• 콘크리트학회지
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• 제20권6호
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• pp.28-35
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• 2008

700미터 이상의 높이와 160층 이상으로 설계된 버즈두바이가 완공되면 버즈두바이는 인간이 건축한 건축물 중에서 최고높이의 건축물이 될 것이다. 바람의 동적효과를 완화하고 제어시키는 것이 가장 중요한 설계요소중의 하나이며, 설계초기의 공기역학적 형상과 풍공학에 대한 고려가 이러한 주상복합건물의 건축적 형상 및 디자인에 있어 큰 역할을 하는 반면, 건물의 구조시스템을 위한 재료 선택 또한 디자인의 중요한 요소이고 그 다음으로 세부적인 재료기술에 대한 평가 및 기술자 수급이 요구되어진다. 콘크리트는 콘크리트의 강도, 강성, 감쇠, 잉여력, 형틀성, 내화성, 시공성, 원가 등을 고려하여 선정된다. 이 논문은 콘크리트를 활용한 구조시스템을 적용하면서의 설계적으로 도전되었던 부분과 버즈두바이의 콘크리트공사의 초기계획에 대해 집중적으로 다룰 것이다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제43권6호
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• pp.373-387
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• 2017

Objectives: The purpose of this study was to introduce our three experiments on bone morphogenetic protein (BMP) and its carriers performed using the critical sized segmental defect (CSD) model in rat fibula and to investigate development of animal models and carriers for more effective bone regeneration. Materials and Methods: For the experiments, 14, 16, and 24 rats with CSDs on both fibulae were used in Experiments 1, 2, and 3, respectively. BMP-2 with absorbable collagen sponge (ACS) (Experiments 1 and 2), autoclaved autogenous bone (AAB) and fibrin glue (FG) (Experiment 3), and xenogenic bone (Experiment 2) were used in the experimental groups. Radiographic and histomorphological evaluations were performed during the follow-up period of each experiment. Results: Significant new bone formation was commonly observed in all experimental groups using BMP-2 compared to control and xenograft (porcine bone) groups. Although there was some difference based on BMP carrier, regenerated bone volume was typically reduced by remodeling after initially forming excessive bone. Conclusion: BMP-2 demonstrates excellent ability for bone regeneration because of its osteoinductivity, but efficacy can be significantly different depending on its delivery system. ACS and FG showed relatively good bone regeneration capacity, satisfying the essential conditions of localization and release-control when used as BMP carriers. AAB could not provide release-control as a BMP carrier, but its space-maintenance role was remarkable. Carriers and scaffolds that can provide sufficient support to the BMP/carrier complex are necessary for large bone defects, and AAB is thought to be able to act as an effective scaffold. The CSD model of rat fibula is simple and useful for initial estimate of bone regeneration by agents including BMPs.