• The Journal of Korean Medicine
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• v.29 no.1
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• pp.179-191
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• 2008

Background and Objectives : Atopic dermatitis is a recurrent or chronic eczematous skin disease with severe pruritus,and has increased in Korea. Although the pathogenic mechanisms of atopic dermatitis are yet unknown, recently skin barrier dysfunction and hyperresponsive Th2 cells in the acute phase have been reported as important mechanisms. Cheonggi-san(CGS) is used in oriental clinics for treatingacute skin lesions of eczema or urticaria. There have been no studies on the therapeutic mechanism of CGS for curing atopic dermatitis. We aimed to find out the therapeutic effects of its internaluse on atopic dermatitis-like skin lesions, induced in NC/Nga mice by the mite antigen D. pteronyssinus and disrupting skin barrier. Materials and Methods : The NC/Nga mice were classified into three groups: control group, atopic dermatitis elicitated group(AD), and CGS treated group (CT). Atopic dermatitis-like skin lesions were induced on the back of female NC/Nga mice, 12 weeks of age, by tape stripping, 5% SDS applied to disrupt skin barrier and painting 3 times a week with D. pteronyssinus crude extract solution for 3 weeks. CT was treated with CGS orally after atopic dermatitis was elicitated. We observed changes of skin damage, mast cells, substance P, angiogenesis, skin barrier, Th2 cell differentiation, nuclear factor-${\kappa}B(NF-{\kappa}B)$ p65 activation and COX-2 in NC/Nga mice with atopic dermatitis-like skin lesions. Results : The skin damages as eczema were seenin AD, but mitigated in CT. The degranulated mast cells in dermal papillae increased in AD, but decreased in CT. The substance P positive reacted cells in CT remarkably decreased. The angiogenesis increased in AD, but decreased in CT. The decrease of lipid deposition and ceramide in AD was seen, but anincrease of lipid deposition and ceramide in CT was seen. The distribution of IL-4 positive reacted cells in dermal papillae increased in AD, but decreased in CT. The distribution of NF-${\kappa}B$ p65 positive reacted cells & COX-2 positive reacted cells in CT decreased. Conclusion : The results may suggest that the CGS per os decreases the dysfunction of the skin barrier, inhibits Th2 cell differentiation and inhibits NF-${\kappa}B$ p65 activation in NC/Nga mice with atopic dermatitis-like skin lesions.

• The KIPS Transactions:PartC
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• v.14C no.2
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• pp.191-198
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• 2007

A mobile ad-hoc network (MANET) is an autonomous, infrastructure-less system that consists of mobile nodes. In MANET, on demand routing protocols are usually used because network topology changes frequently. AODV, which is a representative on demand routing protocol, operates using the routing table of each node that includes next hop of a route for forwarding packets. It maintains the established route if there is not an expiration of route or any link break. In the paper, we propose a partially adaptive route maintenance scheme (AODV-PA) based on AODV, which provides dynamic route modification of initial route for selecting the effective route using not only next hop but also next-hop of next-hop (i.e. 2-hop next node) acquired through route discovery process. In addition, the proposed scheme additionally manages the routing table for preventing exceptional link breaks by route modification using HELLO messages. We use NS 2 for the computer simulation and validate that the proposed scheme is better than general AODV in terms of packet delivery ratio, latency, routing overhead.

• Journal of the Korean Society of Clothing and Textiles
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• v.22 no.2
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• pp.267-278
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• 1998

The purpose of this study was to investigate the degree of self-monitoring (SM), the task situation and the appeal type of advertising impact on consumer behavior: in inner wear purchase. Information for the study was obtained with the use of experimental design. the experimental materials for the study were two-type inner wear advertisements (image appeal Ad/product appeal Ad). The subjects were 270, who were randomly sampled women undergraduate students in Korea, and main-test subjects (70 high SM subjects/69 low SM subjects) were assigned to the cells of 2 (self usage/gift-giving)x2 (quality appeal Ad/image appeal Ad). According to the 2x(2$\times$2) mixed factorial design, the level of SM score, the type of task situation score and the level of appeal type of advertising score were compared and tested by analysis of ANOVA. The results of experiment were as follows: 1. Experimental 1. the results showed the product preference on inner wear was the significant 3-way interaction effects among the degree of SM, the task situation, and the appeal type of advertising as well as the significant main effects of the appeal type of advertising. That is, the situation impact differs from the appeal type of advertising according to the degree of SM. 2. Experimental ll. the results showed the purchase intention on inner wear was the significant 2-way interaction effects between the appeal type of advertising and the task situation as well as the significant main effects of the appeal type of advertising and the task situation. That is, there is considerable difference in gift-giving situation rather than in self- usage situation according to the appeal type of advertising.

• The Korea Journal of Herbology
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• v.23 no.1
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• pp.53-61
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• 2008

Objectives : The aim of this study was to investigative the effects of Gagambojungikgi-tang (GBT), a Korean herbal medicine, on the immune mediators, T cell proliferation and wound healing in the recombinant Sj26 (rSj26) antigen induced atopic dermatitis(AD) model mice. Methods : GBT is the water extracts prepared from mixture of Ginseng Radix, Astragali Radix, Angelicae gigantis Radix, Atractylodes Rhizoma alba, Aurantii nobilis Pericarpium, Glycyrrhizae Radix, Artemisia iwayomogi Herba, Scutellaria Radix, Lonicera japonica Flos. This is a modified prescription of Bojungikgi-tang, which has been used for the treatment of indigestion, and immunological disease in east-asian countries. GBT was orally administered or externally applied at difference doses. The levels of immune mediators [(IgE, IgG1, prostaglandin E2 (PGE2), Th1/Th2 cytokines], T cell proliferation, and wound healing in the rSj26 or chemical antigen induced AD model BALB/c were investigated. Results : GBT dose-dependently suppressed the release of TNF-${\alpha}$, IL-$1{\beta}$ (Th1 cytokines), IL-4, IL-10 (Th2 cytokines), PGE2 (inflammatory mediators) and T cell proliferation. But GBT increased the production of IFN-${\gamma}$ (Th1 cytokine). Furthermore, A wound healing effect of GBT was similar to external application of dexamethasone. Conclusions : These results suggest that GBT suppresses the inflammatory mediators and regulates the Thl/Th2 cytokines, and promotes the wound healing. Therefore, these properties may contribute to the strong anti-AD effect of GBT.

• Journal of Information Processing Systems
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• v.4 no.2
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• pp.41-52
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• 2008

In this paper, we discuss a novel reservation-based, asynchronous MAC protocol called 'Multi-rate Multi-hop MAC Protocol' (MMMP) for multi-hop ad hoc networks that provides QoS guarantees for multimedia traffic. MMMP achieves this by providing service differentiation for multirate real-time traffic (both constant and variable bit rate traffic) and guaranteeing a bounded end-to-end delay for the same while still catering to the throughput requirements of non real time traffic. In addition, it administers bandwidth preservation via a feature called 'Smart Drop' and implements efficient bandwidth usage through a mechanism called 'Release Bandwidth'. Simulation results on the QualNet simulator indicate that MMMP outperforms IEEE 802.11 on all performance metrics and can efficiently handle a large range of traffic intensity. It also outperforms other similar state-of-the-art MAC protocols.

• International Journal of Contents
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• v.2 no.2
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• pp.29-31
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• 2006

Mobile Ad hoc network is a self configuring network of mobile nodes. It allows mobile nodes to configure network spontaneously and share their services. In these networks, service discovery is very important because all nodes do not have same resources in term of memory and computing power. Nodes need to use different services offered by different servers. Some service discovery protocols have been proposed in last couple of years but they include significant traffic overhead and for small scale MANETS. In this paper, we present extensible lookup service scheme based on distributed mechanism. In our scheme neighboring nodes of service provider monitor service provider and send notification to lookup server when the service provider terminates its services unexpectedly. Lookup server can find other service provider or other alternative services in advance because of advance notification method and can provide consistent lookup services. In our scheme neighboring nodes also monitor lookup server and send notification to network when lookup server terminates unexpectedly. Simulation results show that our scheme can reduce up to 70% and 30% lookup failure as compare to centralize and simple distributed mechanism respectively.

• Proceedings of the PSK Conference
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• 2003.04a
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• pp.150-151
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• 2003

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the progressive deterioration of cognition and memory in association with widespread neuronal loss. AD is supposed to be very often associated with missense mutation located on homologous protein Presenilin (PS1) and (PS2). Up to now, the molecular mechanisms underlying the role of the gene mutation in AD still remain unclear. (omitted)

• IEMEK Journal of Embedded Systems and Applications
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• v.1 no.2
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• pp.31-36
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• 2006

As two dimensional bar code can collect data and information quickly, it is used and recognized as a useful tool for the many industrial application field. But the information capacity of two dimensional bar code is still limited. Recently, the two dimensional AD bar code (analog-digital code) that can increase its application range and overcome capacity limitation is developed. In this paper, we implement an effective system which can transform text information into voice using two dimensional AD bar code and TTS(Text To Speech). It can be transmitted to blind people by capturing the AD bar code on the papers or the books.

• Proceedings of the IEEK Conference
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• 2001.06a
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• pp.29-32
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• 2001

This paper has simulated the PER(Packet Error Rate), ratio of received packet and payload BER of Bluetooth system with packet types of ACL(Asynchronous Connection Less) and SCO(Synchronous Connection Oriented) link over wireless Ad-hoc environment. AWGN(Additive White Gaussian Noise) and Rayleigh fading are considered as channel model, and the analysis is based on the baseband model of Bluetooth system. In terms of PER and ratio of received packet, performance of DM1 packet is almost same as those of HV1, HV2 and HV3 packets, the performances of the other packets depend on the packet types. In terms of payload BER performance, there is no difference among HV2 packet of SCO link and DM1, DM3, DM5 packets of ACL link. Moreover, there is no difference among HV3 packet of SCO link and DM1, DM3, DM5 packets of ACL link, too.

• Korean Membrane Journal
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• v.1 no.1
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• pp.50-58
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• 1999

Symmetric asymmetric and composite perfluoropolymer membranes made with HYFLON AD have been prepared and evaluated. Porous and non porous symmetric membranes have been prepared by solvent evaporation with various processing conditions. Non-contact atomic force microscopy (AFM) was used to investigate the membrane morphology in air. Analysis of the images gave quantitative imformation on the surface pore strcture in particular on the pore size distributin. Possible useful uses of porous membranes are envisaged in the field of gas-liquid separations such as membrane contactors (MSc) Molecular Dynamics(MD) simulations structure of HYFLON AD 60X copolymer supporting these results are also reported. Amorphous perfluoropolymer membranes appears to be ideal other than in MCs when separation processes have to be performed in hostile environments i.e. high temperatures and aggressive non-aqueous media such as chemicals and solvents. In these cases HYFLON AD mem-branes can exploit the outstanding resistance of perfluoropolymers.