA) for Linan#s premixed-flame regime is revisited in this paper. First, the detailed AEA procedure for the premixed-flame regime is demonstrated, so that the practitioners of AEA could easily apply the method to their own problems. In addition, the controversies surrounding the premixed-flame regime, namely the closure controversy and fast-time instability paradox, are explained. Finally, the limitation of AEA, mainly arising from the wrong prediction of fuel leakage through the reaction zone, is examined and the Zel#dovich-Linan kinetics is introduced as an alternative to meet the needs of modern combustion analysis, where the detailed chemical structure of flame is demanded.

• 한국연소학회:학술대회논문집
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• 한국연소학회 2004년도 제28회 KOSCO SYMPOSIUM 논문집
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• pp.124-132
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• 2004

Activation energy asymptotics (AEA) for Linan's diffusion-flame regime is revisited in this paper. The main purpose of the paper is to carefully re-examine each AEA analysis step in order to clarify the some concepts that are often misunderstood among the ordinary practitioners of the AEA. Particular attention is focused on the different AEA regimes arising from the double limit of large Zel'dovich and Damkohler numbers. In addition. the expansion procedures are shown in detail and the method that the turning point condition, commonly known as the Linan's extinction condition, is found is explained.

• Journal of Mechanical Science and Technology
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• 제17권2호
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• pp.187-196
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• 2003

In this paper, a new methodology of evolutionary computations - An Adaptive Evolutionary Algorithm (AEA) is proposed. AEA uses a genetic algorithm (GA) and an evolution strategy (ES) in an adaptive manner in order to take merits of two different evolutionary computations : global search capability of GA and local search capability of ES. In the reproduction procedure, the proportions of the population by GA and ES are adaptively modulated according to the fitness. AEA is used to. designing fuzzy logic controller (FLC) for a high-angle-of-attack flight system for a super-maneuverable version of F-18 aircraft. AEA is used to determine the membership functions and scaling factors of an FLC. The computer simulation results show that the FLC has met both robustness and performance requirements.

• Archives of Pharmacal Research
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• 제18권5호
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• pp.314-319
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• 1995

Antacid granules were prepared by agglomeration and powder method in high speed agitation type granulator. The copmositions of the test antacids were sodium bicarbonate nad magnesium carbonate nad a coating material was powder of polyvinylacetal diethyl-aminocacetate (AEA) and an additive material was talc powder. The dissolution characteristics of base from the antacid granules were investigated to evaluate neutralization capacity of hydrochloric profile of base and neutralization behavior, the following results were obtained : The prepared granules showed a pH-dependent dissolution pattern of a base. The dissolution profile of a base was varied with addition of talc powder as well as coating amount of AEA. The relationship between the ratio of dissolution retarded time for 20% and 10% AEA. The relationship between the ratio of dissolution retarded time for 20% AEA coated granules $\theta_{20}/\theta_{10}$ and the diameter reduction of the granules was explained by the rate process of neutralization of hydrochloric acid.

• 한국연소학회지
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• 제9권2호
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• pp.1-9
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• 2004

Activation energy asymptotics (AEA) for Linan#s diffusion-flame regime is revisited in this paper. The main purpose of the paper is to carefully re-examine each AEA analysis step in order to clarify the some concepts that are often misunderstood among the ordinary practitioners of the AEA. Particular attention is focused on the different AEA regimes arising from the double limit of large Zel#dovich and Damkohler numbers. In addition, the expansion procedures are shown in detail and the method that the turning point condition, commonly known as the Linan#s extinction condition, is found is explained.

• 조명전기설비학회논문지
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• 제13권4호
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• pp.68-74
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• 1999

본 연구는 고분자재료에서 음향센서를 이용한 부분방전의 음향적 탐지를 행했다. 저밀도 폴리에틸렌에 대한 트리잉파괴 실험에서 음향센서로 얻어진 음향방출 특성의 시간순서대로 측정하여 통계처리를 행했다. 또한 5가지 특성량을 도입하고 $\psi$-AEA-n(위상-음향진폭-펄스수) 패턴을 분석한 결과, 보이드 시료의 AE평균개시진폭 $(\overline{AEA_{inc}})$과 AE 평균최대진폭$(\overline{AEA_{max}})$은 열화중기, AE펄스수, AE평균최대위상각$(\overline{\theta{max}})$은 열화말기를 진단하기 위해서 유용한 음향방출량임을 알 수 있다. 이들 음향방출량은 보이드 시료의 열화진단을 구별하는데 유용한 음향방출량임을 실험결과로부터 얻었다.

• 한국의류학회지
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• 제47권6호
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• pp.1204-1220
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• 2023

With the rising importance placed on sustainability for brands, a plethora of research addresses consumer responses concerning eco-friendly products. While positive effects of eco-friendly traits on beauty products have been discussed, this study addresses a wide research gap in the makeup category. Based on the goal-attribute theory and the lay theory of ethicality, detrimental effects of eco-friendly ingredient claims on perceived appearance enhancement attributes (AEA) were examined. A between-subject, single-factor (eco-friendly ingredient claims present vs. absent) web-based experimental design tested the effect of conditions on makeup products that emphasized AEA. Results found a negative effect of eco-friendly ingredient claims on perceived AEA, supporting previous literature regarding the 'green gap'. Evidence showed that perceived AEA fully mediated the effect of eco-friendly claims on purchase intention, which was moderated by AEA preference. Interestingly, findings show that the purchase intention of respondents with a near-average preference for AEA was not moderated. Results contribute to preexisting literature by extending the lay theory of ethicality and product function mismatch to the field of makeup. Managerial implications are discussed, including opportunities for eco-friendly makeup products to appeal to alternative benefits.

• Journal of Pharmaceutical Investigation
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• 제32권1호
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• pp.41-45
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• 2002

The purpose of this study is to microencapsulate a highly hygroscopic drug, pyridostigmine bromide (PB), with a waterproof wall material, in order to increase the flowability of the drug particles. Polyvinylacetaldiethylaminoacetate (AEA), Eugragit E and Eugragit RS were examined as the wall materials. Microcapsules containing PB were prepared by the evaporation technique in an acetone/liquid paraffin system using aluminum tristearate as a core material, and evaluated for drug encapsulation efficiency, surface morphology, particle size and drug dissolution. The encapsulation of PB in the wall material was almost complete. Among the wall materials examined, AEA exhibited the most excellency in shape, surface texture, flowability, size distribution of microcapsules. Above results suggest that AEA would be a potential wall material for microcapsulation of highly hygroscopic drugs, such as PB. Through microencapsulation with AEA, inconvenience of handling of PB powders encountered in the process of weighing and packing the powders to tableting die or capsule body could be greatly improved.