• Radiation Oncology Journal
• /
• 제37권3호
• /
• pp.215-223
• /
• 2019

Purpose: To determine prognostic significance of lymphovascular invasion (LVI) in prostate cancer patients who underwent adjuvant or salvage postoperative radiotherapy (PORT) after radical prostatectomy (RP) Materials and Methods: A total of 168 patients with prostate cancer received PORT after RP, with a follow-up of ≥12 months. Biochemical failure after PORT was defined as prostate-specific antigen (PSA) ≥0.2 ng/mL after PORT or initiation of androgen deprivation therapy (ADT) for increasing PSA levels regardless of the value. We analyzed the clinical outcomes including survivals, failure patterns, and prognostic factors affecting the outcomes. Results: In total, 120 patients (71.4%) received salvage PORT after PSA levels were >0.2 ng/mL or owing to clinical failure. The 5-year biochemical failure-free survival (BCFFS), clinical failure-free survival (CFFS), distant metastasis-free survival (DMFS), overall survival, and cause-specific survival rates were 78.3%, 94.3%, 95.0%, 95.8%, and 97.3%, respectively, during a follow-up range of 12-157 months (median: 64 months) after PORT. On multivariate analysis, PSA level of ≤1.0 ng/mL at the time of receiving PORT predicted favorable BCFFS, CFFS, and DMFS. LVI predicted worse CFFS (p = 0.004) and DMFS (p = 0.015). Concurrent and/or adjuvant ADT resulted in favorable prognosis for BCFFS (p < 0.001) and CFFS (p = 0.017). Conclusion: For patients with adverse pathologic findings, PORT should be initiated as early as possible after continence recovery after RP. Even after administering PORT, LVI was an unfavorable predictive factor, and further intensive adjuvant therapy should be considered for these patients.

• 한국안전학회지
• /
• 제27권2호
• /
• pp.111-116
• /
• 2012

This study deals with the traffic accidents of circular intersections in Korea. The purposes are to comparatively analyze the characteristics by operational type, and to develop the models using the data of 82 intersections. In pursuing the above, this study gives particular emphasis to modeling such the accidents as the roundabout and rotary in urban area. The main results analyzed are as follows. First, the null hypotheses that the number of accidents are the same in both the urban and rural intersections, and roundabout and rotary in urban area, were analyzed to be rejected. Second, 3 accident models were developed, which were all statistically significant. The independent variables used in the above models are the ADT, number of approach lane, bus stop, parking facilities, and others. This study could be expected to give some implications to the traffic safety policy decision-making.

• Asian Pacific Journal of Cancer Prevention
• /
• 제13권1호
• /
• pp.1-13
• /
• 2012

Metabolic syndrome has become quite prevalent within our society. Over the past two decades, the prevalence of metabolic syndrome has sharply increased worldwide and it has become a major public health problem in several countries. It is associated with the global epidemic of obesity and diabetes mellitus and imposes numerous cardiovascular risks. Prostate cancer is the second most common cancer among men, surpassed only by non-melanoma skin cancer. A considerable body of evidence exists suggesting that some components of the metabolic syndrome have been associated with the risk of prostate cancer. These components include obesity, an abdominal fat distribution, and hyperinsulinemia. Androgen deprivation therapy (ADT) is the most widely used therapeutic modality in prostate cancer. It changed the body composition and lipid profile of men with prostate cancer. Androgen deficiency is associated with increased levels of total cholesterol, low-density lipoprotein (LDL)-cholesterol, increased production of proinflammatory factors, and increased thickness of the arterial wall and contributes to endothelial dysfunction. The aim of this review is to evaluate the association between metabolic syndrome and prostate cancer and to discuss the implications of androgen deficiency in men with cardiovascular risk factors. A comprehensive literature search was carried out with the use of PubMed from 1980 through 2011, and relevant articles pertinent to metabolic syndrome and prostate cancer are evaluated and discussed.

• 전기학회논문지
• /
• 제59권4호
• /
• pp.809-813
• /
• 2010

Although the goals of HL7 Version 2(V2) and Version 3(V3) are identical, the concepts of the implementation and technological basis are different; this makes their versions inconvertible. This problem interrupts technological innovation advanced from V2 to V3 and has been raised as a new type of barrier in the field of medical information system. This study intends to develop software to convert V2 to V3 which can be utilized in the actual medical environment. Since it is practically difficult to develop the whole tools that automatically change total V2 messages into V3 messages, this article has designed, implemented, and tested the software that allows mapping between V2 and V3 which function as tools. In order to test this program, it has used ADT^A03 of five V2 messages to generate V3 messages. It is expected that the result of this research will be one of the new methods allowing conversion between V2 and V3.

• 전력전자학회논문지
• /
• 제21권3호
• /
• pp.267-274
• /
• 2016

In this study, a fast charger for electric vehicle with wide charging voltage range is proposed. To achieve high efficiency, three-level topologies are employed for the AC-DC and DC-DC converters. Given that the output range of the DC-DC converter in fast chargers is quite wide, the circulating current of conventional three-level converter will increase under low voltage condition. The proposed hybrid switching method mitigates this issue. When a coupled inductor is used on the output side, the circulating current is further reduced, and the switches $S_2$, $S_3$, $S_6$, and $S_7$ achieve turning-off under the ZCS condition. Experimental results from a 50 kW prototype are provided to validate the proposed charger, and a rated efficiency of 95.9% is obtained.

• 한국안전학회지
• /
• 제32권4호
• /
• pp.107-113
• /
• 2017

This paper deals with the traffic factors related to the collisions of circular intersections. The purpose of this study is to develop traffic accident models by type of collision based on land use. In pursuing the above, the traffic accident data from 2010 to 2014 were collected from the "Traffic Accident Analysis System (TAAS)" data set of the Road Traffic Authority. A multiple regression model was utilized in this study to develop the traffic accident models by type of collision. 17 explanatory variables such as geometry and traffic volume factors were used. The main results are as follows. First, the null hypothesis that the type of land use does not affect the number of accidents by type of collision is rejected. Second, 10 accident models by type of collision based on land use are developed, which are all statistically significant. Finally, the ADT, inscribed circle diameter, bicycle lane, area of central island, number of speed hump, circulatory roadway width, splitter island, area of circulatory roadway, mean number of entry lane and mean width of entry lane are analyzed to see how they affect accident by type of accident based on land use.

• 한국신뢰성학회지:신뢰성응용연구
• /
• 제17권1호
• /
• pp.66-71
• /
• 2017

Purpose: Polymer capacitors are known to have very high reliability as compared with liquid electrolytic capacitors, but their capacity has been reported to decrease in charge and discharge at low temperature. The purpose of this study to clarify these characteristics. Methods: In order to clarify these characteristics, charging-discharging tests were carried out for 200 hours with three different capacities and at 5 different temperature from $5^{\circ}C$ to $100^{\circ}C$. Results: As a result of the test, it was confirmed that the capacity of the polymer capacitor was decreased with higher capacity and lower temperature. Conclusion: Such a failure phenomenon was caused by the shrinkage and expansion characteristics of the polymer used therein, it is presumed that this failure phenomenon is due to the complex pore structure made by etching.

• 한국신뢰성학회:학술대회논문집
• /
• 한국신뢰성학회 2004년도 정기학술대회
• /
• pp.239-246
• /
• 2004

가속열화시험은 가속수명시험시에 고장 개수가 적거나 심지어 고장이 발생하지 않는 경우에도 부품의 신뢰성을 평가할 수 있는 유용한 수단이 되고 있다. 본 연구에서는, 능동소자로 높은 유전용량을 갖는 적층 세라믹 콘덴서(X7R -55$^{\circ}C$~1$25^{\circ}C$)에 대한 가속열화시험을 실시하고, 정격온도의 최대치에서 다른 배율의 전압을 인가하여 단순선형회귀에 의한 특성치의 경시변화를 설명한다고 가정하였다. 최소제곱법을 적용하여 시료가 대수정규분포를 따를 때의 열화량을 설명한 후, 특성치-시간간의 선형관계 및 대수정규분포의 독립성을 검정하여 가정의 적절성을 검정하였다. 마지막으로 아이링모델에 의한 평균수명을 평가하였다.

• Macromolecular Research
• /
• 제17권3호
• /
• pp.149-155
• /
• 2009

The thermal decomposition behavior and degradation characteristics off our different thermotropic liquid crystalline polymers (TLCPs) were studied. The thermal decomposition behavior was determined by means of thermogravimetric analysis (TGA) at different heating rates in nitrogen and air. The order of the thermal stability was as follows: multi-aromatic polyester > hydroxybenzoic acid (HBA)/hydroxynaphthoic acid (HNA) copolyester > HNA/hydroxyl acetaniline (HAA)/terephthalic acid (TA) copolyester > HBA/Poly(ethylene terephthalate) (PET) copolyester. The activation energies of the thermal degradation were calculated by four multiple heating rate methods: Flynn-Wall, Friedman, Kissinger, and Kim-Park. The Flynn-Wall and Kim-Park methods were the most suitable methods to calculate the activation energy. Samples were exposed to an accelerated degradation test (ADT), under fixed conditions of heat ($63{\pm}3^{\circ}C$), humidity ($30{\pm}4%$) and Xenon arc radiation ($1.10\;W/m^2$), and the changes in surface morphology and color difference with time were determined. The TLCPs decomposed, discolored and cracked upon exposure to ultraviolet radiation.

• 동의신경정신과학회지
• /
• 제32권3호
• /
• pp.261-273
• /
• 2021

The purpose of this study was to introduce effects of Chukyu pharmacopuncture and Brainspotting on knee pain, headaches, and acute stress disorder of a patient with a traffic accident. We treated a patient with Chukyu pharmacopuncture and Brainspotting. Numerical rating scale (NRS), Range of Motion (ROM), Hyperextension Position (HEP), Effusion (Eff), Patella Compression Test (PCT), Frontal Flexion Position (FFP), McMurray (MCM), Lateral Joint Line Tenderness (LJLT), Medial Joint Line Tenderness (MJLT), Anterior Drawer Test (ADT), Lachman Test, Varus/Valgus stress, Beck Anxiety Inventory (BAI), Patient Health Questionnaire-9 (PHQ-9), Pittsburgh Sleep Quality Index (PSQI), Core Seven Emotions Inventory Short Form (CSEI-S), Subjective units of disturbance scale (SUDs), and Heart rate variability (HRV) were used to evaluate the patient. After the patient was treated by Chukyu pharmacopuncture and Brainspotting, the patient showed improvement in NRS, physical examination, and psychological symptom assessment. These results indicate that Chukyu pharmacopuncture and Brainspotting are effective on knee pain, headache, and acute stress disorder after a traffic accident.