• Parasites, Hosts and Diseases
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• v.35 no.2
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• pp.119-126
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• 1997

Acanthnmoebn sp. YM-4 is simitar to A. culbertsoni based upon morphological characteristics of trophozoites and cysts. However, based on other characteristics, pathogenicity to mice, in uitro cytotoxicity and isoenzyme patterns, Acanthomoebo sp. YM- 4 was quite different from A. culbertsoni. Restriction fragment length polymorphism (RFLP) analysis of mtDNA is useful in the classification of members belonging to the genus Acanthcmoebn. Therefore, in this study, RFLP analysis of Acnnthcmoeba mtDNAs was accomplished using five restriction enzymes: Hnelll, Hinull, Clcl, Pudl and ScE. Each restriction enzyme produced approximately 3-15 fragments (range: from 0:6 kip to 34.4 kbp) . The mtDNA genome size, calculated by the summation of restriction fragments, averaged 46.4 kbp in Acnnthamoeba sp. YM-4,48.3 kbp in A. culbertsoni and 48.8 kbp in A. polyphaic, respectively. Digested mtDNA fragments of Accnthcmoeba sp. YM-4 contained nine and seven same size fragments, respectively, from a total of 67 and 69 fragments observed in A. culbertsoni and A. polyphcgn. An estimate of the genetic divergence was 10.1% between Acanthamoebc sp. YM-4 and A. culbertsoni, and 9.9% between Acanthamoebn sp. YM-4 and A. polyphcga.

• Journal of Pharmaceutical Investigation
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• v.17 no.2
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• pp.61-65
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• 1987

4-Pivaloyloxy, 4-benzenesulfonyloxy and 4-p-toluenesulfonyloxy compounds of piroxicam (2a, 2b and 2c) and isoxicam(4a, 4b and 4c) were synthesized in fairly good yield. Antiinflammatory and ulcerogenic effects of the 6 compounds were determined. Antiinflammatory effect of 2a was comparable to that of piroxicam and ulcerogenic effect of 2a was less than that of piroxicam.

• Journal of the Korean Mathematical Society
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• v.44 no.4
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• pp.757-766
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• 2007

In this note we construct an anti-symplectic involution on the non-$K\ddot{a}hler$, symplectic 4-manifold which is constructed by Thurston and show that the quotient of the Thurston's 4-manifold is not symplectic. Also we construct a non-$K\ddot{a}hler$, symplectic 4-manifold using the Gomph's symplectic sum method and an anti-symplectic involution on the non-$K\ddot{a}hler$, symplectic 4-manifold.

• Journal of Life Science
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• v.20 no.3
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• pp.416-423
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• 2010

In this study, the properties and gene expression of the lactate dehydrogenase (EC 1.1.1.27, LDH) isozyme were studied in angelfish (Pterophyllum scalare) - known for their adaptation to the low oxygen environment of the tropics - which were acclimated to acute temperature change ($27{\pm}0.5{\rightarrow}18{\pm}0.5^{\circ}C$) and dissolved oxygen (DO) change ($6{\pm}1{\rightarrow}18\;ppm$) for 2 hours. The properties of the LDH isozymes were confirmed in the native-polyacrylamide gel electrophoresis, Western blot analysis and enzyme activity measurement. Liver- and eye-specific Ldh-C gene were expressed in liver, eye and brain tissues. Through Western blot analysis, the LDH $A_4$ isozyme was shown to have a more cathodal mobility relative to the $B_4$ isozyme. In the liver tissue, the LDH $A_4$ isozyme increased with temperature drop while the $B_4$ isozyme decreased. The LDH $A_4$ and $C_4$ isozymes increased with DO increment, while the $B_4$ isozyme decreased. In the eye tissue, the LDH $A_4$ and B4 isozymse increased with temperature drop while the $B_4$ isozyme decreased. The LDH $A_4$ and $B_4$ isozymes increased with DO increment, but the $C_4$ isozyme and isozymes including the subunit C decreased. In the heart tissue, LDH activity increased with DO increment, as well as the LDH $B_4$ isozyme. In the brain tissue, the LDH $A_4$ and $B_4$ isozymes increased with temperature drop. The LDH $B_4$ isozyme increased with DO increment. Accordingly, since the liver- and eye-specific Ldh-C are influenced by changes in DO and the LDH $B_4$ and $C_4$ isozymes are relatively controlled in the liver and eye tissues, the $C_4$ isozyme can be considered to have a lactate oxidase function.

• Applied Chemistry for Engineering
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• v.28 no.3
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• pp.286-289
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• 2017

Synthesis of zeolite 4A was carried out to optimize the nanoparticle synthesis process using statistical experimental design method. The zeolite 4A was synthesized by controlling the concentration of the silicon precursor, sodium metasilicate (SMS), and characterized by XRD, SEM and nitrogen adsorption. In particular, the property of zeolite 4A can be determined by XRD analysis. Using the general factor analysis in the design of experiments, we analyzed main effects and interactions according to the reactor, reaction temperature and reaction time. The optimum reaction condition for the synthesis of zeolite 4A crystallinity was using an autoclave for 3 hours at $110^{\circ}C$. Furthermore, the optimal synthesis conditions of zeolite 4A with various crystallinity using Ludox as a silicon precursor were presented of what using both the surface and contour plot.

• The Transactions of the Korean Institute of Power Electronics
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• v.12 no.3
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• pp.205-212
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• 2007

This paper presents a direct instantaneous torque control (DITC) of Switched Reluctance Motor (SRM) with a novel 4-level converter to develop a uniform torque and to improve a dynamic performance. The DITC method can reduce a high torque ripple of SRM. Drive efficiency and dynamic performance with conventional drive are low due to a slow excitation current build-up. Since the 4-level converter can obtain an addition boosted voltage to have a fast excitation and demagnetization, it can Improve dynamic performance and efficiency easily. To apply the DITC technique to a 4-level converter, a novel control scheme is presented according to the operating modes. Additionally, selection of capacitances of boosted capacitor and efficiency improvement of 4-level converter are analyzed. At last, the validity of proposed method is verified by some computer simulations md comparative experiments.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.56 no.1
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• pp.161-166
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• 2007

In this paper, two 4$\times$4 rectangular patch array antennas operating at 20 GHz are implemented for the satellite communication. The sixteen patch antennas and microstrip feeding line are printed on a single-layered substrate. The design goal is to achieve high directivity and gain by optimizing design parameters through permutations in element spacing. The spacing between the array elements is chosen to be 0.736$\lambda$. Numerical simulation results indicate that the HPBW(Half-Power Beam Width) of the 4$\times$4 patch array antenna is 18.78 degrees in the E-plane and 18.48 degrees in the H-plane with a gain of 17.18 dBi. Numerical simulations of a 4$\times$4 recessed patch array antenna yield a HPBW of 18.71 degrees in the E-plane and 17.82 degrees in the H-plane with a gain of 19.43 dBi.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.66 no.2
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• pp.379-382
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• 2017

This paper proposes a $4{\times}4$ broadband phased array antenna using a Left-Handed Transmission Line (LHTL) based phase shifter. The phased array is constructed with sixteen quasi-Yagi antenna elements and the phase shifters, as well as four power dividers. A key component of the system, the LHTL based phase shifter is able to control a phase delay of incident waves linearly and continuously. The fabricated phased array antenna operate for a frequency range of 800 MHz (1.6 GHz~2.4 GHz). The beam scanning range of the $4{\times}4$ array antenna is ${\pm}27^{\circ}$ horizontally and vertically while the antenna gain is maintained with a variation of ${\pm}1.4dBi$.

• Korean Journal of Pharmacognosy
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• v.34 no.1 s.132
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• pp.86-90
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• 2003

For the determination of inhibiting cytochrome P450(CYP)3A4 activity, an improvement HPLC method was established by using a new internal standard and solvent system. Moreover, CYP3A4 amount for a optimum reaction of enzyme was determined by a comparative study with a variety concentration of enzyme. Using a established method, inhibitory effect of CYP3A4 that is drug metabolizing enzyme Investigated on EtOAc extracts of 5-class spices. As a result of experiment, EtOAc extract of white pepper (Piper nigrum L.) showed strong inhibitory activity. On a continuous experiment, the fraction 2, 4 and 5 of while pepper extract showed remarkable inhibitory activity. Pipeline, a main constituent of pepper was not included in these fraction. It is suggested that major compounds for the inhibitory activity of white pepper may be other ingredient that is not piperine.

• Journal of the Korean Chemical Society
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• v.36 no.5
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• pp.764-769
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• 1992

Strigol, a natural product isolated from root exudates of cotton, was found to be an extremely potent seed germination stimulant for the parasitic plant, witchweed. Witchweed seeds can remain dormant in the soil for several years until favorable conditions prevail including exposure to some type of chemical germination stimulant. Several strigol analogues, 3-methyl-4-(2-oxo-3,3a,6,6a-tetrahydro-2H-cyclopenta[b]furan-3-ylidenemethoxy)-but-2-en-4-olide(21), 4-(2-oxo-3,3a,6,6a-tetrahydro-2H-cyclopenta[b]furan-3-ylidenemethoxy)but-2-en-4-oilde(22), 3-methyl-4-(2-oxotetrahydrofuran-3-ylidenemethoxy)-but-2-en-4-olide(23), and 4-(2-oxotetrahydrofuran-3-ylidenemethoxy)-but-2-en-4-olide(24), were synthesized.